-
1
-
-
0035902141
-
The microenvironment of the tumour-host interface
-
Liotta LA, Kohn EC (2001) The microenvironment of the tumour-host interface. Nature 411: 375-379.
-
(2001)
Nature
, vol.411
, pp. 375-379
-
-
Liotta, L.A.1
Kohn, E.C.2
-
2
-
-
9244227134
-
Stromal fibroblasts in cancer initiation and progression
-
Bhowmick NA, Neilson EG, Moses HL (2004) Stromal fibroblasts in cancer initiation and progression. Nature 432: 332-337.
-
(2004)
Nature
, vol.432
, pp. 332-337
-
-
Bhowmick, N.A.1
Neilson, E.G.2
Moses, H.L.3
-
3
-
-
8144228952
-
Friends or foes - bipolar effects of the tumour stroma in cancer
-
Mueller MM, Fusenig NE (2004) Friends or foes - bipolar effects of the tumour stroma in cancer. Nat Rev Cancer 4: 839-849.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 839-849
-
-
Mueller, M.M.1
Fusenig, N.E.2
-
4
-
-
0037899253
-
Role of tissue stroma in cancer cell invasion
-
De Wever O, Mareel M (2003) Role of tissue stroma in cancer cell invasion. J Pathol 200: 429-447.
-
(2003)
J Pathol
, vol.200
, pp. 429-447
-
-
De Wever, O.1
Mareel, M.2
-
5
-
-
20444386530
-
Coevolution of cancer and stromal cellular responses
-
Littlepage LE, Egeblad M, Werb Z (2005) Coevolution of cancer and stromal cellular responses. Cancer Cell 7: 499-500.
-
(2005)
Cancer Cell
, vol.7
, pp. 499-500
-
-
Littlepage, L.E.1
Egeblad, M.2
Werb, Z.3
-
6
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
Egeblad M, Werb Z (2002) New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2: 161-174.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
7
-
-
0036995757
-
Matrix metalloproteinases in tumor-host cell communication
-
Lynch CC, Matrisian LM (2002) Matrix metalloproteinases in tumor-host cell communication. Differentiation 70: 561-573.
-
(2002)
Differentiation
, vol.70
, pp. 561-573
-
-
Lynch, C.C.1
Matrisian, L.M.2
-
8
-
-
0038575443
-
Extracellular matrix remodelling: The role of matrix metalloproteinases
-
Stamenkovic I (2003) Extracellular matrix remodelling: the role of matrix metalloproteinases. J Pathol 200: 448-464.
-
(2003)
J Pathol
, vol.200
, pp. 448-464
-
-
Stamenkovic, I.1
-
9
-
-
0034721666
-
MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
-
Coussens LM, Tinkle CL, Hanahan D, Werb Z (2000) MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 103: 481-490.
-
(2000)
Cell
, vol.103
, pp. 481-490
-
-
Coussens, L.M.1
Tinkle, C.L.2
Hanahan, D.3
Werb, Z.4
-
10
-
-
1642300508
-
Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment
-
Chantrain CF, Shimada H, Jodele S, Groshen S, Ye W, et al. (2004) Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment. Cancer Res 64: 1675-1686.
-
(2004)
Cancer Res
, vol.64
, pp. 1675-1686
-
-
Chantrain, C.F.1
Shimada, H.2
Jodele, S.3
Groshen, S.4
Ye, W.5
-
11
-
-
0035835829
-
Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation
-
Elenbaas B, Weinberg RA (2001) Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation. Exp Cell Res 264: 169-184.
-
(2001)
Exp Cell Res
, vol.264
, pp. 169-184
-
-
Elenbaas, B.1
Weinberg, R.A.2
-
12
-
-
20444412646
-
Therapeutic targeting of the tumor microenvironment
-
Joyce JA (2005) Therapeutic targeting of the tumor microenvironment. Cancer Cell 7: 513-520.
-
(2005)
Cancer Cell
, vol.7
, pp. 513-520
-
-
Joyce, J.A.1
-
13
-
-
2142717404
-
Gene expression profiling predicts clinical outcome of prostate cancer
-
Glinsky GV, Glinskii AB, Stephenson AJ, Hoffman RM, Gerald WL (2004) Gene expression profiling predicts clinical outcome of prostate cancer. J Clin Invest 113: 913-923.
-
(2004)
J Clin Invest
, vol.113
, pp. 913-923
-
-
Glinsky, G.V.1
Glinskii, A.B.2
Stephenson, A.J.3
Hoffman, R.M.4
Gerald, W.L.5
-
14
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
van de Vijver MJ, He YD, van't Veer LJ, Dai H, Hart AA, et al. (2002) A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 347: 1999-2009.
-
(2002)
N Engl J Med
, vol.347
, pp. 1999-2009
-
-
van de Vijver, M.J.1
He, Y.D.2
van't Veer, L.J.3
Dai, H.4
Hart, A.A.5
-
16
-
-
33646353175
-
The challenges of gene expression microarrays for the study of human cancer
-
Tinker AV, Boussioutas A, Bowtell DD (2006) The challenges of gene expression microarrays for the study of human cancer. Cancer Cell 9: 333-339.
-
(2006)
Cancer Cell
, vol.9
, pp. 333-339
-
-
Tinker, A.V.1
Boussioutas, A.2
Bowtell, D.D.3
-
17
-
-
0032446247
-
A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells
-
Garabedian EM, Humphrey PA, Gordon JI (1998) A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells. Proc Natl Acad Sci U S A 95: 15382-15387.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15382-15387
-
-
Garabedian, E.M.1
Humphrey, P.A.2
Gordon, J.I.3
-
18
-
-
0037113943
-
Molecular characterization of a metastatic neuroendocrine cell cancer arising in the prostates of transgenic mice
-
Hu Y, Ippolito JE, Garabedian EM, Humphrey PA, Gordon JI (2002) Molecular characterization of a metastatic neuroendocrine cell cancer arising in the prostates of transgenic mice. J Biol Chem 277: 44462-44474.
-
(2002)
J Biol Chem
, vol.277
, pp. 44462-44474
-
-
Hu, Y.1
Ippolito, J.E.2
Garabedian, E.M.3
Humphrey, P.A.4
Gordon, J.I.5
-
19
-
-
18544365698
-
Gene-expression profiles predict survival of patients with lung adenocarcinoma
-
Beer DG, Kardia SL, Huang CC, Giordano TJ, Levin AM, et al. (2002) Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 8: 816-824.
-
(2002)
Nat Med
, vol.8
, pp. 816-824
-
-
Beer, D.G.1
Kardia, S.L.2
Huang, C.C.3
Giordano, T.J.4
Levin, A.M.5
-
20
-
-
0037059002
-
Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis
-
Leung SY, Chen X, Chu KM, Yuen ST, Mathy J, et al. (2002) Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis. Proc Natl Acad Sci U S A 99: 16203-16208.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 16203-16208
-
-
Leung, S.Y.1
Chen, X.2
Chu, K.M.3
Yuen, S.T.4
Mathy, J.5
-
21
-
-
32144434202
-
Gene expression profiling predicts survival in conventional renal cell carcinoma
-
Zhao H, Ljungberg B, Grankvist K, Rasmuson T, Tibshirani R, et al. (2006) Gene expression profiling predicts survival in conventional renal cell carcinoma. PLoS Med 3: e13.
-
(2006)
PLoS Med
, vol.3
-
-
Zhao, H.1
Ljungberg, B.2
Grankvist, K.3
Rasmuson, T.4
Tibshirani, R.5
-
22
-
-
0029808255
-
Cathepsin D in host stromal cells, but not in tumor cells, is associated with aggressive behavior in node-negative breast cancer
-
Nadji M, Fresno M, Nassiri M, Conner G, Herrero A, et al. (1996) Cathepsin D in host stromal cells, but not in tumor cells, is associated with aggressive behavior in node-negative breast cancer. Hum Pathol 27: 890-895.
-
(1996)
Hum Pathol
, vol.27
, pp. 890-895
-
-
Nadji, M.1
Fresno, M.2
Nassiri, M.3
Conner, G.4
Herrero, A.5
-
23
-
-
22244441842
-
An integrated functional genomics and metabolomics approach for defining poor prognosis in human neuroendocrine cancers
-
Ippolito JE, Xu J, Jain S, Moulder K, Mennerick S, et al. (2005) An integrated functional genomics and metabolomics approach for defining poor prognosis in human neuroendocrine cancers. Proc Natl Acad Sci U S A 102: 9901-9906.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9901-9906
-
-
Ippolito, J.E.1
Xu, J.2
Jain, S.3
Moulder, K.4
Mennerick, S.5
-
24
-
-
0030788411
-
The urokinase-type plasminogen activator system in cancer metastasis: A review
-
Andreasen PA, Kjoller L, Christensen L, Duffy MJ (1997) The urokinase-type plasminogen activator system in cancer metastasis: a review. Int J Cancer 72: 1-22.
-
(1997)
Int J Cancer
, vol.72
, pp. 1-22
-
-
Andreasen, P.A.1
Kjoller, L.2
Christensen, L.3
Duffy, M.J.4
-
26
-
-
33645825183
-
Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer
-
Ein-Dor L, Zuk O, Domany E (2006) Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer. Proc Natl Acad Sci U S A 103: 5923-5928.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 5923-5928
-
-
Ein-Dor, L.1
Zuk, O.2
Domany, E.3
-
27
-
-
22744445394
-
Determination of stromal signatures in breast carcinoma
-
West RB, Nuyten DS, Subramanian S, Nielsen TO, Corless CL, et al. (2005) Determination of stromal signatures in breast carcinoma. PLoS Biol 3: e187.
-
(2005)
PLoS Biol
, vol.3
-
-
West, R.B.1
Nuyten, D.S.2
Subramanian, S.3
Nielsen, T.O.4
Corless, C.L.5
-
28
-
-
19344363035
-
Gene expression signature of fibroblast serum response predicts human cancer progression: Similarities between tumors and wounds
-
Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, et al. (2004) Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol 2: E7.
-
(2004)
PLoS Biol
, vol.2
-
-
Chang, H.Y.1
Sneddon, J.B.2
Alizadeh, A.A.3
Sood, R.4
West, R.B.5
-
29
-
-
20144386127
-
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
-
Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, et al. (2005) Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci U S A 102: 3738-3743.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3738-3743
-
-
Chang, H.Y.1
Nuyten, D.S.2
Sneddon, J.B.3
Hastie, T.4
Tibshirani, R.5
-
30
-
-
3142512612
-
Molecular characterization of the tumor microenvironment in breast cancer
-
Allinen M, Beroukhim R, Cai L, Brennan C, Lahti-Domenici J, et al. (2004) Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell 6: 17-32.
-
(2004)
Cancer Cell
, vol.6
, pp. 17-32
-
-
Allinen, M.1
Beroukhim, R.2
Cai, L.3
Brennan, C.4
Lahti-Domenici, J.5
-
31
-
-
33745928466
-
The emerging role of pituitary tumor transforming gene in tumorigenesis
-
Tfelt-Hansen J, Kanuparthi D, Chattopadhyay N (2006) The emerging role of pituitary tumor transforming gene in tumorigenesis. Clin Med Res 4: 130-137.
-
(2006)
Clin Med Res
, vol.4
, pp. 130-137
-
-
Tfelt-Hansen, J.1
Kanuparthi, D.2
Chattopadhyay, N.3
-
32
-
-
2342603891
-
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis
-
Joyce JA, Baruch A, Chehade K, Meyer-Morse N, Giraudo E, et al. (2004) Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell 5: 443-453.
-
(2004)
Cancer Cell
, vol.5
, pp. 443-453
-
-
Joyce, J.A.1
Baruch, A.2
Chehade, K.3
Meyer-Morse, N.4
Giraudo, E.5
-
33
-
-
33644784910
-
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis
-
Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, et al. (2006) Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes Dev 20: 543-556.
-
(2006)
Genes Dev
, vol.20
, pp. 543-556
-
-
Gocheva, V.1
Zeng, W.2
Ke, D.3
Klimstra, D.4
Reinheckel, T.5
-
34
-
-
15544384612
-
Involvement of cathepsins in the invasion, metastasis and proliferation of cancer cells
-
Nomura T, Katunuma N (2005) Involvement of cathepsins in the invasion, metastasis and proliferation of cancer cells. J Med Invest 52: 1-9.
-
(2005)
J Med Invest
, vol.52
, pp. 1-9
-
-
Nomura, T.1
Katunuma, N.2
-
35
-
-
17144394796
-
Multiple roles for cysteine cathepsins in cancer
-
Joyce JA, Hanahan D (2004) Multiple roles for cysteine cathepsins in cancer. Cell Cycle 3: 1516-1619.
-
(2004)
Cell Cycle
, vol.3
, pp. 1516-1619
-
-
Joyce, J.A.1
Hanahan, D.2
-
36
-
-
13444266042
-
Catalytically inactive human cathepsin D triggers fibroblast invasive growth
-
Laurent-Matha V, Maruani-Herrmann S, Prebois C, Beaujouin M, Glondu M, et al. (2005) Catalytically inactive human cathepsin D triggers fibroblast invasive growth. J Cell Biol 168: 489-499.
-
(2005)
J Cell Biol
, vol.168
, pp. 489-499
-
-
Laurent-Matha, V.1
Maruani-Herrmann, S.2
Prebois, C.3
Beaujouin, M.4
Glondu, M.5
-
37
-
-
33745240353
-
Cross-species oncogenomics in cancer gene identification
-
Peeper D, Berns A (2006) Cross-species oncogenomics in cancer gene identification. Cell 125: 1230-1233.
-
(2006)
Cell
, vol.125
, pp. 1230-1233
-
-
Peeper, D.1
Berns, A.2
-
38
-
-
33745253109
-
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
-
Zender L, Spector MS, Xue W, Flemming P, Cordon-Cardo C, et al. (2006) Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell 125: 1253-1267.
-
(2006)
Cell
, vol.125
, pp. 1253-1267
-
-
Zender, L.1
Spector, M.S.2
Xue, W.3
Flemming, P.4
Cordon-Cardo, C.5
-
39
-
-
33745288277
-
Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene
-
Kim M, Gans JD, Nogueira C, Wang A, Paik JH, et al. (2006) Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Cell 125: 1269-1281.
-
(2006)
Cell
, vol.125
, pp. 1269-1281
-
-
Kim, M.1
Gans, J.D.2
Nogueira, C.3
Wang, A.4
Paik, J.H.5
-
40
-
-
11244258643
-
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis
-
Sweet-Cordero A, Mukherjee S, Subramanian A, You H, Roix JJ, et al. (2005) An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis. Nat Genet 37: 48-55.
-
(2005)
Nat Genet
, vol.37
, pp. 48-55
-
-
Sweet-Cordero, A.1
Mukherjee, S.2
Subramanian, A.3
You, H.4
Roix, J.J.5
-
41
-
-
12944257429
-
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray
-
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, et al. (2000) Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Proc Natl Acad Sci U S A 97: 9127-9132.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 9127-9132
-
-
Tanaka, T.S.1
Jaradat, S.A.2
Lim, M.K.3
Kargul, G.J.4
Wang, X.5
-
42
-
-
1342294092
-
Normalization for cDNA microarray data: A robust composite method addressing single and multiple slide systematic variation
-
Yang YH, Dudoit S, Luu P, Lin DM, Peng V, et al. (2002) Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res 30: e15.
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Yang, Y.H.1
Dudoit, S.2
Luu, P.3
Lin, D.M.4
Peng, V.5
-
43
-
-
0242333835
-
Normalization of cDNA microarray data
-
Smyth G, Speed T (2003) Normalization of cDNA microarray data. Methods 31: 265-273.
-
(2003)
Methods
, vol.31
, pp. 265-273
-
-
Smyth, G.1
Speed, T.2
-
44
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B57: 289.
-
(1995)
J R Statist Soc
, vol.B57
, pp. 289
-
-
Benjamini, Y.1
Hochberg, Y.2
-
45
-
-
0034069495
-
Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, et al. (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25: 25-29.
-
(2000)
Nat Genet
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
Ball, C.A.2
Blake, J.A.3
Botstein, D.4
Butler, H.5
-
46
-
-
13444251422
-
-
Hubbard T, Andrews D, Caccamo M, Cameron G, Chen Y, et al. (2005) Ensembl 2005. Nucleic Acids Res 33: D447-453.
-
(2005)
Ensembl 2005. Nucleic Acids Res
, vol.33
-
-
Hubbard, T.1
Andrews, D.2
Caccamo, M.3
Cameron, G.4
Chen, Y.5
-
47
-
-
9144269670
-
EnsMart: A generic system for fast and flexible access to biological data
-
Kasprzyk A, Keefe D, Smedley D, London D, Spooner W, et al. (2004) EnsMart: a generic system for fast and flexible access to biological data. Genome Res 14: 160-169.
-
(2004)
Genome Res
, vol.14
, pp. 160-169
-
-
Kasprzyk, A.1
Keefe, D.2
Smedley, D.3
London, D.4
Spooner, W.5
|