-
1
-
-
1642396348
-
Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta
-
Abbas T., White D., Hui L., Yoshida D.A., and Bargonetti J. Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta. J Biol Chem 279 (2004) 9970-9977
-
(2004)
J Biol Chem
, vol.279
, pp. 9970-9977
-
-
Abbas, T.1
White, D.2
Hui, L.3
Yoshida, D.A.4
Bargonetti, J.5
-
2
-
-
0028951290
-
High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumors and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions
-
Ahomadegbe J.C., Barrois M., Fogel S., Le Bihan M.L., Douc-Rasy S., Duvillard P., Armand J.P., and Riou G. High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumors and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions. Oncogene 10 (1995) 1217-1227
-
(1995)
Oncogene
, vol.10
, pp. 1217-1227
-
-
Ahomadegbe, J.C.1
Barrois, M.2
Fogel, S.3
Le Bihan, M.L.4
Douc-Rasy, S.5
Duvillard, P.6
Armand, J.P.7
Riou, G.8
-
3
-
-
0037444398
-
Is the p53 inactivation frequency in squamous cell carcinomas of the head and neck underestimated? Analysis of p53 exons 2-11 and human papillomavirus 16/18 E6 transcripts in 123 unselected tumor specimens
-
Balz V., Scheckenbach K., Gotte K., Bockmuhl U., Petersen I., and Bier H. Is the p53 inactivation frequency in squamous cell carcinomas of the head and neck underestimated? Analysis of p53 exons 2-11 and human papillomavirus 16/18 E6 transcripts in 123 unselected tumor specimens. Cancer Res 63 (2003) 1188-1191
-
(2003)
Cancer Res
, vol.63
, pp. 1188-1191
-
-
Balz, V.1
Scheckenbach, K.2
Gotte, K.3
Bockmuhl, U.4
Petersen, I.5
Bier, H.6
-
4
-
-
10744230945
-
p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis
-
Bergamaschi D., Gasco M., Hiller L., Sullivan A., Syed N., Trigante G., Yulug I., Merlano M., Numico G., Comino A., Attard M., Reelfs O., Gusterson B., Bell A.K., Heath V., Tavassoli M., Farrell P.J., Smith P., Lu X., and Crook T. p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis. Cancer Cell 3 (2003) 387-402
-
(2003)
Cancer Cell
, vol.3
, pp. 387-402
-
-
Bergamaschi, D.1
Gasco, M.2
Hiller, L.3
Sullivan, A.4
Syed, N.5
Trigante, G.6
Yulug, I.7
Merlano, M.8
Numico, G.9
Comino, A.10
Attard, M.11
Reelfs, O.12
Gusterson, B.13
Bell, A.K.14
Heath, V.15
Tavassoli, M.16
Farrell, P.J.17
Smith, P.18
Lu, X.19
Crook, T.20
more..
-
5
-
-
0037312920
-
iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human
-
Bergamaschi D., Samuels Y., O'Neil N.J., Trigiante G., Crook T., Hsieh J.K., O'Connor D.J., Zhong S., Campargue I., Tomlinson M.L., Kuwabara P.E., and Lu X. iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human. Nat Genet 33 (2003) 162-167
-
(2003)
Nat Genet
, vol.33
, pp. 162-167
-
-
Bergamaschi, D.1
Samuels, Y.2
O'Neil, N.J.3
Trigiante, G.4
Crook, T.5
Hsieh, J.K.6
O'Connor, D.J.7
Zhong, S.8
Campargue, I.9
Tomlinson, M.L.10
Kuwabara, P.E.11
Lu, X.12
-
6
-
-
0041342137
-
p53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines
-
Bradford C.R., Zhu S., Ogawa H., Ogawa T., Ubell M., Narayan A., Johnson G., Wolf G.T., Fisher S.G., and Carey T.E. p53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines. Head Neck 25 (2003) 654-661
-
(2003)
Head Neck
, vol.25
, pp. 654-661
-
-
Bradford, C.R.1
Zhu, S.2
Ogawa, H.3
Ogawa, T.4
Ubell, M.5
Narayan, A.6
Johnson, G.7
Wolf, G.T.8
Fisher, S.G.9
Carey, T.E.10
-
7
-
-
0028814029
-
Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck
-
Brennan J.A., Mao L., Hruban R.H., Boyle J.O., Eby Y.J., Koch W.M., Goodman S.N., and Sidransky D. Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. N Engl J Med 332 (1995) 429-435
-
(1995)
N Engl J Med
, vol.332
, pp. 429-435
-
-
Brennan, J.A.1
Mao, L.2
Hruban, R.H.3
Boyle, J.O.4
Eby, Y.J.5
Koch, W.M.6
Goodman, S.N.7
Sidransky, D.8
-
8
-
-
3843090814
-
Head and neck tumor sites differ in prevalence and spectrum of p53 alterations but these have limited prognostic value
-
Bosch F.X., Ritter D., Enders C., Flechtenmacher C., Abel U., Dietz A., Hergenhahn M., and Weidauer H. Head and neck tumor sites differ in prevalence and spectrum of p53 alterations but these have limited prognostic value. Int J Cancer 111 (2004) 530-538
-
(2004)
Int J Cancer
, vol.111
, pp. 530-538
-
-
Bosch, F.X.1
Ritter, D.2
Enders, C.3
Flechtenmacher, C.4
Abel, U.5
Dietz, A.6
Hergenhahn, M.7
Weidauer, H.8
-
9
-
-
0027524636
-
The incidence of p53 mutations increases with progression of head and neck cancer
-
Boyle J.O., Hakim J., Koch W., van der Riet P., Hruban R.H., Roa R.A., Correo R., Eby Y.J., Ruppert J.M., and Sidransky D. The incidence of p53 mutations increases with progression of head and neck cancer. Cancer Res 53 (1993) 4477-4480
-
(1993)
Cancer Res
, vol.53
, pp. 4477-4480
-
-
Boyle, J.O.1
Hakim, J.2
Koch, W.3
van der Riet, P.4
Hruban, R.H.5
Roa, R.A.6
Correo, R.7
Eby, Y.J.8
Ruppert, J.M.9
Sidransky, D.10
-
10
-
-
0036128899
-
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
-
Bykov V.J., Issaeva N., Shilov A., Hultcrantz M., Pugacheva E., Chumakov P., Bergman J., Wiman K.G., and Selivanova G. Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound. Nat Med 8 (2002) 282-288
-
(2002)
Nat Med
, vol.8
, pp. 282-288
-
-
Bykov, V.J.1
Issaeva, N.2
Shilov, A.3
Hultcrantz, M.4
Pugacheva, E.5
Chumakov, P.6
Bergman, J.7
Wiman, K.G.8
Selivanova, G.9
-
11
-
-
0034086197
-
p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series
-
Cabelguenne A., Blons H., de Waziers I., Carnot F., Houllier A.M., Soussi T., Brasnu D., Beaune P., Laccourreye O., and Laurent-Puig P. p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series. J Clin Oncol 18 (2000) 1465-1473
-
(2000)
J Clin Oncol
, vol.18
, pp. 1465-1473
-
-
Cabelguenne, A.1
Blons, H.2
de Waziers, I.3
Carnot, F.4
Houllier, A.M.5
Soussi, T.6
Brasnu, D.7
Beaune, P.8
Laccourreye, O.9
Laurent-Puig, P.10
-
12
-
-
0034092061
-
Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53
-
Cai Y.C., Yang G.Y., Nie Y., Wang L.D., Zhao X., Song Y.L., Seril D.N., Liao J., Xing E.P., and Yang C.S. Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53. Carcinogenesis 21 (2000) 683-689
-
(2000)
Carcinogenesis
, vol.21
, pp. 683-689
-
-
Cai, Y.C.1
Yang, G.Y.2
Nie, Y.3
Wang, L.D.4
Zhao, X.5
Song, Y.L.6
Seril, D.N.7
Liao, J.8
Xing, E.P.9
Yang, C.S.10
-
13
-
-
0036214558
-
Differential expression of p53 gene family members p63 and p7P3 in head and neck squamous tumorigenesis
-
Choi H.R., Batsakis J.G., Zhan F., Sturgis E., Luna M.A., and El-Naggar A.K. Differential expression of p53 gene family members p63 and p7P3 in head and neck squamous tumorigenesis. Hum Pathol 33 (2002) 158-164
-
(2002)
Hum Pathol
, vol.33
, pp. 158-164
-
-
Choi, H.R.1
Batsakis, J.G.2
Zhan, F.3
Sturgis, E.4
Luna, M.A.5
El-Naggar, A.K.6
-
14
-
-
0031750168
-
Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma
-
Clayman G.L., El-Naggar A.K., Lippman S.M., Henderson Y.C., Frederick M., Merritt J.A., Zumstein L.A., Timmons T.M., Liu T.J., Ginsberg L., Roth J.A., Hong W.K., Bruso P., and Goepfert H. Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma. J Clin Oncol 16 (1998) 2221-2232
-
(1998)
J Clin Oncol
, vol.16
, pp. 2221-2232
-
-
Clayman, G.L.1
El-Naggar, A.K.2
Lippman, S.M.3
Henderson, Y.C.4
Frederick, M.5
Merritt, J.A.6
Zumstein, L.A.7
Timmons, T.M.8
Liu, T.J.9
Ginsberg, L.10
Roth, J.A.11
Hong, W.K.12
Bruso, P.13
Goepfert, H.14
-
15
-
-
0032809839
-
Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers
-
Clayman G.L., Frank D.K., Bruso P.A., and Goepfert H. Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers. Clin Cancer Res 5 (1999) 1715-1722
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1715-1722
-
-
Clayman, G.L.1
Frank, D.K.2
Bruso, P.A.3
Goepfert, H.4
-
16
-
-
0031637675
-
p53 mutations and chemoresistance in oromaxillofacial squamous-cell carcinomas. The results of a molecular genetics study of p53 in metastatic tumors and an evaluation of the response to neoadjuvant chemotherapeutic treatment
-
Cutilli T., Papola F., Di Emidio P., Leocata P., and Corbacelli A. p53 mutations and chemoresistance in oromaxillofacial squamous-cell carcinomas. The results of a molecular genetics study of p53 in metastatic tumors and an evaluation of the response to neoadjuvant chemotherapeutic treatment. Minerva Stomatol 47 (1998) 1-9
-
(1998)
Minerva Stomatol
, vol.47
, pp. 1-9
-
-
Cutilli, T.1
Papola, F.2
Di Emidio, P.3
Leocata, P.4
Corbacelli, A.5
-
17
-
-
1642515808
-
Human papillomavirus type 16 and TP53 mutation in oral cancer: matched analysis of the IARC multicenter study
-
IARC Multicenter Oral Cancer Study Group
-
Dai M., Clifford G.M., le Calvez F., Castellsage X., Snijders P.J., Pawlita M., Herrero R., Hainaut P., Franceschi S., and IARC Multicenter Oral Cancer Study Group. Human papillomavirus type 16 and TP53 mutation in oral cancer: matched analysis of the IARC multicenter study. Cancer Res 64 (2004) 468-471
-
(2004)
Cancer Res
, vol.64
, pp. 468-471
-
-
Dai, M.1
Clifford, G.M.2
le Calvez, F.3
Castellsage, X.4
Snijders, P.J.5
Pawlita, M.6
Herrero, R.7
Hainaut, P.8
Franceschi, S.9
-
18
-
-
0029806936
-
Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in p53
-
Denissenko M.F., Pao A., Tang M., and Pfeifer G.P. Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in p53. Science 274 (1996) 430-432
-
(1996)
Science
, vol.274
, pp. 430-432
-
-
Denissenko, M.F.1
Pao, A.2
Tang, M.3
Pfeifer, G.P.4
-
19
-
-
18244379872
-
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
-
D'Orazi G., Cecchinelli B., Bruno T., Manni I., Higashimoto Y., Saito S., Gostissa M., Coen S., Marchetti A., Del Sal G., Piaggio G., Fanciulli M., Appella E., and Soddu S. Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. Nat Cell Biol 4 (2002) 11-19
-
(2002)
Nat Cell Biol
, vol.4
, pp. 11-19
-
-
D'Orazi, G.1
Cecchinelli, B.2
Bruno, T.3
Manni, I.4
Higashimoto, Y.5
Saito, S.6
Gostissa, M.7
Coen, S.8
Marchetti, A.9
Del Sal, G.10
Piaggio, G.11
Fanciulli, M.12
Appella, E.13
Soddu, S.14
-
20
-
-
0037372005
-
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
-
Dumont P.J., Leu I.-J., Pietra III A.C.D., George D.L., and Murphy M. The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat Genet 33 (2003) 357-365
-
(2003)
Nat Genet
, vol.33
, pp. 357-365
-
-
Dumont, P.J.1
Leu, I.-J.2
Pietra III, A.C.D.3
George, D.L.4
Murphy, M.5
-
21
-
-
18144412429
-
Guilt by association? p53 and the development of aneuploidy in cancer
-
Duensing A., and Duensing S. Guilt by association? p53 and the development of aneuploidy in cancer. Biochem Biophys Res Commun 331 (2005) 694-700
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 694-700
-
-
Duensing, A.1
Duensing, S.2
-
22
-
-
0029057157
-
Sequential p53 mutation analysis of pre-invasive and invasive head and neck squamous carcinoma
-
El-Naggar A.K., Lai S., Luna M.A., Zhou X.D., Weber R.S., Goepfert H., and Batsakis J.G. Sequential p53 mutation analysis of pre-invasive and invasive head and neck squamous carcinoma. Int J Cancer 64 (1995) 196-201
-
(1995)
Int J Cancer
, vol.64
, pp. 196-201
-
-
El-Naggar, A.K.1
Lai, S.2
Luna, M.A.3
Zhou, X.D.4
Weber, R.S.5
Goepfert, H.6
Batsakis, J.G.7
-
23
-
-
4644316645
-
Molecular profiles as predictive marker for the effect of overall treatment time of radiotherapy in supraglottic larynx squamous cell carcinomas
-
Eriksen J.G., Buffa F.M., Alsner J., Steiniche T., Bentzen S.M., and Overgaard J. Molecular profiles as predictive marker for the effect of overall treatment time of radiotherapy in supraglottic larynx squamous cell carcinomas. Radiother Oncol 72 (2004) 275-282
-
(2004)
Radiother Oncol
, vol.72
, pp. 275-282
-
-
Eriksen, J.G.1
Buffa, F.M.2
Alsner, J.3
Steiniche, T.4
Bentzen, S.M.5
Overgaard, J.6
-
24
-
-
0037041392
-
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
-
Flores E.R., Tsai K.Y., Crowley D., Sengupta S., Yang A., McKeon F., and Jacks T. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature 416 (2002) 560-564
-
(2002)
Nature
, vol.416
, pp. 560-564
-
-
Flores, E.R.1
Tsai, K.Y.2
Crowley, D.3
Sengupta, S.4
Yang, A.5
McKeon, F.6
Jacks, T.7
-
25
-
-
0037930098
-
p63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome
-
Fomenkov A., Huang Y.P., Topaloglu O., Brechman A., Osada M., Fomenkova T., Yuriditsky E., Trink B., Sidransky D., and Ratovitski E. p63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome. J Biol Chem 278 (2003) 23906-23914
-
(2003)
J Biol Chem
, vol.278
, pp. 23906-23914
-
-
Fomenkov, A.1
Huang, Y.P.2
Topaloglu, O.3
Brechman, A.4
Osada, M.5
Fomenkova, T.6
Yuriditsky, E.7
Trink, B.8
Sidransky, D.9
Ratovitski, E.10
-
26
-
-
0037011673
-
Tumour stage, node stage, p53 gene status, and bcl-2 protein expression as predictors of tumour response to platin-fluorouracil chemotherapy in patients with squamous-cell carcinoma of the head and neck
-
Fouret P., Temam S., Charlotte F., and Lacau-St-Guily J. Tumour stage, node stage, p53 gene status, and bcl-2 protein expression as predictors of tumour response to platin-fluorouracil chemotherapy in patients with squamous-cell carcinoma of the head and neck. Br J Cancer 87 (2002) 1390-1395
-
(2002)
Br J Cancer
, vol.87
, pp. 1390-1395
-
-
Fouret, P.1
Temam, S.2
Charlotte, F.3
Lacau-St-Guily, J.4
-
27
-
-
0032971947
-
Expression of apoptosis-related genes in human head and neck squamous cell carcinomas undergoing p53-mediated programmed cell death
-
Frederick M.J., Holton P.R., Hudson M., Wang M., and Clayman G.L. Expression of apoptosis-related genes in human head and neck squamous cell carcinomas undergoing p53-mediated programmed cell death. Clin Cancer Res 5 (1999) 361-369
-
(1999)
Clin Cancer Res
, vol.5
, pp. 361-369
-
-
Frederick, M.J.1
Holton, P.R.2
Hudson, M.3
Wang, M.4
Clayman, G.L.5
-
28
-
-
0034600339
-
Evidence for a causal association between human papillomavirus and a subset of head and neck cancers
-
Gillison M.L., Koch W.M., Capone R.B., Spafford M., Westra W.H., Wu L., Zahurak M.L., Daniel R.W., Viglione M., Symer D.E., Shah K.V., and Sidransky D. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst 92 (2000) 709-720
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 709-720
-
-
Gillison, M.L.1
Koch, W.M.2
Capone, R.B.3
Spafford, M.4
Westra, W.H.5
Wu, L.6
Zahurak, M.L.7
Daniel, R.W.8
Viglione, M.9
Symer, D.E.10
Shah, K.V.11
Sidransky, D.12
-
29
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis
-
Greenblatt M.S., Bennett W.P., Hollstein M., and Haris C.C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54 (1994) 4855-4878
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Haris, C.C.4
-
30
-
-
0037317521
-
The role of p53 in determining sensitivity to radiotherapy
-
Gudkov A.V., and Komarova E.A. The role of p53 in determining sensitivity to radiotherapy. Nat Rev Cancer 3 (2003) 117-129
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 117-129
-
-
Gudkov, A.V.1
Komarova, E.A.2
-
31
-
-
0142122353
-
A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5-8
-
Hafkamp H.C., Speel E.J., Haesevoets A., Bot F.J., Dinjens W.N., Ramaekers F.C., Hopman A.H., and Manni J.J. A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5-8. Int J Cancer 107 (2003) 394-400
-
(2003)
Int J Cancer
, vol.107
, pp. 394-400
-
-
Hafkamp, H.C.1
Speel, E.J.2
Haesevoets, A.3
Bot, F.J.4
Dinjens, W.N.5
Ramaekers, F.C.6
Hopman, A.H.7
Manni, J.J.8
-
32
-
-
0028299342
-
p53 in tumour pathology: can we trust immunohistochemistry? - Revisited!
-
Hall P.A., and Lane D.P. p53 in tumour pathology: can we trust immunohistochemistry? - Revisited!. J Pathol 172 (1994) 1-4
-
(1994)
J Pathol
, vol.172
, pp. 1-4
-
-
Hall, P.A.1
Lane, D.P.2
-
33
-
-
1842531115
-
Real-time gap ligase chain reaction: a rapid semi-quantitative assay for detecting p53 mutation at low levels in surgical margins and lymph nodes from resected lung and head and neck tumors
-
Harden S.V., Thomas D.C., Benoit N., Minhas K., Westra W.H., Califano J.A., Koch W., and Sidransky D. Real-time gap ligase chain reaction: a rapid semi-quantitative assay for detecting p53 mutation at low levels in surgical margins and lymph nodes from resected lung and head and neck tumors. Clin Cancer Res 10 (2004) 2379-2385
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2379-2385
-
-
Harden, S.V.1
Thomas, D.C.2
Benoit, N.3
Minhas, K.4
Westra, W.H.5
Califano, J.A.6
Koch, W.7
Sidransky, D.8
-
34
-
-
0142030167
-
Chapter 7: Human papillomavirus and cancer of the upper aerodigestive tract
-
Herrero R. Chapter 7: Human papillomavirus and cancer of the upper aerodigestive tract. J Natl Cancer Inst Monogr 31 (2003) 47-51
-
(2003)
J Natl Cancer Inst Monogr
, vol.31
, pp. 47-51
-
-
Herrero, R.1
-
35
-
-
0034625043
-
AIS is an oncogene amplified in squamous cell carcinoma
-
Hibi K., Trink B., Patturajan M., Westra W.H., Caballero O.L., Hill D.E., Ratovitski E.A., Jen J., and Sidransky D. AIS is an oncogene amplified in squamous cell carcinoma. Proc Natl Acad Sci USA 97 (2000) 5462-5467
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5462-5467
-
-
Hibi, K.1
Trink, B.2
Patturajan, M.3
Westra, W.H.4
Caballero, O.L.5
Hill, D.E.6
Ratovitski, E.A.7
Jen, J.8
Sidransky, D.9
-
36
-
-
4243165543
-
Genes involved in stem cell fate decisions and commitment to differentiation play a role in skin disease
-
Honeycutt K.A., Koster M.I., and Roop D.R. Genes involved in stem cell fate decisions and commitment to differentiation play a role in skin disease. J Investig Dermatol Symp Proc 9 (2004) 261-268
-
(2004)
J Investig Dermatol Symp Proc
, vol.9
, pp. 261-268
-
-
Honeycutt, K.A.1
Koster, M.I.2
Roop, D.R.3
-
37
-
-
27144529920
-
The role of p53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma
-
Hong Y., Miao X., Zhang X., Ding F., Luo A., Guo Y., Tan W., Liu Z., and Lin D. The role of p53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma. Cancer Res 65 (2005) 9582-9587
-
(2005)
Cancer Res
, vol.65
, pp. 9582-9587
-
-
Hong, Y.1
Miao, X.2
Zhang, X.3
Ding, F.4
Luo, A.5
Guo, Y.6
Tan, W.7
Liu, Z.8
Lin, D.9
-
38
-
-
0037146761
-
Elevated expression of p63 protein in human esophageal squamous cell carcinomas
-
Hu H., Xia S.H., Li A.D., Xu X., Cai Y., Han Y.L., Wei F., Chen B.S., Huang X.P., Han Y.S., Zhang J.W., Zhang X., Wu M., and Wang M.R. Elevated expression of p63 protein in human esophageal squamous cell carcinomas. Int J Cancer 102 (2002) 580-583
-
(2002)
Int J Cancer
, vol.102
, pp. 580-583
-
-
Hu, H.1
Xia, S.H.2
Li, A.D.3
Xu, X.4
Cai, Y.5
Han, Y.L.6
Wei, F.7
Chen, B.S.8
Huang, X.P.9
Han, Y.S.10
Zhang, J.W.11
Zhang, X.12
Wu, M.13
Wang, M.R.14
-
39
-
-
2542422438
-
Structure and processing of cisplatin-DNA adducts
-
Jamieson E.R., and Lippard S.J. Structure and processing of cisplatin-DNA adducts. Chem Rev 98 (1999) 2467-2498
-
(1999)
Chem Rev
, vol.98
, pp. 2467-2498
-
-
Jamieson, E.R.1
Lippard, S.J.2
-
40
-
-
0028952841
-
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms
-
Jeffrey P.D., Gorina S., and Pavletich N.P. Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms. Science 267 (1995) 1498-1502
-
(1995)
Science
, vol.267
, pp. 1498-1502
-
-
Jeffrey, P.D.1
Gorina, S.2
Pavletich, N.P.3
-
41
-
-
0031564954
-
p73 is a simian [correction of human] p53-related protein that can induce apoptosis
-
Jost C.A., Marin M.C., and Kaelin Jr. W.G. p73 is a simian [correction of human] p53-related protein that can induce apoptosis. Nature 389 (1997) 191-194
-
(1997)
Nature
, vol.389
, pp. 191-194
-
-
Jost, C.A.1
Marin, M.C.2
Kaelin Jr., W.G.3
-
42
-
-
0033552641
-
The p53 gene family
-
Kaelin W.G. The p53 gene family. Oncogene 18 (1999) 7701-7715
-
(1999)
Oncogene
, vol.18
, pp. 7701-7715
-
-
Kaelin, W.G.1
-
43
-
-
0030812331
-
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
-
Kaghad M., Bonnet H., Yang A., Creancier L., Biscan J.C., Valent A., Minty A., Chalon P., Lelias J.M., Dumont X., Ferrara P., McKeon F., and Caput D. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 90 (1997) 809-819
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
Creancier, L.4
Biscan, J.C.5
Valent, A.6
Minty, A.7
Chalon, P.8
Lelias, J.M.9
Dumont, X.10
Ferrara, P.11
McKeon, F.12
Caput, D.13
-
44
-
-
0033831080
-
A controlled trial of intratumoural ONYX-015 a selectively-replicating adenovirus in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri F.R., Nemunaitis J., Ganly I., Arseneau J., Tannock I.F., Romel L., Gore M., Ironside J., MacDougall R.H., Heise C., Randlev B., Gillenwater A.M., Bruso P., Kaye S.B., Hong W.K., and Kirn D.H. A controlled trial of intratumoural ONYX-015 a selectively-replicating adenovirus in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 6 (2000) 879-885
-
(2000)
Nat Med
, vol.6
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
Arseneau, J.4
Tannock, I.F.5
Romel, L.6
Gore, M.7
Ironside, J.8
MacDougall, R.H.9
Heise, C.10
Randlev, B.11
Gillenwater, A.M.12
Bruso, P.13
Kaye, S.B.14
Hong, W.K.15
Kirn, D.H.16
-
45
-
-
0032833964
-
Head and neck cancer in nonsmokers: a distinct clinical and molecular entity
-
Koch W.M., Lango M., Sewell D., Zahurak M., and Sidransky D. Head and neck cancer in nonsmokers: a distinct clinical and molecular entity. Laryngoscope 109 (1999) 1544-1551
-
(1999)
Laryngoscope
, vol.109
, pp. 1544-1551
-
-
Koch, W.M.1
Lango, M.2
Sewell, D.3
Zahurak, M.4
Sidransky, D.5
-
46
-
-
0035884487
-
Chemoprotection from p53-dependent apoptosis: potential clinical applications of the p53 inhibitors
-
Komarova E.A., and Gudkov A.V. Chemoprotection from p53-dependent apoptosis: potential clinical applications of the p53 inhibitors. Biochem Pharmacol 62 (2001) 657-667
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 657-667
-
-
Komarova, E.A.1
Gudkov, A.V.2
-
47
-
-
12244266670
-
Epidermal differentiation: transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation
-
Koster M., Huntzinger K.A., and Roop D.R. Epidermal differentiation: transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation. J Invest Dermatol Symp Proc 7 (2002) 41-45
-
(2002)
J Invest Dermatol Symp Proc
, vol.7
, pp. 41-45
-
-
Koster, M.1
Huntzinger, K.A.2
Roop, D.R.3
-
48
-
-
0026480247
-
Carcinogen-specific mutational pattern in the p53 gene in ultraviolet B radiation-induced squamous cell carcinomas of mouse skin
-
Kress S., Sutter C., Strickland P.T., Mukhtar H., Schweizer J., and Schwarz M. Carcinogen-specific mutational pattern in the p53 gene in ultraviolet B radiation-induced squamous cell carcinomas of mouse skin. Cancer Res 52 (1992) 6400-6413
-
(1992)
Cancer Res
, vol.52
, pp. 6400-6413
-
-
Kress, S.1
Sutter, C.2
Strickland, P.T.3
Mukhtar, H.4
Schweizer, J.5
Schwarz, M.6
-
49
-
-
0032922061
-
Sequencing analysis of RNA and DNA of exons 1 through 11 shows p53 gene alterations to be present in almost 100% of head and neck squamous cell cancers
-
Kropveld A., Rozemuller E.H., Leppers F.G., Scheidel K.C., de Weger R.A., Koole R., Hordijk G.J., Slootweg P.J., and Tilanus M.G. Sequencing analysis of RNA and DNA of exons 1 through 11 shows p53 gene alterations to be present in almost 100% of head and neck squamous cell cancers. Lab Invest 79 (1999) 347-353
-
(1999)
Lab Invest
, vol.79
, pp. 347-353
-
-
Kropveld, A.1
Rozemuller, E.H.2
Leppers, F.G.3
Scheidel, K.C.4
de Weger, R.A.5
Koole, R.6
Hordijk, G.J.7
Slootweg, P.J.8
Tilanus, M.G.9
-
50
-
-
0027109075
-
Cancer. p53, guardian of the genome
-
Lane D.P. Cancer. p53, guardian of the genome. Nature 358 (1992) 15-16
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
52
-
-
24344502263
-
Butyrate response factor 1 enhances cisplatin sensitivity in human head and neck squamous cell carcinoma cell lines
-
Lee S.K., Kim S.B., Kim J.S., Moon C.H., Han M.S., Lee B.J., Chung D.K., Min Y.J., Park J.H., Choi D.H., Cho H.R., Park S.K., and Park J.W. Butyrate response factor 1 enhances cisplatin sensitivity in human head and neck squamous cell carcinoma cell lines. Int J Cancer 117 (2005) 32-40
-
(2005)
Int J Cancer
, vol.117
, pp. 32-40
-
-
Lee, S.K.1
Kim, S.B.2
Kim, J.S.3
Moon, C.H.4
Han, M.S.5
Lee, B.J.6
Chung, D.K.7
Min, Y.J.8
Park, J.H.9
Choi, D.H.10
Cho, H.R.11
Park, S.K.12
Park, J.W.13
-
53
-
-
33645237256
-
Refined characterization of head and neck squamous cell carcinomas expressing a seemingly wild-type p53 protein
-
Leng K., Schlien S., and Bosch F.X. Refined characterization of head and neck squamous cell carcinomas expressing a seemingly wild-type p53 protein. J Oral Pathol Med 35 (2006) 19-24
-
(2006)
J Oral Pathol Med
, vol.35
, pp. 19-24
-
-
Leng, K.1
Schlien, S.2
Bosch, F.X.3
-
54
-
-
0035956215
-
The human papillomavirus E6 protein and its contribution to malignant progression
-
Mantovani F., and Banks L. The human papillomavirus E6 protein and its contribution to malignant progression. Oncogene 20 (2001) 7874-7887
-
(2001)
Oncogene
, vol.20
, pp. 7874-7887
-
-
Mantovani, F.1
Banks, L.2
-
55
-
-
0034063604
-
A common polymorphism acts as an intragenic modifier of mutant p53 behaviour
-
Marin M.C., Jost C.A., Brooks L.A., Irwin M.S., O'Nions J., Tidy J.A., James N., McGregor J.M., Harwood C.A., Yulug I.G., Vousden K.H., Allday M.J., Gusterson B., Ikawa S., Hinds P.W., Crook T., and Kaelin W.G. A common polymorphism acts as an intragenic modifier of mutant p53 behaviour. Nat Genet 25 (2000) 47-54
-
(2000)
Nat Genet
, vol.25
, pp. 47-54
-
-
Marin, M.C.1
Jost, C.A.2
Brooks, L.A.3
Irwin, M.S.4
O'Nions, J.5
Tidy, J.A.6
James, N.7
McGregor, J.M.8
Harwood, C.A.9
Yulug, I.G.10
Vousden, K.H.11
Allday, M.J.12
Gusterson, B.13
Ikawa, S.14
Hinds, P.W.15
Crook, T.16
Kaelin, W.G.17
-
56
-
-
0037069330
-
Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways
-
Martinez L.A., Naguibneva I., Lehrmann H., Vervisch A., Tchénio T., Lozano G., and Harel-Bellan A. Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways. Proc Natl Acad Sci USA 99 (2002) 14849-14854
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14849-14854
-
-
Martinez, L.A.1
Naguibneva, I.2
Lehrmann, H.3
Vervisch, A.4
Tchénio, T.5
Lozano, G.6
Harel-Bellan, A.7
-
57
-
-
25444521768
-
A strategy for defining biologically relevant levels of p53 protein expression in clinical samples with reference to endometrial neoplasia
-
McCluggage W.G., Connolly L.E., McGregor G., Hyland P.L., and Hall P.A. A strategy for defining biologically relevant levels of p53 protein expression in clinical samples with reference to endometrial neoplasia. Int J Gynecol Pathol 24 (2005) 307-312
-
(2005)
Int J Gynecol Pathol
, vol.24
, pp. 307-312
-
-
McCluggage, W.G.1
Connolly, L.E.2
McGregor, G.3
Hyland, P.L.4
Hall, P.A.5
-
58
-
-
0032576632
-
p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases
-
Medema R.H., Klompmaker R., Smits V.A., and Rijksen G. p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases. Oncogene 16 (1998) 431-441
-
(1998)
Oncogene
, vol.16
, pp. 431-441
-
-
Medema, R.H.1
Klompmaker, R.2
Smits, V.A.3
Rijksen, G.4
-
59
-
-
1542379662
-
p73 induces apoptosis via PUMA transactivation and Bax mitochondrial translocation
-
Melino G., Bernassola F., Ranalli M., Yee K., Zong W.X., Corazzari M., Knight R.A., Green D.R., Thompson C., and Vousden K.H. p73 induces apoptosis via PUMA transactivation and Bax mitochondrial translocation. J Biol Chem 279 (2004) 8076-8083
-
(2004)
J Biol Chem
, vol.279
, pp. 8076-8083
-
-
Melino, G.1
Bernassola, F.2
Ranalli, M.3
Yee, K.4
Zong, W.X.5
Corazzari, M.6
Knight, R.A.7
Green, D.R.8
Thompson, C.9
Vousden, K.H.10
-
60
-
-
1342305505
-
p73, the 'assistant' guardian of the genome?
-
Melino G. p73, the 'assistant' guardian of the genome?. Ann N Y Acad Sci 1010 (2003) 9-15
-
(2003)
Ann N Y Acad Sci
, vol.1010
, pp. 9-15
-
-
Melino, G.1
-
61
-
-
3543110350
-
p63 and p73: roles in development and tumor formation
-
Moll U.M., and Slade N. p63 and p73: roles in development and tumor formation. Mol Cancer Res 2 (2004) 371-386
-
(2004)
Mol Cancer Res
, vol.2
, pp. 371-386
-
-
Moll, U.M.1
Slade, N.2
-
62
-
-
3042770838
-
The dl1520 virus is found preferentially in tumor tissue after direct intratumoral injection in oral carcinoma
-
Morley S., MacDonald G., Kirn D., Kaye S., Brown R., and Soutar D. The dl1520 virus is found preferentially in tumor tissue after direct intratumoral injection in oral carcinoma. Clin Cancer Res 10 (2004) 4357-4362
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4357-4362
-
-
Morley, S.1
MacDonald, G.2
Kirn, D.3
Kaye, S.4
Brown, R.5
Soutar, D.6
-
63
-
-
0035863458
-
Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer
-
Nemunaitis J., Khuri F., Ganly I., Arseneau J., Posner M., Vokes E., Kuhn J., McCarty T., Landers S., Blackburn A., Romel L., Randlev B., Kaye S., and Kirn D. Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer. J Clin Oncol 19 (2001) 289-298
-
(2001)
J Clin Oncol
, vol.19
, pp. 289-298
-
-
Nemunaitis, J.1
Khuri, F.2
Ganly, I.3
Arseneau, J.4
Posner, M.5
Vokes, E.6
Kuhn, J.7
McCarty, T.8
Landers, S.9
Blackburn, A.10
Romel, L.11
Randlev, B.12
Kaye, S.13
Kirn, D.14
-
64
-
-
0033950285
-
Adenovirus -mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer
-
Nemunaitis J., Swisher S.G., Timmons T., Connors D., Mack M., Doerksen L., Weill D., Wait J., Lawrence D.D., Kemp B.L., Fossella F., Glisson B.S., Hong W.K., Khuri F.R., Kurie J.M., Lee J.J., Lee J.S., Nguyen D.M., Nesbitt J.C., Perez-Soler R., Pisters K.M., Putnam J.B., Richli W.R., Shin D.M., Walsh G.L., Merritt J., and Roth J. Adenovirus -mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer. J Clin Oncol 18 (2000) 609-622
-
(2000)
J Clin Oncol
, vol.18
, pp. 609-622
-
-
Nemunaitis, J.1
Swisher, S.G.2
Timmons, T.3
Connors, D.4
Mack, M.5
Doerksen, L.6
Weill, D.7
Wait, J.8
Lawrence, D.D.9
Kemp, B.L.10
Fossella, F.11
Glisson, B.S.12
Hong, W.K.13
Khuri, F.R.14
Kurie, J.M.15
Lee, J.J.16
Lee, J.S.17
Nguyen, D.M.18
Nesbitt, J.C.19
Perez-Soler, R.20
Pisters, K.M.21
Putnam, J.B.22
Richli, W.R.23
Shin, D.M.24
Walsh, G.L.25
Merritt, J.26
Roth, J.27
more..
-
65
-
-
27644590943
-
Discriminating functional and non-functional p53 in human tumours by immunohistochemistry
-
Nenutil R., Smardova J., Pavlova S., Hanzelkova Z., Muller P., Fabian P., Hrstka R., Janotova P., Radina M., Lane D.P., Coates P.J., and Vojtesek B. Discriminating functional and non-functional p53 in human tumours by immunohistochemistry. J Pathol 207 (2005) 251-259
-
(2005)
J Pathol
, vol.207
, pp. 251-259
-
-
Nenutil, R.1
Smardova, J.2
Pavlova, S.3
Hanzelkova, Z.4
Muller, P.5
Fabian, P.6
Hrstka, R.7
Janotova, P.8
Radina, M.9
Lane, D.P.10
Coates, P.J.11
Vojtesek, B.12
-
66
-
-
0028953618
-
p53 mutations, protein expression and cell proliferation in squamous cell carcinomas of the head and neck
-
Nylander K., Nilsson P., Mehle C., and Roos G. p53 mutations, protein expression and cell proliferation in squamous cell carcinomas of the head and neck. Br J Cancer 71 (1995) 826-830
-
(1995)
Br J Cancer
, vol.71
, pp. 826-830
-
-
Nylander, K.1
Nilsson, P.2
Mehle, C.3
Roos, G.4
-
67
-
-
0036278655
-
A preclinical model of minimal residual cancer in the muscle highlights challenges associated with adenovirus-mediated p53 gene transfer
-
Oakley R., Phillips E., Hooper R., Wilson D., and Partridge M. A preclinical model of minimal residual cancer in the muscle highlights challenges associated with adenovirus-mediated p53 gene transfer. Clin Cancer Res 8 (2002) 1984-1994
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1984-1994
-
-
Oakley, R.1
Phillips, E.2
Hooper, R.3
Wilson, D.4
Partridge, M.5
-
68
-
-
19944363519
-
Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumour selectivity
-
O'Shea C.C., Johnson L., Bagus B., Choi S., Nicholas C., Shen A., Boyle L., Pandey K., Soria C., Kunich J., Shen Y., Habets G., Ginzinger D., and McCormick F. Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumour selectivity. Cancer Cell 6 (2004) 611-623
-
(2004)
Cancer Cell
, vol.6
, pp. 611-623
-
-
O'Shea, C.C.1
Johnson, L.2
Bagus, B.3
Choi, S.4
Nicholas, C.5
Shen, A.6
Boyle, L.7
Pandey, K.8
Soria, C.9
Kunich, J.10
Shen, Y.11
Habets, G.12
Ginzinger, D.13
McCormick, F.14
-
69
-
-
0031406675
-
Field cancerisation of the oral cavity: comparison of the spectrum of molecular alterations in cases presenting with both dysplastic and malignant lesions
-
Partridge M., Emilion G., Pateromichelakis S., Phillips E., and Langdon J. Field cancerisation of the oral cavity: comparison of the spectrum of molecular alterations in cases presenting with both dysplastic and malignant lesions. Eur J Cancer Oral Oncol 33 (1997) 332-337
-
(1997)
Eur J Cancer Oral Oncol
, vol.33
, pp. 332-337
-
-
Partridge, M.1
Emilion, G.2
Pateromichelakis, S.3
Phillips, E.4
Langdon, J.5
-
70
-
-
0032033747
-
Allelic imbalance at chromosomal loci implicated in the pathogenesis of oral precancer, cumulative loss and its relationship with progression to cancer
-
Partridge M., Emilion G., Pateromichelakis S., A'Hern R., Phillips E., and Langdon J. Allelic imbalance at chromosomal loci implicated in the pathogenesis of oral precancer, cumulative loss and its relationship with progression to cancer. Eur J Cancer Oral Oncol 34 (1998) 77-83
-
(1998)
Eur J Cancer Oral Oncol
, vol.34
, pp. 77-83
-
-
Partridge, M.1
Emilion, G.2
Pateromichelakis, S.3
A'Hern, R.4
Phillips, E.5
Langdon, J.6
-
71
-
-
0033001484
-
The prognostic significance of allelic imbalance at key chromosomal loci in oral cancer
-
Partridge M., Emilion G., Pateromichelakis S., A'Hern R., Lee G., Phillips E., and Langdon J. The prognostic significance of allelic imbalance at key chromosomal loci in oral cancer. Br J Cancer 79 (1999) 1821-1827
-
(1999)
Br J Cancer
, vol.79
, pp. 1821-1827
-
-
Partridge, M.1
Emilion, G.2
Pateromichelakis, S.3
A'Hern, R.4
Lee, G.5
Phillips, E.6
Langdon, J.7
-
72
-
-
0032993564
-
Patient-specific mutation databases for oral cancer
-
Partridge M., Emilion G., Falworth M., A'Hern R., Phillips E., Pateromichelakis S., and Langdon J. Patient-specific mutation databases for oral cancer. Int J Cancer 84 (1999) 284-292
-
(1999)
Int J Cancer
, vol.84
, pp. 284-292
-
-
Partridge, M.1
Emilion, G.2
Falworth, M.3
A'Hern, R.4
Phillips, E.5
Pateromichelakis, S.6
Langdon, J.7
-
73
-
-
0032890030
-
New insights into p53 protein stabilisation in oral squamous cell carcinoma
-
Partridge M., Kiguwa S., Emilion G., Pateromichelakis S., A'Hern R., and Langdon J.D. New insights into p53 protein stabilisation in oral squamous cell carcinoma. Eur J Cancer 35 (1999) 45-55
-
(1999)
Eur J Cancer
, vol.35
, pp. 45-55
-
-
Partridge, M.1
Kiguwa, S.2
Emilion, G.3
Pateromichelakis, S.4
A'Hern, R.5
Langdon, J.D.6
-
74
-
-
0033939967
-
Detection of minimal residual cancer to investigate why oral tumours recur despite seemingly adequate treatment
-
Partridge M., Li S.-R., Pateromichelakis S., Francis R.A., Phillips E., Huang X.-H., Tesfa-Selase F., and Langdon J.D. Detection of minimal residual cancer to investigate why oral tumours recur despite seemingly adequate treatment. Clin Cancer Res 6 (2000) 2718-2725
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2718-2725
-
-
Partridge, M.1
Li, S.-R.2
Pateromichelakis, S.3
Francis, R.A.4
Phillips, E.5
Huang, X.-H.6
Tesfa-Selase, F.7
Langdon, J.D.8
-
75
-
-
0034660881
-
A case-control study confirms that microsatellite assay can identify patients at risk of developing oral SCC within a field of cancerisation
-
Partridge M., Pateromichelakis S., Phillips E., Emilion G.G., A'Hern R.P., and Langdon J.D. A case-control study confirms that microsatellite assay can identify patients at risk of developing oral SCC within a field of cancerisation. Cancer Res 60 (2000) 3893-3898
-
(2000)
Cancer Res
, vol.60
, pp. 3893-3898
-
-
Partridge, M.1
Pateromichelakis, S.2
Phillips, E.3
Emilion, G.G.4
A'Hern, R.P.5
Langdon, J.D.6
-
78
-
-
0142089747
-
Fatal systemic inflammatory response in an ornithine transcarbamylase deficient patient following adenoviral gene transfer
-
Raper S.E., Chirmule N., Lee F.S., Wivel N.A., Bagg A., Gao G.P., Wilson J.M., and Batshaw M.L. Fatal systemic inflammatory response in an ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol Genet Metab 80 (2003) 148-158
-
(2003)
Mol Genet Metab
, vol.80
, pp. 148-158
-
-
Raper, S.E.1
Chirmule, N.2
Lee, F.S.3
Wivel, N.A.4
Bagg, A.5
Gao, G.P.6
Wilson, J.M.7
Batshaw, M.L.8
-
79
-
-
0035852688
-
p53 associates with and targets Np63 into a protein degradation pathway
-
Ratovitski E.A., Patturajan M., Hibi K., Trink B., Yamaguchi K., and Sidransky D. p53 associates with and targets Np63 into a protein degradation pathway. Proc Natl Acad Sci USA 98 (2001) 1817-1822
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1817-1822
-
-
Ratovitski, E.A.1
Patturajan, M.2
Hibi, K.3
Trink, B.4
Yamaguchi, K.5
Sidransky, D.6
-
80
-
-
22944476168
-
Effects of ONYX-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin
-
Reid T.R., Freeman S., Post L., McCormick F., and Sze D.Y. Effects of ONYX-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin. Cancer Gene Ther 12 (2005) 673-681
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 673-681
-
-
Reid, T.R.1
Freeman, S.2
Post, L.3
McCormick, F.4
Sze, D.Y.5
-
81
-
-
0035236713
-
Sensitive detection of p53 mutation: analysis by direct sequencing and multisequence analysis
-
Rozemuller E.H., Kropveld A., Kreyveld E., Leppers F.G., and Scheidel K. Sensitive detection of p53 mutation: analysis by direct sequencing and multisequence analysis. Cancer Detect Prev 25 (2001) 109-116
-
(2001)
Cancer Detect Prev
, vol.25
, pp. 109-116
-
-
Rozemuller, E.H.1
Kropveld, A.2
Kreyveld, E.3
Leppers, F.G.4
Scheidel, K.5
-
82
-
-
30344450404
-
p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis
-
Rocco J.W., Leong C.-O., Kuperwasser N., DeYoung M.P., and Ellison L.W. p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis. Cancer Cell 9 (2006) 45-56
-
(2006)
Cancer Cell
, vol.9
, pp. 45-56
-
-
Rocco, J.W.1
Leong, C.-O.2
Kuperwasser, N.3
DeYoung, M.P.4
Ellison, L.W.5
-
83
-
-
0034161976
-
In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy
-
Rogulski K.R., Freytag S.O., Zhang K., Gilbert J.D., Paielli D.L., Kim J.H., Heise C.C., and Kirn D.H. In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy. Cancer Res 60 (2000) 1193-1196
-
(2000)
Cancer Res
, vol.60
, pp. 1193-1196
-
-
Rogulski, K.R.1
Freytag, S.O.2
Zhang, K.3
Gilbert, J.D.4
Paielli, D.L.5
Kim, J.H.6
Heise, C.C.7
Kirn, D.H.8
-
84
-
-
0033975644
-
Use of allelic loss to predict malignant risk for low-grade oral epithelial dysplasia
-
Rosin M.P., Cheng X., Poh C.F., Lam W.L., Huang Y., Lovas J., Berean K., Epstein J.B., Priddy R., Le N.D., and Zhang L. Use of allelic loss to predict malignant risk for low-grade oral epithelial dysplasia. Clin Cancer Res 6 (2000) 357-362
-
(2000)
Clin Cancer Res
, vol.6
, pp. 357-362
-
-
Rosin, M.P.1
Cheng, X.2
Poh, C.F.3
Lam, W.L.4
Huang, Y.5
Lovas, J.6
Berean, K.7
Epstein, J.B.8
Priddy, R.9
Le, N.D.10
Zhang, L.11
-
85
-
-
1542438707
-
An attenuated adenovirus ONYX-015 as mouthwash therapy for premalignant oral dysplasia
-
Rudin C.M., Cohen E.E.W., and Papadimitrakopoulou V.A. An attenuated adenovirus ONYX-015 as mouthwash therapy for premalignant oral dysplasia. J Clin Oncol 21 (2003) 4546-4552
-
(2003)
J Clin Oncol
, vol.21
, pp. 4546-4552
-
-
Rudin, C.M.1
Cohen, E.E.W.2
Papadimitrakopoulou, V.A.3
-
86
-
-
17944379798
-
ASPP proteins specifically stimulate the apoptotic function of p53
-
Samuels-Lev Y., O'Connor D.J., Bergamaschi D., Trigiante G., Hsieh J.K., Zhong S., Campargue I., Naumovski, Crook T., and Lu X. ASPP proteins specifically stimulate the apoptotic function of p53. Mol Cell 8 (2001) 781-794
-
(2001)
Mol Cell
, vol.8
, pp. 781-794
-
-
Samuels-Lev, Y.1
O'Connor, D.J.2
Bergamaschi, D.3
Trigiante, G.4
Hsieh, J.K.5
Zhong, S.6
Campargue, I.7
Naumovski8
Crook, T.9
Lu, X.10
-
87
-
-
0030884751
-
A novel protein with strong homology to the tumor suppressor p53
-
Schmale H., and Bamberger C. A novel protein with strong homology to the tumor suppressor p53. Oncogene 15 (1997) 1363-1367
-
(1997)
Oncogene
, vol.15
, pp. 1363-1367
-
-
Schmale, H.1
Bamberger, C.2
-
88
-
-
0032522463
-
p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha
-
Sheikh M.S., Burns T.F., Huang Y., Wu G.S., Amundson S., Brooks K.S., Fornace A.J., and el-Deiry W.S. p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha. Cancer Res 58 (1998) 1593-1598
-
(1998)
Cancer Res
, vol.58
, pp. 1593-1598
-
-
Sheikh, M.S.1
Burns, T.F.2
Huang, Y.3
Wu, G.S.4
Amundson, S.5
Brooks, K.S.6
Fornace, A.J.7
el-Deiry, W.S.8
-
89
-
-
0030934160
-
Comparison of p53 immunoreactivity in fresh-cut versus stored slides with and without microwave heating
-
Shin H.J., Kalapurakal S.K., Lee J.J., Ro J.Y., Hong W.K., and Lee J.S. Comparison of p53 immunoreactivity in fresh-cut versus stored slides with and without microwave heating. Mod Pathol 10 (1997) 224-230
-
(1997)
Mod Pathol
, vol.10
, pp. 224-230
-
-
Shin, H.J.1
Kalapurakal, S.K.2
Lee, J.J.3
Ro, J.Y.4
Hong, W.K.5
Lee, J.S.6
-
90
-
-
10044266819
-
Dominant Negative p63 Isoform Expression in Head and Neck Squamous Cell Carcinoma
-
Sniezek J.C., Matheny K.E., Westfall M.D., and Pietenpol J.A. Dominant Negative p63 Isoform Expression in Head and Neck Squamous Cell Carcinoma. Laryngoscope 114 (2004) 2063-2072
-
(2004)
Laryngoscope
, vol.114
, pp. 2063-2072
-
-
Sniezek, J.C.1
Matheny, K.E.2
Westfall, M.D.3
Pietenpol, J.A.4
-
91
-
-
29744446941
-
Meta-analysis of the p53 mutation database for mutant p53 biological activity reveals a methodologic bias in mutation detection
-
Soussi T., Asselain B., Hamroun D., Kato S., Ishioka C., Claustres M., and Beroud C. Meta-analysis of the p53 mutation database for mutant p53 biological activity reveals a methodologic bias in mutation detection. Clin Cancer Res 12 (2006) 62-69
-
(2006)
Clin Cancer Res
, vol.12
, pp. 62-69
-
-
Soussi, T.1
Asselain, B.2
Hamroun, D.3
Kato, S.4
Ishioka, C.5
Claustres, M.6
Beroud, C.7
-
92
-
-
2442689078
-
Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo
-
Sullivan A., Syed N., Gasco M., Bergamaschi D., Trigiante G., Attard M., Hiller L., Farrell P.J., Smith P., Lu X., and Crook T. Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo. Oncogene 23 (2004) 3328-3337
-
(2004)
Oncogene
, vol.23
, pp. 3328-3337
-
-
Sullivan, A.1
Syed, N.2
Gasco, M.3
Bergamaschi, D.4
Trigiante, G.5
Attard, M.6
Hiller, L.7
Farrell, P.J.8
Smith, P.9
Lu, X.10
Crook, T.11
-
93
-
-
1242316989
-
STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis
-
Townsend P.A., Scarabelli T.M., Davidson S.M., Knight R.A., Latchman D.S., and Stephanou A. STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis. J Biol Chem 279 (2004) 5811-5820
-
(2004)
J Biol Chem
, vol.279
, pp. 5811-5820
-
-
Townsend, P.A.1
Scarabelli, T.M.2
Davidson, S.M.3
Knight, R.A.4
Latchman, D.S.5
Stephanou, A.6
-
94
-
-
2542570373
-
Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study
-
van Houten V.M., Leemans C.R., Kummer J.A., Dijkstra J., Kuik D.J., van den Brekel M.W., Snow G.B., and Brakenhoff R.H. Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study. Clin Cancer Res 10 (2004) 3614-3620
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3614-3620
-
-
van Houten, V.M.1
Leemans, C.R.2
Kummer, J.A.3
Dijkstra, J.4
Kuik, D.J.5
van den Brekel, M.W.6
Snow, G.B.7
Brakenhoff, R.H.8
-
95
-
-
0035879829
-
Biological evidence that human papillomaviruses are etiologically involved in a subgroup of head and neck squamous cell carcinomas
-
van Houten V.M., Snijders P.J., van den Brekel M.W., Kummer J.A., Meijer C.J., van Leeuwen B., Denkers F., Smeele L.E., Snow G.B., and Brakenhoff R.H. Biological evidence that human papillomaviruses are etiologically involved in a subgroup of head and neck squamous cell carcinomas. Int J Cancer 93 (2001) 232-235
-
(2001)
Int J Cancer
, vol.93
, pp. 232-235
-
-
van Houten, V.M.1
Snijders, P.J.2
van den Brekel, M.W.3
Kummer, J.A.4
Meijer, C.J.5
van Leeuwen, B.6
Denkers, F.7
Smeele, L.E.8
Snow, G.B.9
Brakenhoff, R.H.10
-
96
-
-
0037087621
-
Phase I trial of intraperitoneal injection of the E1B-55-kD-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer
-
Vasey P.A., Shulman L.N., Campos S., Davis J., Gore M., Johnston S., Kirn D.H., O'Neill V., Siddiqui N., Seiden M.V., and Kaye S.B. Phase I trial of intraperitoneal injection of the E1B-55-kD-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer. J Clin Oncol 20 (2002) 1562-1569
-
(2002)
J Clin Oncol
, vol.20
, pp. 1562-1569
-
-
Vasey, P.A.1
Shulman, L.N.2
Campos, S.3
Davis, J.4
Gore, M.5
Johnston, S.6
Kirn, D.H.7
O'Neill, V.8
Siddiqui, N.9
Seiden, M.V.10
Kaye, S.B.11
-
97
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev L.T., Vu B.T., Graves B., Carvajal D., Podlaski F., Filipovic Z., Kong N., Kammlott U., Lukacs C., Klein C., Fotouhi N., and Liu E.A. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303 (2004) 844-848
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
Fotouhi, N.11
Liu, E.A.12
-
98
-
-
0031022938
-
Field cancerisation and polyclonal p53 mutation in the upper aero-digestive tract
-
Waridel F., Estreicher A., Bron L., Flaman J.-M., Fontolliet C., Monnier P., Frebourg F., and Iggo R. Field cancerisation and polyclonal p53 mutation in the upper aero-digestive tract. Oncogene 14 (1997) 163-169
-
(1997)
Oncogene
, vol.14
, pp. 163-169
-
-
Waridel, F.1
Estreicher, A.2
Bron, L.3
Flaman, J.-M.4
Fontolliet, C.5
Monnier, P.6
Frebourg, F.7
Iggo, R.8
-
99
-
-
0034657333
-
Comparison of TP53 mutations identified by oligonucleotide microarray and conventional DNA sequence analysis
-
Wen W.H., Bernstein L., Lescallett J., Beazer-Barclay Y., Sullivan-Halley J., and White M. Comparison of TP53 mutations identified by oligonucleotide microarray and conventional DNA sequence analysis. Cancer Res 60 (2000) 2716-2722
-
(2000)
Cancer Res
, vol.60
, pp. 2716-2722
-
-
Wen, W.H.1
Bernstein, L.2
Lescallett, J.3
Beazer-Barclay, Y.4
Sullivan-Halley, J.5
White, M.6
-
100
-
-
85047700479
-
Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control
-
Wiest T., Schwarz E., Enders C., Flechtenmacher C., and Bosch F.X. Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control. Oncogene 21 (2002) 1510-1517
-
(2002)
Oncogene
, vol.21
, pp. 1510-1517
-
-
Wiest, T.1
Schwarz, E.2
Enders, C.3
Flechtenmacher, C.4
Bosch, F.X.5
-
101
-
-
12244262241
-
Specific p53 mutations predict poor prognosis in oral squamous cell carcinoma
-
Yamazaki Y., Chiba I., Hirai A., Sugiura C., Notani K., Kashiwazaki H., Tei K., Totsuka Y., and Fukuda H. Specific p53 mutations predict poor prognosis in oral squamous cell carcinoma. Oral Oncol 39 (2003) 163-169
-
(2003)
Oral Oncol
, vol.39
, pp. 163-169
-
-
Yamazaki, Y.1
Chiba, I.2
Hirai, A.3
Sugiura, C.4
Notani, K.5
Kashiwazaki, H.6
Tei, K.7
Totsuka, Y.8
Fukuda, H.9
-
102
-
-
0032161624
-
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
-
Yang A., Kaghad M., Wang Y., Gillett E., Fleming M.D., Dotsch V., Andrews N.C., Caput D., and McKeon F. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 2 (1998) 305-316
-
(1998)
Mol Cell
, vol.2
, pp. 305-316
-
-
Yang, A.1
Kaghad, M.2
Wang, Y.3
Gillett, E.4
Fleming, M.D.5
Dotsch, V.6
Andrews, N.C.7
Caput, D.8
McKeon, F.9
-
103
-
-
0032533514
-
The potential tumor suppressor p73 differentially regulates cellular p53 target genes
-
Zhu J.J., Jiang J., Zhou W., and Chen X. The potential tumor suppressor p73 differentially regulates cellular p53 target genes. Cancer Res 58 (1998) 5061-5065
-
(1998)
Cancer Res
, vol.58
, pp. 5061-5065
-
-
Zhu, J.J.1
Jiang, J.2
Zhou, W.3
Chen, X.4
|