A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

Nature Genetics

Volumn 25, Issue 1, 2000, Pages 47-54

  Marin, Maria Carmen ^a   Jost, Christine A ^a   Brooks, Louise A ^b,c   Irwin, Meredith S ^a   O'Nions, Jenny ^b,c   Tidy, John A ^d   James, Nick ^e   McGregor, Jane M ^f   Harwood, Catherine A ^f   Yulug, Isik G ^c   Vousden, Karen H ^g   Allday, Martin J ^h   Gusterson, Barry ^c   Ikawa, Shuntaro ⁱ   Hinds, Philip W ^a   Crook, Tim ^c   Kaelin Jr , William G ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

^e UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^f Centre for Cutaneous Research   (United Kingdom)

^g NATIONAL CANCER INSTITUTE   (United States)

^h ST MARY S HOSPITAL   (United Kingdom)

ⁱ TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; NUCLEIC ACID; PROTEIN P53; PROTEIN P73;

ALLELE; ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENETIC POLYMORPHISM; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; SKIN CARCINOMA; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE; VULVA CARCINOMA;

ALLELES; ARGININE; CARCINOMA, SQUAMOUS CELL; CELL LINE; CODON; DNA-BINDING PROTEINS; GENES, P53; GENES, TUMOR SUPPRESSOR; GERM-LINE MUTATION; HETEROZYGOTE DETECTION; HUMANS; MACROMOLECULAR SUBSTANCES; MUTAGENESIS, SITE-DIRECTED; NUCLEAR PROTEINS; POLYMORPHISM, GENETIC; PROLINE; PROTEIN BINDING; PROTEIN CONFORMATION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0034063604     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/75586     Document Type: Article

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