Bax inhibitor-1 protects neurons from oxygen-glucose deprivation

Journal of Molecular Neuroscience

Volumn 29, Issue 1, 2006, Pages 1-8

  Dohm, Christoph P ^a   Siedenberg, Sandra ^a   Liman, Jan ^a   Esposito, Alessandro ^b   Wouters, Fred S ^b   Reed, John C ^c   Bähr, Mathias ^a   Kermer, Pawel ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b EUROPEAN NEUROSCIENCE INSTITUTE   (Germany)

^c BURNHAM INSTITUTE   (United States)

Author keywords

Bax inhibitor 1; Endoplasmic reticulum; Human SH SY5Y cells; Neuronal apoptosis; Neuroprotection; Oxygen glucose deprivation; Rat CSM14.1 cells

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); BAX INHIBITOR 1; NEUROPROTECTIVE AGENT; STAUROSPORINE; THAPSIGARGIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELLULAR DISTRIBUTION; ENDOPLASMIC RETICULUM; ENZYME INHIBITION; GENE OVEREXPRESSION; ISCHEMIA; NERVE CELL; NEUROPROTECTION; NONHUMAN; RAT;

ANIMALS; CELL DEATH; CELL LINE; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; GLUCOSE; HUMANS; MEMBRANE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; OXYGEN; RATS; RECOMBINANT FUSION PROTEINS; THAPSIGARGIN;

MAMMALIA;

EID: 33744950129     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1385/JMN:29:1:1     Document Type: Article

References (24)

1. Alnemri E. S., Livingston D. J., Nicholson D. W., Salvesen G., Thornberry N. A., Wong W. W., and Yuan J. (1996) Human ICE/CED-3 protease nomenclature. Cell 87, 171.
2. Alvarez M. E. (2000) Salicylic acid in the machinery of hypersensitive cell death and disease resistance. Plant Mol. Biol. 44, 429-442.
3. Bolduc N., Quellet M., Pitre F., and Brisson L. F. (2003) Molecular characterization of two plant BI-1 homologues which suppress Bax-induced apoptosis in human 293 cells. Planta 216, 377-386.
4. Chae H. J., Ke N., Kim H. R., Chen S., Godzik A., Dickman M., and Reed J. C. (2003) Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast. Gene 323, 101-113.
5. Chae H. J., Kim H. R., Xu C., Bailly-Maitre B., Krajewska M., Krajewski S., et al. (2004) BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol. Cell 15, 355-366.
6. Hückelhoven R. (2004) BAX Inhibitor-1, an ancient cell death suppressor in animals and plants with prokaryotic relatives. Apoptosis 9, 299-307.
7. Hückelhoven R., Dechert C., and Kogel K. H. (2003) Overexpression of barley BAX Inhibitor-1 induces breakdown of mlo-mediated penetration resistance to Blumeria graminis. Proc. Natl. Acad. Sci. U. S. A. 100, 5555-5560.
8. Katayama T., Imaizumi K., Manabe T., Hitomi J., Kudo T., and Tohyama M. (2004) Induction of neuronal death by ER stress in Alzheimer's disease. J. Chem. Neuroanat. 28, 67-78.
9. Kawai M., Pan L., Reed J. C., and Uchimiya H. (1999) Evolutionally conserved plant homologue of the Bax inhibitor-1 (BI-1) gene capable of suppressing Bax-induced cell death in yeast. FEBS Lett. 464, 143-147.
10. Kawai-Yamada M., Jin L., Yoshinaga K., Hirata A., and Uchimiya H. (2001) Mammalian Bax-induced plant cell death can be downregulated by overexpression of Arabidopsis Bax Inhibitor-1 (AtBI-1). Proc. Natl. Acad. Sci. U. S. A. 98, 12295-12300.
11. Kawai-Yamada M., Ohori Y., and Uchimiya H. (2004) Dissection of Arabidopsis Bax inhibitor-1 suppressing Bax-, hydrogen peroxide-, and salicylic acid-induced cell death. Plant Cell 16, 21-32.
12. Kermer P., Krajewska M., Zapata J. M., Takayama S., Mai J., Krajewski S., and Reed J. C. (2002) Bag1 is a regulator and marker of neuronal differentiation. Cell Death Differ. 9, 405-413.
13. Kermer P., Liman J., Weishaupt J. H., and Bähr M. (2004) Neuronal apoptosis in neurodegenerative diseases: from basic research to clinical application. Neurodegenerative Diseases 1, 9-19.
14. Lipton P. (1999) Ischemic cell death in brain neurons. Physiol. Rev. 79, 1431-1568.
15. Mancini M., Machamer C. E., Roy S., Nicholson D. W., Thornberry N. A., Casciola-Rosen L. A., and Rosen A. (2000) Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis. J. Cell Biol. 149, 603-612.
16. Matsumura H., Nirasawa S., Kiba A., Urasaki N., Saitoh H., Ito M., et al. (2003) Overexpression of Bax inhibitor suppresses the fungal elicitor-induced cell death in rice (Oryza sativa L.) cells. Plant J. 33, 425-434.
17. Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B. A., and Yuan J. (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403, 98-103.
18. Punj V. and Chakrabarty A. M. (2003) Redox proteins in mammalian cell death: an evolutionarily conserved function in mitochondria and prokaryotes. Cell. Microbiol. 5, 225-231.
19. Reed J. C. (2000) Mechanisms of apoptosis. Am. J. Pathol 157, 1415-1430.
20. Sanchez P., de Torres Zabala M., and Grant M. (2000) AtBI-1, a plant homologue of Bax inhibitor-1, suppresses Bax-induced cell death in yeast and is rapidly upregulated during wounding and pathogen challenge. Plant J. 21, 393-399.
21. Walter L., Dirks B., Rothermel E., Heyens M., Szpirer C., Levan G., and Gunther E. (1994) A novel, conserved gene of the rat that is developmentally regulated in the testis. Mamm. Genome 5, 216-221.
22. Walter L., Marynen P., Szpirer J., Levan G., and Gunther E. (1995) Identification of a novel conserved human gene, TEGT. Genomics 28, 301-304.
23. Xu Q. and Reed J. C. (1998) Bax Inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast. Mol. Cell 1, 337-346.
24. Zhong L. T., Sarafian T, Kane D. J., Charles A. C., Mah S. P., Edwards R. H., and Bredesen D. E. (1993) bcl-2 inhibits death of central neural cells induced by multiple agents. Proc. Natl. Acad. Sci. U. S. A. 90, 4533-4537.