Secondary bioenergetic failure after transient focal ischaemia is due to mitochondrial injury

Acta Physiologica Scandinavica

Volumn 156, Issue 2, 1996, Pages 149-150

  Kuroda, S ^a   Katsura, K I ^a   Tsuchidate, R ^a   Siesjo B K ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Brain; Focal ischaemia; Mitochondrial function; Recirculation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOENERGY; BRAIN ISCHEMIA; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION; STROKE;

EID: 0029872044     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1996.449170000.x     Document Type: Article

References (8)

1. Almeida, A., Allen, K., Bates, T. & Clark, J. 1995. Effects of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory-chain in the gerbil brain. J Neurochem 65, 1698-1703.
2. Del Zoppo, G. J., Schmid-Schönbein, G.W., Mori, E., Copeland, B.R. & Chang C.M. 1991. Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons Stroke 22, 1276-1283.
3. Folbergrová, J., Zhao, Q., Katsura, K. & Siesjö, B.K. 1995. N-tert-Butyl-a-phenylnitrone improves recovery of brain energy state in rats following transient focal ischaemia. Proc. Natl. Acad. Sci. USA 92, 5055-5061.
4. Garcia, J.H., Liu, K.F., Yoshida, Y., Lian, J., Chen, S. & Del Zoppo, G. J. 1994. Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat). Am J Pathol 144, 188-199.
5. Hillered, L., Siesjö, B.K. & Arfors, K. 1984. Mitochondrial response to transient forebrain ischaemia and recirculation in the rat. J Cereb Blood Flow Metab 4, 438-446.
6. Sims, N. & Blass, J. 1986. Expression of classical mitochondrial respiratory responses in homogenates of rat forebrain. J Neurochem 47, 496-505.
7. Sims, N. & Pulsinelli, W. 1987. Altered mitochondrial respiration in selectively vulnerable brain subregions following transient forebrain ischaemia in the rat. J Neurochem 49, 1367-1374.
8. Zhao, Q., Pahlmark, K., Smith, M. & Siesjö, B.K. 1994. Delayed treatment with the spin trap a-phenyl-N-tert-butyl nitrone (PBN) reduced infarct size following transient middle cerebral artery occlusion in rats. Acta Physiol Scand 152, 349-350.