-
1
-
-
0003148419
-
Parkinsonism
-
Rowland L. (Ed), Lippincott Williams & Wilkins, Philadelphia
-
Fahn S., and Przedborski S. Parkinsonism. In: Rowland L. (Ed). Merritt's neurology (2000), Lippincott Williams & Wilkins, Philadelphia 679-693
-
(2000)
Merritt's neurology
, pp. 679-693
-
-
Fahn, S.1
Przedborski, S.2
-
2
-
-
0038727936
-
Description of Parkinson's disease as a clinical syndrome
-
Fahn S. Description of Parkinson's disease as a clinical syndrome. Ann NY Acad Sci 991 (2003) 1-14
-
(2003)
Ann NY Acad Sci
, vol.991
, pp. 1-14
-
-
Fahn, S.1
-
3
-
-
0029094141
-
Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease
-
Seibyl J., Marek K., Quinlan D., Sheff K., Zoghbi S., Zea-Ponce Y., et al. Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease. Ann Neurol 38 (1995) 589-598
-
(1995)
Ann Neurol
, vol.38
, pp. 589-598
-
-
Seibyl, J.1
Marek, K.2
Quinlan, D.3
Sheff, K.4
Zoghbi, S.5
Zea-Ponce, Y.6
-
4
-
-
0028931484
-
Assessment of disease severity in parkinsonism with fluorine-18-fluorodeoxyglucose and PET
-
Eidelberg D., Moeller J., Ishikawa T., Dhawan V., Spetsieris P., Chaly T., et al. Assessment of disease severity in parkinsonism with fluorine-18-fluorodeoxyglucose and PET. J Nucl Med 36 (1995) 378-383
-
(1995)
J Nucl Med
, vol.36
, pp. 378-383
-
-
Eidelberg, D.1
Moeller, J.2
Ishikawa, T.3
Dhawan, V.4
Spetsieris, P.5
Chaly, T.6
-
5
-
-
0028172598
-
Longitudinal fluorodopa positron emission tomographic studies of the evolution of idiopathic Parkinsonism
-
Snow B., Lee C., Schulzer M., Mak E., and Calne D. Longitudinal fluorodopa positron emission tomographic studies of the evolution of idiopathic Parkinsonism. Ann Neurol 36 (1994) 759-764
-
(1994)
Ann Neurol
, vol.36
, pp. 759-764
-
-
Snow, B.1
Lee, C.2
Schulzer, M.3
Mak, E.4
Calne, D.5
-
6
-
-
0029981856
-
An [F-18]dopa-PET and clinical study of the rate of progression in Parkinson's disease
-
Morrish P., Sawle G., and Brooks D. An [F-18]dopa-PET and clinical study of the rate of progression in Parkinson's disease. Brain 119 (1996) 585-591
-
(1996)
Brain
, vol.119
, pp. 585-591
-
-
Morrish, P.1
Sawle, G.2
Brooks, D.3
-
7
-
-
0033910602
-
Correlation of Parkinson's disease severity and duration with 123I-FP-CIT SPECT striatal uptake
-
Benamer H., Patterson J., Wyper D., Hadley D., Macphee G., and Grosset D. Correlation of Parkinson's disease severity and duration with 123I-FP-CIT SPECT striatal uptake. Mov Disord 15 (2000) 692-698
-
(2000)
Mov Disord
, vol.15
, pp. 692-698
-
-
Benamer, H.1
Patterson, J.2
Wyper, D.3
Hadley, D.4
Macphee, G.5
Grosset, D.6
-
8
-
-
0028826015
-
The frequency of idiopathic Parkinson's disease by age, ethnic group, and sex in northern Manhattan, 1988-1993
-
Mayeux R., Marder K., Cote L., Denaro J., Hemenegildo N., Mejia H., et al. The frequency of idiopathic Parkinson's disease by age, ethnic group, and sex in northern Manhattan, 1988-1993. Am J Epidemiol 142 (1995) 820-827
-
(1995)
Am J Epidemiol
, vol.142
, pp. 820-827
-
-
Mayeux, R.1
Marder, K.2
Cote, L.3
Denaro, J.4
Hemenegildo, N.5
Mejia, H.6
-
9
-
-
0031013848
-
Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease
-
de Rijk M., Tzourio C., Breteler M., Dartigues J., Amaducci L., Lopez-Pousa S., et al. Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease. J Neurol Neurosurg Psychiatry 62 (1997) 10-15
-
(1997)
J Neurol Neurosurg Psychiatry
, vol.62
, pp. 10-15
-
-
de Rijk, M.1
Tzourio, C.2
Breteler, M.3
Dartigues, J.4
Amaducci, L.5
Lopez-Pousa, S.6
-
10
-
-
0033819269
-
Influence of strict, intermediate, and broad diagnostic criteria on the age- and sex-specific incidence of Parkinson's disease
-
Bower J., Maraganore D., McDonnell S., and Rocca W. Influence of strict, intermediate, and broad diagnostic criteria on the age- and sex-specific incidence of Parkinson's disease. Mov Disord 15 (2000) 819-825
-
(2000)
Mov Disord
, vol.15
, pp. 819-825
-
-
Bower, J.1
Maraganore, D.2
McDonnell, S.3
Rocca, W.4
-
11
-
-
0037246310
-
Systematic review of incidence studies of Parkinson's disease
-
Twelves D., Perkins K., and Counsell C. Systematic review of incidence studies of Parkinson's disease. Mov Disord 18 (2003) 19-31
-
(2003)
Mov Disord
, vol.18
, pp. 19-31
-
-
Twelves, D.1
Perkins, K.2
Counsell, C.3
-
12
-
-
0034649437
-
Parkinson's disease and parkinsonism in a longitudinal study: two-fold higher incidence in men. ILSA Working Group. Italian Longitudinal Study on Aging
-
Baldereschi M., Di Carlo A., Rocca W., Vanni P., Maggi S., Perissinotto E., et al. Parkinson's disease and parkinsonism in a longitudinal study: two-fold higher incidence in men. ILSA Working Group. Italian Longitudinal Study on Aging. Neurology 55 (2000) 1358-1363
-
(2000)
Neurology
, vol.55
, pp. 1358-1363
-
-
Baldereschi, M.1
Di Carlo, A.2
Rocca, W.3
Vanni, P.4
Maggi, S.5
Perissinotto, E.6
-
13
-
-
0037388651
-
Parkinson disease with old-age onset: a comparative study with subjects with middle-age onset
-
Diederich N., Moore C., Leurgans S., Chmura T., and Goetz C. Parkinson disease with old-age onset: a comparative study with subjects with middle-age onset. Arch Neurol 60 (2003) 529-533
-
(2003)
Arch Neurol
, vol.60
, pp. 529-533
-
-
Diederich, N.1
Moore, C.2
Leurgans, S.3
Chmura, T.4
Goetz, C.5
-
14
-
-
0026569594
-
Aging produces a specific pattern of striatal dopamine loss: implications for the etiology of idiopathic Parkinson's disease
-
Kish S., Shannak K., Rajput A., Deck J., and Hornykiewicz O. Aging produces a specific pattern of striatal dopamine loss: implications for the etiology of idiopathic Parkinson's disease. J Neurochem 58 (1992) 642-648
-
(1992)
J Neurochem
, vol.58
, pp. 642-648
-
-
Kish, S.1
Shannak, K.2
Rajput, A.3
Deck, J.4
Hornykiewicz, O.5
-
15
-
-
0024448235
-
Striatal dopamine deficiency in Parkinson's disease: role of aging
-
Scherman D., Desnos C., Darchen F., Pollak P., Javoy-Agid F., and Agid Y. Striatal dopamine deficiency in Parkinson's disease: role of aging. Ann Neurol 26 (1989) 551-557
-
(1989)
Ann Neurol
, vol.26
, pp. 551-557
-
-
Scherman, D.1
Desnos, C.2
Darchen, F.3
Pollak, P.4
Javoy-Agid, F.5
Agid, Y.6
-
16
-
-
0035138143
-
Imaging of dopamine transporters with [123I]FP-CIT SPECT does not suggest a significant effect of age on the symptomatic threshold of disease in Parkinson's disease
-
Booij J., Bergmans P., Winogrodzka A., Speelman J., and Wolters E. Imaging of dopamine transporters with [123I]FP-CIT SPECT does not suggest a significant effect of age on the symptomatic threshold of disease in Parkinson's disease. Synapse 39 (2001) 101-108
-
(2001)
Synapse
, vol.39
, pp. 101-108
-
-
Booij, J.1
Bergmans, P.2
Winogrodzka, A.3
Speelman, J.4
Wolters, E.5
-
17
-
-
0033959077
-
Preservation of midbrain catecholaminergic neurons in very old human subjects
-
Kubis N., Faucheux B., Ransmayr G., Damier P., Duyckaerts C., Henin D., et al. Preservation of midbrain catecholaminergic neurons in very old human subjects. Brain 123 (2000) 366-373
-
(2000)
Brain
, vol.123
, pp. 366-373
-
-
Kubis, N.1
Faucheux, B.2
Ransmayr, G.3
Damier, P.4
Duyckaerts, C.5
Henin, D.6
-
18
-
-
0025954066
-
Ageing and Parkinson's disease: substantia nigra regional selectivity
-
Fearnley J., and Lees A. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114 (1991) 2283-2301
-
(1991)
Brain
, vol.114
, pp. 2283-2301
-
-
Fearnley, J.1
Lees, A.2
-
19
-
-
0000555418
-
Piperidine derivatives. Part III. 4-arylpiperidines
-
Zeiring A., Berger L., Heineman S., and Lee J. Piperidine derivatives. Part III. 4-arylpiperidines. J Org Chem 12 (1947) 894-903
-
(1947)
J Org Chem
, vol.12
, pp. 894-903
-
-
Zeiring, A.1
Berger, L.2
Heineman, S.3
Lee, J.4
-
20
-
-
33947466070
-
The aminomethylation of olefins. IV. The formation of 1-alkyl-4-aryl-1.2.3.6-tetrahydropyridines
-
Schmidle C., and Mansfield R. The aminomethylation of olefins. IV. The formation of 1-alkyl-4-aryl-1.2.3.6-tetrahydropyridines. Am J Chem 78 (1955) 425-428
-
(1955)
Am J Chem
, vol.78
, pp. 425-428
-
-
Schmidle, C.1
Mansfield, R.2
-
21
-
-
0018608356
-
Chronic Parkinsonism secondary to intravenous injection of meperidine analogues
-
Davis G., Williams A., Markey S., Ebert M., Caine E., Reichert C., et al. Chronic Parkinsonism secondary to intravenous injection of meperidine analogues. Psychiatry Res 1 (1979) 249-254
-
(1979)
Psychiatry Res
, vol.1
, pp. 249-254
-
-
Davis, G.1
Williams, A.2
Markey, S.3
Ebert, M.4
Caine, E.5
Reichert, C.6
-
22
-
-
0021753399
-
Chronic parkinsonism secondary to intranasal administration of a product of meperidine-analogue synthesis
-
Wright J., Wall R., Perry T., and Paty D. Chronic parkinsonism secondary to intranasal administration of a product of meperidine-analogue synthesis. N Engl J Med 310 (1984) 325
-
(1984)
N Engl J Med
, vol.310
, pp. 325
-
-
Wright, J.1
Wall, R.2
Perry, T.3
Paty, D.4
-
23
-
-
0005444118
-
Parkinson's disease in a chemist working with 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
-
Langston J., and Ballard P. Parkinson's disease in a chemist working with 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. N Engl J Med 309 (1983) 310
-
(1983)
N Engl J Med
, vol.309
, pp. 310
-
-
Langston, J.1
Ballard, P.2
-
24
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston J., Ballard P., Tetrud J., and Irwin I. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219 (1983) 979-980
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.1
Ballard, P.2
Tetrud, J.3
Irwin, I.4
-
26
-
-
0001496694
-
A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methl-4-phenyl-1,2,36-tetrahydropyridine
-
Burns R., Chiueh C., Markey S., Ebert M., Jacobowitz D., and Kopin I. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methl-4-phenyl-1,2,36-tetrahydropyridine. Proc Natl Acad Sci USA 80 (1983) 4546-4550
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 4546-4550
-
-
Burns, R.1
Chiueh, C.2
Markey, S.3
Ebert, M.4
Jacobowitz, D.5
Kopin, I.6
-
27
-
-
0026458624
-
Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
-
Widner H., Tetrud J., Rehncrona S., Snow B., Brundin P., Gustavii B., et al. Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). N Engl J Med 327 (1992) 1556-1563
-
(1992)
N Engl J Med
, vol.327
, pp. 1556-1563
-
-
Widner, H.1
Tetrud, J.2
Rehncrona, S.3
Snow, B.4
Brundin, P.5
Gustavii, B.6
-
28
-
-
0014705297
-
Modification of chronic manganese poisoning. Treatment with L-dopa or 5-OH tryptophane
-
Mena I., Court J., Fuenzalida S., Papavasiliou P., and Cotzias G. Modification of chronic manganese poisoning. Treatment with L-dopa or 5-OH tryptophane. N Engl J Med 282 (1970) 5-10
-
(1970)
N Engl J Med
, vol.282
, pp. 5-10
-
-
Mena, I.1
Court, J.2
Fuenzalida, S.3
Papavasiliou, P.4
Cotzias, G.5
-
29
-
-
0015988134
-
Chronic manganese intoxication
-
Cook D., Fahn S., and Brait K. Chronic manganese intoxication. Arch Neurol 30 (1974) 59-64
-
(1974)
Arch Neurol
, vol.30
, pp. 59-64
-
-
Cook, D.1
Fahn, S.2
Brait, K.3
-
30
-
-
0024455148
-
Chronic manganese intoxication
-
Huang C., Chu N., Lu C., Wang J., Tsai J., Tzeng J., et al. Chronic manganese intoxication. Arch Neurol 46 (1989) 1104-1106
-
(1989)
Arch Neurol
, vol.46
, pp. 1104-1106
-
-
Huang, C.1
Chu, N.2
Lu, C.3
Wang, J.4
Tsai, J.5
Tzeng, J.6
-
31
-
-
0026608742
-
Epidemiology of Parkinson's disease
-
Tanner C. Epidemiology of Parkinson's disease. Neurol Clin 10 (1992) 317-329
-
(1992)
Neurol Clin
, vol.10
, pp. 317-329
-
-
Tanner, C.1
-
32
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R., Sherer T., MacKenzie G., Garcia-Osuna M., Panov A., and Greenamyre J. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 3 (2000) 1301-1306
-
(2000)
Nat Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.5
Greenamyre, J.6
-
33
-
-
0036714747
-
A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease
-
Hernan M., Takkouche B., Caamano-Isorna F., and Gestal-Otero J. A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease. Ann Neurol 52 (2002) 276-284
-
(2002)
Ann Neurol
, vol.52
, pp. 276-284
-
-
Hernan, M.1
Takkouche, B.2
Caamano-Isorna, F.3
Gestal-Otero, J.4
-
34
-
-
0033608187
-
Parkinson disease in twins: an etiologic study
-
Tanner C., Ottman R., Goldman S., Ellenberg J., Chan P., Mayeux R., et al. Parkinson disease in twins: an etiologic study. JAMA 281 (1999) 341-366
-
(1999)
JAMA
, vol.281
, pp. 341-366
-
-
Tanner, C.1
Ottman, R.2
Goldman, S.3
Ellenberg, J.4
Chan, P.5
Mayeux, R.6
-
35
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos M., Lavedan C., Leroy E., Ide S., Dehejia A., Dutra A., et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276 (1997) 2045-2047
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.1
Lavedan, C.2
Leroy, E.3
Ide, S.4
Dehejia, A.5
Dutra, A.6
-
36
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger R., Kuhn W., Muller T., Woitalla D., Graeber M., Kosel S., et al. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat Genet 18 (1998) 106-108
-
(1998)
Nat Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
-
37
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini M., Schmidt M., Lee V., Trojanowski J., Jakes R., and Goedert M. Alpha-synuclein in Lewy bodies. Nature 388 (1997) 839-840
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.1
Schmidt, M.2
Lee, V.3
Trojanowski, J.4
Jakes, R.5
Goedert, M.6
-
38
-
-
0027489773
-
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease
-
Ueda K., Fukushima H., Masliah E., Xia Y., Iwai A., Yoshimoto M., et al. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc Natl Acad Sci USA 90 (1993) 11282-11286
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11282-11286
-
-
Ueda, K.1
Fukushima, H.2
Masliah, E.3
Xia, Y.4
Iwai, A.5
Yoshimoto, M.6
-
39
-
-
0032952414
-
Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions
-
Engelender S., Kaminsky Z., Guo X., Sharp A., Amaravi R., Kleiderlein J., et al. Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nat Genet 22 (1999) 110-114
-
(1999)
Nat Genet
, vol.22
, pp. 110-114
-
-
Engelender, S.1
Kaminsky, Z.2
Guo, X.3
Sharp, A.4
Amaravi, R.5
Kleiderlein, J.6
-
40
-
-
0036777847
-
Synergistic effects of pesticides and metals on the fibrillation of alpha-synuclein: implications for Parkinson's disease
-
Uversky V., Li J., Bower K., and Fink A. Synergistic effects of pesticides and metals on the fibrillation of alpha-synuclein: implications for Parkinson's disease. Neurotoxicology 23 (2002) 527-536
-
(2002)
Neurotoxicology
, vol.23
, pp. 527-536
-
-
Uversky, V.1
Li, J.2
Bower, K.3
Fink, A.4
-
41
-
-
0035834360
-
Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct
-
Conway K., Rochet J., Bieganski R., and Lansbury Jr. P. Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct. Science 294 (2001) 1346-1349
-
(2001)
Science
, vol.294
, pp. 1346-1349
-
-
Conway, K.1
Rochet, J.2
Bieganski, R.3
Lansbury Jr., P.4
-
42
-
-
34247141410
-
Certain metals trigger fibrillation of methionine-oxidized alpha-synuclein
-
Yamin G., Glaser C., Uversky V., and Fink A. Certain metals trigger fibrillation of methionine-oxidized alpha-synuclein. J Biol Chem 16 (2003) 16
-
(2003)
J Biol Chem
, vol.16
, pp. 16
-
-
Yamin, G.1
Glaser, C.2
Uversky, V.3
Fink, A.4
-
43
-
-
0035887860
-
Induction of alpha-synuclein aggregation by intracellular nitrative insult
-
Paxinou E., Chen Q., Weisse M., Giasson B., Norris E., Rueter S., et al. Induction of alpha-synuclein aggregation by intracellular nitrative insult. J Neurosci 21 (2001) 8053-8061
-
(2001)
J Neurosci
, vol.21
, pp. 8053-8061
-
-
Paxinou, E.1
Chen, Q.2
Weisse, M.3
Giasson, B.4
Norris, E.5
Rueter, S.6
-
44
-
-
0036364454
-
The cell biology of alpha-synuclein: a sticky problem?
-
Cole N., and Murphy D. The cell biology of alpha-synuclein: a sticky problem?. Neuromolecular Med 1 (2002) 95-109
-
(2002)
Neuromolecular Med
, vol.1
, pp. 95-109
-
-
Cole, N.1
Murphy, D.2
-
45
-
-
0032102455
-
The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease
-
Clayton D., and George J. The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease. Trends Neurosci 21 (1998) 249-254
-
(1998)
Trends Neurosci
, vol.21
, pp. 249-254
-
-
Clayton, D.1
George, J.2
-
46
-
-
0023722437
-
Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal
-
Maroteaux L., Campanelli J., and Scheller R. Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal. J Neurosci 8 (1988) 2804-2815
-
(1988)
J Neurosci
, vol.8
, pp. 2804-2815
-
-
Maroteaux, L.1
Campanelli, J.2
Scheller, R.3
-
47
-
-
0034077041
-
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich A., Schmitz Y., Farinas I., Choi-Lundberg D., Ho W., Verdugo J., et al. Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron 25 (2000) 239-252
-
(2000)
Neuron
, vol.25
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
Choi-Lundberg, D.4
Ho, W.5
Verdugo, J.6
-
48
-
-
0037109727
-
Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein
-
Cabin D., Shimazu K., Murphy D., Cole N., Gottschalk W., McIlwain K., et al. Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein. J Neurosci 22 (2002) 8797-8807
-
(2002)
J Neurosci
, vol.22
, pp. 8797-8807
-
-
Cabin, D.1
Shimazu, K.2
Murphy, D.3
Cole, N.4
Gottschalk, W.5
McIlwain, K.6
-
49
-
-
0034193399
-
Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
-
Murphy D., Rueter S., Trojanowski J., and Lee V. Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons. J Neurosci 20 (2000) 3214-3220
-
(2000)
J Neurosci
, vol.20
, pp. 3214-3220
-
-
Murphy, D.1
Rueter, S.2
Trojanowski, J.3
Lee, V.4
-
50
-
-
0037092442
-
A role for alpha-synuclein in the regulation of dopamine biosynthesis
-
Perez R., Waymire J., Lin E., Liu J., Guo F., and Zigmond M. A role for alpha-synuclein in the regulation of dopamine biosynthesis. J Neurosci 22 (2002) 3090-3099
-
(2002)
J Neurosci
, vol.22
, pp. 3090-3099
-
-
Perez, R.1
Waymire, J.2
Lin, E.3
Liu, J.4
Guo, F.5
Zigmond, M.6
-
51
-
-
0035066885
-
Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis
-
Lee F., Liu F., Pristupa Z., and Niznik H. Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis. FASEB J 15 (2001) 916-926
-
(2001)
FASEB J
, vol.15
, pp. 916-926
-
-
Lee, F.1
Liu, F.2
Pristupa, Z.3
Niznik, H.4
-
52
-
-
0242300619
-
Alpha-synuclein locus triplication in PD
-
Singleton A., Farrer M., Johnson J., Singleton A., Hague S., Kachergus J., Hulihan M., et al. Alpha-synuclein locus triplication in PD. Science 302 (2003) 841
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
-
53
-
-
0037195109
-
Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP
-
Dauer W., Kholodilov N., Vila M., Trillat A., Goodchild R., Larsen K., et al. Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP. Proc Natl Acad Sci USA 99 (2002) 14524-14529
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14524-14529
-
-
Dauer, W.1
Kholodilov, N.2
Vila, M.3
Trillat, A.4
Goodchild, R.5
Larsen, K.6
-
54
-
-
0037064078
-
Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line
-
Lotharius J., Barg S., Wiekop P., Lundberg C., Raymon H., and Brundin P. Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line. J Biol Chem 277 (2002) 38884-38894
-
(2002)
J Biol Chem
, vol.277
, pp. 38884-38894
-
-
Lotharius, J.1
Barg, S.2
Wiekop, P.3
Lundberg, C.4
Raymon, H.5
Brundin, P.6
-
55
-
-
0035854437
-
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease
-
Shimura H., Schlossmacher M., Hattori N., Frosch M., Trockenbacher A., Schneider R., et al. Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science 293 (2001) 263-269
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.2
Hattori, N.3
Frosch, M.4
Trockenbacher, A.5
Schneider, R.6
-
56
-
-
0041589248
-
Alpha-synuclein is degraded by both autophagy and the proteasome
-
Webb J., Ravikumar B., Atkins J., Skepper J., and Rubinsztein D. Alpha-synuclein is degraded by both autophagy and the proteasome. J Biol Chem 28 (2003) 25009-25013
-
(2003)
J Biol Chem
, vol.28
, pp. 25009-25013
-
-
Webb, J.1
Ravikumar, B.2
Atkins, J.3
Skepper, J.4
Rubinsztein, D.5
-
57
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392 (1998) 605-608
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
-
58
-
-
0342368772
-
Association between early-onset Parkinson's disease and mutations in the parkin gene
-
Lucking C., Durr A., Bonifati V., Vaughan J., De Michele G., Gasser T., et al. Association between early-onset Parkinson's disease and mutations in the parkin gene. N Engl J Med 342 (2000) 1560-1567
-
(2000)
N Engl J Med
, vol.342
, pp. 1560-1567
-
-
Lucking, C.1
Durr, A.2
Bonifati, V.3
Vaughan, J.4
De Michele, G.5
Gasser, T.6
-
59
-
-
0034848395
-
Lewy bodies and parkinsonism in families with parkin mutations
-
Farrer M., Chan P., Chen R., Tan L., Lincoln S., Hernandez D., et al. Lewy bodies and parkinsonism in families with parkin mutations. Ann Neurol 50 (2001) 293-300
-
(2001)
Ann Neurol
, vol.50
, pp. 293-300
-
-
Farrer, M.1
Chan, P.2
Chen, R.3
Tan, L.4
Lincoln, S.5
Hernandez, D.6
-
60
-
-
12244262766
-
Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease
-
Foroud T., Uniacke S., Liu L., Pankratz N., Rudolph A., Halter C., et al. Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease. Neurology 60 (2003) 796-801
-
(2003)
Neurology
, vol.60
, pp. 796-801
-
-
Foroud, T.1
Uniacke, S.2
Liu, L.3
Pankratz, N.4
Rudolph, A.5
Halter, C.6
-
61
-
-
0034700158
-
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
-
Zhang Y., Gao J., Chung K., Huang H., Dawson V., and Dawson T. Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc Natl Acad Sci USA 97 (2000) 13354-13359
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13354-13359
-
-
Zhang, Y.1
Gao, J.2
Chung, K.3
Huang, H.4
Dawson, V.5
Dawson, T.6
-
62
-
-
0037422010
-
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
-
Staropoli J., McDermott C., Martinat C., Schulman B., Demireva E., and Abeliovich A. Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity. Neuron 37 (2003) 735-749
-
(2003)
Neuron
, vol.37
, pp. 735-749
-
-
Staropoli, J.1
McDermott, C.2
Martinat, C.3
Schulman, B.4
Demireva, E.5
Abeliovich, A.6
-
63
-
-
0037137702
-
Parkin protects against the toxicity associated with mutant alpha-synuclein
-
Petrucelli L., O'Farrell C., Lockhart P., Baptista M., Kehoe K., Vink L., et al. Parkin protects against the toxicity associated with mutant alpha-synuclein. Neuron 36 (2002) 1007-1019
-
(2002)
Neuron
, vol.36
, pp. 1007-1019
-
-
Petrucelli, L.1
O'Farrell, C.2
Lockhart, P.3
Baptista, M.4
Kehoe, K.5
Vink, L.6
-
64
-
-
0032190090
-
The ubiquitin pathway in Parkinson's disease
-
Leroy E., Boyer R., Auburger G., Leube B., Ulm G., Mezey E., et al. The ubiquitin pathway in Parkinson's disease. Nature 395 (1998) 451-452
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
Leube, B.4
Ulm, G.5
Mezey, E.6
-
65
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V., Rizzu P., van Baren M., Schaap O., Breedveld G., Krieger E., et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299 (2003) 256-259
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
van Baren, M.3
Schaap, O.4
Breedveld, G.5
Krieger, E.6
-
66
-
-
0037151769
-
Molecular features of human ubiquitin-like SUMO genes and their encoded proteins
-
Su H., and Li S. Molecular features of human ubiquitin-like SUMO genes and their encoded proteins. Gene 296 (2002) 65-73
-
(2002)
Gene
, vol.296
, pp. 65-73
-
-
Su, H.1
Li, S.2
-
67
-
-
0035813135
-
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor
-
Takahashi K., Taira T., Niki T., Seino C., Iguchi-Ariga S., and Ariga H. DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor. J Biol Chem 276 (2001) 37556-37563
-
(2001)
J Biol Chem
, vol.276
, pp. 37556-37563
-
-
Takahashi, K.1
Taira, T.2
Niki, T.3
Seino, C.4
Iguchi-Ariga, S.5
Ariga, H.6
-
68
-
-
0034906096
-
Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat
-
Mitsumoto A., Nakagawa Y., Takeuchi A., Okawa K., Iwamatsu A., and Takanezawa Y. Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat. Free Radic Res 35 (2001) 301-310
-
(2001)
Free Radic Res
, vol.35
, pp. 301-310
-
-
Mitsumoto, A.1
Nakagawa, Y.2
Takeuchi, A.3
Okawa, K.4
Iwamatsu, A.5
Takanezawa, Y.6
-
69
-
-
0032576605
-
Aggresomes: a cellular response to misfolded proteins
-
Johnston J., Ward C., and Kopito R. Aggresomes: a cellular response to misfolded proteins. J Cell Biol 143 (1998) 1883-1898
-
(1998)
J Cell Biol
, vol.143
, pp. 1883-1898
-
-
Johnston, J.1
Ward, C.2
Kopito, R.3
-
70
-
-
0037073747
-
Characterization of cytoplasmic alpha-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells
-
Lee H., and Lee S. Characterization of cytoplasmic alpha-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells. J Biol Chem 277 (2002) 48976-48983
-
(2002)
J Biol Chem
, vol.277
, pp. 48976-48983
-
-
Lee, H.1
Lee, S.2
-
71
-
-
0037033074
-
Parkin accumulation in aggresomes due to proteasome impairment
-
Junn E., Lee S., Suhr U., and Mouradian M. Parkin accumulation in aggresomes due to proteasome impairment. J Biol Chem 277 (2002) 47870-47877
-
(2002)
J Biol Chem
, vol.277
, pp. 47870-47877
-
-
Junn, E.1
Lee, S.2
Suhr, U.3
Mouradian, M.4
-
72
-
-
0035800097
-
Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease
-
Volles M., Lee S., Rochet J., Shtilerman M., Ding T., Kessler J., et al. Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease. Biochemistry 40 (2001) 7812-7819
-
(2001)
Biochemistry
, vol.40
, pp. 7812-7819
-
-
Volles, M.1
Lee, S.2
Rochet, J.3
Shtilerman, M.4
Ding, T.5
Kessler, J.6
-
73
-
-
0021680307
-
Uptake of MPP(+) by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP
-
Javitch J., and Snyder S. Uptake of MPP(+) by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP. Eur J Pharmacol 106 (1984) 455-456
-
(1984)
Eur J Pharmacol
, vol.106
, pp. 455-456
-
-
Javitch, J.1
Snyder, S.2
-
74
-
-
0030877835
-
Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter
-
Gainetdinov R., Fumagalli F., and Caron M. Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter. J Neurochem 69 (1997) 1322-1325
-
(1997)
J Neurochem
, vol.69
, pp. 1322-1325
-
-
Gainetdinov, R.1
Fumagalli, F.2
Caron, M.3
-
75
-
-
0032125186
-
Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter
-
Fumagalli F., Gainetdinov R., Valenzano K., and Caron M. Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter. J Neurosci 18 (1998) 4861-4869
-
(1998)
J Neurosci
, vol.18
, pp. 4861-4869
-
-
Fumagalli, F.1
Gainetdinov, R.2
Valenzano, K.3
Caron, M.4
-
76
-
-
0022515585
-
Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+
-
Ramsay R., Salach J., and Singer T. Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+. Biochem Biophys Res Commun 134 (1986) 743-748
-
(1986)
Biochem Biophys Res Commun
, vol.134
, pp. 743-748
-
-
Ramsay, R.1
Salach, J.2
Singer, T.3
-
77
-
-
0023093745
-
MPTP, MPP+ and mitochondrial function
-
Nicklas W., Youngster S., Kindt M., and Heikkila R. MPTP, MPP+ and mitochondrial function. Life Sci 40 (1987) 721-729
-
(1987)
Life Sci
, vol.40
, pp. 721-729
-
-
Nicklas, W.1
Youngster, S.2
Kindt, M.3
Heikkila, R.4
-
78
-
-
0030053169
-
Sulfonylurea-sensitive potassium current evoked by sodium-loading in rat midbrain dopamine neurons
-
Seutin V., Shen K., North R., and Johnson S. Sulfonylurea-sensitive potassium current evoked by sodium-loading in rat midbrain dopamine neurons. Neuroscience 71 (1996) 709-719
-
(1996)
Neuroscience
, vol.71
, pp. 709-719
-
-
Seutin, V.1
Shen, K.2
North, R.3
Johnson, S.4
-
79
-
-
0037101540
-
Stimulation-dependent regulation of secretory vesicle pH, volume, and quantal size
-
Pothos E., Mosharov E., Liu K., Setlik W., Baldini G., Gershon M., et al. Stimulation-dependent regulation of secretory vesicle pH, volume, and quantal size. J Physiol (Lond) 542 (2002) 453-476
-
(2002)
J Physiol (Lond)
, vol.542
, pp. 453-476
-
-
Pothos, E.1
Mosharov, E.2
Liu, K.3
Setlik, W.4
Baldini, G.5
Gershon, M.6
-
80
-
-
0027487511
-
Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity
-
Przedborski S., Jackson-Lewis V., Muthane U., Jiang H., Ferreira M., Naini A.-B., and Fahn S. Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity. Ann Neurol 34 (1993) 715-723
-
(1993)
Ann Neurol
, vol.34
, pp. 715-723
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Muthane, U.3
Jiang, H.4
Ferreira, M.5
Naini, A.-B.6
Fahn, S.7
-
81
-
-
0036310237
-
Inhibition of brain mitochondrial respiration by dopamine: involvement of H(2)O(2) and hydroxyl radicals but not glutathione-protein-mixed disulfides
-
Gluck M., Ehrhart J., Jayatilleke E., and Zeevalk G. Inhibition of brain mitochondrial respiration by dopamine: involvement of H(2)O(2) and hydroxyl radicals but not glutathione-protein-mixed disulfides. J Neurochem 82 (2002) 66-74
-
(2002)
J Neurochem
, vol.82
, pp. 66-74
-
-
Gluck, M.1
Ehrhart, J.2
Jayatilleke, E.3
Zeevalk, G.4
-
82
-
-
0035144650
-
Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease
-
Przedborski S., Chen Q., Vila M., Giasson B., Djaldatti R., Vukosavic S., et al. Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease. J Neurochem 76 (2001) 637-640
-
(2001)
J Neurochem
, vol.76
, pp. 637-640
-
-
Przedborski, S.1
Chen, Q.2
Vila, M.3
Giasson, B.4
Djaldatti, R.5
Vukosavic, S.6
-
83
-
-
0035824528
-
Nitration and inactivation of tyrosine hydroxylase by peroxynitrite
-
Blanchard-Fillion B., Souza J., Friel T., Jiang G., Vrana K., Sharov V., et al. Nitration and inactivation of tyrosine hydroxylase by peroxynitrite. J Biol Chem 276 (2001) 46017-46023
-
(2001)
J Biol Chem
, vol.276
, pp. 46017-46023
-
-
Blanchard-Fillion, B.1
Souza, J.2
Friel, T.3
Jiang, G.4
Vrana, K.5
Sharov, V.6
-
84
-
-
0019812302
-
Magnitude and duration of hyperactivity following neonatal 6-hydroxydopamine is related to the extent of brain dopamine depletion
-
Miller F., Heffner T., Kotake C., and Seiden L. Magnitude and duration of hyperactivity following neonatal 6-hydroxydopamine is related to the extent of brain dopamine depletion. Brain Res 229 (1981) 123-132
-
(1981)
Brain Res
, vol.229
, pp. 123-132
-
-
Miller, F.1
Heffner, T.2
Kotake, C.3
Seiden, L.4
-
85
-
-
0028329215
-
Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress
-
Cubells J., Rayport S., Rajendran G., and Sulzer D. Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress. J Neurosci 14 (1994) 2260-2271
-
(1994)
J Neurosci
, vol.14
, pp. 2260-2271
-
-
Cubells, J.1
Rayport, S.2
Rajendran, G.3
Sulzer, D.4
-
86
-
-
0028947076
-
Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: impact of methamphetamine
-
Giovanni A., Liang L., Hastings T., and Zigmond M. Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: impact of methamphetamine. J Neurochem 64 (1995) 1819-1825
-
(1995)
J Neurochem
, vol.64
, pp. 1819-1825
-
-
Giovanni, A.1
Liang, L.2
Hastings, T.3
Zigmond, M.4
-
87
-
-
0025647857
-
Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action
-
Sulzer D., and Rayport S. Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action. Neuron 5 (1990) 797-808
-
(1990)
Neuron
, vol.5
, pp. 797-808
-
-
Sulzer, D.1
Rayport, S.2
-
88
-
-
0011738348
-
Dopamine-induced toxicity and quinone modification of proteins: implications for Parkinson's disease
-
Creveling C. (Ed), F. P. Graham, Johnson City, TN
-
Hastings T., and Berman S. Dopamine-induced toxicity and quinone modification of proteins: implications for Parkinson's disease. In: Creveling C. (Ed). Role of catechol quinone species in cellular toxicity (1999), F. P. Graham, Johnson City, TN 69-89
-
(1999)
Role of catechol quinone species in cellular toxicity
, pp. 69-89
-
-
Hastings, T.1
Berman, S.2
-
89
-
-
0001672745
-
Intraneuronal dopamine-quinone synthesis: a review
-
Sulzer D., and Zecca L. Intraneuronal dopamine-quinone synthesis: a review. Neurotoxicity Res 1 (2000) 181-195
-
(2000)
Neurotoxicity Res
, vol.1
, pp. 181-195
-
-
Sulzer, D.1
Zecca, L.2
-
90
-
-
0018095085
-
Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones
-
Graham D. Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol Pharmacol 14 (1978) 633-643
-
(1978)
Mol Pharmacol
, vol.14
, pp. 633-643
-
-
Graham, D.1
-
91
-
-
0035112815
-
Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter
-
Whitehead R., Ferrer J., Javitch J., and Justice J. Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter. J Neurochem 76 (2001) 1242-1251
-
(2001)
J Neurochem
, vol.76
, pp. 1242-1251
-
-
Whitehead, R.1
Ferrer, J.2
Javitch, J.3
Justice, J.4
-
92
-
-
0034624017
-
The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium (MPP+) triggers intracellular dopamine oxidation: a novel mechanism of toxicity
-
Lotharius J., and O'Malley K. The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium (MPP+) triggers intracellular dopamine oxidation: a novel mechanism of toxicity. J Biol Chem 275 (2000) 38581-38588
-
(2000)
J Biol Chem
, vol.275
, pp. 38581-38588
-
-
Lotharius, J.1
O'Malley, K.2
-
93
-
-
0034882387
-
Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment
-
Davidson C., Gow A., Lee T., and Ellinwood E. Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment. Brain Res Brain Res Rev 36 (2001) 1-22
-
(2001)
Brain Res Brain Res Rev
, vol.36
, pp. 1-22
-
-
Davidson, C.1
Gow, A.2
Lee, T.3
Ellinwood, E.4
-
94
-
-
0031079599
-
S-Methylthiocitrulline, a neuronal nitric oxide synthase inhibitor, protects against malonate and MPTP neurotoxicity
-
Matthews R., Yang L., and Beal M. S-Methylthiocitrulline, a neuronal nitric oxide synthase inhibitor, protects against malonate and MPTP neurotoxicity. Exp Neurol 143 (1997) 282-286
-
(1997)
Exp Neurol
, vol.143
, pp. 282-286
-
-
Matthews, R.1
Yang, L.2
Beal, M.3
-
95
-
-
0036326167
-
The neuromelanin of human substantia nigra and its interaction with metals
-
Zecca L., Tampellini D., Gatti A., Crippa R., Eisner M., Sulzer D., et al. The neuromelanin of human substantia nigra and its interaction with metals. J Neural Transm 109 (2002) 663-672
-
(2002)
J Neural Transm
, vol.109
, pp. 663-672
-
-
Zecca, L.1
Tampellini, D.2
Gatti, A.3
Crippa, R.4
Eisner, M.5
Sulzer, D.6
-
96
-
-
0034776216
-
Brain iron pathways and their relevance to Parkinson's disease
-
Berg D., Gerlach M., Youdim M., Double K., Zecca L., Riederer P., et al. Brain iron pathways and their relevance to Parkinson's disease. J Neurochem 79 (2001) 225-236
-
(2001)
J Neurochem
, vol.79
, pp. 225-236
-
-
Berg, D.1
Gerlach, M.2
Youdim, M.3
Double, K.4
Zecca, L.5
Riederer, P.6
-
97
-
-
12944305793
-
Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles
-
Sulzer D., Bogulavsky J., Larsen K., Behr G., Karatekin E., Kleinman M., et al. Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles. Proc Natl Acad Sci USA 97 (2000) 11869-11874
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11869-11874
-
-
Sulzer, D.1
Bogulavsky, J.2
Larsen, K.3
Behr, G.4
Karatekin, E.5
Kleinman, M.6
-
98
-
-
0036066121
-
Autophagy in neurons: a review
-
Larsen K., and Sulzer D. Autophagy in neurons: a review. Histol Histopathol 17 (2002) 897-908
-
(2002)
Histol Histopathol
, vol.17
, pp. 897-908
-
-
Larsen, K.1
Sulzer, D.2
-
99
-
-
0026713852
-
A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter
-
Liu Y., Peter D., Roghani A., Schuldiner S., Prive G., Eisenberg D., et al. A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter. Cell 70 (1992) 539-551
-
(1992)
Cell
, vol.70
, pp. 539-551
-
-
Liu, Y.1
Peter, D.2
Roghani, A.3
Schuldiner, S.4
Prive, G.5
Eisenberg, D.6
-
100
-
-
0034307584
-
Synaptic vesicle transporter expression regulates vesicle phenotype and quantal size
-
Pothos E., Larsen K., Krantz D., Liu Y.-J., Edwards R., and Sulzer D. Synaptic vesicle transporter expression regulates vesicle phenotype and quantal size. J Neurosci 20 (2000) 7297-7306
-
(2000)
J Neurosci
, vol.20
, pp. 7297-7306
-
-
Pothos, E.1
Larsen, K.2
Krantz, D.3
Liu, Y.-J.4
Edwards, R.5
Sulzer, D.6
-
101
-
-
0037109770
-
Methamphetamine-induced degeneration of dopaminergic neurons occurs via autophagy triggered by elevated cytosolic dopamine
-
Larsen K., Fon E., LaVoie M., Hastings T., Edwards R., and Sulzer D. Methamphetamine-induced degeneration of dopaminergic neurons occurs via autophagy triggered by elevated cytosolic dopamine. J Neurosci 22 (2002) 8951-8960
-
(2002)
J Neurosci
, vol.22
, pp. 8951-8960
-
-
Larsen, K.1
Fon, E.2
LaVoie, M.3
Hastings, T.4
Edwards, R.5
Sulzer, D.6
-
102
-
-
0033118563
-
Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice
-
Fumagalli F., Gainetdinov R., Wang Y., Valenzano K., Miller G., and Caron M. Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice. J Neurosci 19 (1999) 2424-2431
-
(1999)
J Neurosci
, vol.19
, pp. 2424-2431
-
-
Fumagalli, F.1
Gainetdinov, R.2
Wang, Y.3
Valenzano, K.4
Miller, G.5
Caron, M.6
-
103
-
-
0031959343
-
Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice
-
Gainetdinov R., Fumagalli F., Wang Y., Jones S., Levey A., Miller G., et al. Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice. J Neurochem 70 (1998) 1973-1978
-
(1998)
J Neurochem
, vol.70
, pp. 1973-1978
-
-
Gainetdinov, R.1
Fumagalli, F.2
Wang, Y.3
Jones, S.4
Levey, A.5
Miller, G.6
-
104
-
-
0037426917
-
Pathways to Parkinsonism
-
Cookson M. Pathways to Parkinsonism. Neuron 37 (2003) 7-10
-
(2003)
Neuron
, vol.37
, pp. 7-10
-
-
Cookson, M.1
-
105
-
-
0037468831
-
Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by pael-R in Drosophila
-
Yang Y., Nishimura I., Imai Y., Takahashi R., and Lu B. Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by pael-R in Drosophila. Neuron 37 (2003) 911-924
-
(2003)
Neuron
, vol.37
, pp. 911-924
-
-
Yang, Y.1
Nishimura, I.2
Imai, Y.3
Takahashi, R.4
Lu, B.5
-
106
-
-
0037189591
-
Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synuclein
-
Ribeiro C., Carneiro K., Ross C., Menezes J., and Engelender S. Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synuclein. J Biol Chem 277 (2002) 23927-23933
-
(2002)
J Biol Chem
, vol.277
, pp. 23927-23933
-
-
Ribeiro, C.1
Carneiro, K.2
Ross, C.3
Menezes, J.4
Engelender, S.5
-
107
-
-
0035894855
-
Expression of A53T mutant, but not wild-type, α-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death
-
Stefanis L., Larsen K., Rideout H., Sulzer D., and Greene L. Expression of A53T mutant, but not wild-type, α-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death. J Neurosci 21 (2001) 9549-9560
-
(2001)
J Neurosci
, vol.21
, pp. 9549-9560
-
-
Stefanis, L.1
Larsen, K.2
Rideout, H.3
Sulzer, D.4
Greene, L.5
-
108
-
-
0031883733
-
Lysosomes, a meeting point of proteins, chaperones, and proteases
-
Cuervo A., and Dice J. Lysosomes, a meeting point of proteins, chaperones, and proteases. J Mol Med 76 (1998) 6-12
-
(1998)
J Mol Med
, vol.76
, pp. 6-12
-
-
Cuervo, A.1
Dice, J.2
-
109
-
-
0026504821
-
Calbindin-D28K-containing neurons in animal models of neurodegeneration: possible protection from excitotoxicity
-
Iacopino A., Christakos S., German D., Sonsalla P., and Altar C. Calbindin-D28K-containing neurons in animal models of neurodegeneration: possible protection from excitotoxicity. Brain Res Mol Brain Res 13 (1992) 251-261
-
(1992)
Brain Res Mol Brain Res
, vol.13
, pp. 251-261
-
-
Iacopino, A.1
Christakos, S.2
German, D.3
Sonsalla, P.4
Altar, C.5
-
110
-
-
0029051873
-
Differential expression of two vesicular monoamine transporters
-
Peter D., Liu Y., Sternini C., de Giorgio R., Brecha N., and Edwards R. Differential expression of two vesicular monoamine transporters. J Neurosci 15 (1995) 6179-6188
-
(1995)
J Neurosci
, vol.15
, pp. 6179-6188
-
-
Peter, D.1
Liu, Y.2
Sternini, C.3
de Giorgio, R.4
Brecha, N.5
Edwards, R.6
-
111
-
-
0034012173
-
In vitro studies of striatal vesicles containing the vesicular monoamine transporter (VMAT2): rat versus mouse differences in sequestration of 1-methyl-4-phenylpyridinium
-
Staal R., Hogan K., Liang C., German D., and Sonsalla P. In vitro studies of striatal vesicles containing the vesicular monoamine transporter (VMAT2): rat versus mouse differences in sequestration of 1-methyl-4-phenylpyridinium. J Pharmacol Exp Ther 293 (2000) 329-335
-
(2000)
J Pharmacol Exp Ther
, vol.293
, pp. 329-335
-
-
Staal, R.1
Hogan, K.2
Liang, C.3
German, D.4
Sonsalla, P.5
-
112
-
-
0033570331
-
The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wvGirk2 and K-ATP channels
-
Liss B., Neu A., and Roeper J. The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wvGirk2 and K-ATP channels. J Neurosci 19 (1999) 8839-8848
-
(1999)
J Neurosci
, vol.19
, pp. 8839-8848
-
-
Liss, B.1
Neu, A.2
Roeper, J.3
-
113
-
-
0031783647
-
Glial cell line-derived neurotrophic growth factor inhibits apoptotic death of postnatal substantia nigra dopamine neurons in primary culture
-
Burke R., Antonelli M., and Sulzer D. Glial cell line-derived neurotrophic growth factor inhibits apoptotic death of postnatal substantia nigra dopamine neurons in primary culture. J Neurochem 71 (1998) 517-525
-
(1998)
J Neurochem
, vol.71
, pp. 517-525
-
-
Burke, R.1
Antonelli, M.2
Sulzer, D.3
-
114
-
-
0033678297
-
Apoptosis as a general cell death pathway in neurodegenerative diseases
-
Offen D., Elkon H., and Melamed E. Apoptosis as a general cell death pathway in neurodegenerative diseases. J Neural Transm Suppl 58 (2000) 153-166
-
(2000)
J Neural Transm Suppl
, vol.58
, pp. 153-166
-
-
Offen, D.1
Elkon, H.2
Melamed, E.3
-
115
-
-
0001485756
-
MPTP: a review of its mechanisms of neurotoxicity
-
Przedborksi S., and Vila M. MPTP: a review of its mechanisms of neurotoxicity. Clin Neurosci Res 1 (2001) 407-418
-
(2001)
Clin Neurosci Res
, vol.1
, pp. 407-418
-
-
Przedborksi, S.1
Vila, M.2
-
116
-
-
0034904508
-
The role of glial cells in Parkinson's disease
-
Vila M., Jackson-Lewis V., Guegan C., Wu D., Teismann P., Choi D., et al. The role of glial cells in Parkinson's disease. Curr Opin Neurol 14 (2001) 483-489
-
(2001)
Curr Opin Neurol
, vol.14
, pp. 483-489
-
-
Vila, M.1
Jackson-Lewis, V.2
Guegan, C.3
Wu, D.4
Teismann, P.5
Choi, D.6
-
117
-
-
0037366093
-
Activation of microglia by human neuromelanin is NF-κB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease
-
Wilms H., Rosenstiel P., Sievers J., Deuschl G., Zecca L., and Lucius R. Activation of microglia by human neuromelanin is NF-κB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease. FASEB J 17 (2003) 500-502
-
(2003)
FASEB J
, vol.17
, pp. 500-502
-
-
Wilms, H.1
Rosenstiel, P.2
Sievers, J.3
Deuschl, G.4
Zecca, L.5
Lucius, R.6
-
118
-
-
0038641723
-
Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration
-
Teismann P., Tieu K., Choi D., Wu D., Naini A., Hunot S., et al. Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration. Proc Natl Acad Sci USA 100 (2003) 5473-5478
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5473-5478
-
-
Teismann, P.1
Tieu, K.2
Choi, D.3
Wu, D.4
Naini, A.5
Hunot, S.6
-
119
-
-
0024456653
-
Effect of deprenyl on the progression of disability in early Parkinson's disease
-
Parkinson Study Group. Effect of deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med 321 (1989) 1364-1371
-
(1989)
N Engl J Med
, vol.321
, pp. 1364-1371
-
-
Parkinson Study Group1
-
120
-
-
0027530638
-
Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease
-
Parkinson Study Group. Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med 328 (1993) 176-183
-
(1993)
N Engl J Med
, vol.328
, pp. 176-183
-
-
Parkinson Study Group1
-
121
-
-
0026596575
-
Selegiline as initial treatment in de novo parkinsonian patients
-
Myllyla V., Sotaniemi K., Vuorinen J., and Heinonen E. Selegiline as initial treatment in de novo parkinsonian patients. Neurology 42 (1992) 339-343
-
(1992)
Neurology
, vol.42
, pp. 339-343
-
-
Myllyla, V.1
Sotaniemi, K.2
Vuorinen, J.3
Heinonen, E.4
-
122
-
-
0345019854
-
Selegiline delays the onset of disability in de novo parkinsonian patients. Swedish Parkinson Study Group
-
Palhagen S., Heinonen E., Hagglund J., Kaugesaar T., Kontants H., Maki-Ikola O., et al. Selegiline delays the onset of disability in de novo parkinsonian patients. Swedish Parkinson Study Group. Neurology 51 (1998) 520-525
-
(1998)
Neurology
, vol.51
, pp. 520-525
-
-
Palhagen, S.1
Heinonen, E.2
Hagglund, J.3
Kaugesaar, T.4
Kontants, H.5
Maki-Ikola, O.6
-
123
-
-
0035954349
-
Freezing of gait in PD: prospective assessment in the DATATOP cohort
-
Giladi N., McDermott M., Fahn S., Przedborski S., Jankovic J., Stern M., et al. Freezing of gait in PD: prospective assessment in the DATATOP cohort. Neurology 56 (2001) 1712-1721
-
(2001)
Neurology
, vol.56
, pp. 1712-1721
-
-
Giladi, N.1
McDermott, M.2
Fahn, S.3
Przedborski, S.4
Jankovic, J.5
Stern, M.6
-
124
-
-
0036231440
-
Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial
-
Shoulson I., Oakes D., Fahn S., Lang A., Langston J., LeWitt P., et al. Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial. Ann Neurol 51 (2002) 604-612
-
(2002)
Ann Neurol
, vol.51
, pp. 604-612
-
-
Shoulson, I.1
Oakes, D.2
Fahn, S.3
Lang, A.4
Langston, J.5
LeWitt, P.6
-
125
-
-
0031711224
-
Excitotoxicity and nitric oxide in Parkinson's disease pathogenesis
-
Beal M. Excitotoxicity and nitric oxide in Parkinson's disease pathogenesis. Ann Neurol 44 (1998) S110-S114
-
(1998)
Ann Neurol
, vol.44
-
-
Beal, M.1
-
126
-
-
0029081625
-
Riluzole prevents MPTP-induced parkinsonism in the rhesus monkey: a pilot study
-
Benazzouz A., Boraud T., Dubedat P., Boireau A., Stutzmann J., and Gross C. Riluzole prevents MPTP-induced parkinsonism in the rhesus monkey: a pilot study. Eur J Pharmacol 284 (1995) 299-307
-
(1995)
Eur J Pharmacol
, vol.284
, pp. 299-307
-
-
Benazzouz, A.1
Boraud, T.2
Dubedat, P.3
Boireau, A.4
Stutzmann, J.5
Gross, C.6
-
127
-
-
0030271253
-
Neuroprotective effects of riluzole on a model of Parkinson's disease in the rat
-
Barneoud P., Mazadier M., Miquet J., Parmentier S., Dubedat P., Doble A., et al. Neuroprotective effects of riluzole on a model of Parkinson's disease in the rat. Neuroscience 74 (1996) 971-983
-
(1996)
Neuroscience
, vol.74
, pp. 971-983
-
-
Barneoud, P.1
Mazadier, M.2
Miquet, J.3
Parmentier, S.4
Dubedat, P.5
Doble, A.6
-
128
-
-
0034056425
-
The protective effect of riluzole in the MPTP model of Parkinson's disease in mice is not due to a decrease in MPP(+) accumulation
-
Boireau A., Dubedat P., Bordier F., Imperato A., and Moussaoui S. The protective effect of riluzole in the MPTP model of Parkinson's disease in mice is not due to a decrease in MPP(+) accumulation. Neuropharmacology 39 (2000) 1016-1020
-
(2000)
Neuropharmacology
, vol.39
, pp. 1016-1020
-
-
Boireau, A.1
Dubedat, P.2
Bordier, F.3
Imperato, A.4
Moussaoui, S.5
-
129
-
-
0036368298
-
Neuroprotective effect of riluzole in a primate model of Parkinson's disease: behavioral and histological evidence
-
Obinu M., Reibaud M., Blanchard V., Moussaoui S., and Imperato A. Neuroprotective effect of riluzole in a primate model of Parkinson's disease: behavioral and histological evidence. Mov Disord 17 (2002) 13-19
-
(2002)
Mov Disord
, vol.17
, pp. 13-19
-
-
Obinu, M.1
Reibaud, M.2
Blanchard, V.3
Moussaoui, S.4
Imperato, A.5
-
130
-
-
0036164536
-
A double-blind, placebo-controlled and longitudinal study of riluzole in early Parkinson's disease
-
Jankovic J., and Hunter C. A double-blind, placebo-controlled and longitudinal study of riluzole in early Parkinson's disease. Parkinsonism Relat Disord 8 (2002) 271-276
-
(2002)
Parkinsonism Relat Disord
, vol.8
, pp. 271-276
-
-
Jankovic, J.1
Hunter, C.2
-
131
-
-
34147095927
-
Effect of riluzole on Parkinson's disease progression: a double-blind placebo-controlled study
-
Rascol O., Olanow W., Brooks D., Koch G., Truffinet P., and Bejuit R. Effect of riluzole on Parkinson's disease progression: a double-blind placebo-controlled study. Neurology 60 Suppl 1 (2003) A288
-
(2003)
Neurology
, vol.60
, Issue.SUPPL. 1
-
-
Rascol, O.1
Olanow, W.2
Brooks, D.3
Koch, G.4
Truffinet, P.5
Bejuit, R.6
-
132
-
-
0032100808
-
Presynaptic recording of quanta from midbrain dopamine neurons and modulation of the quantal size
-
Pothos E., Davila V., and Sulzer D. Presynaptic recording of quanta from midbrain dopamine neurons and modulation of the quantal size. J Neurosci 18 (1998) 4106-4118
-
(1998)
J Neurosci
, vol.18
, pp. 4106-4118
-
-
Pothos, E.1
Davila, V.2
Sulzer, D.3
-
133
-
-
13344277993
-
Functional recovery in parkinsonian monkeys treated with GDNF
-
Gash D., Zhang Z., Ovadia A., Cass W., Yi A., Simmerman L., et al. Functional recovery in parkinsonian monkeys treated with GDNF. Nature 21 (1996) 252-255
-
(1996)
Nature
, vol.21
, pp. 252-255
-
-
Gash, D.1
Zhang, Z.2
Ovadia, A.3
Cass, W.4
Yi, A.5
Simmerman, L.6
-
134
-
-
0036787532
-
Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys
-
Grondin R., Zhang Z., Yi A., Cass W., Maswood N., Andersen A., et al. Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys. Brain 125 (2002) 2191-2201
-
(2002)
Brain
, vol.125
, pp. 2191-2201
-
-
Grondin, R.1
Zhang, Z.2
Yi, A.3
Cass, W.4
Maswood, N.5
Andersen, A.6
-
135
-
-
0037435511
-
Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
-
Nutt J., Burchiel K., Comella C., Jankovic J., Lang A., Laws Jr. E., et al. Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD. Neurology 60 (2003) 69-73
-
(2003)
Neurology
, vol.60
, pp. 69-73
-
-
Nutt, J.1
Burchiel, K.2
Comella, C.3
Jankovic, J.4
Lang, A.5
Laws Jr., E.6
-
136
-
-
0000543509
-
Intraparenchymal putaminal administration of glial-derived neurotrophic factor in the treatment of advanced Parkinson's disease
-
Gill S., Patel N., O'Sullivan K., Brooks D., Hotton G., Svendsen C., et al. Intraparenchymal putaminal administration of glial-derived neurotrophic factor in the treatment of advanced Parkinson's disease. Neurology 58 Suppl 3 (2002) A241
-
(2002)
Neurology
, vol.58
, Issue.SUPPL. 3
-
-
Gill, S.1
Patel, N.2
O'Sullivan, K.3
Brooks, D.4
Hotton, G.5
Svendsen, C.6
-
137
-
-
0034721690
-
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
-
Kordower J., Emborg M., Bloch J., Ma S., Chu Y., Leventhal L., et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 290 (2000) 767-773
-
(2000)
Science
, vol.290
, pp. 767-773
-
-
Kordower, J.1
Emborg, M.2
Bloch, J.3
Ma, S.4
Chu, Y.5
Leventhal, L.6
-
138
-
-
12644257556
-
Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models
-
Steiner J., Hamilton G., Ross D., Valentine H., Guo H., Connolly M., et al. Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models. Proc Natl Acad Sci USA 94 (1997) 2019-2024
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2019-2024
-
-
Steiner, J.1
Hamilton, G.2
Ross, D.3
Valentine, H.4
Guo, H.5
Connolly, M.6
-
139
-
-
0034998137
-
Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons
-
Guo X., Dawson V., and Dawson T. Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons. Eur J Neurosci 13 (2001) 1683-1693
-
(2001)
Eur J Neurosci
, vol.13
, pp. 1683-1693
-
-
Guo, X.1
Dawson, V.2
Dawson, T.3
-
140
-
-
0035910371
-
Immunosuppressive and non-immunosuppressive immunophilin ligands improve H(2)O(2)-induced cell damage by increasing glutathione levels in NG108-15 cells
-
Tanaka K., Fujita N., Yoshioka M., and Ogawa N. Immunosuppressive and non-immunosuppressive immunophilin ligands improve H(2)O(2)-induced cell damage by increasing glutathione levels in NG108-15 cells. Brain Res 889 (2001) 225-228
-
(2001)
Brain Res
, vol.889
, pp. 225-228
-
-
Tanaka, K.1
Fujita, N.2
Yoshioka, M.3
Ogawa, N.4
-
141
-
-
0037087049
-
GPI1046 prevents dopaminergic dysfunction by activating glutathione system in the mouse striatum
-
Tanaka K., Yoshioka M., Miyazaki I., Fujita N., and Ogawa N. GPI1046 prevents dopaminergic dysfunction by activating glutathione system in the mouse striatum. Neurosci Lett 321 (2002) 45-48
-
(2002)
Neurosci Lett
, vol.321
, pp. 45-48
-
-
Tanaka, K.1
Yoshioka, M.2
Miyazaki, I.3
Fujita, N.4
Ogawa, N.5
-
142
-
-
0032889368
-
Analysis of the neurotrophic effects of GPI-1046 on neuron survival and regeneration in culture and in vivo
-
Harper S., Bilsland J., Young L., Bristow L., Boyce S., Mason G., et al. Analysis of the neurotrophic effects of GPI-1046 on neuron survival and regeneration in culture and in vivo. Neuroscience 88 (1999) 257-267
-
(1999)
Neuroscience
, vol.88
, pp. 257-267
-
-
Harper, S.1
Bilsland, J.2
Young, L.3
Bristow, L.4
Boyce, S.5
Mason, G.6
-
143
-
-
0035896266
-
Failure of GPI compounds to display neurotrophic activity in vitro and in vivo
-
Bocquet A., Lorent G., Fuks B., Grimee R., Talaga P., Daliers J., et al. Failure of GPI compounds to display neurotrophic activity in vitro and in vivo. Eur J Pharmacol 415 (2001) 173-180
-
(2001)
Eur J Pharmacol
, vol.415
, pp. 173-180
-
-
Bocquet, A.1
Lorent, G.2
Fuks, B.3
Grimee, R.4
Talaga, P.5
Daliers, J.6
-
144
-
-
0035123909
-
Systemic administration of the immunophilin ligand GPI 1046 in MPTP-treated monkeys
-
Emborg M., Shin P., Roitberg B., Sramek J., Chu Y., Stebbins G., et al. Systemic administration of the immunophilin ligand GPI 1046 in MPTP-treated monkeys. Exp Neurol 168 (2001) 171-182
-
(2001)
Exp Neurol
, vol.168
, pp. 171-182
-
-
Emborg, M.1
Shin, P.2
Roitberg, B.3
Sramek, J.4
Chu, Y.5
Stebbins, G.6
-
145
-
-
0036939396
-
The immunophilin ligand GPI-1046 does not have neuroregenerative effects in MPTP-treated monkeys
-
Eberling J., Pivirotto P., Bringas J., Steiner J., Kordower J., Chu Y., et al. The immunophilin ligand GPI-1046 does not have neuroregenerative effects in MPTP-treated monkeys. Exp Neurol 178 (2002) 236-242
-
(2002)
Exp Neurol
, vol.178
, pp. 236-242
-
-
Eberling, J.1
Pivirotto, P.2
Bringas, J.3
Steiner, J.4
Kordower, J.5
Chu, Y.6
-
146
-
-
0025640845
-
Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease
-
Schapira A., Mann V., Cooper J., Dexter D., Daniel S., Jenner P., et al. Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease. J Neurochem 55 (1990) 2142-2145
-
(1990)
J Neurochem
, vol.55
, pp. 2142-2145
-
-
Schapira, A.1
Mann, V.2
Cooper, J.3
Dexter, D.4
Daniel, S.5
Jenner, P.6
-
147
-
-
0030612117
-
Coenzyme Q(10) levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects
-
Shults C., Haas R., Passov D., and Beal M. Coenzyme Q(10) levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann Neurol 42 (1997) 261-264
-
(1997)
Ann Neurol
, vol.42
, pp. 261-264
-
-
Shults, C.1
Haas, R.2
Passov, D.3
Beal, M.4
-
148
-
-
0001115172
-
Serum coenzyme Q10 level in Parkinson syndrome
-
Folkers K., Littarru G., and Yamagami T. (Eds), Elsevier Science, New York
-
Matsubara T., Azuma T., Yoshida S., and Yamagami T. Serum coenzyme Q10 level in Parkinson syndrome. In: Folkers K., Littarru G., and Yamagami T. (Eds). Biomedical and clinical aspects of coenzyme Q10 (1991), Elsevier Science, New York 159-166
-
(1991)
Biomedical and clinical aspects of coenzyme Q10
, pp. 159-166
-
-
Matsubara, T.1
Azuma, T.2
Yoshida, S.3
Yamagami, T.4
-
149
-
-
0032555066
-
Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects
-
Matthews R., Yang L., Browne S., Baik M., and Beal M. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci USA 95 (1998) 8892-8897
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8892-8897
-
-
Matthews, R.1
Yang, L.2
Browne, S.3
Baik, M.4
Beal, M.5
-
150
-
-
0036771852
-
Effects of coenzyme Q(10) in early Parkinson disease - Evidence of slowing of the functional decline
-
Shults C., Oakes D., Kieburtz K., Beal M., Haas R., Plumb S., et al. Effects of coenzyme Q(10) in early Parkinson disease - Evidence of slowing of the functional decline. Arch Neurol 59 (2002) 1541-1550
-
(2002)
Arch Neurol
, vol.59
, pp. 1541-1550
-
-
Shults, C.1
Oakes, D.2
Kieburtz, K.3
Beal, M.4
Haas, R.5
Plumb, S.6
-
151
-
-
0037379314
-
Bioenergetic approaches for neuroprotection in Parkinson's disease
-
discussion S47-S48
-
Beal M. Bioenergetic approaches for neuroprotection in Parkinson's disease. Ann Neurol 53 Suppl 3 (2003) S39-S47 discussion S47-S48
-
(2003)
Ann Neurol
, vol.53
, Issue.SUPPL. 3
-
-
Beal, M.1
-
152
-
-
0035807904
-
Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease
-
Du Y., Ma Z., Lin S., Dodel R., Gao F., Bales K., et al. Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease. Proc Natl Acad Sci USA 98 (2001) 14669-14674
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 14669-14674
-
-
Du, Y.1
Ma, Z.2
Lin, S.3
Dodel, R.4
Gao, F.5
Bales, K.6
-
153
-
-
0036522967
-
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
-
Wu D., Jackson-Lewis V., Vila M., Tieu K., Teismann P., Vadseth C., et al. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J Neurosci 22 (2002) 1763-1771
-
(2002)
J Neurosci
, vol.22
, pp. 1763-1771
-
-
Wu, D.1
Jackson-Lewis, V.2
Vila, M.3
Tieu, K.4
Teismann, P.5
Vadseth, C.6
-
154
-
-
0027496801
-
Selegiline can mediate neuronal rescue rather than neuronal protection
-
Tatton W. Selegiline can mediate neuronal rescue rather than neuronal protection. Mov Disord 8 (1993) S20-S30
-
(1993)
Mov Disord
, vol.8
-
-
Tatton, W.1
-
155
-
-
0033659663
-
CGP 3466 protects dopaminergic neurons in lesion models of Parkinson's disease
-
Waldmeier P., Spooren W., and Hengerer B. CGP 3466 protects dopaminergic neurons in lesion models of Parkinson's disease. Naunyn Schmiedebergs Arch Pharmacol 362 (2000) 526-537
-
(2000)
Naunyn Schmiedebergs Arch Pharmacol
, vol.362
, pp. 526-537
-
-
Waldmeier, P.1
Spooren, W.2
Hengerer, B.3
-
156
-
-
0021137683
-
Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism
-
Markey S., Johannessen J., Chiueh C., Burns R., and Herkenham M. Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism. Nature 311 (1984) 464-467
-
(1984)
Nature
, vol.311
, pp. 464-467
-
-
Markey, S.1
Johannessen, J.2
Chiueh, C.3
Burns, R.4
Herkenham, M.5
-
157
-
-
0000340348
-
Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity
-
Javitch J., D'Amato R., Strittmatter S., and Snyder S. Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. Proc Natl Acad Sci USA 82 (1985) 2173-2177
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 2173-2177
-
-
Javitch, J.1
D'Amato, R.2
Strittmatter, S.3
Snyder, S.4
-
158
-
-
0033807212
-
Images. Les corps et prolongements de Lewy
-
Duyckaerts C. Images. Les corps et prolongements de Lewy. Rev Neurol (Paris) 156 (2000) 800-801
-
(2000)
Rev Neurol (Paris)
, vol.156
, pp. 800-801
-
-
Duyckaerts, C.1
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