Inhibition of brain mitochondrial respiration by dopamine: Involvement of H2O2 and hydroxyl radicals but not glutathione-protein-mixed disulfides

Journal of Neurochemistry

Volumn 82, Issue 1, 2002, Pages 66-74

  Gluck, Martin ^a   Ehrhart, Julie ^b   Jayatilleke, Elizabeth ^a   Zeevalk, Gail D ^b  

^a Department of Psychiatry   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Dopamine; Glutathione; Glutathione protein mixed disulfides; Mitochondria; Parkinson's disease; Peroxide

Indexed keywords

CLORGYLINE; DEFEROXAMINE; DOPAMINE; GLUTAMIC ACID; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MALIC ACID; PARGYLINE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; ROTENONE; SUCCINATE DEHYDROGENASE; SUCCINIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CONTROLLED STUDY; DISSOCIATION; DOPAMINERGIC SYSTEM; ELECTRON TRANSPORT; ENZYME ACTIVITY; FEMALE; FREEZING; IC 50; INHIBITION KINETICS; MITOCHONDRIAL RESPIRATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

ANIMALS; BRAIN; BRAIN CHEMISTRY; CELL RESPIRATION; DISULFIDES; DOPAMINE; FEMALE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; IRON CHELATING AGENTS; MITOCHONDRIA; MONOAMINE OXIDASE; OXIDANTS; OXYGEN CONSUMPTION; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; SUS SCROFA;

EID: 0036310237     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00938.x     Document Type: Article

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