Preservation of midbrain catecholaminergic neurons in very old human subjects

Brain

Volumn 123, Issue 2, 2000, Pages 366-373

  Kubis, N ^a   Faucheux, B A ^a   Ransmayr, G ^e   Damier, P ^a   Duyckaerts, C ^b   Henin, D ^c   Forette, B ^d   Le Charpentier, Y ^b   Hauw, J J ^b   Agid, Y ^a   Hirsch, E C ^a,b  

^a INSERM   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^c BICHAT HOSPITAL   (France)

^d Versailles Saint Quentin en Yvelines University   (France)

^e MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Ageing; Human; Substantia nigra; Tyrosine hydroxylase

Indexed keywords

TYROSINE 3 MONOOXYGENASE;

ADULT; AGED; AGING; ARTICLE; BRAIN STEM; CATECHOLAMINE NERVE CELL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GRAY MATTER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LOCUS CERULEUS; MALE; MESENCEPHALON; NERVE DEGENERATION; NORMAL HUMAN; PARKINSON DISEASE; PONS; PRIORITY JOURNAL; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM;

EID: 0033959077     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/123.2.366     Document Type: Article

References (34)

1. Abercrombie M. Estimation of nuclear population from microtome sections. Anat Rec 1946; 94: 239-47.
2. Brooks DJ, Ibanez V, Sawle GV, Quinn N, Lees AJ, Mathias CJ, et al. Differing patterns of striatal 18F-dopa uptake in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Ann Neurol 1990; 28: 547-55.
3. Calne DB, Peppard RF. Aging of the nigrostriatal pathway in humans. Can J Neurol Sci 1987; 14 (3 Suppl): 424-7.
4. Carey JR, Liedo P, Orozco D, Vaupel JW. Slowing of mortality rates at older ages in large medfly cohorts. Science 1992; 258: 457-61.
5. Chan-Palay V, Asan E. Quantitation of catecholamine neurons in the locus coeruleus in human brains of normal young and older adults and in depression. J Comp Neurol 1989a; 287: 357-72.
6. Chan-Palay V, Asan E. Alterations in catecholamine neurons of the locus coeruleus in senile dementia of the Alzheimer type and in Parkinson's disease with and without dementia and depression. J Comp Neurol 1989b; 287: 373-92.
7. Cowell PE, Turetsky BI, Gur RC, Grossman RI, Shtasel DL, Gur RE. Sex differences in aging of the human frontal and temporal lobes. J Neurosci 1994; 14: 4748-55.
8. Curtsinger JW, Fukui HH, Townsend DR, Vaupel JW. Demography of genotypes: failure of the limited life-span paradigm in Drosophila melanogaster. Science 1992; 258: 461-3.
9. De Keyser J, Ebinger G, Vauquelin G. Age-related changes in the human nigrostriatal dopaminergic system. Ann Neurol 1990; 27: 157-61.
10. Doraiswamy PM, Na C, Husain MM, Figiel GS, McDonald WM, Ellinwood EH Jr, et al. Morphometric changes of the human midbrain with normal aging: MR and stereologic findings. AJNR Am J Neuroradiol 1992; 13: 383-6.
11. Fearnley JM, Lees AJ. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 1991; 114: 2283-301.
12. German DC, Dubach M, Askari S, Speciale SG, Bowden DM. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian syndrome in Macaca fascicularis: which midbrain dopaminergic neurons are lost? Neuroscience 1988; 24: 161-74.
13. Gibb WR, Lees AJ. Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease. J Neurol Neurosurg Psychiatry 1991; 54: 388-96.
14. Graybiel AM, Ragsdale CW Jr. Histochemically distinct compartments in the striatum of human, monkeys, and cat demonstrated by acetylthiocholinesterase staining. Proc Natl Acad Sci USA 1978; 75: 5723-6.
15. Hassler R. Zur Pathologie der Paralysis agitans und des postenzephalitischen Parkinsonismus. J Psychol Neurol 1938; 48: 387-476.
16. Hirai S. Histochemical study on the regressive degeneration of the senile brain, with special reference to the aging of the substantia nigra. Adv Neurol Sci (Tokyo) 1968; 12: 848-9.
17. Hirsch E, Graybiel AM, Agid YA. Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature 1988; 334: 345-8.
18. Hornykiewicz O. Dopamine (3-hydroxytyramine) and brain function. [Review]. Pharmacol Rev 1966; 18: 925-64.
19. Koller W, O'Hara R, Weiner W, Lang A, Nutt J, Agid Y, et al. Relationship of aging to Parkinson's disease. Adv Neurol 1987; 45: 317-21.
20. Mann DM, Yates PO. Possible role of neuromelanin in the pathogenesis of Parkinson's disease. Mech Ageing Dev 1983; 21: 193-203.
21. Martin WR, Palmer MR, Patlak CS, Calne DB. Nigrostriatal function in humans studied with positron emission tomography. Ann Neurol 1989; 26: 535-42.
22. McGeer PL, McGeer EG, Suzuki JS. Aging and extrapyramidal function. Arch Neurol 1977; 34: 33-5.
23. Mestre N, Bons N. Age-related cytological changes and neuronal loss in basal forebrain cholinergic neurons in Microcebus murinus (Lemurian, primate). Neurodegeneration 1993; 2: 25-32.
24. Morris JC, Drazner M, Fulling K, Grant EA, Goldring J. Clinical and pathological aspects of parkinsonism in Alzheimer's disease: a role for extranigral factors? Arch Neurol 1989; 46: 651-7.
25. Muthane U, Yasha TC, Shankar SK. Low numbers and no loss of melanized nigral neurons with increasing age in normal human brains from India. Ann Neurol 1998; 43: 283-7.
26. Newman RP, LeWitt PA, Jaffe M, Calne DB, Larsen TA. Motor function in the normal aging population: treatment with levodopa. Neurology 1985; 35: 571-3.
27. Price DL, Martin LJ, Sisodia SS, Wagster MV, Koo VE, Walker LC, et al. Aged non-human primates: an animal model of age-associated neurodegenerative disease. [Review]. Brain Pathol 1991; 1: 287-96.
28. 2 receptors. Brain Res 1990; 508: 349-52.
29. Sawle GV, Colebatch JG, Shah A, Brooks DJ, Marsden CD, Frackowiak RS. Striatal function in normal aging: implications for Parkinson's disease. Ann Neurol 1990; 28: 799-804.
30. Scherman D, Desnos C, Darchen F, Pollak P, Javoy-Agid F, Agid Y. Striatal dopamine deficiency in Parkinson's disease: role of aging. Ann Neurol 1989; 26: 551-7.
31. Smith PEM, Irving D, Perry RH. Density, distribution and prevalence of Lewy bodies in the elderly. Neurosci Res Commun 1991; 8: 127-35.
32. Thiessen B, Rajput AH, Desai H. Age, environments, and the number of substantia nigra neurons. Adv Neurol 1990; 53: 201-6.
33. Vacca LL. Double bridge techniques of immunohistochemistry. In: Bullock G, Petrusz P, editors. Techniques in immunohistochemistry. London: Academic Press; 1982. p. 155-82.
34. Vijayashankar N, Brody H. A quantitative study of the pigmented neurons in the nuclei locus coeruleus and subcoeruleus in man as related to aging. J Neuropathol Exp Neurol 1979; 38: 490-7.