Presynaptic recording of quanta from midbrain dopamine neurons and modulation of the quantal size

Journal of Neuroscience

Volumn 18, Issue 11, 1998, Pages 4106-4118

  Pothos, Emmanuel N ^b   Davila, Viviana ^b   Sulzer, David ^a  

^a Columbia University ^*  (United States)

^b NONE

Author keywords

Amperometry; Dopamine; Electrochemistry; Exocytosis; GDNF; L DOPA; Midbrain; Quantal analysis; Quantal release; Recycling; Synaptic vesicles; VMAT; Latrotoxin

Indexed keywords

ALPHA LATROTOXIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; LEVODOPA;

AMPEROMETRY; ANIMAL CELL; ARTICLE; CATECHOLAMINE NERVE CELL; DOPAMINERGIC NERVE CELL; EXTRACELLULAR CALCIUM; INTRACELLULAR RECORDING; LONG TERM POTENTIATION; NEUROTRANSMITTER RELEASE; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; SYNAPSE VESICLE;

EID: 0032100808     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-11-04106.1998     Document Type: Article

References (51)

1. Almers W, Tse FW (1990) Transmitter release from synapses; does a preassembled fusion pore initiate exocytosis? Neuron 4:813-818.
2. Beck KD, Irwin I, Valverde J, Brennan TJ, Langston JW, Hefti F (1996) GDNF induces a dystonia-like state in neonatal rats and stimulates dopamine and serotonin synthesis. Neuron 16:665-673.
3. Bekkers JM, Richerson GB, Stevens CF (1990) Origin of variability in quantal size in cultured hippocampal neurons and hippocampal slices. Proc Natl Acad Sci USA 87:5359-5362.
4. Bruns D, Jahn R (1995) Real-time measurement of transmitter release from single synaptic vesicles. Nature 377:62-65.
5. Burke R, Antonelli M, Sulzer D (1998) Glial-derived neurotrophic factor prevents apoptosis of substantia nigra neurons during their penou of natural cell death. J Neurochem, in press.
6. Chen G, Gavin PF, Luo G, Ewing AG (1995) Observation and quantitation of exocytosis from the cell body of a fully developed neuron in Planorbis corneus. J Neurosci 15:7747-7755.
7. Chow RH, von Ruden L (1995) Electrochemical detection of secretion from single cells. In: Single-channel recording (Sakmann B, Neher E, eds), pp 245-276, New York: Plenum.
8. Ciolkowski EL, Maness KM, Cahill PS, Wightman RM, Evans DH, Fosset B, Amatore C (1994) Disproportionation during electrooxidation of catecholamines at carbon-fiber microelectrodes. Anal Chem 66:3611-3617.
9. Durbec P, Marcos-Gutierrez CV, Kilkenny C, Grigoriou M, Wartiowaara K, Suvanto P, Smith D, Ponder B, Costantini F, Saarma M, Sanola H, Pachnis V (1996) GDNF signalling through the Ret receptor tyrosine kinase. Nature 381:789-793.
10. Edwards FA (1995) Anatomy and electrophysiology of fast central synapses lead to a structural model for long-term potentiatron. Physiol Rev 75:759-787.
11. Finnegan JM, Pihel K, Cahill PS, Haung L, Zerby SE, Ewing AG, Kennedy RT, Wightman RM (1996) Vesicular quantal size measured by amperometry at chromaffin, mast, pheochromocytoma, and pancreatic beta cells. J Neurochem 66:1914-1923.
12. Fon T, Pothos EN, Sun BC, Killeen N, Sulzer D, Edwards RH (1997) Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. Neuron 19:1271-1283.
13. Forti L, Bossi M, Bergamaschi A, Villa A, Malgaroli A (1997) Loosepatch recordings of single quanta at individual hippocampal synapses. Nature 388:874-878.
14. Frerking M, Borges S, Wilson M (1995) Variation in GABA mini amplitude is the consequence of variation in transmitter concentration. Neuron 15:885-895.
15. Garris PA, Ciolkowski EL, Pastore P, Wightman RM (1994) Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain. J Neurosci 14:6084-6093.
16. Hebert MA, Van Hörne CG, Hoffer BJ, Gerhardt GA (1996) Functional effects of GDNF in normal rat striatum: presynaptic studies using in vivo electrochemistry and microdialysis. J Pharmacol Exp Ther 279:1181-1190.
17. Jing S, Wen D, Yu Y, Holst PL, Luo Y, Fang M, Tamir R, Antonio L, Hu Z, Cupples R, Louis JC, Hu S, Altrock BW, Fox GM (1996) GDNF-induced activation of the Ret protein tyrosine kinase is mediated by GDNFR-α, a novel receptor for GDNF. Cell 85:1113-1124.
18. Kang H, Schuman EM (1995) Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science 267:1658-1662.
19. Kullmann DM, Eredmil G, Asztely F (1996) LTP of AMPA and NMDA receptor-mediated signals: evidence for presynaptic expression and extrasynaptic glutamate spill-over. Neuron 17:461-474.
20. Kumer SC, Vrana KE (1996) Intricate regulation of tyrosine hydroxylase activity and gene expression. J Neurochem 67:443-462.
21. Leszczyszyn DJ, Jankowski JA, Viveros OH, Diliberto Jr EJ, Near JA, Wightman RM (1991) Secretion of catecholamines from individual adrenal medullary chromaffin cells. J Neurochem 56:1855-1863.
22. Lin L-FH, Doherty DH, Lile JD, Bektesh S, Collins F (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260:1130-1132.
23. Liu G, Tsien RW (1995) Properties of synaptic transmission at single hippocampal synaptic boutons. Nature 375:404-408.
24. Marshall DL, Redfern PH, Wonnacott S (1997) Presynaptic nicotinic modulation of dopamine release in the three ascending pathways studied by in vivo microdialysis: comparison of naive and chronic nicotinetreated rats. J Neurochem 68:1511-1519.
25. Mena MA, Davila V, Sulzer D (1997) Neurotrophic effects of L-DOPA in postnatal midbrain dopamine/cortical astrocyte co-culture. J Neurochem 69:1398-1408.
26. Mennerick S, Matthews G (1996) Ultrafast exocytosis elicited by calcium current in synaptic terminals of retinal bipolar neurons. Neuron 17:1241-1249.
27. Nirenberg MJ, Chan J, Liu Y, Edwards RH, Pickel VM (1997) Vesicular monoamine transporter-2: immunogold localization in striatal axons and terminals. Synapse 26:194-198.
28. Parsons TD, Lenzi D, Almers W, Roberts WM (1994) Calciumtriggered exocytosis and endocytosis in an isolated presynaptic cell: capacitance measurements in saccular hair cells. Neuron 13:875-883.
29. Petrenko AG (1993) α-Latrotoxin receptor. Implications in nerve terminal function. FEBS Lett 325:81-85.
30. Pothos E, Desmund M, Sulzer D (1996) L-3,4-Dihydroxyphenylalanine increases the quantal size of exocytic dopamine release in vitro. J Neurochem 66:629-636.
31. Przedborski S, Khan U, Kostic V, Carlson E, Epstein CJ, Sulzer D (1996) Increased Superoxide dismutase activity improves survival of cultured postnatal midbrain neurons. J Neurochem 67:1383-1392.
32. Rahamimoff R, Fernandez JM (1997) Pre- and postfusion regulation of transmitter release. Neuron 18:17-27.
33. Rayport S, Sulzer D, Shi W-X, Sawasdikosol S, Monaco J, Batson D, Rajendran G (1992) Identified postnatal mesolimbic dopamine neurons in cell culture: morphology and electrophysiology. J Neurosci 32:4264-4280.
34. Rebec GV, Pierce RC (1994) A vitamin as neuromodulator: ascorbate release into the extracellular fluid of the brain regulates dopaminergic and glutamatergic transmission. Prog Neurobiol 43:537-565.
35. Rieke F, Schwartz EA (1994) A cGMP-gated current can control exocytosis at cone synapses. Neuron 13:863-873.
36. Ryan TA, Reuter H, Smith SJ (1997) Optical detection of a quantal presynaptic membrane turnover. Nature 388:478-482.
37. Schroeder TJ, Jankowski JA, Kawagoe KT, Wrghtman RM, Lefrou C, Amatore C (1992) Analysis of diffusional broadening of vesicular packets of catecholamines released from biological cells during exocy- tosis. Anal Chem 64:3077-3083.
38. Song HJ, Ming GL, Fon E, Bellocchio E, Edwards RH, Poo MM (1997) Expression of a putative vesicular acetylcholine transporter facilitates quantal transmitter packaging. Neuron 18:815-826.
39. Steyer JA, Horstmann H, Almers W (1997) Transport, docking, and exocytosis of single secretory granules in live chromaffin cells. Nature 474-478.
40. Stoop R, Poo MM (1996a) Synaptic modulation by neurotrophic factors. Prog Brain Res 109:359-364.
41. Stoop R, Poo MM (1996b) Synaptic modulation by neurotrophic factors: differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor. J Neurosci 16:3256-3264.
42. Sulzer D, Rayport S (1990) Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action. Neuron 5:797-808.
43. Sulzer D, Chen TK, Lau YY, Kristensen H, Rayport S, Ewing A (1995) Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport. J Neurosci 15:4102-4108.
44. Sulzer D, St. Remy C, Rayport S (1996) Reserpine inhibits amphetamine action in ventral midbrain culture. Mol Pharmacol 49:342-348.
45. Tang CM, Margulis M, Shi QY, Fielding A (1994) Saturation of postsynaptic glutamate receptors after quantal release of transmitter. Neuron 13:1385-1393.
46. Thoenen H (1995) Neurotrophins and neuronal plasticity. Science 270:593-598.
47. Tong G, Jahr CE (1994) Multivesicular release from excitatory synapses of cultured hippocampal neurons. Neuron 12:51-59.
48. Van der Kloot W (1991) The regulation of quantal size. Prog Neurobiol 36:93-130.
49. Van der Kloot W, Molgo J (1995) The relationship between quantal content and delayed quantal release. NeuroReport 6:1807-1810.
50. Wang T, Xie K, Lu B (1995) Neurotrophins promote maturation of developing neuromuscular synapses. J Neurosci 15:4796-4805.
51. Zhou Z, Misler S (1995) Amperometric detection of stimulus-induced quantal release of catecholamines from cultured superior cervical ganglion neurons. Proc Natl Acad Sci USA 92:6938-6942.