Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 5, 1997, Pages 2019-2024

  Steiner, Joseph P ^a   Hamilton, Gregory S ^a   Ross, Douglas T ^a   Valentine, Heather L ^a   Guo, Hongzhi ^a   Connolly, Maureen A ^a   Liang, Shi ^a   Ramsey, Cynthia ^a   Li, Jia He J ^a   Huang, Wei ^a   Howorth, Pamela ^a   Soni, Rajat ^a   Fuller, Michael ^a   Sauer, Hans ^a   Nowotnik, Alison C ^a   Suzdak, Peter D ^a  

^a GUILFORD PHARMACEUTICALS INC   (United States)

Author keywords

calcineurin; cyclophilin; cyclosporin A; dopamine; FK506

Indexed keywords

1 (3,3 DIMETHYL 1,2 DIOXOPENTYL) 2 PYRROLIDINECARBOXYLIC ACID 3 (3 PYRIDYL)PROPYL ESTER; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CALCINEURIN; CYCLOSPORIN; CYCLOSPORIN A; DOPAMINE; IMMUNOPHILIN; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; OXIDOPAMINE; TACROLIMUS; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOPAMINERGIC NERVE CELL; DRUG PROTEIN BINDING; EMBRYO; MALE; NERVE FIBER GROWTH; NERVE INJURY; NEUROTROPISM; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SEROTONINERGIC NERVE CELL; SOMATOSENSORY CORTEX; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALIA;

EID: 12644257556     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.5.2019     Document Type: Article

References (29)

1. Schreiber, S. L. (1991) Science 253, 283-287.
2. Liu, J., Farmer, J. D., Lane, W. S., Friedman, J., Weissman, I. & Schreiber, S. L. (1991) Cell 66, 807-815.
3. Bierer, B. E., Somers, P. K., Wandless, T. J., Burakoff, S. J. & Schreiber, S. L. (1990) Science 250, 556-559.
4. Siekierka, J. J., Hung, S. H. Y., Poe, M., Lin, C. S. & Sigal, N. H. (1989) Nature (London) 341, 755-757.
5. Harding, M. W., Galat, A., Uehling, D. E. & Schreiber, S. L. (1989) Nature (London) 341, 758-760.
6. Fischer, G., Wittmann-Liebold, B., Lang, K., Kiefhaber, T. & Schmid, F. X. (1989) Nature (London) 340, 351-352.
7. Dumont, F. J., Staruch, M. J., Koprak, S. L., Siekierka, J. J., Lin, C. S., Harrison, R., Sewell, T., Kindt, V. M., Beattie, T. R., Wyvratt, M. & Sigal, N. (1992) J. Exp. Med. 176, 751-760.
8. Steiner, J. P., Dawson, T. M., Fotuhi, M., Glatt, C. E., Snowman, A. M., Cohen, N. & Snyder, S. H. (1992) Nature (London) 358, 584-587.
9. Lyons, W. E., Steiner, J. P., Snyder, S. H. & Dawson, T. M. (1995) J. Neurosci. 15, 2985-2994.
10. Lyons, W. E., George, E. B., Dawson, T. M., Steiner, J. P. & Snyder, S. H. (1994) Proc. Natl. Acad. Sci. USA 91, 3191-3195.
11. Gold, B. G., Storm-Dickerson, T. & Austin, D. R. (1994) Restorative Neurol. Neurosci. 6, 287-296.
12. Gold, B. G., Katoh, K. & Storm-Dickerson, T. (1995) J. Neurosci. 15, 7509-7516.
13. Kofron, J. L., Kuzmic, P., Kishore, V., Colon-Bonilla, E. & Rich, D. H. (1991) Biochemistry 30, 6127-6134.
14. Mamounas, L. A., Blue, M. E., Siuciak, J. A. & Altar, C. A. (1995) J. Neurosci. 15, 7929-7939.
15. Gerlach, M., Riederer, P., Przuntek, H. & Youdin, M. B. H. (1991) Eur. J. Pharmacol. 208, 273-286.
16. Sachs, C. & Jonsson, G. (1975) Biochem. Pharmacol. 24, 1-8.
17. Jonsson, G. (1980) Annu. Rev. Neurosci. 3, 169-187.
18. Ungerstedt, U. & Arburthnott, G. W. (1970) Brain Res. 24, 485-493.
19. Schneider, J. S. & Yuwiler, A. (1989) Exp. Neurol. 105, 177-183.
20. Tatton, W. G. & Greenwood, C. E. (1991) J. Neurosci. Res. 30, 666-672.
21. Muthane, U., Ramsay, K. A., Jiang, H., Jackson-Lewis, V., Donaldson, D., Fernando, S., Ferreira, M. & Przedborski, S. (1994) Exp. Neurol. 126, 195-204.
22. Hadjiconstantinou, M., Fitkin, J. G., Dalia, A. & Neff, N. H. (1991) J. Neurochem. 57, 479-482.
23. Schneider, J. S. & DiStefano, L. (1995) Brain Res. 674, 260-264.
24. Garcia, E., Rios, C. & Sotelo, J. (1992) Neurochem. Res. 17, 979-982.
25. Tomac, A., Lindquist, E., Lin, L.-F. H., Ogren, S. O., Young, D., Hoffer, J. & Olson, L. (1995) Nature (London) 373, 335.
26. Hadjiconstantinou, M. & Neff, N. H. (1990) Exp. J. Pharmacol. 181, 137-139.
27. Schneider, J. S. & DiStefano, L. (1994) Neurology 44, 748-750.
28. Gash, D. M., Zhang, Z., Ovadia, A., Cass, W. A., Yi, A., Simmerman, L., Russell, D., Martin, D., Lapchak, P. A., Collins, F., Hoffer, B. J. & Gerhardt, G. A. (1996) Nature (London) 380, 252-255.
29. Woolf, C. J., Ma, Q. P., Allchorne, A. & Poole, S. (1996) J. Neurosci. 16, 2716-2723.