Failure of GPI compounds to display neurotrophic activity in vitro and in vivo

European Journal of Pharmacology

Volumn 415, Issue 2-3, 2001, Pages 173-180

  Bocquet, Arnaud ^a   Lorent, Geneviève ^a   Fuks, Bruno ^a   Grimée, Renée ^a   Talaga, Patrice ^a   Daliers, Jean ^a   Klitgaard, Henrik ^a  

^a UCB PHARMA   (Belgium)

Author keywords

(Mouse); Dorsal root ganglia; Immunophilin; MPTP (1 methyl 4 phenyl 1, 2, 3, 6 tetrahydropyridine); Neuroprotection; Rotamase

Indexed keywords

1 (3,3 DIMETHYL 1,2 DIOXOPENTYL) 2 PYRROLIDINECARBOTHIOIC ACID (3 PHENYLPROPYL)ESTER; 1 (3,3 DIMETHYL 1,2 DIOXOPENTYL) 2 PYRROLIDINECARBOXYLIC ACID 3 (1 OXY 3 PYRIDYL)PROPYL ESTER; 1 (3,3 DIMETHYL 1,2 DIOXOPENTYL) 2 PYRROLIDINECARBOXYLIC ACID 3 (3 PYRIDYL)PROPYL ESTER; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CYCLOPHILIN; DOPAMINE; FK 506 BINDING PROTEIN; IMMUNOPHILIN; LIGAND; NERVE GROWTH FACTOR; RAPAMYCIN; TACROLIMUS; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE BRAIN LEVEL; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; NERVE CELL; NERVE FIBER GROWTH; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; SPINAL GANGLION;

ANIMALS; DOPAMINE; GANGLIA, SPINAL; IMMUNOSUPPRESSIVE AGENTS; LIGANDS; MALE; MICE; MICE, INBRED C57BL; MPTP POISONING; NEUROPROTECTIVE AGENTS; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; SIROLIMUS; TACROLIMUS BINDING PROTEINS;

EID: 0035896266     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)00850-0     Document Type: Article

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