-
2
-
-
0028943243
-
Notch Signaling
-
Artavanis-Tsakonas S., et al. Notch Signaling. Science 268 (1995) 225-232
-
(1995)
Science
, vol.268
, pp. 225-232
-
-
Artavanis-Tsakonas, S.1
-
3
-
-
0031451172
-
The LIN-12/Notch signaling pathway and its regulation
-
Kimble J., and Simpson P. The LIN-12/Notch signaling pathway and its regulation. Annu. Rev. Cell Dev. Biol. 13 (1997) 333-361
-
(1997)
Annu. Rev. Cell Dev. Biol.
, vol.13
, pp. 333-361
-
-
Kimble, J.1
Simpson, P.2
-
4
-
-
33947241465
-
SnapShot: notch signaling pathway
-
Ilagan M.X., and Kopan R. SnapShot: notch signaling pathway. Cell 128 (2007) 1246
-
(2007)
Cell
, vol.128
, pp. 1246
-
-
Ilagan, M.X.1
Kopan, R.2
-
5
-
-
33747623018
-
Notch signaling: a simple pathway becomes complex
-
Bray S.J. Notch signaling: a simple pathway becomes complex. Nat. Rev. Mol. Cell Biol. 7 (2006) 678-689
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 678-689
-
-
Bray, S.J.1
-
6
-
-
0028216808
-
Notch1 is essential for postimplantation development in mice
-
Swiatek P.J., et al. Notch1 is essential for postimplantation development in mice. Genes Dev. 8 (1994) 707-719
-
(1994)
Genes Dev.
, vol.8
, pp. 707-719
-
-
Swiatek, P.J.1
-
7
-
-
0034212710
-
Notch signaling is essential for vascular morphogenesis in mice
-
Krebs L.T., et al. Notch signaling is essential for vascular morphogenesis in mice. Genes Dev. 14 (2000) 1343-1352
-
(2000)
Genes Dev.
, vol.14
, pp. 1343-1352
-
-
Krebs, L.T.1
-
8
-
-
0035097937
-
Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation
-
McCright B., et al. Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development 128 (2001) 491-502
-
(2001)
Development
, vol.128
, pp. 491-502
-
-
McCright, B.1
-
9
-
-
8644219667
-
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells
-
Domenga V., et al. Notch3 is required for arterial identity and maturation of vascular smooth muscle cells. Genes Dev. 18 (2004) 2730-2735
-
(2004)
Genes Dev.
, vol.18
, pp. 2730-2735
-
-
Domenga, V.1
-
10
-
-
0345689442
-
Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation
-
Krebs L.T., et al. Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation. Genesis 37 (2003) 139-143
-
(2003)
Genesis
, vol.37
, pp. 139-143
-
-
Krebs, L.T.1
-
11
-
-
33947259525
-
Glucocorticoid and growth factor synergism requirement for Notch4 chromatin domain activation
-
Wu J., and Bresnick E.H. Glucocorticoid and growth factor synergism requirement for Notch4 chromatin domain activation. Mol. Cell. Biol. 27 (2007) 2411-2422
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 2411-2422
-
-
Wu, J.1
Bresnick, E.H.2
-
12
-
-
33745147915
-
SOX2 is a dose-dependent regulator of retinal neural progenitor competence
-
Taranova O.V., et al. SOX2 is a dose-dependent regulator of retinal neural progenitor competence. Genes Dev. 20 (2006) 1187-1202
-
(2006)
Genes Dev.
, vol.20
, pp. 1187-1202
-
-
Taranova, O.V.1
-
13
-
-
0037227099
-
Multipotent cell lineages in early mouse development depend on Sox2 function
-
Avilion A.A., et al. Multipotent cell lineages in early mouse development depend on Sox2 function. Genes Dev. 17 (2003) 126-140
-
(2003)
Genes Dev.
, vol.17
, pp. 126-140
-
-
Avilion, A.A.1
-
14
-
-
34249880066
-
Generation of germline-competent induced pluripotent stem cells
-
Okita K., et al. Generation of germline-competent induced pluripotent stem cells. Nature 6 (2007) 313-317
-
(2007)
Nature
, vol.6
, pp. 313-317
-
-
Okita, K.1
-
15
-
-
34249908901
-
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
-
Wernig M., et al. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 6 (2007) 318-324
-
(2007)
Nature
, vol.6
, pp. 318-324
-
-
Wernig, M.1
-
16
-
-
0024804191
-
A protein binding to the Jk recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif
-
Matsunami N., et al. A protein binding to the Jk recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif. Nature 342 (1989) 934-937
-
(1989)
Nature
, vol.342
, pp. 934-937
-
-
Matsunami, N.1
-
17
-
-
0033868818
-
A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE
-
Brou C., et al. A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE. Mol. Cell 5 (2000) 207-216
-
(2000)
Mol. Cell
, vol.5
, pp. 207-216
-
-
Brou, C.1
-
18
-
-
0033535504
-
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
-
De Strooper B., et al. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature 398 (1999) 518-522
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
-
19
-
-
0030063909
-
Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2
-
Hsieh J.J., et al. Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol. Cell. Biol. 16 (1996) 952-959
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 952-959
-
-
Hsieh, J.J.1
-
20
-
-
34248139757
-
The Hes gene family: repressors and oscillators that orchestrate embryogenesis
-
Kageyama R., et al. The Hes gene family: repressors and oscillators that orchestrate embryogenesis. Development 134 (2007) 1243-1251
-
(2007)
Development
, vol.134
, pp. 1243-1251
-
-
Kageyama, R.1
-
21
-
-
0032508711
-
Identity of the beta-globin locus control region binding protein HS2NF5 as the mammalian homolog of the notch-regulated transcription factor suppressor of hairless
-
Lam L.T., and Bresnick E.H. Identity of the beta-globin locus control region binding protein HS2NF5 as the mammalian homolog of the notch-regulated transcription factor suppressor of hairless. J. Biol. Chem. 273 (1998) 24223-24231
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 24223-24231
-
-
Lam, L.T.1
Bresnick, E.H.2
-
22
-
-
17644438177
-
The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients
-
Joutel A., et al. The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients. J. Clin. Invest. 105 (2000) 597-605
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 597-605
-
-
Joutel, A.1
-
23
-
-
0028289647
-
The novel Notch homolog mouse Notch3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium
-
Lardelli M., et al. The novel Notch homolog mouse Notch3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium. Mech. Dev. 46 (1994) 123-136
-
(1994)
Mech. Dev.
, vol.46
, pp. 123-136
-
-
Lardelli, M.1
-
24
-
-
0030054646
-
Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene
-
Uyttendaele H., et al. Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. Development 122 (1996) 2251-2259
-
(1996)
Development
, vol.122
, pp. 2251-2259
-
-
Uyttendaele, H.1
-
25
-
-
22844440114
-
Notch signaling in the mammalian central nervous system: insights from mouse mutants
-
Yoon K., and Gaiano N. Notch signaling in the mammalian central nervous system: insights from mouse mutants. Nat. Neurosci. 8 (2005) 709-715
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 709-715
-
-
Yoon, K.1
Gaiano, N.2
-
26
-
-
24344443668
-
The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis
-
Luo D., et al. The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis. Semin. Cell Dev. Biol. 16 (2005) 612-622
-
(2005)
Semin. Cell Dev. Biol.
, vol.16
, pp. 612-622
-
-
Luo, D.1
-
27
-
-
34247224342
-
Regulation of lymphocyte development by Notch signaling
-
Tanigaki K., and Honjo T. Regulation of lymphocyte development by Notch signaling. Nat. Immunol. 8 (2007) 451-456
-
(2007)
Nat. Immunol.
, vol.8
, pp. 451-456
-
-
Tanigaki, K.1
Honjo, T.2
-
28
-
-
34548164780
-
Notch signaling in vascular development and physiology
-
Gridley T. Notch signaling in vascular development and physiology. Development 134 (2007) 2709-2718
-
(2007)
Development
, vol.134
, pp. 2709-2718
-
-
Gridley, T.1
-
29
-
-
33745214464
-
Ectopic pancreas formation in Hes1-knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas
-
Fukuda A., et al. Ectopic pancreas formation in Hes1-knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas. J. Clin. Invest. 116 (2006) 1484-1493
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1484-1493
-
-
Fukuda, A.1
-
30
-
-
0442309823
-
A dual role for Iκκ α in tooth development
-
Ohazama A., et al. A dual role for Iκκ α in tooth development. Dev. Cell 6 (2004) 219-227
-
(2004)
Dev. Cell
, vol.6
, pp. 219-227
-
-
Ohazama, A.1
-
31
-
-
3342891403
-
Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression
-
Lefort K., and Dotto G.P. Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression. Semin. Cancer Biol. 14 (2004) 374-386
-
(2004)
Semin. Cancer Biol.
, vol.14
, pp. 374-386
-
-
Lefort, K.1
Dotto, G.P.2
-
32
-
-
13244298117
-
Notch and epithelial-mesenchyme transition in development and tumor progression: another turn of the screw
-
Grego-Bessa J., et al. Notch and epithelial-mesenchyme transition in development and tumor progression: another turn of the screw. Cell Cycle 3 (2004) 718-721
-
(2004)
Cell Cycle
, vol.3
, pp. 718-721
-
-
Grego-Bessa, J.1
-
33
-
-
0028989016
-
Notch1 is required for the coordinate segmentation of somites
-
Conlon R.A., et al. Notch1 is required for the coordinate segmentation of somites. Development 121 (1995) 1533-1545
-
(1995)
Development
, vol.121
, pp. 1533-1545
-
-
Conlon, R.A.1
-
34
-
-
0032868937
-
Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality
-
Hamada Y., et al. Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Development 126 (1999) 3415-3424
-
(1999)
Development
, vol.126
, pp. 3415-3424
-
-
Hamada, Y.1
-
35
-
-
33947312487
-
Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron
-
Cheng H.T., et al. Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development 134 (2007) 801-811
-
(2007)
Development
, vol.134
, pp. 801-811
-
-
Cheng, H.T.1
-
36
-
-
0032820657
-
The notch 3 intracellular domain represses notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters
-
Beatus P., et al. The notch 3 intracellular domain represses notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters. Development 126 (1999) 3925-3935
-
(1999)
Development
, vol.126
, pp. 3925-3935
-
-
Beatus, P.1
-
37
-
-
23444450200
-
Functional conservation of Notch1 and Notch2 intracellular domains
-
Kraman M., and McCright B. Functional conservation of Notch1 and Notch2 intracellular domains. FASEB J. 19 (2005) 1311-1313
-
(2005)
FASEB J.
, vol.19
, pp. 1311-1313
-
-
Kraman, M.1
McCright, B.2
-
38
-
-
0035826844
-
Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium
-
Uyttendaele H., et al. Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 5643-5648
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 5643-5648
-
-
Uyttendaele, H.1
-
39
-
-
22244470426
-
Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice
-
Carlson T.R., et al. Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 9884-9889
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 9884-9889
-
-
Carlson, T.R.1
-
40
-
-
0034778258
-
Notch signaling is required for arterial-venous differentiation during embryonic vascular development
-
Lawson N.D., et al. Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development 128 (2001) 3675-3683
-
(2001)
Development
, vol.128
, pp. 3675-3683
-
-
Lawson, N.D.1
-
41
-
-
0035829517
-
Gridlock signalling pathway fashions the first embryonic artery
-
Zhong T.P., et al. Gridlock signalling pathway fashions the first embryonic artery. Nature 414 (2001) 216-220
-
(2001)
Nature
, vol.414
, pp. 216-220
-
-
Zhong, T.P.1
-
42
-
-
0034817456
-
Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels
-
Villa N., et al. Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels. Mech. Dev. 108 (2001) 161-164
-
(2001)
Mech. Dev.
, vol.108
, pp. 161-164
-
-
Villa, N.1
-
43
-
-
33644782668
-
Recent insights into the role of Notch signaling in tumorigenesis
-
Leong K.G., and Karsan A. Recent insights into the role of Notch signaling in tumorigenesis. Blood 107 (2006) 2223-2233
-
(2006)
Blood
, vol.107
, pp. 2223-2233
-
-
Leong, K.G.1
Karsan, A.2
-
44
-
-
0037370310
-
Notch1 functions as a tumor suppressor in mouse skin
-
Nicolas M., et al. Notch1 functions as a tumor suppressor in mouse skin. Nat. Genet. 33 (2003) 416-421
-
(2003)
Nat. Genet.
, vol.33
, pp. 416-421
-
-
Nicolas, M.1
-
45
-
-
0025856717
-
TAN-1, the homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
-
Ellisen L.W., et al. TAN-1, the homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66 (1991) 649-661
-
(1991)
Cell
, vol.66
, pp. 649-661
-
-
Ellisen, L.W.1
-
46
-
-
0033796150
-
Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1
-
Aster J.C., et al. Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1. Mol. Cell. Biol. 20 (2000) 7505-7515
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7505-7515
-
-
Aster, J.C.1
-
47
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
Weng A.P., et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306 (2004) 269-271
-
(2004)
Science
, vol.306
, pp. 269-271
-
-
Weng, A.P.1
-
48
-
-
0023226698
-
A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17
-
Gallahan D., et al. A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17. J. Virol. 61 (1987) 218-220
-
(1987)
J. Virol.
, vol.61
, pp. 218-220
-
-
Gallahan, D.1
-
49
-
-
0026517312
-
Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands
-
Jhappan C., et al. Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands. Genes Dev. 6 (1992) 345-355
-
(1992)
Genes Dev.
, vol.6
, pp. 345-355
-
-
Jhappan, C.1
-
50
-
-
0034642524
-
Identification of a novel NOTCH-4/INT-3 RNA species encoding an activated gene product in certain human tumor cell lines
-
Imatani A., and Callahan R. Identification of a novel NOTCH-4/INT-3 RNA species encoding an activated gene product in certain human tumor cell lines. Oncogene 19 (2000) 223-231
-
(2000)
Oncogene
, vol.19
, pp. 223-231
-
-
Imatani, A.1
Callahan, R.2
-
51
-
-
0036734148
-
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells
-
Weijzen S., et al. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat. Med. 8 (2002) 979-986
-
(2002)
Nat. Med.
, vol.8
, pp. 979-986
-
-
Weijzen, S.1
-
52
-
-
0029078323
-
Alterations in Notch signaling in neoplastic lesions of the human cervix
-
Zagouras P., et al. Alterations in Notch signaling in neoplastic lesions of the human cervix. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 6414-6418
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 6414-6418
-
-
Zagouras, P.1
-
53
-
-
33644623134
-
CADASIL: a critical look at a Notch disease
-
Louvi A., et al. CADASIL: a critical look at a Notch disease. Dev. Neurosci. 28 (2006) 5-12
-
(2006)
Dev. Neurosci.
, vol.28
, pp. 5-12
-
-
Louvi, A.1
-
54
-
-
0037221480
-
Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
-
Ruchoux M.M., et al. Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Am. J. Pathol. 162 (2003) 329-342
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 329-342
-
-
Ruchoux, M.M.1
-
55
-
-
0036070186
-
sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation
-
Lawson N.D., et al. sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev. Cell 3 (2002) 127-136
-
(2002)
Dev. Cell
, vol.3
, pp. 127-136
-
-
Lawson, N.D.1
-
56
-
-
0037216703
-
Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis
-
Liu Z.J., et al. Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. Mol. Cell. Biol. 23 (2003) 14-25
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 14-25
-
-
Liu, Z.J.1
-
57
-
-
1842425617
-
Evidence that C promoter-binding factor 1 binding is required for Notch-1-mediated repression of activator protein-1
-
Chu J., and Bresnick E.H. Evidence that C promoter-binding factor 1 binding is required for Notch-1-mediated repression of activator protein-1. J. Biol. Chem. 279 (2004) 12337-12345
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 12337-12345
-
-
Chu, J.1
Bresnick, E.H.2
-
58
-
-
0037090983
-
Reciprocal regulatory interactions between the Notch and Ras signaling pathways in the Drosophila embryonic mesoderm
-
Carmena A., et al. Reciprocal regulatory interactions between the Notch and Ras signaling pathways in the Drosophila embryonic mesoderm. Dev. Biol. 244 (2002) 226-242
-
(2002)
Dev. Biol.
, vol.244
, pp. 226-242
-
-
Carmena, A.1
-
59
-
-
33745923516
-
Role of Sox2 in the development of the mouse neocortex
-
Bani-Yaghoub M., et al. Role of Sox2 in the development of the mouse neocortex. Dev. Biol. 295 (2006) 52-66
-
(2006)
Dev. Biol.
, vol.295
, pp. 52-66
-
-
Bani-Yaghoub, M.1
-
60
-
-
16844363879
-
Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation
-
Mansukhani A., et al. Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation. J. Cell Biol. 168 (2005) 1065-1076
-
(2005)
J. Cell Biol.
, vol.168
, pp. 1065-1076
-
-
Mansukhani, A.1
-
61
-
-
2542500471
-
FGF2 triggers iris-derived lens regeneration in newt eye
-
Hayashi T., et al. FGF2 triggers iris-derived lens regeneration in newt eye. Mech. Dev. 121 (2004) 519-526
-
(2004)
Mech. Dev.
, vol.121
, pp. 519-526
-
-
Hayashi, T.1
-
62
-
-
13444301186
-
Molecular determinants of NOTCH4 transcription in vascular endothelium
-
Wu J., et al. Molecular determinants of NOTCH4 transcription in vascular endothelium. Mol. Cell. Biol. 25 (2005) 1458-1474
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1458-1474
-
-
Wu, J.1
-
63
-
-
0001395691
-
Fringe is a glycosyltransferase that modifies Notch
-
Moloney D.J., et al. Fringe is a glycosyltransferase that modifies Notch. Nature 406 (2000) 369-375
-
(2000)
Nature
, vol.406
, pp. 369-375
-
-
Moloney, D.J.1
-
65
-
-
0037069661
-
Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans
-
Shaye D.D., and Greenwald I. Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans. Nature 420 (2002) 686-690
-
(2002)
Nature
, vol.420
, pp. 686-690
-
-
Shaye, D.D.1
Greenwald, I.2
-
66
-
-
0034680909
-
Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase
-
Qiu L., et al. Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase. J. Biol. Chem. 275 (2000) 35734-35737
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35734-35737
-
-
Qiu, L.1
-
67
-
-
32444437676
-
Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change
-
Gallagher E., et al. Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 1717-1722
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 1717-1722
-
-
Gallagher, E.1
-
68
-
-
0029047609
-
Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats
-
Matsuno K., et al. Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development 121 (1995) 2633-2644
-
(1995)
Development
, vol.121
, pp. 2633-2644
-
-
Matsuno, K.1
-
69
-
-
0033595679
-
Contact-dependent inhibition of cortical neurite growth mediated by notch signaling
-
Sestan N., et al. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science 286 (1999) 689-690
-
(1999)
Science
, vol.286
, pp. 689-690
-
-
Sestan, N.1
-
70
-
-
28544440935
-
Regulation of Notch signalling by non-visual β-arrestin
-
Mukherjee A., et al. Regulation of Notch signalling by non-visual β-arrestin. Nat. Cell Biol. 7 (2005) 1191-1201
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 1191-1201
-
-
Mukherjee, A.1
-
71
-
-
0035929669
-
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog
-
Oberg C., et al. The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog. J. Biol. Chem. 276 (2001) 35847-35853
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35847-35853
-
-
Oberg, C.1
-
72
-
-
0034791336
-
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation
-
Wu G., et al. SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation. Mol. Cell. Biol. 21 (2001) 7403-7415
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7403-7415
-
-
Wu, G.1
-
73
-
-
0035860804
-
Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor
-
Gupta-Rossi N., et al. Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor. J. Biol. Chem. 276 (2001) 34371-34378
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34371-34378
-
-
Gupta-Rossi, N.1
-
74
-
-
0036897569
-
Asymmetric segregation of Numb: a mechanism for neural specification from Drosophila to mammals
-
Cayouette M., and Raff M. Asymmetric segregation of Numb: a mechanism for neural specification from Drosophila to mammals. Nat. Neurosci. 5 (2002) 1265-1269
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 1265-1269
-
-
Cayouette, M.1
Raff, M.2
-
75
-
-
0036696444
-
The endocytic protein α-adaptin is required for numb-mediated asymmetric cell division in Drosophila
-
Berdnik D., et al. The endocytic protein α-adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev. Cell 3 (2002) 221-231
-
(2002)
Dev. Cell
, vol.3
, pp. 221-231
-
-
Berdnik, D.1
-
76
-
-
0037663379
-
Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain
-
McGill M.A., and McGlade C.J. Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain. J. Biol. Chem. 278 (2003) 23196-23203
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23196-23203
-
-
McGill, M.A.1
McGlade, C.J.2
-
77
-
-
0042442453
-
Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila
-
O'Connor-Giles K.M., and Skeath J.B. Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila. Dev. Cell 5 (2003) 231-243
-
(2003)
Dev. Cell
, vol.5
, pp. 231-243
-
-
O'Connor-Giles, K.M.1
Skeath, J.B.2
-
78
-
-
0036215712
-
Cortisol regulates the expression of Notch in osteoblasts
-
Pereira R.M., et al. Cortisol regulates the expression of Notch in osteoblasts. J. Cell. Biochem. 85 (2002) 252-258
-
(2002)
J. Cell. Biochem.
, vol.85
, pp. 252-258
-
-
Pereira, R.M.1
-
79
-
-
0037195730
-
Determinants of Notch-3 receptor expression and signaling in vascular smooth muscle cells: implications in cell-cycle regulation
-
Campos A.H., et al. Determinants of Notch-3 receptor expression and signaling in vascular smooth muscle cells: implications in cell-cycle regulation. Circ. Res. 91 (2002) 999-1006
-
(2002)
Circ. Res.
, vol.91
, pp. 999-1006
-
-
Campos, A.H.1
-
80
-
-
0345304893
-
Induction of Notch signaling by tumor necrosis factor in rheumatoid synovial fibroblasts
-
Ando K., et al. Induction of Notch signaling by tumor necrosis factor in rheumatoid synovial fibroblasts. Oncogene 22 (2003) 7796-7803
-
(2003)
Oncogene
, vol.22
, pp. 7796-7803
-
-
Ando, K.1
-
81
-
-
33645976866
-
Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity
-
Monsalve E., et al. Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity. J. Immunol. 176 (2006) 5362-5373
-
(2006)
J. Immunol.
, vol.176
, pp. 5362-5373
-
-
Monsalve, E.1
-
82
-
-
16244380158
-
Cyclic strain inhibits Notch receptor signaling in vascular smooth muscle cells in vitro
-
Morrow D., et al. Cyclic strain inhibits Notch receptor signaling in vascular smooth muscle cells in vitro. Circ. Res. 96 (2005) 567-575
-
(2005)
Circ. Res.
, vol.96
, pp. 567-575
-
-
Morrow, D.1
-
83
-
-
4544326176
-
Evidence for the notch signaling pathway on the role of estrogen in angiogenesis
-
Soares R., et al. Evidence for the notch signaling pathway on the role of estrogen in angiogenesis. Mol. Endocrinol. 18 (2004) 2333-2343
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 2333-2343
-
-
Soares, R.1
-
84
-
-
19044383947
-
Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis
-
Ishimura N., et al. Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis. Gastroenterology 128 (2005) 1354-1368
-
(2005)
Gastroenterology
, vol.128
, pp. 1354-1368
-
-
Ishimura, N.1
-
85
-
-
16244406228
-
Adaptive myogenesis under hypoxia
-
Yun Z., et al. Adaptive myogenesis under hypoxia. Mol. Cell. Biol. 25 (2005) 3040-3055
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 3040-3055
-
-
Yun, Z.1
-
86
-
-
0037335460
-
Glycoprotein 130 signaling regulates Notch1 expression and activation in the self-renewal of mammalian forebrain neural stem cells
-
Chojnacki A., et al. Glycoprotein 130 signaling regulates Notch1 expression and activation in the self-renewal of mammalian forebrain neural stem cells. J. Neurosci. 23 (2003) 1730-1741
-
(2003)
J. Neurosci.
, vol.23
, pp. 1730-1741
-
-
Chojnacki, A.1
-
87
-
-
0029064632
-
Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate
-
Mitsiadis T.A., et al. Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate. J. Cell Biol. 130 (1995) 407-418
-
(1995)
J. Cell Biol.
, vol.130
, pp. 407-418
-
-
Mitsiadis, T.A.1
-
88
-
-
1242351887
-
Foxf1 haploinsufficiency reduces Notch-2 signaling during mouse lung development
-
Kalinichenko V.V., et al. Foxf1 haploinsufficiency reduces Notch-2 signaling during mouse lung development. Am. J. Physiol. Lung Cell. Mol. Physiol. 286 (2004) L521-L530
-
(2004)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.286
-
-
Kalinichenko, V.V.1
-
89
-
-
0035883744
-
The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis
-
Kume T., et al. The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis. Genes Dev. 15 (2001) 2470-2482
-
(2001)
Genes Dev.
, vol.15
, pp. 2470-2482
-
-
Kume, T.1
-
90
-
-
0346654063
-
Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression
-
Raetzman L.T., et al. Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression. Dev. Biol. 265 (2004) 329-340
-
(2004)
Dev. Biol.
, vol.265
, pp. 329-340
-
-
Raetzman, L.T.1
-
91
-
-
1442307700
-
Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway
-
Gazit R., et al. Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway. Development 131 (2004) 903-913
-
(2004)
Development
, vol.131
, pp. 903-913
-
-
Gazit, R.1
-
92
-
-
1842559498
-
Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations
-
Whitehead K.J., et al. Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations. Development 131 (2004) 1437-1448
-
(2004)
Development
, vol.131
, pp. 1437-1448
-
-
Whitehead, K.J.1
-
93
-
-
0036906546
-
Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1
-
Souabni A., et al. Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1. Immunity 17 (2002) 781-793
-
(2002)
Immunity
, vol.17
, pp. 781-793
-
-
Souabni, A.1
-
94
-
-
0030850751
-
Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation
-
Saga Y., et al. Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 11 (1997) 1827-1839
-
(1997)
Genes Dev.
, vol.11
, pp. 1827-1839
-
-
Saga, Y.1
|