Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression

Developmental Biology

Volumn 265, Issue 2, 2004, Pages 329-340

  Raetzman, L T ^a   Ross, S A ^b   Cook, S ^b   Dunwoodie, S L ^c,d   Camper, S A ^a   Thomas, P Q ^b,e  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b ROYAL CHILDREN'S HOSPITAL   (Australia)

^c ST VINCENT S HOSPITAL   (Australia)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Notch signaling; Pituitary; Prop1; Rathke's pouch

Indexed keywords

NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL SELECTION; CELL SPECIFICITY; CELL TYPE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONAL TISSUE; GENE EXPRESSION REGULATION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC DISORDER; HYPOPHYSIS; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL ALLELE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STEM CELL; TRANSGENIC MOUSE;

EID: 0346654063     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2003.09.033     Document Type: Article

References (58)

1. Agarwal G., Bhatia V., Cook S., Thomas P.Q. Adrenocorticotropin deficiency in combined pituitary hormone deficiency patients homozygous for a novel PROP1 deletion. J. Clin. Endocrinol. Metab. 85:2000;4556-4561.
2. Akazawa C., Sasai Y., Nakanishi S., Kageyama R. Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system. J. Biol. Chem. 267:1992;21879-21885.
3. Apelqvist A., Li H., Sommer L., Beatus P., Anderson D.J., Honjo T., Hrabe de Angelis M., Lendahl U., Edlund H. Notch signalling controls pancreatic cell differentiation. Nature. 400:1999;877-881.
4. Artavanis-Tsakonas S., Rand M.D., Lake R.J. Notch signaling: cell fate control and signal integration in development. Science. 284:1999;770-776.
5. Bae S., Bessho Y., Hojo M., Kageyama R. The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation. Development. 127:2000;2933-2943.
6. Beatus P., Lendahl U. Notch and neurogenesis. J. Neurosci. Res. 54:1998;125-136.
7. Bulman M.P., Kusumi K., Frayling T.M., McKeown C., Garrett C., Lander E.S., Krumlauf R., Hattersley A.T., Ellard S., Turnpenny P.D. Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis. Nat. Genet. 24:2000;438-441.
8. Casarosa S., Fode C., Guillemot F. Mash1 regulates neurogenesis in the ventral telencephalon. Development. 126:1999;525-534.
9. Cossins J., Vernon A.E., Zhang Y., Philpott A., Jones P.H. Hes6 regulates myogenic differentiation. Development. 129:2002;2195-2207.
10. Cushman L.J., Watkins-Chow D.E., Brinkmeier M.L., Raetzman L.T., Radak A.L., Lloyd R.V., Camper S.A. Persistent Prop1 expression delays gonadotrope differentiation and enhances pituitary tumor susceptibility. Hum. Mol. Genet. 10:2001;1141-1153.
11. Cushman L.J., Showalter A.D., Rhodes S.J. Genetic defects in the development and function of the anterior pituitary gland. Ann. Med. 34:2002;179-191.
12. Dasen J.S., O'Connell S.M., Flynn S.E., Treier M., Gleiberman A.S., Szeto D.P., Hooshmand F., Aggarwal A.K., Rosenfeld M.G. Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. Cell. 97:1999;587-598.
13. De Bellard M.E., Ching W., Gossler A., Bronner-Fraser M. Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice. Dev. Biol. 249:2002;121-130.
14. de la Pompa J.L., Wakeham A., Correia K.M., Samper E., Brown S., Aguilera R.J., Nakano T., Honjo T., Mak T.W., Rossant J., Conlon R.A. Conservation of the Notch signalling pathway in mammalian neurogenesis. Development. 124:1997;1139-1148.
15. De Moerlooze L., Spencer-Dene B., Revest J., Hajihosseini M., Rosewell I., Dickson C. An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development. 127:2000;483-492.
16. Dunwoodie S.L., Henrique D., Harrison S.M., Beddington R.S. Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo. Development. 124:1997;3065-3076.
17. Dunwoodie S.L., Clements M., Sparrow D.B., Sa X., Conlon R.A., Beddington R.S. Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm. Development. 129:2002;1795-1806.
18. Ericson J., Norlin S., Jessell T.M., Edlund T. Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary. Development. 125:1998;1005-1015.
19. Gage P.J., Roller M.L., Saunders T.L., Scarlett L.M., Camper S.A. Anterior pituitary cells defective in the cell-autonomous factor, df, undergo cell lineage specification but not expansion. Development. 122:1996;151-160.
20. Gaiano N., Fishell G. The role of notch in promoting glial and neural stem cell fates. Annu. Rev. Neurosci. 25:2002;471-490.
21. Gao X., Chandra T., Gratton M.O., Quelo I., Prud'homme J., Stifani S., St-Arnaud R. HES6 acts as a transcriptional repressor in myoblasts and can induce the myogenic differentiation program. J. Cell Biol. 154:2001;1161-1171.
22. Hamada Y., Kadokawa Y., Okabe M., Ikawa M., Coleman J.R., Tsujimoto Y. Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Development. 126:1999;3415-3424.
23. Heitzler P., Bourouis M., Ruel L., Carteret C., Simpson P. Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila. Development. 122:1996;161-171.
24. Hrabe de Angelis M., McIntyre J. II, Gossler A. Maintenance of somite borders in mice requires the Delta homologue DII1. Nature. 386:1997;717-721.
25. Ikeda H., Yoshimoto T. Developmental changes in proliferative activity of cells of the murine Rathke's pouch. Cell Tissue Res. 263:1991;41-47.
26. Ingles-Esteve J., Espinosa L., Milner L.A., Caelles C., Bigas A. Phosphorylation of Ser2078 modulates the Notch2 function in 32D cell differentiation. J. Biol. Chem. 276:2001;44873-44880.
27. Japon M.A., Rubinstein M., Low M.J. In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. J. Histochem. Cytochem. 42:1994;1117-1125.
28. Kawamura K., Kouki T., Kawahara G., Kikuyama S. Hypophyseal development in vertebrates from amphibians to mammals. Gen. Comp. Endocrinol. 126:2002;130-135.
29. Kendall S.K., Gordon D.F., Birkmeier T.S., Petrey D., Sarapura V.D., O'Shea K.S., Wood W.M., Lloyd R.V., Ridgway E.C., Camper S.A. Enhancer-mediated high level expression of mouse pituitary glycoprotein hormone alpha-subunit transgene in thyrotropes, gonadotropes, and developing pituitary gland. Mol. Endocrinol. 8:1994;1420-1433.
30. Kiernan A.E., Ahituv N., Fuchs H., Balling R., Avraham K.B., Steel K.P., Hrabe de Angelis M. The Notch ligand Jagged1 is required for inner ear sensory development. Proc. Natl. Acad. Sci. U. S. A. 98:2001;3873-3878.
31. Kim S.K., Hebrok M. Intercellular signals regulating pancreas development and function. Genes Dev. 15:2001;111-127.
32. Koyano-Nakagawa N., Kim J., Anderson D., Kintner C. Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiation. Development. 127:2000;4203-4216.
33. Kusumi K., Sun E.S., Kerrebrock A.W., Bronson R.T., Chi D.C., Bulotsky M.S., Spencer J.B., Birren B.W., Frankel W.N., Lander E.S. The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries. Nat. Genet. 19:1998;274-278.
34. Kusumi K., Dunwoodie S.L., Krumlauf R. Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system. Mech. Dev. 100:2001;141-144.
35. Lewis J. Notch signalling and the control of cell fate choices in vertebrates. Semin. Cell Dev. Biol. 9:1998;583-589.
36. McCright B., Gao X., Shen L., Lozier J., Lan Y., Maguire M., Herzlinger D., Weinmaster G., Jiang R., Gridley T. Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 128:2001;491-502.
37. McCright B., Lozier J., Gridley T. A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. Development. 129:2002;1075-1082.
38. Ohuchi H., Hori Y., Yamasaki M., Harada H., Sekine K., Kato S., Itoh N. FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development. Biochem. Biophys. Res. Commun. 277:2000;643-649.
39. Parks J.S., Brown M.R. Transcription factors regulating pituitary development. Growth Horm. IGF Res. 9(Suppl. B):1999;2-8. (discussion 8-11).
40. Pernasetti F., Toledo S.P., Vasilyev V.V., Hayashida C.Y., Cogan J.D., Ferrari C., Lourenco D.M., Mellon P.L. Impaired adrenocorticotropin-adrenal axis in combined pituitary hormone deficiency caused by a two-base pair deletion (301-302delAG) in the prophet of Pit-1 gene. J. Clin. Endocrinol. Metab. 85:2000;390-397.
41. Przemeck G.K., Heinzmann U., Beckers J., Hrabe de Angelis M. Node and midline defects are associated with left-right development in Delta1 mutant embryos. Development. 130:2003;3-13.
42. Pulichino A., Vallette-Kasic S., Peih-Ying Tsai J., Couture C., Gauthier Y., Drouin J. Tpit determines alternate fates during pituitary cell differentiation. Genes Dev. 17:2003;738-747.
43. Raetzman L.T., Ward R., Camper S.A. Lhx4 and Prop1 are required for cell survival and expansion of the pituitary primordia. Development. 129:2002;4229-4239.
44. Scully K.M., Rosenfeld M.G. Pituitary development: regulatory codes in mammalian organogenesis. Science. 295:2002;2231-2235.
45. Shimizu K., Chiba S., Hosoya N., Kumano K., Saito T., Kurokawa M., Kanda Y., Hamada Y., Hirai H. Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2. Mol. Cell. Biol. 20:2000;6913-6922.
46. Simmons D.M., Voss J.W., Ingraham H.A., Holloway J.M., Broide R.S., Rosenfeld M.G., Swanson L.W. Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors. Genes Dev. 4:1990;695-711.
47. Sloop K.W., McCutchan Schiller A., Smith T.P., Blanton J.R. Jr., Rohrer G.A., Meier B.C., Rhodes S.J. Biochemical and genetic characterization of the porcine Prophet of Pit-1 pituitary transcription factor. Mol. Cell. Endocrinol. 168:2000;77-87.
48. Solecki D.J., Liu X.L., Tomoda T., Fang Y., Hatten M.E. Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation. Neuron. 31:2001;557-568.
49. Sornson M.W., Wu W., Dasen J.S., Flynn S.E., Norman D.J., O'Connell S.M., Gukovsky I., Carriere C., Ryan A.K., Miller A.P., Zuo L., Gleiberman A.S., Andersen B., Beamer W.G., Rosenfeld M.G. Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism. Nature. 384:1996;327-333.
50. Suh H., Gage P.J., Drouin J., Camper S.A. Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification. Development. 129:2002;329-337.
51. Tang K., Bartke A., Gardiner C.S., Wagner T.E., Yun J.S. Gonadotropin secretion, synthesis, and gene expression in human growth hormone transgenic mice and in Ames dwarf mice. Endocrinology. 132:1993;2518-2524.
52. Taniguchi Y., Kominami R., Yasutaka S., Kawarai Y. Proliferation and differentiation of pituitary corticotrophs during the fetal and postnatal period: a quantitative immunocytochemical study. Anat. Embryol. 201:2000;229-234.
53. Taniguchi Y., Yasutaka S., Kominami R., Shinohara H. Proliferation and differentiation of pituitary somatotrophs and mammotrophs during late fetal and postnatal periods. Anat. Embryol. 204:2001;469-475.
54. Tomita K., Ishibashi M., Nakahara K., Ang S.L., Nakanishi S., Guillemot F., Kageyama R. Mammalian hairy and Enhancer of split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis. Neuron. 16:1996;723-734.
55. Treier M., Gleiberman A.S., O'Connell S.M., Szeto D.P., McMahon J.A., McMahon A.P., Rosenfeld M.G. Multistep signaling requirements for pituitary organogenesis in vivo. Genes Dev. 12:1998;1691-1704.
56. Treier M., O'Connell S., Gleiberman A., Price J., Szeto D.P., Burgess R., Chuang P.T., McMahon A.P., Rosenfeld M.G. Hedgehog signaling is required for pituitary gland development. Development. 128:2001;377-386.
57. Vasiliauskas D., Stern C.D. Expression of mouse HES-6, a new member of the Hairy/Enhancer of split family of bHLH transcription factors. Mech. Dev. 98:2000;133-137.
58. Wu W., Cogan J.D., Pfaffle R.W., Dasen J.S., Frisch H., O'Connell S.M., Flynn S.E., Brown M.R., Mullis P.E., Parks J.S., Phillips J.A. III, Rosenfeld M.G. Mutations in PROP1 cause familial combined pituitary hormone deficiency. Nat. Genet. 18:1998;147-149.