메뉴 건너뛰기




Volumn 54, Issue 3, 2007, Pages 201-235

Pathogenicity and drug resistance in Candida albicans and other yeast species

Author keywords

ABC transporters; Biofilm; Candida; Drug resistance; Efflux pump; Efflux pumps

Indexed keywords

CANDIDA; CANDIDA ALBICANS;

EID: 34548429972     PISSN: 12178950     EISSN: 15882640     Source Type: Journal    
DOI: 10.1556/AMicr.54.2007.3.1     Document Type: Review
Times cited : (153)

References (154)
  • 1
    • 0036904129 scopus 로고    scopus 로고
    • Garlic (Allium sativam) as an anti-Candida agent: A comparison of the efficacy of fresh garlic and freeze-dried extracts
    • Lemar, K. M., Turner, M. P., Lloyd, D.: Garlic (Allium sativam) as an anti-Candida agent: a comparison of the efficacy of fresh garlic and freeze-dried extracts. J Appl Microbiol 93, 398-405 (2002).
    • (2002) J Appl Microbiol , vol.93 , pp. 398-405
    • Lemar, K.M.1    Turner, M.P.2    Lloyd, D.3
  • 2
    • 2942705969 scopus 로고    scopus 로고
    • Candida and Candidiasis: The cell wall as a potential molecular target for antifungal therapy
    • Gozalbo, D., Roig, P., Villamón, E., Gil, M. L.: Candida and Candidiasis: The cell wall as a potential molecular target for antifungal therapy. Curr Drug Targets Infect Disord 4, 117-135 (2004).
    • (2004) Curr Drug Targets Infect Disord , vol.4 , pp. 117-135
    • Gozalbo, D.1    Roig, P.2    Villamón, E.3    Gil, M.L.4
  • 3
    • 10444285332 scopus 로고    scopus 로고
    • Multidrug resistance in yeast Candida
    • Prasad, R., Kapoor, K.: Multidrug resistance in yeast Candida. Int Rev Cyt 242, 215-248 (2005).
    • (2005) Int Rev Cyt , vol.242 , pp. 215-248
    • Prasad, R.1    Kapoor, K.2
  • 5
    • 0032311182 scopus 로고    scopus 로고
    • Antibody and/or cell-mediated immunity, protective mechanisms in fungal disease: An ongoing dilemma or an unnecessary dispute
    • Casadevall, A Cassone, A., Bistoni, F., Cutler, J. E., Magliani, W., Murphy, J. W., Polonelli, L., Romani, L.: Antibody and/or cell-mediated immunity, protective mechanisms in fungal disease: An ongoing dilemma or an unnecessary dispute. Med Mycol 36, 95-105 (1998).
    • (1998) Med Mycol , vol.36 , pp. 95-105
    • Casadevall, A.1    Cassone, A.2    Bistoni, F.3    Cutler, J.E.4    Magliani, W.5    Murphy, J.W.6    Polonelli, L.7    Romani, L.8
  • 6
    • 1542674589 scopus 로고    scopus 로고
    • Immunity to fungal infections
    • Romani, L.: Immunity to fungal infections. Nat Rev Immunol 4, 1-13 (2004).
    • (2004) Nat Rev Immunol , vol.4 , pp. 1-13
    • Romani, L.1
  • 7
    • 0025989934 scopus 로고
    • Putative virulence factors of Candida albicans
    • Cutler, J. E.: Putative virulence factors of Candida albicans. Annu Rev Microbiol 45, 187-218 (1991).
    • (1991) Annu Rev Microbiol , vol.45 , pp. 187-218
    • Cutler, J.E.1
  • 10
    • 0031984061 scopus 로고    scopus 로고
    • Serologic; response to cell wall mannoproteins and proteins of Candida albicans
    • Martínez, J. P. Gil, M. L., López-Ribot M. L., Chaffin, W. L.: Serologic; response to cell wall mannoproteins and proteins of Candida albicans. Clin Microbiol Rev 11, 121-141 (1998).
    • (1998) Clin Microbiol Rev , vol.11 , pp. 121-141
    • Martínez, J.P.1    Gil, M.L.2    López-Ribot, M.L.3    Chaffin, W.L.4
  • 11
    • 0026515061 scopus 로고
    • High-frequency switching in Candida albicans
    • Soll, D. R.: High-frequency switching in Candida albicans. Clin Microbiol Rev 5, 183-203 (1992).
    • (1992) Clin Microbiol Rev , vol.5 , pp. 183-203
    • Soll, D.R.1
  • 12
    • 0141789642 scopus 로고    scopus 로고
    • Candida albicans secreted aspartyl proteinases in virulence and pathogenesis
    • Naglik, J. R., Challacombe, S. J., Hube, B.: Candida albicans secreted aspartyl proteinases in virulence and pathogenesis. Microbiol Mol Biol Rev 67, 400-428 (2003).
    • (2003) Microbiol Mol Biol Rev , vol.67 , pp. 400-428
    • Naglik, J.R.1    Challacombe, S.J.2    Hube, B.3
  • 13
    • 0032775156 scopus 로고    scopus 로고
    • Regulatory networks controlling Candida albicans morphogenesis
    • Brown, A. J., Gow, N. A. R.: Regulatory networks controlling Candida albicans morphogenesis. Trends Microbiol 7, 333-338 (1999).
    • (1999) Trends Microbiol , vol.7 , pp. 333-338
    • Brown, A.J.1    Gow, N.A.R.2
  • 14
    • 0033870274 scopus 로고    scopus 로고
    • Transcription factors in Candida albicans - environmental control of morphogenesis
    • Ernst, J.: Transcription factors in Candida albicans - environmental control of morphogenesis. Microbiol 146, 1763-1774 (2000).
    • (2000) Microbiol , vol.146 , pp. 1763-1774
    • Ernst, J.1
  • 15
    • 0031042323 scopus 로고    scopus 로고
    • Gene regulation during high-frequency switching in Candida albicans
    • Soll, D. R.: Gene regulation during high-frequency switching in Candida albicans. Microbiol 143, 279-288 (1997).
    • (1997) Microbiol , vol.143 , pp. 279-288
    • Soll, D.R.1
  • 16
    • 0025989934 scopus 로고
    • Putative virulence factors of Candida albicans
    • Cutler, J. E.: Putative virulence factors of Candida albicans. Annu Rev Microbiol 45, 187-218 (1991).
    • (1991) Annu Rev Microbiol , vol.45 , pp. 187-218
    • Cutler, J.E.1
  • 18
    • 0004046690 scopus 로고
    • Eds. Gow, N. A. R, Gadd, G. M. Chapman and Hall, London
    • Gooday, G. W., in: The Growing Fungus. Eds. Gow, N. A. R., Gadd, G. M. Chapman and Hall, London, 41-74 (1995).
    • (1995) The Growing Fungus , pp. 41-74
    • Gooday, G.W.1
  • 19
    • 0027173916 scopus 로고
    • Immunological activities of a Candida albicans protein which plays an important role in the survival of the microorganism in the host
    • Tavares, D., Salvador, A., Ferreira, P., Arala-Chaves, M. P.: Immunological activities of a Candida albicans protein which plays an important role in the survival of the microorganism in the host Infect Immun 61, 1881 (1993).
    • (1993) Infect Immun , vol.61 , pp. 1881
    • Tavares, D.1    Salvador, A.2    Ferreira, P.3    Arala-Chaves, M.P.4
  • 20
    • 0030055322 scopus 로고    scopus 로고
    • Induction of an extracellular esterase from Candida albicans and some of its properties
    • Tsuboi, R., Komatsuzaki, H., Ogawa, H.: Induction of an extracellular esterase from Candida albicans and some of its properties. Infect Immun 64, 2936 (1996).
    • (1996) Infect Immun , vol.64 , pp. 2936
    • Tsuboi, R.1    Komatsuzaki, H.2    Ogawa, H.3
  • 21
    • 0032823710 scopus 로고    scopus 로고
    • Identification and cloning of GCA1, a gene which encodes a cell wall glucoamylase from Candida albicans
    • Sturtevant, J., Dixon, F., Wadsworth, E., Latge, J. P., Zhao, X. J., Calderone, R.: Identification and cloning of GCA1, a gene which encodes a cell wall glucoamylase from Candida albicans. Med Mycol 37, 357-366 (1999).
    • (1999) Med Mycol , vol.37 , pp. 357-366
    • Sturtevant, J.1    Dixon, F.2    Wadsworth, E.3    Latge, J.P.4    Zhao, X.J.5    Calderone, R.6
  • 22
    • 0003026325 scopus 로고
    • Eds. Bennet, J. E, Hay, R. J, Peterson, P. K. Churchill. Livingstone Inc, New York
    • Douglas, L. J., in: New Strategies in Fungal Disease. Eds. Bennet, J. E., Hay, R. J., Peterson, P. K. Churchill. Livingstone Inc, New York, 34-50 (1992).
    • (1992) New Strategies in Fungal Disease , pp. 34-50
    • Douglas, L.J.1
  • 23
    • 0027222876 scopus 로고
    • Recognition between Candida albicans and host cells
    • Calderone, R. A.: Recognition between Candida albicans and host cells. Trends Microbiol 1, 55-58 (1993).
    • (1993) Trends Microbiol , vol.1 , pp. 55-58
    • Calderone, R.A.1
  • 25
    • 0028233714 scopus 로고
    • Plasma and extracellular matrix proteins mediate in the fate of Candida albicans in the human host
    • Klotz, S. A.: Plasma and extracellular matrix proteins mediate in the fate of Candida albicans in the human host. Medical Hypotheses 42, 328-334 (1994).
    • (1994) Medical Hypotheses , vol.42 , pp. 328-334
    • Klotz, S.A.1
  • 26
    • 0033501266 scopus 로고    scopus 로고
    • Integrin-like proteins in Candida spp. and other microorganisms
    • Hostetter, M. K.: Integrin-like proteins in Candida spp. and other microorganisms. Fungal Genet Biol 28, 135-145 (1999).
    • (1999) Fungal Genet Biol , vol.28 , pp. 135-145
    • Hostetter, M.K.1
  • 27
    • 79961218159 scopus 로고    scopus 로고
    • Molecular basis of adhesion of Candida albicans
    • Fukazawa, Y., Kagaya, K.: Molecular basis of adhesion of Candida albicans. J Med Vet Mycol 35, 87-99 (1997).
    • (1997) J Med Vet Mycol , vol.35 , pp. 87-99
    • Fukazawa, Y.1    Kagaya, K.2
  • 28
    • 0028098182 scopus 로고
    • Adhesins and ligands involved in the interaction of Candida spp. with epithelial and endothelial surfaces
    • Hostetter, M.: Adhesins and ligands involved in the interaction of Candida spp. with epithelial and endothelial surfaces. Clin Microbiol Rev 7, 29-42 (1994).
    • (1994) Clin Microbiol Rev , vol.7 , pp. 29-42
    • Hostetter, M.1
  • 29
    • 0034921156 scopus 로고    scopus 로고
    • Different adhesins for type IV collagen on Candida albicans: Identification of a lectin-like adhesin recognizing the 7S(IV) domain
    • Alonso, R., Lopis, I., Flores, C., Murgui, A., Timoneda, J.: Different adhesins for type IV collagen on Candida albicans: Identification of a lectin-like adhesin recognizing the 7S(IV) domain. Microbiol 147, 1971-1981 (2001).
    • (2001) Microbiol , vol.147 , pp. 1971-1981
    • Alonso, R.1    Lopis, I.2    Flores, C.3    Murgui, A.4    Timoneda, J.5
  • 30
    • 0036007236 scopus 로고    scopus 로고
    • Holmes, A. R., Bandara, B. M., Cannon, R. D.: Saliva promotes Candida albicans adherence to human epithelial cells. J Dent Res 81, 28-32 (2002).
    • Holmes, A. R., Bandara, B. M., Cannon, R. D.: Saliva promotes Candida albicans adherence to human epithelial cells. J Dent Res 81, 28-32 (2002).
  • 32
    • 0032570872 scopus 로고    scopus 로고
    • Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1
    • Gale, C. A. Bendel, C. M., McClellan, M., Hauser, M., Becker, J. M., Berman, J., Hostetter, M. K.: Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1. Science 279, 1355-1358 (1998).
    • (1998) Science , vol.279 , pp. 1355-1358
    • Gale, C.A.1    Bendel, C.M.2    McClellan, M.3    Hauser, M.4    Becker, J.M.5    Berman, J.6    Hostetter, M.K.7
  • 33
    • 0037344772 scopus 로고    scopus 로고
    • Candida albicans binds human plasminogen: Identification of eight plasminogen-binding proteins
    • Crowe, J. D., Sievwright, I. K., Auld, G. C., Moore, N. R., Gow, N. A. R., Booth, N. A.: Candida albicans binds human plasminogen: Identification of eight plasminogen-binding proteins. Mol Mcrobiol 47, 1637-1651 (2003).
    • (2003) Mol Mcrobiol , vol.47 , pp. 1637-1651
    • Crowe, J.D.1    Sievwright, I.K.2    Auld, G.C.3    Moore, N.R.4    Gow, N.A.R.5    Booth, N.A.6
  • 34
    • 0035313659 scopus 로고    scopus 로고
    • The ALS gene family of Candida albicans
    • Hoyer, L. L.: The ALS gene family of Candida albicans. Trends Microbiol 9, 176-180 (2001).
    • (2001) Trends Microbiol , vol.9 , pp. 176-180
    • Hoyer, L.L.1
  • 35
    • 0036670881 scopus 로고    scopus 로고
    • Adhesion in Candida spp
    • Sundstrom, P.: Adhesion in Candida spp. Cell Microbiol 4, 461-469 (2002).
    • (2002) Cell Microbiol , vol.4 , pp. 461-469
    • Sundstrom, P.1
  • 36
    • 0036460205 scopus 로고    scopus 로고
    • Candida albicans and Saccharomyces cerevisiae expressing ALA1/ALS5 adhere to accessible threonine, serine or alanine patches
    • Gaur, N. K. Smith, R. L., Klotz, S. A.: Candida albicans and Saccharomyces cerevisiae expressing ALA1/ALS5 adhere to accessible threonine, serine or alanine patches. Cell Commun Adhes 9, 45-57 (2002).
    • (2002) Cell Commun Adhes , vol.9 , pp. 45-57
    • Gaur, N.K.1    Smith, R.L.2    Klotz, S.A.3
  • 37
    • 0345391036 scopus 로고    scopus 로고
    • Adhesive and mammalian transglutaminase substrate properties of Candida albicans HWP1
    • Staab, J. F., Bradway, S. D., Fidel, P. L., Sundstrom, P.: Adhesive and mammalian transglutaminase substrate properties of Candida albicans HWP1. Science 283, 1535-1538 (1999).
    • (1999) Science , vol.283 , pp. 1535-1538
    • Staab, J.F.1    Bradway, S.D.2    Fidel, P.L.3    Sundstrom, P.4
  • 39
    • 0344875496 scopus 로고    scopus 로고
    • The adhesin HWP1 and the first daughter cell localize to the a/ a portion of the conjugation bridge during Candidda albicans mating
    • Daniels, K. J., Lockhart, S. R., Staab, J. F., Sundstrom, P., Soll, D. R.: The adhesin HWP1 and the first daughter cell localize to the a/ a portion of the conjugation bridge during Candidda albicans mating. Mol Biol Cell 14, 4920-4930 (2003).
    • (2003) Mol Biol Cell , vol.14 , pp. 4920-4930
    • Daniels, K.J.1    Lockhart, S.R.2    Staab, J.F.3    Sundstrom, P.4    Soll, D.R.5
  • 43
    • 0141495001 scopus 로고    scopus 로고
    • Fungal β-glucans and mammalian immunity
    • Brown, G. D., Gordon, S.: Fungal β-glucans and mammalian immunity. Immunity 19, 311-315 (2003).
    • (2003) Immunity , vol.19 , pp. 311-315
    • Brown, G.D.1    Gordon, S.2
  • 45
    • 1842407144 scopus 로고    scopus 로고
    • Prospects for the development of fungal vaccines
    • Deepe, G. S. Jr.: Prospects for the development of fungal vaccines. Clin Microbiol Rev 10, 585-596 (1997).
    • (1997) Clin Microbiol Rev , vol.10 , pp. 585-596
    • Deepe Jr., G.S.1
  • 46
    • 0033977536 scopus 로고    scopus 로고
    • Biochemical and immunological characterization of MP65, a major mannoprotein antigen of the opportunistic human pathogen Candida albicans
    • Gomez, M. J., Maras, B., Barca, A., La Valle, L., Barra, D., Cassone, A.: Biochemical and immunological characterization of MP65, a major mannoprotein antigen of the opportunistic human pathogen Candida albicans. Infect Immun 68, 694-701 (2000).
    • (2000) Infect Immun , vol.68 , pp. 694-701
    • Gomez, M.J.1    Maras, B.2    Barca, A.3    La Valle, L.4    Barra, D.5    Cassone, A.6
  • 47
    • 0035001262 scopus 로고    scopus 로고
    • Antigenic properties and processing requirements of 65 kDa mannoprotein, a major antigen target of anti-Candida human T-cell response, as disclosed by specific human T-cell clones
    • Nisini, R., Romagnoli, G., Gomez, M. J., La Valle, R., Torosantucci, A., Mariotti, S., Teloni, R., Cassone, A.: Antigenic properties and processing requirements of 65 kDa mannoprotein, a major antigen target of anti-Candida human T-cell response, as disclosed by specific human T-cell clones. Infect Immun 69, 3728-3736 (2001).
    • (2001) Infect Immun , vol.69 , pp. 3728-3736
    • Nisini, R.1    Romagnoli, G.2    Gomez, M.J.3    La Valle, R.4    Torosantucci, A.5    Mariotti, S.6    Teloni, R.7    Cassone, A.8
  • 49
    • 0036756090 scopus 로고    scopus 로고
    • Medical importance of biofilms in Candida infections
    • Douglas, L. J.: Medical importance of biofilms in Candida infections. Rev Iberoam Micol 19, 139-143 (2002).
    • (2002) Rev Iberoam Micol , vol.19 , pp. 139-143
    • Douglas, L.J.1
  • 50
    • 0036196019 scopus 로고    scopus 로고
    • Mixed species biofilms of Candida albicans and Staphylococcus epidermidis
    • Adam, B., Baillie, G. S., Douglas, L. J.: Mixed species biofilms of Candida albicans and Staphylococcus epidermidis. J Med Microbiol 51, 344-349 (2002).
    • (2002) J Med Microbiol , vol.51 , pp. 344-349
    • Adam, B.1    Baillie, G.S.2    Douglas, L.J.3
  • 51
    • 0034443286 scopus 로고    scopus 로고
    • Microbial biofilms: From ecology to molecular genetics
    • Davey, M. E., O'Toole, G. A.: Microbial biofilms: From ecology to molecular genetics. Microbiol Mol Biol Rev 64, 847-867 (2000).
    • (2000) Microbiol Mol Biol Rev , vol.64 , pp. 847-867
    • Davey, M.E.1    O'Toole, G.A.2
  • 52
    • 0037230342 scopus 로고    scopus 로고
    • Candida biofilms and their role in infection
    • Douglas, L. J.: Candida biofilms and their role in infection. Trends Microbiol 11, 30-36 (2003).
    • (2003) Trends Microbiol , vol.11 , pp. 30-36
    • Douglas, L.J.1
  • 53
    • 0036711963 scopus 로고    scopus 로고
    • Biofilms: Microbial life on surfaces
    • Donlan, R. M.: Biofilms: Microbial life on surfaces. Emerg Infect Dis 8, 1-19 (2002).
    • (2002) Emerg Infect Dis , vol.8 , pp. 1-19
    • Donlan, R.M.1
  • 54
    • 0035077009 scopus 로고    scopus 로고
    • Riddle of biofilm resistance
    • Lewis, K.: Riddle of biofilm resistance. Antimicrob Agents Chemother 45, 999-1007 (2001).
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 999-1007
    • Lewis, K.1
  • 56
    • 0035014383 scopus 로고    scopus 로고
    • Mechanisms of biofilm resistance to antimicrobial agents
    • Mah, T.-F. C., O'Toole, G. A.: Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol 9, 34-39 (2001).
    • (2001) Trends Microbiol , vol.9 , pp. 34-39
    • Mah, T.-F.C.1    O'Toole, G.A.2
  • 57
    • 0033824935 scopus 로고    scopus 로고
    • Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents
    • Baillie, G. S., Douglas, L. J.: Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents. J Antimicrob Chemother 46, 397-403 (2000).
    • (2000) J Antimicrob Chemother , vol.46 , pp. 397-403
    • Baillie, G.S.1    Douglas, L.J.2
  • 58
    • 0031927421 scopus 로고    scopus 로고
    • Iron-limited biofilms of Candida albicans and their susceptibility to amphotericin B
    • Baillie, G. S., Douglas, L. J.: Iron-limited biofilms of Candida albicans and their susceptibility to amphotericin B. Antimicrob Agents Chemother 42, 2146-2149 (1998).
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 2146-2149
    • Baillie, G.S.1    Douglas, L.J.2
  • 59
    • 0031926750 scopus 로고    scopus 로고
    • Effect of growth rate on resistance of Candida albicans biofilms to antifungal agents
    • Baillie, G. S., Douglas, L. J.: Effect of growth rate on resistance of Candida albicans biofilms to antifungal agents. Antimicrob Agents Chemother 42, 1900-1905 (1998).
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1900-1905
    • Baillie, G.S.1    Douglas, L.J.2
  • 60
    • 0036228505 scopus 로고    scopus 로고
    • Biofilms: Survival mechanisms of clinically relevant microorganisms
    • Donlan, R. M., Costerton, J. W.: Biofilms: Survival mechanisms of clinically relevant microorganisms. Clin Microbiol Rev 15, 167-193 (2002).
    • (2002) Clin Microbiol Rev , vol.15 , pp. 167-193
    • Donlan, R.M.1    Costerton, J.W.2
  • 61
    • 0034019747 scopus 로고    scopus 로고
    • Expression of the multiple antibiotic resistance operon (mar) during growth of Escherichia coli as a biofilm
    • Maira-Litran, T.: Expression of the multiple antibiotic resistance operon (mar) during growth of Escherichia coli as a biofilm. J Appl Microbiol 88, 243-247 (2000).
    • (2000) J Appl Microbiol , vol.88 , pp. 243-247
    • Maira-Litran, T.1
  • 62
    • 0034002551 scopus 로고    scopus 로고
    • A dose-response study of antibiotic resistance in Pseudomonas aeruginosa biofilms
    • Brooun, A.: A dose-response study of antibiotic resistance in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother 44, 640-646 (2000).
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 640-646
    • Brooun, A.1
  • 63
    • 0035992139 scopus 로고    scopus 로고
    • Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms
    • Ramage, G. et al.: Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms. J Antimicrob Chemother 49, 973-980 (2002).
    • (2002) J Antimicrob Chemother , vol.49 , pp. 973-980
    • Ramage, G.1
  • 64
    • 0031969879 scopus 로고    scopus 로고
    • Clinical, cellular, and molecular factors that contribute to antifungal drug resistance
    • 11382 11402
    • White, T. C., Kieren, A. M., Bowden, R. A.: Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin Microbiol Rev 11382-11402 (1998).
    • (1998) Clin Microbiol Rev
    • White, T.C.1    Kieren, A.M.2    Bowden, R.A.3
  • 65
    • 0026073186 scopus 로고
    • Genetic mechanisms of drug resistance. A review
    • Borst, P.: Genetic mechanisms of drug resistance. A review, Acta Oncologica 30, 87-105 (1991).
    • (1991) Acta Oncologica , vol.30 , pp. 87-105
    • Borst, P.1
  • 66
    • 0027730156 scopus 로고
    • Resistance of Candida albicans to azole antifungal agents
    • Hitchcock, C. A.: Resistance of Candida albicans to azole antifungal agents. Biochem Soc Trans 21, 1039-1047 (1993).
    • (1993) Biochem Soc Trans , vol.21 , pp. 1039-1047
    • Hitchcock, C.A.1
  • 68
    • 0030025637 scopus 로고    scopus 로고
    • Correlation between rhodamine 123 accumulation and azole sensitivity in Candida species - possible role for drug efflux in drug resistance
    • Clark, F. S., Parkinson, T., Hitchcock, C. A., Gow, N. A. R.: Correlation between rhodamine 123 accumulation and azole sensitivity in Candida species - possible role for drug efflux in drug resistance. Antimicrob Agents Chemother 40, 419-425 (1996).
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 419-425
    • Clark, F.S.1    Parkinson, T.2    Hitchcock, C.A.3    Gow, N.A.R.4
  • 69
    • 0028942449 scopus 로고
    • Mode of action and resistance to azole antifungals associated with the formation of 14α-methylergosta-8,24-dien-3-beta,6-α-diol
    • Kelly, S. L., Lamb, D. C., Corran, A. J., Baldwin, B. C., Kelly, D. E.: Mode of action and resistance to azole antifungals associated with the formation of 14α-methylergosta-8,24-dien-3-beta,6-α-diol. Biochem Biophys Res Commun 207, 910-915 (1995).
    • (1995) Biochem Biophys Res Commun , vol.207 , pp. 910-915
    • Kelly, S.L.1    Lamb, D.C.2    Corran, A.J.3    Baldwin, B.C.4    Kelly, D.E.5
  • 70
    • 0026718664 scopus 로고
    • Increased sensitivity of Candida albicans cells accumulating l4α-methylated sterols to active oxygen: Possible relevance to in vivo efficacies of azole antifungal agents
    • Shimokawa, O., Nakayama, H.: Increased sensitivity of Candida albicans cells accumulating l4α-methylated sterols to active oxygen: Possible relevance to in vivo efficacies of azole antifungal agents. Antimicrob Agents Chemother 36, 1626-1629 (1992).
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 1626-1629
    • Shimokawa, O.1    Nakayama, H.2
  • 71
    • 0001917317 scopus 로고
    • Ergosterol biosynthesis inhibitors
    • R. Prasad ed, Springer-Verlag KG, Berlin, Germany
    • Vanden Bossche, H.: Ergosterol biosynthesis inhibitors. In: R. Prasad (ed.), Candida albicans. Springer-Verlag KG, Berlin, Germany, 239-257 (1991).
    • (1991) Candida albicans , pp. 239-257
    • Vanden Bossche, H.1
  • 72
    • 0027360859 scopus 로고
    • Sterol synthesis and viability of erg11 (cytochrome P450 lanosterol demethylase) mutations in Saccharomyces cerevisiae and Candida albicans
    • Bard, M., Lees, N. D., Craft T. D., Cofrin, L., Barbuch, R., Koegel, C., Loper, J. C.: Sterol synthesis and viability of erg11 (cytochrome P450 lanosterol demethylase) mutations in Saccharomyces cerevisiae and Candida albicans. Lipids 28, 963-967 (1993).
    • (1993) Lipids , vol.28 , pp. 963-967
    • Bard, M.1    Lees, N.D.2    Craft, T.D.3    Cofrin, L.4    Barbuch, R.5    Koegel, C.6    Loper, J.C.7
  • 73
    • 0024468971 scopus 로고
    • Defective sterol C5-6 desaturation and azole resistance: A new hypothesis for the mode of action of azole antifungals
    • Watson, P. F., Rose, M. E., Ellis, S. W., England, H., Kelly, S. L.: Defective sterol C5-6 desaturation and azole resistance: A new hypothesis for the mode of action of azole antifungals. Biochem Biophys Res Commun 164, 1170-1175 (1989).
    • (1989) Biochem Biophys Res Commun , vol.164 , pp. 1170-1175
    • Watson, P.F.1    Rose, M.E.2    Ellis, S.W.3    England, H.4    Kelly, S.L.5
  • 75
    • 0031024163 scopus 로고    scopus 로고
    • Resistance to fluconazole and crossresistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol Δ(5,6) desaturation
    • Kelly, S. L., Lamb, D. C., Kelly, D., Manning, E. N. J., Loeffler, H., Hebart, J., Schumacher U., Einsele, H.: Resistance to fluconazole and crossresistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol Δ(5,6) desaturation. FEBS Lett 400, 80-82 (1997).
    • (1997) FEBS Lett , vol.400 , pp. 80-82
    • Kelly, S.L.1    Lamb, D.C.2    Kelly, D.3    Manning, E.N.J.4    Loeffler, H.5    Hebart, J.6    Schumacher, U.7    Einsele, H.8
  • 76
    • 0027441959 scopus 로고
    • Effects of itraconazole on cytochrome P-450-dependent sterol 14α-demethylation and reduction of 3-ketosteroids in Cryptococcus neoformans
    • Vanden Bossche, H., Marichal, L., Le Jeune, P., Coene, M. C. Gorrens, J., Cools, W.: Effects of itraconazole on cytochrome P-450-dependent sterol 14α-demethylation and reduction of 3-ketosteroids in Cryptococcus neoformans. Antimicrob Agents Chemother 37, 2101-2105 (1993).
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 2101-2105
    • Vanden Bossche, H.1    Marichal, L.2    Le Jeune, P.3    Coene, M.C.4    Gorrens, J.5    Cools, W.6
  • 78
    • 0031054924 scopus 로고    scopus 로고
    • The mutation T315A in Candida albicans sterol 14α-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity
    • Lamb, D. C., Kelly, D. E., Schunck, W. H., Shyadehi, A. Z., Akhtar, M., Lowe, D. J., Baldwin, B. C., Kelly, S. L.: The mutation T315A in Candida albicans sterol 14α-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity. J Biol Chem 272, 5682-5688 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 5682-5688
    • Lamb, D.C.1    Kelly, D.E.2    Schunck, W.H.3    Shyadehi, A.Z.4    Akhtar, M.5    Lowe, D.J.6    Baldwin, B.C.7    Kelly, S.L.8
  • 79
    • 79961221512 scopus 로고    scopus 로고
    • Inhibition and interaction of cytochrome P450 of Candida krusei with azole antifungal drugs
    • Venkateswarlu, K., Denning, D. W., Kelly, S. L.: Inhibition and interaction of cytochrome P450 of Candida krusei with azole antifungal drugs. J Med Vet Mycol 35, 19-25 (1997).
    • (1997) J Med Vet Mycol , vol.35 , pp. 19-25
    • Venkateswarlu, K.1    Denning, D.W.2    Kelly, S.L.3
  • 80
    • 0025304406 scopus 로고
    • Azole susceptibility and hyphal formation in a cytochrome P450-deficient mutant of Candida albicans
    • Lees, N. D., Broughton, M. C., Sanglard, D., Bard, M.: Azole susceptibility and hyphal formation in a cytochrome P450-deficient mutant of Candida albicans. Antimicrob Agents Chemother 34, 831-836 (1990).
    • (1990) Antimicrob Agents Chemother , vol.34 , pp. 831-836
    • Lees, N.D.1    Broughton, M.C.2    Sanglard, D.3    Bard, M.4
  • 81
    • 0025989934 scopus 로고
    • Putative virulence factors of Candida albicans
    • Cutler, J. E.: Putative virulence factors of Candida albicans. Annu Rev Microbiol 45, 187-218 (1991).
    • (1991) Annu Rev Microbiol , vol.45 , pp. 187-218
    • Cutler, J.E.1
  • 83
    • 0030998109 scopus 로고    scopus 로고
    • Molecular mechanisms of azole resistance in fungi
    • Joseph-Horne, T., Hollomon, D. W.: Molecular mechanisms of azole resistance in fungi. FEMS Microbiol Lett 149, 141-149 (1997).
    • (1997) FEMS Microbiol Lett , vol.149 , pp. 141-149
    • Joseph-Horne, T.1    Hollomon, D.W.2
  • 84
    • 0023753791 scopus 로고    scopus 로고
    • Ishida, N., Aoyama, Y., Hatanaka, R., Oyama, Y., Imajo, S., Ishiguro, M., Oshima, T., Nakazato, H , Noguchi, T., Maitra, U. S., Mohan, V. P., Sprinson, D. B., Shida, Y.: A single amino acid substitution converts cytochrome P450(14DM) to an inactive form, cytochrome P450SG1: Complete primary structures deduced from cloned DNAS. Biochem Biophys Res Commun 155, 317-323 (1988).
    • Ishida, N., Aoyama, Y., Hatanaka, R., Oyama, Y., Imajo, S., Ishiguro, M., Oshima, T., Nakazato, H , Noguchi, T., Maitra, U. S., Mohan, V. P., Sprinson, D. B., Shida, Y.: A single amino acid substitution converts cytochrome P450(14DM) to an inactive form, cytochrome P450SG1: Complete primary structures deduced from cloned DNAS. Biochem Biophys Res Commun 155, 317-323 (1988).
  • 85
    • 0022360764 scopus 로고
    • Spectral properties of a novel cytochrome P450 of a Saccharomyces cerevisiae mutant SG1, a cytochrome P450 species having a nitrogenous ligand trans to thiolate
    • Yoshida, Y., Aoyama, Y., Nishino, T., Katsuki, H., Maitra, U. S., Mohan, V. P., Sprinson, D. B.: Spectral properties of a novel cytochrome P450 of a Saccharomyces cerevisiae mutant SG1, a cytochrome P450 species having a nitrogenous ligand trans to thiolate. Biochem Biophys Res Commun 127, 623-628 (1985).
    • (1985) Biochem Biophys Res Commun , vol.127 , pp. 623-628
    • Yoshida, Y.1    Aoyama, Y.2    Nishino, T.3    Katsuki, H.4    Maitra, U.S.5    Mohan, V.P.6    Sprinson, D.B.7
  • 88
    • 0029954699 scopus 로고    scopus 로고
    • The mechanism of the acyl-carbon bond cleavage reaction catalyzed by recombinant sterol 14α-demethylase of Candida albicans (other names are lanosterol 14α-demethylase, P-450(14DM) and CYP51)
    • Shyadehi, A. Z., Lamb, D. C., Kelly, S. L., Kelly, D. E., Schunck, W. H., Wright J. N., Corina, D., Akhtar, M.: The mechanism of the acyl-carbon bond cleavage reaction catalyzed by recombinant sterol 14α-demethylase of Candida albicans (other names are lanosterol 14α-demethylase, P-450(14DM) and CYP51). J Biol Chem 271, 12445-12450 (1996).
    • (1996) J Biol Chem , vol.271 , pp. 12445-12450
    • Shyadehi, A.Z.1    Lamb, D.C.2    Kelly, S.L.3    Kelly, D.E.4    Schunck, W.H.5    Wright, J.N.6    Corina, D.7    Akhtar, M.8
  • 89
    • 0030998617 scopus 로고    scopus 로고
    • Characterization of Saccharomyces cerevisiae CYP51 and a CYP51 fusion protein with NADPH cytochrome P-450 oxidoreductase expressed in Escherichia coli
    • Venkateswarlu, K., Kelly, D. E., Kelly, S. L.: Characterization of Saccharomyces cerevisiae CYP51 and a CYP51 fusion protein with NADPH cytochrome P-450 oxidoreductase expressed in Escherichia coli. Antimicrob Agents-Chemother 41, 776-780 (1997).
    • (1997) Antimicrob Agents-Chemother , vol.41 , pp. 776-780
    • Venkateswarlu, K.1    Kelly, D.E.2    Kelly, S.L.3
  • 90
    • 0031938057 scopus 로고    scopus 로고
    • Amino acid substitutions in the cytochrome P450 lanosterol 14α-demethylase ( CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents
    • Sanglard, D., Ischer, F., Koymans, L., Bille, J.: Amino acid substitutions in the cytochrome P450 lanosterol 14α-demethylase ( CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents. Antimicrob Agents Chemother 42, 241-253 (1998).
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 241-253
    • Sanglard, D.1    Ischer, F.2    Koymans, L.3    Bille, J.4
  • 91
    • 0029853191 scopus 로고    scopus 로고
    • Multiple efflux mechanisms are involved in Candida albicans fluconazole resistance
    • Albertson, G. D., Niimi, M., Cannon, R. D., Jenkinson, H. F.: Multiple efflux mechanisms are involved in Candida albicans fluconazole resistance. Antimicrob Agents Chemother 40, 2835-2841 (1996).
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 2835-2841
    • Albertson, G.D.1    Niimi, M.2    Cannon, R.D.3    Jenkinson, H.F.4
  • 92
    • 0028793725 scopus 로고
    • Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters
    • Sanglard, D., Kuchler, K., Ischer, F., Pagani, J. L., Monod, M., Bille, J.: Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters. Antimicrob Agents Chemother 39, 2378-2386 (1995).
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2378-2386
    • Sanglard, D.1    Kuchler, K.2    Ischer, F.3    Pagani, J.L.4    Monod, M.5    Bille, J.6
  • 93
    • 0030757227 scopus 로고    scopus 로고
    • Increased mRNA levels of ERG16, CDR and MDR1 correlate with increases in azole resistance in Candida albicans isolates from an HIV-infected patient
    • White, T. C.: Increased mRNA levels of ERG16, CDR and MDR1 correlate with increases in azole resistance in Candida albicans isolates from an HIV-infected patient. Antimicrob Agents Chemother 41, 1482-1487 (1997).
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1482-1487
    • White, T.C.1
  • 94
    • 0023653283 scopus 로고
    • Isolation of the Candida tropicalis gene for P450-lanosterol demethylase and its expression in Saccharomyces cerevisiae
    • Chen, C., Turi, T. G., Sanglard, D., Loper, J. C.: Isolation of the Candida tropicalis gene for P450-lanosterol demethylase and its expression in Saccharomyces cerevisiae. Biochem Biophys Res Commun 146, 1311-1317 (1987).
    • (1987) Biochem Biophys Res Commun , vol.146 , pp. 1311-1317
    • Chen, C.1    Turi, T.G.2    Sanglard, D.3    Loper, J.C.4
  • 95
    • 0027361467 scopus 로고
    • Resistance to imidazoles and triazoles in Saccharomyces cerevisiae as a new dominant marker
    • Doignon, F., Aigle, M., Ribereau, G. P.: Resistance to imidazoles and triazoles in Saccharomyces cerevisiae as a new dominant marker. Plasmid 30, 224-233 (1993).
    • (1993) Plasmid , vol.30 , pp. 224-233
    • Doignon, F.1    Aigle, M.2    Ribereau, G.P.3
  • 96
    • 0022981279 scopus 로고
    • Isolation of a cytochrome P450 structural gene from Saccharomyces cerevisiae
    • Kalb, V. F., Loper, J. C., Dey, C. R., Woods, C. W., Sutter, T. R.: Isolation of a cytochrome P450 structural gene from Saccharomyces cerevisiae. Gene 45, 237-245 (1986).
    • (1986) Gene , vol.45 , pp. 237-245
    • Kalb, V.F.1    Loper, J.C.2    Dey, C.R.3    Woods, C.W.4    Sutter, T.R.5
  • 97
    • 84907127080 scopus 로고
    • Genetic and physiological analysis of azole sensitivity in Saccharomyces cerevisiae
    • Kenna, S., Bligh, H. F., Watson, P. F., Kelly, S. L.: Genetic and physiological analysis of azole sensitivity in Saccharomyces cerevisiae. J Med Vet Mycol 27, 397-406 (1989).
    • (1989) J Med Vet Mycol , vol.27 , pp. 397-406
    • Kenna, S.1    Bligh, H.F.2    Watson, P.F.3    Kelly, S.L.4
  • 98
    • 0030792602 scopus 로고    scopus 로고
    • The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14α-demethylase in Candida albicans
    • White, T. C.: The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14α-demethylase in Candida albicans. Antimicrob Agents Chemother 41, 1488-1494 (1997).
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1488-1494
    • White, T.C.1
  • 100
    • 0028997579 scopus 로고
    • Colonizing populations of Candida albicans are clonal in origin but undergo micro-evolution through C-1 fragment reorganization as demonstrated by DNA fingerprinting and C-1 sequencing
    • Lockhart, S. R., Fritch, J. J., Meier, A. S., Schroppel, K., Srikantha, T., Galask, R., Soll, D. R.: Colonizing populations of Candida albicans are clonal in origin but undergo micro-evolution through C-1 fragment reorganization as demonstrated by DNA fingerprinting and C-1 sequencing. J Clin Microbiol 33, 1501-1509 (1995).
    • (1995) J Clin Microbiol , vol.33 , pp. 1501-1509
    • Lockhart, S.R.1    Fritch, J.J.2    Meier, A.S.3    Schroppel, K.4    Srikantha, T.5    Galask, R.6    Soll, D.R.7
  • 102
    • 0030893379 scopus 로고    scopus 로고
    • Characterization of Saccharomyces cerevisiae CYP61, sterol Δ(22)-desaturase and inhibition by azole antifungal agents
    • Kelly, S. L., Lamb, D. C., Baldwin, B. C., Corran, A. J., Kelly, D. E.: Characterization of Saccharomyces cerevisiae CYP61, sterol Δ(22)-desaturase and inhibition by azole antifungal agents. J Biol Chem 272, 9986-9988 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 9986-9988
    • Kelly, S.L.1    Lamb, D.C.2    Baldwin, B.C.3    Corran, A.J.4    Kelly, D.E.5
  • 103
    • 0028906887 scopus 로고
    • Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae - a review
    • Lees, N. D. Skaggs, B., Kirsch, D. R., Bard, M.: Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae - a review. Lipids 30, 221-226 (1995).
    • (1995) Lipids , vol.30 , pp. 221-226
    • Lees, N.D.1    Skaggs, B.2    Kirsch, D.R.3    Bard, M.4
  • 104
    • 0012991870 scopus 로고    scopus 로고
    • information. Web
    • Scherer, S., Ran, Y.: Candida albicans information. Web page. http://alces.med.umn.edu/Candida.html. (1996).
    • (1996) Candida albicans
    • Scherer, S.1    Ran, Y.2
  • 105
    • 0028302301 scopus 로고
    • Rapid detection and identification of Candida albicans and Torulopsis (Candida) glabrata in clinical specimens by species-specific nested PCR amplification of a cytochrome P450 lanosterolα - demethylase (L1A1) gene fragment
    • Burgener-Kairuz, P., Zuber, J. P., Jaunin, P., Buchman, T. G., Bille, J., Rossier, M.: Rapid detection and identification of Candida albicans and Torulopsis (Candida) glabrata in clinical specimens by species-specific nested PCR amplification of a cytochrome P450 lanosterolα - demethylase (L1A1) gene fragment. J Clin Microbiol 32, 1902-1907 (1994).
    • (1994) J Clin Microbiol , vol.32 , pp. 1902-1907
    • Burgener-Kairuz, P.1    Zuber, J.P.2    Jaunin, P.3    Buchman, T.G.4    Bille, J.5    Rossier, M.6
  • 106
    • 0028883458 scopus 로고
    • Deletion of the Candida glabrata ERG3 and ERG11 genes-effect on cell viability, cell growth, sterol composition, and antifungal susceptibility
    • Geber, A., Hitchcock, C. A., Swartz, J. E., Pullen, F. S., Marsden, K. E., Kwon-Chung, K. J., Bennett, J. E.: Deletion of the Candida glabrata ERG3 and ERG11 genes-effect on cell viability, cell growth, sterol composition, and antifungal susceptibility. Antimicrob Agents Chemother 39, 2708-2717 (1995).
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2708-2717
    • Geber, A.1    Hitchcock, C.A.2    Swartz, J.E.3    Pullen, F.S.4    Marsden, K.E.5    Kwon-Chung, K.J.6    Bennett, J.E.7
  • 107
    • 0023653283 scopus 로고
    • Isolation of the Candida tropicalis gene for P450 lanosterol demethylase and its expression in Saccharomyces cerevisiae
    • Chen, C., Turi, T. G., Sanglard, D., Loper, J. C.: Isolation of the Candida tropicalis gene for P450 lanosterol demethylase and its expression in Saccharomyces cerevisiae. Biochem Biophys Res Commun 146, 1311-1317 (1987).
    • (1987) Biochem Biophys Res Commun , vol.146 , pp. 1311-1317
    • Chen, C.1    Turi, T.G.2    Sanglard, D.3    Loper, J.C.4
  • 108
    • 0029818929 scopus 로고    scopus 로고
    • Resistance to fluconazole and amphotericin in Candida albicans from AIDS patients
    • Kelly, S. L., Larab, D. C., Kelly, D. E., Loeffler, J., Einsele, H.: Resistance to fluconazole and amphotericin in Candida albicans from AIDS patients. Lancet 348, 1523-1524 (1996).
    • (1996) Lancet , vol.348 , pp. 1523-1524
    • Kelly, S.L.1    Larab, D.C.2    Kelly, D.E.3    Loeffler, J.4    Einsele, H.5
  • 109
    • 0031024163 scopus 로고    scopus 로고
    • Resistance to fluconazole and crossresistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol Δ(5,6) desaturation
    • Kelly, S. L., Lam, D. C., Kelly, D. E., Manning, N. J., Loeffler, J., Hebart, H., Schumacher, U., Einsele, H.: Resistance to fluconazole and crossresistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol Δ(5,6) desaturation. FEBS Lett 400, 80-82 (1997).
    • (1997) FEBS Lett , vol.400 , pp. 80-82
    • Kelly, S.L.1    Lam, D.C.2    Kelly, D.E.3    Manning, N.J.4    Loeffler, J.5    Hebart, H.6    Schumacher, U.7    Einsele, H.8
  • 110
    • 0028985926 scopus 로고
    • Defective sterol Δ5(6) desaturase as a cause of azole resistance in Ustilago maydis
    • Joseph-Horne, T., Manning, N. J., Hollomon, D., Kelly S. L.: Defective sterol Δ5(6) desaturase as a cause of azole resistance in Ustilago maydis. FEMS Microbiol Lett 127, 29-34 (1995).
    • (1995) FEMS Microbiol Lett , vol.127 , pp. 29-34
    • Joseph-Horne, T.1    Manning, N.J.2    Hollomon, D.3    Kelly, S.L.4
  • 115
    • 0035019469 scopus 로고    scopus 로고
    • ABC transporters: Physiology, structure and mechanism - an overview
    • Higgins, C. F.: ABC transporters: Physiology, structure and mechanism - an overview. Res Microbiol 152 205-210 (2001).
    • (2001) Res Microbiol , vol.152 , pp. 205-210
    • Higgins, C.F.1
  • 116
    • 0028928549 scopus 로고
    • Molecular cloning and characterization of a novel gene of Candida albicans CDR1 conferring, multiple resistance to drugs and antifungals
    • Prasad, R., Worgifosse, P. D., Goffeau, A., Balzi, E.: Molecular cloning and characterization of a novel gene of Candida albicans CDR1 conferring, multiple resistance to drugs and antifungals. Curr Gent 27, 320-329 (1995).
    • (1995) Curr Gent , vol.27 , pp. 320-329
    • Prasad, R.1    Worgifosse, P.D.2    Goffeau, A.3    Balzi, E.4
  • 117
    • 0032487393 scopus 로고    scopus 로고
    • A fourth gene from the Candida albicans CDR family of ABC transporters
    • Franz, R., Michel, S., Morschhauser, J.: A fourth gene from the Candida albicans CDR family of ABC transporters. Gene 220, 91-98 (1998).
    • (1998) Gene , vol.220 , pp. 91-98
    • Franz, R.1    Michel, S.2    Morschhauser, J.3
  • 118
    • 34548418697 scopus 로고    scopus 로고
    • Cannon, R. D., Tsao, S., Ong, S., Niimi, K., Lamping, E., Monk, B. C., Holmes, A. R.: Allelic variation affecting drug pump function in Candida albicans. ASM conference on Candida and Candidiasis abstract no. 147(C). March 18-22 (2004) Austin, TX.
    • Cannon, R. D., Tsao, S., Ong, S., Niimi, K., Lamping, E., Monk, B. C., Holmes, A. R.: Allelic variation affecting drug pump function in Candida albicans. ASM conference on Candida and Candidiasis abstract no. 147(C). March 18-22 (2004) Austin, TX.
  • 119
    • 1442277718 scopus 로고    scopus 로고
    • The role of MDR1 genetic polymorphisms in individual variability in P-glycoprotein expression and function
    • Woodahl, E. L., Ho, R. J.: The role of MDR1 genetic polymorphisms in individual variability in P-glycoprotein expression and function. Curr Drug Metab 5, 11-19 (2004).
    • (2004) Curr Drug Metab , vol.5 , pp. 11-19
    • Woodahl, E.L.1    Ho, R.J.2
  • 120
    • 0037195962 scopus 로고    scopus 로고
    • Candida giabarata ATP-binding cassette transporter, Cdr1p and Pdh1p expressed in a Saccharomyces cerevisiae strain deficient in membrane transporter show phosphorylation dependent pumping properties
    • Wada, S., Niimi, M., Niimi, K., Holmes, A. R., Monk, B. C., Cannon, R. D., Uehara, Y.: Candida giabarata ATP-binding cassette transporter, Cdr1p and Pdh1p expressed in a Saccharomyces cerevisiae strain deficient in membrane transporter show phosphorylation dependent pumping properties. J Biol Chem 272, 46809-46821 (2002).
    • (2002) J Biol Chem , vol.272 , pp. 46809-46821
    • Wada, S.1    Niimi, M.2    Niimi, K.3    Holmes, A.R.4    Monk, B.C.5    Cannon, R.D.6    Uehara, Y.7
  • 121
    • 4744358624 scopus 로고    scopus 로고
    • The ATP switch model for ABC transporters
    • Higgins, C. F., Linton, K. J.: The ATP switch model for ABC transporters. Nat Struct Mol Biol 11, 918-926 (2004).
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 918-926
    • Higgins, C.F.1    Linton, K.J.2
  • 122
    • 0001607723 scopus 로고
    • Distantly related sequences in the α-and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
    • Walker, J. E., Sarsate, M., Runswick, M., Gay, N. L: Distantly related sequences in the α-and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J 1, 945-951 (1982).
    • (1982) EMBO J , vol.1 , pp. 945-951
    • Walker, J.E.1    Sarsate, M.2    Runswick, M.3    Gay, N.L.4
  • 123
    • 0031810816 scopus 로고    scopus 로고
    • ATP-binding-cassette (ABC) transport systems: Functional and structural aspects of the ATP-hydrolyzing subunits/ domains
    • Schneider, E., Hunke, S.: ATP-binding-cassette (ABC) transport systems: Functional and structural aspects of the ATP-hydrolyzing subunits/ domains FEMS. Microbiol Rev 22, 1-20 (1998).
    • (1998) FEMS. Microbiol Rev , vol.22 , pp. 1-20
    • Schneider, E.1    Hunke, S.2
  • 124
    • 0042318833 scopus 로고    scopus 로고
    • Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: Uncommon cysteine 193 of Walker A is critical for ATP hydrolysis
    • Jha, S., Karnani, N., Dhar, S. K., Mukhopadhyay, K., Shukla S., Saini, P., Mukhopadhyay, G., Prasad, R.: Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis. Biochem 42, 10822-10832 (2003).
    • (2003) Biochem , vol.42 , pp. 10822-10832
    • Jha, S.1    Karnani, N.2    Dhar, S.K.3    Mukhopadhyay, K.4    Shukla, S.5    Saini, P.6    Mukhopadhyay, G.7    Prasad, R.8
  • 125
    • 0037449746 scopus 로고    scopus 로고
    • Drug binding in human p-glycoprotein causes conformational changes in both nucleotide-binding domains
    • Loo, T. W., Bartlett, M. C., Clarke, D. M.: Drug binding in human p-glycoprotein causes conformational changes in both nucleotide-binding domains. J Biol Chem 278, 1575-1578 (2003).
    • (2003) J Biol Chem , vol.278 , pp. 1575-1578
    • Loo, T.W.1    Bartlett, M.C.2    Clarke, D.M.3
  • 126
    • 0036177187 scopus 로고    scopus 로고
    • Transcription initiation of genes associated with resistance in Candida albicans
    • Harry, J. B., Song, J. L., Lyons, C. N., White, T. C.: Transcription initiation of genes associated with resistance in Candida albicans. Med Mycol 40, 73-81 (2003).
    • (2003) Med Mycol , vol.40 , pp. 73-81
    • Harry, J.B.1    Song, J.L.2    Lyons, C.N.3    White, T.C.4
  • 127
    • 0032580522 scopus 로고    scopus 로고
    • Deletion of transmembrane domain 12 of CDR1, a multidrug transporter from Candida albicans, leads to altered drug specificity: Expression of a yeast multidrug transporter n baculovirus expression system
    • Krishnamurthy, S., Chatterjee, U., Gupta, V., Prasad, R., Das, P., Snehlata, P., Hasnain, S. E., Prasad, R.: Deletion of transmembrane domain 12 of CDR1, a multidrug transporter from Candida albicans, leads to altered drug specificity: expression of a yeast multidrug transporter n baculovirus expression system. Yeast 14, 535-550 (1998).
    • (1998) Yeast , vol.14 , pp. 535-550
    • Krishnamurthy, S.1    Chatterjee, U.2    Gupta, V.3    Prasad, R.4    Das, P.5    Snehlata, P.6    Hasnain, S.E.7    Prasad, R.8
  • 128
    • 0028982951 scopus 로고
    • Functional dissection of P-glycoprotein nucleotide-binding domains in chimeric and mutant proteins. Modulation of drug resistance profiles
    • Beaudet, L. Gros, P.: Functional dissection of P-glycoprotein nucleotide-binding domains in chimeric and mutant proteins. Modulation of drug resistance profiles. J Biol Chem 270, 17159-17170 (1995).
    • (1995) J Biol Chem , vol.270 , pp. 17159-17170
    • Beaudet, L.1    Gros, P.2
  • 129
    • 17844379452 scopus 로고    scopus 로고
    • Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: Uncommon but conserved Trp326 of Walker B is important for ATP binding
    • Rai, V., Shukla, S., Jha, S., Komath, S. S., Prasad, R.: Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: Uncommon but conserved Trp326 of Walker B is important for ATP binding. Bichemistry 44, 6650-6661 (2005).
    • (2005) Bichemistry , vol.44 , pp. 6650-6661
    • Rai, V.1    Shukla, S.2    Jha, S.3    Komath, S.S.4    Prasad, R.5
  • 130
    • 0030795417 scopus 로고    scopus 로고
    • Tryptophan fluorescence reports nucleotide-induced conformational changes in a domain of the ArsA ATPase
    • Zhou, T., Rosen, B. P.: Tryptophan fluorescence reports nucleotide-induced conformational changes in a domain of the ArsA ATPase. J Biol Chem 272, 19731-19737 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 19731-19737
    • Zhou, T.1    Rosen, B.P.2
  • 131
    • 0028293750 scopus 로고
    • Candida albicans gene encoding resistance to benomyl and methotrexate is a multidrug resistance gene
    • Ben-Yaacov, R., Knoller, S., Caldwell, G. A., Becker, J. M., Koltin, Y.: Candida albicans gene encoding resistance to benomyl and methotrexate is a multidrug resistance gene. Antimicrob Agents Chemother 38, 648-652 (1994).
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 648-652
    • Ben-Yaacov, R.1    Knoller, S.2    Caldwell, G.A.3    Becker, J.M.4    Koltin, Y.5
  • 132
    • 0025774660 scopus 로고
    • Analysis of a Candida albicans gene that encodes a novel mechanism for resistance to benomyl and methotrexate
    • Fling, M. E., Kopf, J., Tamarkin, A., Gorman, J. A., Smith, H. A., Koltin, Y.: Analysis of a Candida albicans gene that encodes a novel mechanism for resistance to benomyl and methotrexate. Mol Gen Genet 227, 318-329 (1991).
    • (1991) Mol Gen Genet , vol.227 , pp. 318-329
    • Fling, M.E.1    Kopf, J.2    Tamarkin, A.3    Gorman, J.A.4    Smith, H.A.5    Koltin, Y.6
  • 133
    • 0028844181 scopus 로고
    • Reduced virulence of Candida albicans mutants affected in multidrug resistance
    • Becker, J. M., Henry, L. K., Jiang, W., Koltin, Y.: Reduced virulence of Candida albicans mutants affected in multidrug resistance. Infec Immun 63, 4515-4518 (1995).
    • (1995) Infec Immun , vol.63 , pp. 4515-4518
    • Becker, J.M.1    Henry, L.K.2    Jiang, W.3    Koltin, Y.4
  • 134
    • 0031692037 scopus 로고    scopus 로고
    • Identification of seven mutant alleles of CaMDR1, a membrane facilitator of Candida albicans which confers multidrug resistance and its in vitro transcriptional activation
    • Gupta, V., Kohli, A. K., Krishnamurthy, S., Puri, N., Aalamgeer, S. A., Panwar, S. L., Prasad, R.: Identification of seven mutant alleles of CaMDR1, a membrane facilitator of Candida albicans which confers multidrug resistance and its in vitro transcriptional activation. Curr Genet 34, 192-199 (1998).
    • (1998) Curr Genet , vol.34 , pp. 192-199
    • Gupta, V.1    Kohli, A.K.2    Krishnamurthy, S.3    Puri, N.4    Aalamgeer, S.A.5    Panwar, S.L.6    Prasad, R.7
  • 136
    • 0033969525 scopus 로고    scopus 로고
    • Analysis of tangled relationships between P-glycoprotein mediated multidrug resistant and the lipid phase of the cell membrane
    • Ferte, J.: Analysis of tangled relationships between P-glycoprotein mediated multidrug resistant and the lipid phase of the cell membrane. Eur J Biochem 267, 277-294 (2000).
    • (2000) Eur J Biochem , vol.267 , pp. 277-294
    • Ferte, J.1
  • 137
    • 0036894215 scopus 로고    scopus 로고
    • Drug susceptibilities of yeast cells are affected by membrane lipid composition
    • Mukhopadhyay, K., Kohli, A. K., Prasad, R.: Drug susceptibilities of yeast cells are affected by membrane lipid composition. Antimicrob Agents Chemother 46, 3695-3705 (2002).
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3695-3705
    • Mukhopadhyay, K.1    Kohli, A.K.2    Prasad, R.3
  • 138
    • 0000942202 scopus 로고    scopus 로고
    • PDR16 and PDR17, two homologous genes of Sacchromyces cereviside affect lipid biosyntheis and resistance to multiple drugs
    • Van Den Hazel, H. B., Pichler, H., Do Valle Matta, M. A., Leitner, E., Goffeau, A., Daum, G.: PDR16 and PDR17, two homologous genes of Sacchromyces cereviside affect lipid biosyntheis and resistance to multiple drugs. J Biol Chem 274, 1934-1941 (1999).
    • (1999) J Biol Chem , vol.274 , pp. 1934-1941
    • Van Den Hazel, H.B.1    Pichler, H.2    Do Valle Matta, M.A.3    Leitner, E.4    Goffeau, A.5    Daum, G.6
  • 139
    • 0028814142 scopus 로고
    • Isolation of fluconazole-resistant Candida albicans from human immunodeficiency virus negative patients never treated with azoles
    • Goff, D. A., Koletar S. L., Buesching, W. J., Barnishan, J., Fass, R. J.: Isolation of fluconazole-resistant Candida albicans from human immunodeficiency virus negative patients never treated with azoles. Clin Infect Dis 20, 77-83 (1995).
    • (1995) Clin Infect Dis , vol.20 , pp. 77-83
    • Goff, D.A.1    Koletar, S.L.2    Buesching, W.J.3    Barnishan, J.4    Fass, R.J.5
  • 140
    • 0028887667 scopus 로고
    • Invasive infection due to Candida krusei in immunocompromised patients not treated with fluconazole
    • Iwen, P. C., Kelly, D. M., Reed, E. C., Hinrichs, S. H.: Invasive infection due to Candida krusei in immunocompromised patients not treated with fluconazole. Clin Infect Dis 20, 342-347 (1995).
    • (1995) Clin Infect Dis , vol.20 , pp. 342-347
    • Iwen, P.C.1    Kelly, D.M.2    Reed, E.C.3    Hinrichs, S.H.4
  • 141
    • 0026093688 scopus 로고
    • Increase in Candida krusei infection among patients with bone marrow transplantation and neutropenia treated prophylactically with fluconazole
    • Wingard, J. R., Merz, W. G., Rinaldi, M.G., Jonhson, T. R., Karp, J. E., Saral, R.: Increase in Candida krusei infection among patients with bone marrow transplantation and neutropenia treated prophylactically with fluconazole. N Engl J Med 325, 1274-1277 (1991).
    • (1991) N Engl J Med , vol.325 , pp. 1274-1277
    • Wingard, J.R.1    Merz, W.G.2    Rinaldi, M.G.3    Jonhson, T.R.4    Karp, J.E.5    Saral, R.6
  • 142
    • 0345340404 scopus 로고    scopus 로고
    • The changing face of candidemia: Emergence of non-Candida albicans species and antifungal resistance
    • Nguyen, M. H., Peacock, J. E., Morris, A. J.: The changing face of candidemia: emergence of non-Candida albicans species and antifungal resistance. Am J Med 100, 617-623 (1996).
    • (1996) Am J Med , vol.100 , pp. 617-623
    • Nguyen, M.H.1    Peacock, J.E.2    Morris, A.J.3
  • 143
    • 0031157777 scopus 로고    scopus 로고
    • The epidemiology of hematogeneous candidiasis caused by different Candida species
    • Abi Said, D., Anaissie, E., Uzun, O., Pinzcowski, H., Vartivarian, S.: The epidemiology of hematogeneous candidiasis caused by different Candida species. Clin Infect Dis 24, 1122-1128 (1997).
    • (1997) Clin Infect Dis , vol.24 , pp. 1122-1128
    • Abi Said, D.1    Anaissie, E.2    Uzun, O.3    Pinzcowski, H.4    Vartivarian, S.5
  • 144
    • 0034715262 scopus 로고    scopus 로고
    • Candida krusei fungemia: An escalating serious infection in immunocompromised patients
    • Abbas, J., Bodey, G. P., Hanna, H. A. et al.: Candida krusei fungemia: An escalating serious infection in immunocompromised patients. Arch Intern Med 160, 2659-2664 (2000).
    • (2000) Arch Intern Med , vol.160 , pp. 2659-2664
    • Abbas, J.1    Bodey, G.P.2    Hanna, H.A.3
  • 145
    • 0032815877 scopus 로고    scopus 로고
    • Candida glabrata fungemia: Clinical features of 139 patients
    • Gumbo, T., Isada, C. M., Hall, G., Karafa, M. T., Gordon, S. M.: Candida glabrata fungemia: Clinical features of 139 patients. Medicine (Balt) 78, 220-227 (1999).
    • (1999) Medicine (Balt) , vol.78 , pp. 220-227
    • Gumbo, T.1    Isada, C.M.2    Hall, G.3    Karafa, M.T.4    Gordon, S.M.5
  • 146
    • 0032953377 scopus 로고    scopus 로고
    • Candidemia in cancer patients: A prospective, multicenter surveillance study by the Invasive Fungal Infection Group (IFIG) of the European Organization for Research and Treatment of Cancer (EORTC)
    • Viscoli, C., Girmenia, C., Marinus, A. et al.: Candidemia in cancer patients: a prospective, multicenter surveillance study by the Invasive Fungal Infection Group (IFIG) of the European Organization for Research and Treatment of Cancer (EORTC). Clin Infect Dis 28, 1071-1079 (1999).
    • (1999) Clin Infect Dis , vol.28 , pp. 1071-1079
    • Viscoli, C.1    Girmenia, C.2    Marinus, A.3
  • 147
    • 0034128718 scopus 로고    scopus 로고
    • The spectrum of Fusarium infection in immunocompromised patients with haematological malignancies and in non-immuno-compromised patients: A single institution experience over 10 years
    • Musa, M. O., Eisa, A. A., Halim, M. et al.: The spectrum of Fusarium infection in immunocompromised patients with haematological malignancies and in non-immuno-compromised patients: a single institution experience over 10 years. Br J Haematol 108, 544-548 (2000).
    • (2000) Br J Haematol , vol.108 , pp. 544-548
    • Musa, M.O.1    Eisa, A.A.2    Halim, M.3
  • 148
    • 0033764059 scopus 로고    scopus 로고
    • The epidemiology of fusariosis in patients with haematological diseases. Gimema Infection Programme
    • Girmenia, C., Pagano, L., Corvatta, L., Mele, L., del Favero, A., Martino, P.: The epidemiology of fusariosis in patients with haematological diseases. Gimema Infection Programme. Br J Haematol 111, 272-276 (2000).
    • (2000) Br J Haematol , vol.111 , pp. 272-276
    • Girmenia, C.1    Pagano, L.2    Corvatta, L.3    Mele, L.4    del Favero, A.5    Martino, P.6
  • 149
    • 0030797578 scopus 로고    scopus 로고
    • Deep infections caused by Scedosporium prolificans. A report on 16 cases in Spain and a review of the literature. Scedosporium prolificans Spanish Study Group
    • Berenguer, J., Rodriguez-Tudela, J. L., Richard, C. et al.: Deep infections caused by Scedosporium prolificans. A report on 16 cases in Spain and a review of the literature. Scedosporium prolificans Spanish Study Group. Medicine (Balt) 76, 256-265 (1997).
    • (1997) Medicine (Balt) , vol.76 , pp. 256-265
    • Berenguer, J.1    Rodriguez-Tudela, J.L.2    Richard, C.3
  • 150
    • 0026530146 scopus 로고
    • Clinical features of human infection with Scedosporium inflatum
    • Wood, G. M., McCormack, J. G., Muir, D. B. et al.: Clinical features of human infection with Scedosporium inflatum. Clin Infect Dis 14, 1027-1033 (1992).
    • (1992) Clin Infect Dis , vol.14 , pp. 1027-1033
    • Wood, G.M.1    McCormack, J.G.2    Muir, D.B.3
  • 151
    • 0031901306 scopus 로고    scopus 로고
    • Invasive pulmonary aspergillosis due to Aspergillus terreus: 12-year experience and review of the literature
    • Iwen, C., Rupp, M. E., Langnas, A. N., Reed, E. C., Hinrichs, S. H.: Invasive pulmonary aspergillosis due to Aspergillus terreus: 12-year experience and review of the literature. Clin Infect Dis 26, 1092-1097 (1998).
    • (1998) Clin Infect Dis , vol.26 , pp. 1092-1097
    • Iwen, C.1    Rupp, M.E.2    Langnas, A.N.3    Reed, E.C.4    Hinrichs, S.H.5
  • 152
    • 0036724743 scopus 로고    scopus 로고
    • Antifungal drug resistance to azoles and polyenes
    • Canuto, M. M., Rodero, F. G.: Antifungal drug resistance to azoles and polyenes. Lancet Infectious Disease 2, 550-563 (2002).
    • (2002) Lancet Infectious Disease , vol.2 , pp. 550-563
    • Canuto, M.M.1    Rodero, F.G.2
  • 154
    • 0033796346 scopus 로고    scopus 로고
    • Practice guidelines for the treatment of candidiasis
    • Rex, J. H., Walsh, T. J., Sobel, J. D. et al.: Practice guidelines for the treatment of candidiasis. Clin Infect Dis 30, 662-678 (2000).
    • (2000) Clin Infect Dis , vol.30 , pp. 662-678
    • Rex, J.H.1    Walsh, T.J.2    Sobel, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.