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Volumn 149, Issue 1, 1997, Pages 25-30

Differential inhibition of Candida albicans CYP51 with azole antifungal stereoisomers

Author keywords

Azole antifungal; P450; Stereoselective inhibition

Indexed keywords

GENACONAZOLE; PYRROLE; TETRACONAZOLE; UNCLASSIFIED DRUG;

EID: 0030894125     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(97)00049-9     Document Type: Article
Times cited : (36)

References (11)
  • 1
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    • Molecular studies on azole sensitivity in fungi
    • (Maresca, B., Kobayashi, G.S. and Yamaguchi, H., Eds.), Springer-Verlag, Berlin
    • Kelly, S.L. and Kelly, D.E. (1993) Molecular studies on azole sensitivity in fungi. In : Molecular Biology and Applications to Medical Mycology (Maresca, B., Kobayashi, G.S. and Yamaguchi, H., Eds.), pp. 199-213. Springer-Verlag, Berlin.
    • (1993) Molecular Biology and Applications to Medical Mycology , pp. 199-213
    • Kelly, S.L.1    Kelly, D.E.2
  • 2
    • 0028942449 scopus 로고
    • Mode of action and resistance to azole antifungals associated with the formation of 14α-methylergosta-8,24(28)-dien-3β,6α-diol
    • Kelly, S.L., Lamb, D.C., Corran, A.C., Baldwin, B.C. and Kelly, D.E. (1995) Mode of action and resistance to azole antifungals associated with the formation of 14α-methylergosta-8,24(28)-dien-3β,6α-diol. Biochem. Biophys. Res. Commun. 207, 910-915.
    • (1995) Biochem. Biophys. Res. Commun. , vol.207 , pp. 910-915
    • Kelly, S.L.1    Lamb, D.C.2    Corran, A.C.3    Baldwin, B.C.4    Kelly, D.E.5
  • 4
    • 0027741012 scopus 로고
    • Resistance to azole fungicides in the field
    • Hollomon, D. (1993) Resistance to azole fungicides in the field. Biochem. Soc. Trans. 21, 1047-1051.
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 1047-1051
    • Hollomon, D.1
  • 6
    • 0029146207 scopus 로고
    • Resistance to fluconazole in Candida albicans from AIDS patients correlated with reduced intracellular accumulation of drug
    • Venkateswarlu, K., Denning, D.W., Manning, N.J. and Kelly, S.L. (1995) Resistance to fluconazole in Candida albicans from AIDS patients correlated with reduced intracellular accumulation of drug. FEMS Microbiol. Lett. 131, 337-341.
    • (1995) FEMS Microbiol. Lett. , vol.131 , pp. 337-341
    • Venkateswarlu, K.1    Denning, D.W.2    Manning, N.J.3    Kelly, S.L.4
  • 8
    • 0014559258 scopus 로고
    • Ligand interactions with cytochrome P450. I. Binding of primary amines
    • Jefcoate, C.R., Gaylor, J.L. and Calabrese, R.L. (1969) Ligand interactions with cytochrome P450. I. Binding of primary amines. Biochemistry 8, 3455-3463.
    • (1969) Biochemistry , vol.8 , pp. 3455-3463
    • Jefcoate, C.R.1    Gaylor, J.L.2    Calabrese, R.L.3
  • 9
    • 0029974620 scopus 로고    scopus 로고
    • The ubiquitously expressed human CYP51 encodes lanosterol 14α-demethylase, a cytochrome P450 whose expression is regulated by oxysterols
    • Stromstedt, M., Rozman, D. and Waterman, M.R. (1996) The ubiquitously expressed human CYP51 encodes lanosterol 14α-demethylase, a cytochrome P450 whose expression is regulated by oxysterols. Arch. Biochem. Biophys. 329, 73-81.
    • (1996) Arch. Biochem. Biophys. , vol.329 , pp. 73-81
    • Stromstedt, M.1    Rozman, D.2    Waterman, M.R.3
  • 10
    • 0029125246 scopus 로고
    • P450 inhibitors of use in medical treatment; Focus on mechanism of action
    • Vanden Bossche, H., Koymans, L., Moreels, H. (1995) P450 inhibitors of use in medical treatment; Focus on mechanism of action. Pharmacol. Ther. 67, 97-100.
    • (1995) Pharmacol. Ther. , vol.67 , pp. 97-100
    • Vanden Bossche, H.1    Koymans, L.2    Moreels, H.3
  • 11
    • 0028807725 scopus 로고
    • Altered P450 activity associated with direct selection for fungal azole resistance
    • Joseph-Home, T., Hollomon, D., Loeffler, R.S.T. and Kelly, S.L. (1995) Altered P450 activity associated with direct selection for fungal azole resistance. FEBS Lett. 374, 174-178.
    • (1995) FEBS Lett. , vol.374 , pp. 174-178
    • Joseph-Home, T.1    Hollomon, D.2    Loeffler, R.S.T.3    Kelly, S.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.