Cloning and characterization of ERG25, the Saccharomyces cerevisiae gene encoding C-4 sterol methyl oxidase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 1, 1996, Pages 186-190

  Bard, M ^a   Bruner, D A ^a   Pierson, C A ^a   Lees, N D ^a   Biermann, B ^a   Frye, L ^b   Koegel, C ^c   Barbuch, R ^c  

^a INDIANA UNIVERSITY   (United States)

^b RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^c Marion Merrell Dow Pharmaceuticals   (United States)

Author keywords

fungi; sterol biosynthesis

Indexed keywords

CHOLESTEROL; ERGOSTEROL; STEROL; STIGMASTEROL;

AMINO ACID SEQUENCE; ARTICLE; AUXOTROPHY; CARBOXY TERMINAL SEQUENCE; CHOLESTEROL SYNTHESIS; DEMETHYLATION; DNA SEQUENCE; ENDOPLASMIC RETICULUM; GENETIC ANALYSIS; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS; STEROL SYNTHESIS;

AMINO ACID SEQUENCE; BASE SEQUENCE; CLONING, MOLECULAR; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENES, FUNGAL; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; RESTRICTION MAPPING; SACCHAROMYCES CEREVISIAE;

ANIMALIA; BACTERIA (MICROORGANISMS); EUKARYOTA; FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0030033387     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.1.186     Document Type: Article

References (22)

1. Miller, W. L., Kalafer, M. E., Gaylor, J. L. & Delwicke, C. V. (1967) Biochemistry 6, 2673-2678.
2. Williams, M. T., Gaylor, J. L. & Morris, H. R. (1977) Cancer Res. 37, 1377-1383.
3. Faust, J. L., Trzaskos, J. M. & Gaylor, J. M. (1988) in Biology of Cholesterol, ed. Yeagle, P. L. (CRC, Boca Raton, FL), pp. 19-38.
4. Maitra, U. S., Mohan, V. P., Kochi, H., Shankar, V., Adlersberg, M., Liu, K.-P., Ponticorvo, L. & Sprinson, D. B. (1982) Biochem. Biophys. Res. Commun. 108, 517-525.
5. Fukushima, H., Grinstead, G. F. & Gaylor, J. L. (1981) J. Biol. Chem. 256, 4822-4826.
6. Lees, N. D., Skaggs, B., Kirsch, D. R. & Bard, M. (1995) Lipids 30, 221-226.
7. Plemenitas, A., Havel, C. M. & Watson, J. A. (1990) J. Biol. Chem. 265, 17012-17017.
8. Vanden Bossche, H., Marichal, P., LeJune, L., Coene, M.-C., Gorrens, J. & Cools, W. (1993) Antimicrob. Agents Chemother. 37, 2101-2105.
9. Lewis, T. L., Keesler, G. A., Fenner, G. P. & Parks, L. W. (1988) Yeast 4, 93-106.
10. Sherman, F., Fink, G. R. & Hicks, J. (1986) Methods in Yeast Genetics (Cold Spring Harbor Lab. Press, Plainview, NY).
11. Rose, M. D., Novick, P., Thomas, J. H., Holstein, D. & Fink, G. R. (1987) Gene 60, 237-243.
12. Maniatis, T., Fritsch, E. F. & Sambrook, J. (1982) Molecular Cloning (Cold Spring Harbor Lab. Press, Plainview, NY).
13. Sikorski, R. S. & Hieter, P. (1989) Genetics 122, 19-27.
14. Rothstein, F. J. (1983) Methods Enzymol. 101, 202-211.
15. Molzahn, S. W. & Woods, R. A. (1972) J. Gen. Microbiol. 72, 339-348.
16. Kuchta, T., Bartkova, K. & Kubinec, R. (1992) Biochem. Biophys. Res. Commun. 189, 85-91.
17. Maitra, U., Mohan, V. P. & Sprinson, D. B. (1989) Steroids 53, 597-605.
18. Byskov, A. G., Andersen, C. Y., Nordholm, L., Thogersen, H., Guoliang, X., Wasserman, O., Andersen, J. V., Guddal, E. & Roed, T. (1995) Nature (London) 374, 559-562.
19. Kyte, J. & Doolittle, R. F. (1982) J. Mol. Biol. 157, 105-132.
20. Arthington, B. A., Bennett, L. G., Skatrud, P. L., Guynn, C. J., Barbuch, R. J., Ulbright, C. E. & Bard, M. (1991) Gene 102, 39-44.
21. Shin, J., Dunbrack, R. L., Lee, S. & Strominger, J. L. (1991) Proc. Natl. Acad. Sci. USA 88, 1918-1922.
22. Shanklin, J., Whittle, E. & Fox, B. G. (1994) Biochemistry 33, 12787-12794.