Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: Uncommon but conserved Trp326 of walker B is important for ATP binding

Biochemistry

Volumn 44, Issue 17, 2005, Pages 6650-6661

  Rai, Versha ^a   Shukla, Sudhanshu ^a   Jha, Sudhakar ^a   Komath, Sneha Sudha ^a   Prasad, Rajendra ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; EXTRUSION; FLUORESCENCE; FUNGI; HYDROLYSIS; SPECTROSCOPIC ANALYSIS; YEAST;

BINDING DOMAINS; HUMAN PATHOGENIC YEASTS; MULTIDRAG EXTRUSION PUMPS; NUCLEOTIDE BINDING;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATE;

AMINO TERMINAL SEQUENCE; ARTICLE; CANDIDA ALBICANS; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; FLUORESCENCE SPECTROSCOPY; GENE MUTATION; HYDROLYSIS; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ADENOSINE TRIPHOSPHATE; ALANINE; AMINO ACID MOTIFS; ATP-BINDING CASSETTE TRANSPORTERS; BINDING SITES; BROMOSUCCINIMIDE; CANDIDA ALBICANS; CONSERVED SEQUENCE; DRUG RESISTANCE, FUNGAL; FLUORESCENT DYES; FUNGAL PROTEINS; MAGNESIUM; MEMBRANE TRANSPORT PROTEINS; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SPECTROPHOTOMETRY; TRYPTOPHAN;

CANDIDA ALBICANS;

EID: 17844379452     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0474160     Document Type: Article

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