Investigation of α-synuclein fibril structure by site-directed spin labeling

Journal of Biological Chemistry

Volumn 282, Issue 34, 2007, Pages 24970-24979

  Chen, Min ^a,b   Margittai, Martin ^b   Chen, Jeannie ^a,b   Langen, Ralf ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; DISEASES; ELECTRON SPIN RESONANCE SPECTROSCOPY;

AMYLOID FIBRILS; FIBRIL FORMATION; ORBITAL OVERLAP; SPIN LABELING;

PROTEINS;

ALPHA SYNUCLEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; HUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; SPIN LABELING;

ALPHA-SYNUCLEIN; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MUTATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SPIN LABELS;

EID: 34548359337     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700368200     Document Type: Article

References (70)

1. Iwai, A., Masliah, E., Yoshimoto, M., Ge, N., Flanagan, L., de Silva, H. A., Kittel, A., and Saitoh, T. (1995) Neuron 14, 467-475
2. Maroteaux, L., Campanelli, J. T., and Scheller, R. H. (1988) J. Neurosci. 8, 2804-2815
3. Soto, C. (2003) Nat. Rev. Neurosci. 4, 49-60
4. Goedert, M. (2001) Nat. Rev. Neurosci. 2, 492-501
5. Norris, E. H., Giasson, B. I., and Lee, V. M. (2004) Curr. Top Dev. Biol. 60, 17-54
6. Ueda, K., Fukushima, H., Masliah, E., Xia, Y., Iwai, A., Yoshimoto, M., Otero, D. A., Kondo, J., Ihara, Y., and Saitoh, T. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 11282-11286
7. Giasson, B. I., Jakes, R., Goedert, M., Duda, J. E., Leight, S., Trojanowski, J. Q., and Lee, V. M. (2000) J. Neurosci. Res. 59, 528-533
8. Jellinger, K. A. (2003) Acta Neuropathol. (Berl.) 106, 191-201
9. Duda, J. E., Giasson, B. I., Gur, T. L., Montine, T. J., Robertson, D., Biaggioni, I., Hurtig, H. I., Stern, M. B., Gollomp, S. M., Grossman, M., Lee, V. M., and Trojanowski, J. Q. (2000) J. Neuropathol. Exp. Neurol. 59, 830-841
10. Polymeropoulos, M. H., Lavedan, C., Leroy, E., Ide, S. E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., Stenroos, E. S., Chandrasekharappa, S., Athanassiadou, A., Papapetropoulos, T., Johnson, W. G., Lazzarini, A. M., Duvoisin, R. C., Di Iorio, G., Golbe, L. I., and Nussbaum, R. L. (1997) Science 276, 2045-2047
11. Kruger, R., Kuhn, W., Muller, T., Woitalla, D., Graeber, M., Kosel, S., Przuntek, H., Epplen, J. T., Schols, L., and Riess, O. (1998) Nat. Genet. 18, 106-108
12. Zarranz, J. J., Alegre, J., Gomez-Esteban, J. C., Lezcano, E., Ros, R., Ampuero, I., Vidal, L., Hoenicka, J., Rodriguez, O., Atares, B., Llorens, V., Gomez Tortosa, E., del Ser, T., Munoz, D. G., and de Yebenes, J. G. (2004) Ann. Neurol. 55, 164-173
13. Chartier-Harlin, M. C., Kachergus, J., Roumier, C., Mouroux, V., Douay, X., Lincoln, S., Levecque, C., Larvor, L., Andrieux, J., Hulihan, M., Waucquier, N., Defebvre, L., Amouyel, P., Farrer, M., and Destee, A. (2004) Lancet 364, 1167-1169
14. Ibanez, P., Bonnet, A. M., Debarges, B., Lohmann, E., Tison, F., Pollak, P., Agid, Y., Durr, A., and Brice, A. (2004) Lancet 364, 1169-1171
15. Singleton, A. B., Farrer, M., Johnson, J., Singleton, A., Hague, S., Kachergus, J., Hulihan, M., Peuralinna, T., Dutra, A., Nussbaum, R., Lincoln, S., Crawley, A., Hanson, M., Maraganore, D., Adler, C., Cookson, M. R., Muenter, M., Baptista, M., Miller, D., Blancato, J., Hardy, J., and Gwinn-Hardy, K. (2003) Science 302, 841
16. Feany, M. B., and Bender, W. W. (2000) Nature 404, 394-398
17. Masliah, E., Rockenstein, E., Veinbergs, I., Mallory, M., Hashimoto, M., Takeda, A., Sagara, Y., Sisk, A., and Mucke, L. (2000) Science 287, 1265-1269
18. Lee, M. K., Stirling, W., Xu, Y., Xu, X., Qui, D., Mandir, A. S., Dawson, T. M., Copeland, N. G., Jenkins, N. A., and Price, D. L. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 8968-8973
19. Kirik, D., Rosenblad, C., Burger, C., Lundberg, C., Johansen, T. E., Muzyczka, N., Mandel, R. J., and Bjorklund, A. (2002) J. Neurosci. 22, 2780-2791
20. Smith, D., Trennery, P., Farningham, D., and Klapwijk, J. (2001) Lab. Anim. 35, 117-130
21. Kirik, D., Annett, L. E., Burger, C., Muzyczka, N., Mandel, R. J., and Bjorklund, A. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 2884-2889
22. Caughey, B., and Lansbury, P. T. (2003) Annu. Rev. Neurosci. 26, 267-298
23. Serpell, L. C., Berriman, J., Jakes, R., Goedert, M., and Crowther, R. A. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 4897-4902
24. Der-Sarkissian, A., Jao, C. C., Chen, J., and Langen, R. (2003) J. Biol. Chem. 278, 37530-37535
25. Del Mar, C., Greenbaum, E. A., Mayne, L., Englander, S. W., and Woods, V. L., Jr. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 15477-15482
26. Heise, H., Hoyer, W., Becker, S., Andronesi, O. C., Riedel, D., and Baldus, M. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 15871-15876
27. Miake, H., Mizusawa, H., Iwatsubo, T., and Hasegawa, M. (2002) J. Biol. Chem. 277, 19213-19219
28. Hubbell, W. L., Gross, A., Langen, R., and Lietzow, M. A. (1998) Curr. Opin. Struct. Biol. 8, 649-656
29. Margittai, M., and Langen, R. (2006) Methods Enzymol. 413, 122-139
30. Hubbell, W. L., Cafiso, D. S., and Altenbach, C. (2000) Nat. Struct. Biol. 7, 735-739
31. Jayasinghe, S. A., and Langen, R. (2004) J. Biol. Chem. 279, 48420-48425
32. Wood, S. J., Wypych, J., Steavenson, S., Louis, J. C., Citron, M., and Biere, A. L. (1999) J. Biol. Chem. 274, 19509-19512
33. Altenbach, C., Greenhalgh, D. A., Khorana, H. G., and Hubbell, W. L. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 1667-1671
34. Altenbach, C., Oh, K. J., Trabanino, R. J., Hideg, K., and Hubbell, W. L. (2001) Biochemistry 40, 15471-15482
35. Margittai, M., and Langen, R. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 10278-10283
36. Margittai, M., and Langen, R. (2006) J. Biol. Chem. 281, 37820-37827
37. Molin, Y. N., Salikhov, K. M., and Zamaraev, K. I. (1980) Spin Exchange, Springer-Verlag, Berlin
38. Masuda, M., Dohmae, N., Nonaka, T., Oikawa, T., Hisanaga, S., Goedert, M., and Hasegawa, M. (2006) FEBS Lett. 580, 1775-1779
39. Kaylor, J., Bodner, N., Edridge, S., Yamin, G., Hong, D. P., and Fink, A. L. (2005) J. Mol. Biol. 353, 357-372
40. Crowther, R. A., Jakes, R., Spillantini, M. G., and Goedert, M. (1998) FEBS Lett. 436, 309-312
41. Murray, I. V., Giasson, B. I., Quinn, S. M., Koppaka, V., Axelsen, P. H., Ischiropoulos, H., Trojanowski, J. Q., and Lee, V. M. (2003) Biochemistry 42, 8530-8540
42. Li, W., West, N., Colla, E., Pletnikova, O., Troncoso, J. C., Marsh, L., Dawson, T. M., Jakala, P., Hartmann, T., Price, D. L., and Lee, M. K. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 2162-2167
43. Hoyer, W., Cherny, D., Subramaniam, V., and Jovin, T. M. (2004) Biochemistry 43, 16233-16242
44. Hoyer, W., Cherny, D., Subramaniam, V., and Jovin, T. M. (2004) J. Mol. Biol. 340, 127-139
45. Liu, C. W., Giasson, B. I., Lewis, K. A., Lee, V. M., Demartino, G. N., and Thomas, P. J. (2005) J. Biol. Chem. 280, 22670-22678
46. Du, H. N., Tang, L., Luo, X. Y., Li, H. T., Hu, J., Zhou, J. W., and Hu, H. Y. (2003) Biochemistry 42, 8870-8878
47. Weinreb, P. H., Zhen, W., Poon, A. W., Conway, K. A., and Lansbury, P. T., Jr. (1996) Biochemistry 35, 13709-13715
48. Bertoncini, C. W., Jung, Y. S., Fernandez, C. O., Hoyer, W., Griesinger, C., Jovin, T. M., and Zweckstetter, M. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 1430-1435
49. Dedmon, M. M., Lindorff-Larsen, K., Christodoulou, J., Vendruscolo, M., and Dobson, C. M. (2005) J. Am. Chem. Soc 127, 476-477
50. Langen, R., Isas, J. M., Luecke, H., Haigler, H. T., and Hubbell, W. L. (1998) J. Biol. Chem. 273, 22453-22457
51. Gross, A., Columbus, L., Hideg, K., Altenbach, C., and Hubbell, W. L. (1999) Biochemistry 38, 10324-10335
52. Pake, G. E. (1948) J. Chem. Phys. 16, 327-336
53. Rabenstein, M. D., and Shin, Y. K. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8239-8243
54. Hustedt, E. J., Smirnov, A. I., Laub, C. F., Cobb, C. E., and Beth, A. H. (1997) Biophys. J. 72, 1861-1877
55. Berriman, J., Serpell, L. C., Oberg, K. A., Fink, A. L., Goedert, M., and Crowther, R. A. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 9034-9038
56. von Bergen, M., Barghorn, S., Li, L., Marx, A., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (2001) J. Biol. Chem. 276, 48165-48174
57. Mchaourab, H. S., Lietzow, M. A., Hideg, K., and Hubbell, W. L. (1996) Biochemistry 35, 7692-7704
58. Torok, M., Milton, S., Kayed, R., Wu, P., McIntire, T., Glabe, C. G., and Langen, R. (2002) J. Biol. Chem. 277, 40810-40815
59. Luckhurst, G. R. (1966) Mol. Phys. 10, 543-550
60. Hanson, P., Millhauser, G., Formaggio, F., Crisma, M., and Toniolo, C. (1996) J. Am. Chem. Soc 118, 7618-7625
61. Langen, R., Oh, K. J., Cascio, D., and Hubbell, W. L. (2000) Biochemistry 39, 8396-8405
62. Lajzerowicz-Bonneteau, J. (1976) Spin Labeling Theory and Applications, pp. 239-249, Academic Press
63. Iwata, K., Fujiwara, T., Matsuki, Y., Akutsu, H., Takahashi, S., Naiki, H., and Goto, Y. (2006) Proc. Natl. Acad. Sci. U. S. A.
64. Shewmaker, F., Wickner, R. B., and Tycko, R. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 19754-19759
65. Chan, J. C., Oyler, N. A., Yau, W. M., and Tycko, R. (2005) Biochemistry 44, 10669-10680
66. Benzinger, T. L., Gregory, D. M., Burkoth, T. S., Miller-Auer, H., Lynn, D. G., Botto, R. E., and Meredith, S. C. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13407-13412
67. Antzutkin, O. N., Balbach, J. J., Leapman, R. D., Rizzo, N. W., Reed, J., and Tycko, R. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 13045-13050
68. Nelson, R., Sawaya, M. R., Balbirnie, M., Madsen, A. O., Riekel, C., Grothe, R., and Eisenberg, D. (2005) Nature 435, 773-778
69. Giasson, B. I., Murray, I. V., Trojanowski, J. Q., and Lee, V. M. (2001) J. Biol. Chem. 276, 2380-2386
70. Pawar, A. P., Dubay, K. F., Zurdo, J., Chiti, F., Vendruscolo, M., and Dobson, C. M. (2005) J. Mol. Biol. 350, 379-392