Mapping long-range interactions in α-synuclein using spin-label NMR and ensemble molecular dynamics simulations

Journal of the American Chemical Society

Volumn 127, Issue 2, 2005, Pages 476-477

  Dedmon, Matthew M ^a   Lindorff Larsen, Kresten ^a   Christodoulou, John ^a   Vendruscolo, Michele ^a   Dobson, Christopher M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN;

AMINO ACID SEQUENCE; ARTICLE; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; OXIDATION; PROTEIN ANALYSIS; PROTEIN STRUCTURE; REDUCTION; SIMULATION; SPIN LABELING;

ALPHA-SYNUCLEIN; COMPUTER SIMULATION; LIGANDS; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; SYNUCLEINS;

EID: 12944304172     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja044834j     Document Type: Article

References (22)

1. Tompa, P. Trends Biochem. Sci. 2002, 27, 527-533.
2. Dunker, A. K.; Brown, C. J.; Lawson, J. D.; Iakoucheva, L. M.; Obradovic, Z. Biochemistry 2002, 41, 6573-6582.
3. Dyson, H. J.; Wright, P. E. Curr. Opin. Struct. Biol. 2002, 12, 54-60.
4. Uversky, V. N.; Fink, A. L. Biochim. Biophys. Acta 2004, 1698, 131-153.
5. Ross, C. A.; Poirier, M. A. Nat. Med. 2004, 10, S10-S17.
6. Gillespie, J. R.; Shortle, D. J. Mol. Biol. 1997, 268, 158-169.
7. Shortle, D.; Ackerman, M. S. Science 2001, 293, 487-489.
8. Klein-Seetharaman, J.; Oikawa, M.; Grimshaw, S. B.; Wirmer, J.; Duchardt, E.; Ueda, T.; Imoto, T.; Smith, L. J.; Dobson, C. M.; Schwalbe, H. Science 2002, 295, 1719-1722.
9. Lietzow, M. A.; Jamin, M.; Dyson, J.; Wright, P. E. J. Mol. Biol. 2002, 322, 655-662.
10. Teilum, K.; Kragelund, B. B.; Poulsen, F. M. J. Mol. Biol. 2002, 324, 349-357.
11. Lindorff-Larsen, K.; Kristjansdottir, S.; Teilum, K.; Fieber, W.; Dobson, C. M.; Poulsen, F. M.; Vendruscolo, M. J. Am. Chem. Soc. 2004, 126, 3291-3299.
12. Dobson, C. M. Nature 2003, 426, 884-890.
13. Dill, K. A.; Shortle, D. Annu. Rev. Biochem. 1991, 60, 795-825.
14. Morar, A. S.; Olteanu, A.; Young, G. B.; Pielak, G. J. Protein Sci. 2001, 10, 2195-2199.
15. Wilkins, D. K.; Grimshaw, S. B.; Receveur, V.; Dobson, C. M.; Jones, J. A.; Smith, L. J. Biochemistry 1999, 38, 16424-16431.
16. El-Agnaf, O.; Irvine, G. Biochem. Soc. Trans. 2001, 30, 559-565.
17. Der-Sarkissian, A.; Jao, C. C.; Chen, J.; Langen, R. J. Biol. Chem. 2003, 278, 37530-37535.
18. Crowther, R. A.; Jakes, R.; Spillantini, M. G.; Goedert, M. FEBS Lett. 1998, 436, 309-312.
19. Baba, M.; Nakajo, S.; Tu, P. H.; Tomita, T.; Nakaya, K.; Lee, V. M.; Trojanowski, J. Q.; Iwatsubo, T. Am. J. Pathol. 1998, 152, 879-884.
20. Uversky, V. N. J. Biomol. Struct. Dyn. 2003, 21, 211-234.
21. Antony, T.; Hoyer, W.; Cherny, D.; Heim, G.; Jovin, T. M.; Subramaniam, V. J. Biol. Chem. 2003, 278, 3235-3240.
22. Fernandez, C.; Hoyer, W.; Zweckstetter, M.; Jares-Erijman, E.; Subramaniam, V.; Griesinger, C.; Jovin, T. EMBO J. 2004, 23, 2039-2046.