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Journal of the American Chemical Society

Volumn 123, Issue 27, 2001, Pages 6465-6474

Assessing the balance between protein-protein interactions and enzyme-substrate interactions in the channeling of intermediates between polyketide synthase modules

(4) Wu, N a Tsuji, S Y b Cane, D E c Khosla, C a,b

a STANFORD UNIVERSITY (United States)

b Stanford University (United States)

c BROWN UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN-PROTEIN INTERACTIONS;

BIOASSAY; BIOSYNTHESIS; CATALYSIS; ORGANIC COMPOUNDS; SUBSTRATES;

ENZYMES;

6 DEOXYERYTHRONOLIDE B; 6 DEOXYERYTHRONOLIDE B SYNTHASE; CYSTEAMINE DERIVATIVE; ERYTHROMYCIN; ERYTHRONOLIDE DERIVATIVE; N ACETYLCYSTEAMINE THIOESTER; POLYKETIDE SYNTHASE; PRODRUG; THIOESTER; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; BIOSYNTHESIS; COVALENT BOND; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MOLECULAR RECOGNITION; PROTEIN PROTEIN INTERACTION; STEADY STATE; STEREOCHEMISTRY;

ACYL CARRIER PROTEIN; CATALYTIC DOMAIN; ELECTRON TRANSPORT; KINETICS; MULTIENZYME COMPLEXES; PEPTIDES; PROTEIN BINDING; PROTEIN ENGINEERING; SUBSTRATE SPECIFICITY;

EID: 0034809381 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja010219t Document Type: Article

Times cited : (121)

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