-
1
-
-
50349143880
-
Absorption and excretion of iron
-
McCance R.A., and Widdowson E.M. Absorption and excretion of iron. Lancet 2 (1937) 680-684
-
(1937)
Lancet
, vol.2
, pp. 680-684
-
-
McCance, R.A.1
Widdowson, E.M.2
-
2
-
-
0004592939
-
-
Grune & Stratton, Inc., New York
-
Beutler E., Fairbanks V.F., and Fahey J.L. Clinical Disorders of Iron Metabolism (1963), Grune & Stratton, Inc., New York
-
(1963)
Clinical Disorders of Iron Metabolism
-
-
Beutler, E.1
Fairbanks, V.F.2
Fahey, J.L.3
-
3
-
-
0001537486
-
Radioactive iron absorption by gastro-intestinal tract: influence of anemia, anoxia, and antecedent feeding
-
Hahn P.F., Bale W.F., Ross J.F., et al. Radioactive iron absorption by gastro-intestinal tract: influence of anemia, anoxia, and antecedent feeding. J. Exp. Med. 78 (1943) 169-188
-
(1943)
J. Exp. Med.
, vol.78
, pp. 169-188
-
-
Hahn, P.F.1
Bale, W.F.2
Ross, J.F.3
-
4
-
-
0642287962
-
History of iron in medicine
-
Beutler E. History of iron in medicine. Blood Cells Mol. Diseases 29 (2002) 297-308
-
(2002)
Blood Cells Mol. Diseases
, vol.29
, pp. 297-308
-
-
Beutler, E.1
-
5
-
-
33750133047
-
Regulation of iron metabolism by hepcidin
-
Nemeth E., and Ganz T. Regulation of iron metabolism by hepcidin. Annu. Rev. Nutr. 26 (2006) 323-342
-
(2006)
Annu. Rev. Nutr.
, vol.26
, pp. 323-342
-
-
Nemeth, E.1
Ganz, T.2
-
6
-
-
10844258104
-
Hepcidin regulates iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E., Tuttle M.S., Powelson J., et al. Hepcidin regulates iron efflux by binding to ferroportin and inducing its internalization. Science 306 (2004) 2090-2093
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
-
7
-
-
0035902605
-
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
-
Nicolas G., Bennoun M., Devaux I., et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 8780-8785
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 8780-8785
-
-
Nicolas, G.1
Bennoun, M.2
Devaux, I.3
-
8
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
Pigeon C., Ilyin G., Courselaud B., et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J. Biol. Chem. 276 (2001) 7811-7819
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
-
9
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou G., Samuels M.E., Ludwig E.H., et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat. Genet. 36 (2004) 77-82
-
(2004)
Nat. Genet.
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
Samuels, M.E.2
Ludwig, E.H.3
-
10
-
-
13544250486
-
Hepcidin is decreased in TFR2 hemochromatosis
-
Nemeth E., Roetto A., Garozzo G., et al. Hepcidin is decreased in TFR2 hemochromatosis. Blood 105 (2005) 1803-1806
-
(2005)
Blood
, vol.105
, pp. 1803-1806
-
-
Nemeth, E.1
Roetto, A.2
Garozzo, G.3
-
11
-
-
33749393565
-
Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing
-
Goswami T., and Andrews N.C. Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing. J. Biol. Chem. 281 (2006) 28494-28498
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 28494-28498
-
-
Goswami, T.1
Andrews, N.C.2
-
12
-
-
33745898241
-
Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6
-
Truksa J., Peng H., Gelbart T., et al. Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 10289-10293
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 10289-10293
-
-
Truksa, J.1
Peng, H.2
Gelbart, T.3
-
13
-
-
33751281494
-
Soluble transferrin receptor-1 levels in mice do not affect iron absorption
-
Flanagan J.M., Peng H., Wang L., et al. Soluble transferrin receptor-1 levels in mice do not affect iron absorption. Acta Haematol. (Basel) 116 (2006) 249-254
-
(2006)
Acta Haematol. (Basel)
, vol.116
, pp. 249-254
-
-
Flanagan, J.M.1
Peng, H.2
Wang, L.3
-
14
-
-
34547157362
-
Down regulation of hepcidin and haemojuvelin expression in the hepatocyte cell-line HepG2 induced by thalassaemic sera
-
Weizer-Stern O., Adamsky K., Amariglio N., et al. Down regulation of hepcidin and haemojuvelin expression in the hepatocyte cell-line HepG2 induced by thalassaemic sera. Blood 108 (2006) 447a
-
(2006)
Blood
, vol.108
-
-
Weizer-Stern, O.1
Adamsky, K.2
Amariglio, N.3
-
15
-
-
27144459908
-
Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin
-
Lin L., Goldberg Y.P., and Ganz T. Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin. Blood 106 (2005) 2884-2889
-
(2005)
Blood
, vol.106
, pp. 2884-2889
-
-
Lin, L.1
Goldberg, Y.P.2
Ganz, T.3
-
16
-
-
34250308049
-
Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin
-
Zhang A.S., Anderson S.A., Meyers K.R., et al. Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin. J. Biol. Chem. (2007) M608788200
-
(2007)
J. Biol. Chem.
-
-
Zhang, A.S.1
Anderson, S.A.2
Meyers, K.R.3
-
17
-
-
0004241915
-
-
Oxford University Press, London
-
Sheldon J.H. Haemochromatosis (1935), Oxford University Press, London
-
(1935)
Haemochromatosis
-
-
Sheldon, J.H.1
-
18
-
-
0001480079
-
The effect of repeated phlebotomies in hemochromatosis
-
Davis W.D., and Arrowsmith W.R. The effect of repeated phlebotomies in hemochromatosis. J. Lab. Clin. Med. 39 (1952) 526-532
-
(1952)
J. Lab. Clin. Med.
, vol.39
, pp. 526-532
-
-
Davis, W.D.1
Arrowsmith, W.R.2
-
19
-
-
0005200207
-
Iron metabolism in hemochromatosis
-
Finch C. Iron metabolism in hemochromatosis. J. Clin. Invest. 28 (1949) 780
-
(1949)
J. Clin. Invest.
, vol.28
, pp. 780
-
-
Finch, C.1
-
20
-
-
0016848003
-
Hémochromatose idiopathique: maladie associée à l'antigène tissulaire
-
Simon M., Pawlotsky Y., Bourel M., et al. Hémochromatose idiopathique: maladie associée à l'antigène tissulaire. Nouv. Presse Med. 4 (1975) 1432
-
(1975)
Nouv. Presse Med.
, vol.4
, pp. 1432
-
-
Simon, M.1
Pawlotsky, Y.2
Bourel, M.3
-
21
-
-
0017158302
-
Association of HLA-A3 and HLA-B14 antigens with idiopathic hemochromatosis
-
Simon M., Bourel R., Fauchet R., and Genetet B. Association of HLA-A3 and HLA-B14 antigens with idiopathic hemochromatosis. Gut 17 (1976) 332-334
-
(1976)
Gut
, vol.17
, pp. 332-334
-
-
Simon, M.1
Bourel, R.2
Fauchet, R.3
Genetet, B.4
-
22
-
-
9344224529
-
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
-
Feder J.N., Gnirke A., Thomas W., et al. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat. Genet. 13 (1996) 399-408
-
(1996)
Nat. Genet.
, vol.13
, pp. 399-408
-
-
Feder, J.N.1
Gnirke, A.2
Thomas, W.3
-
23
-
-
0029029626
-
Screening blood donors for hereditary hemochromatosis: decision analysis model based on a 30-year database
-
Adams P.C., Gregor J.C., Kertesz A.E., and Valberg L.S. Screening blood donors for hereditary hemochromatosis: decision analysis model based on a 30-year database. Gastroenterology 109 (1995) 177-188
-
(1995)
Gastroenterology
, vol.109
, pp. 177-188
-
-
Adams, P.C.1
Gregor, J.C.2
Kertesz, A.E.3
Valberg, L.S.4
-
24
-
-
0035002163
-
Population screening for HFE-associated haemochromatosis: should we have to pay for our genes?
-
Yapp T.R., Eijkelkamp E.J., and Powell L.W. Population screening for HFE-associated haemochromatosis: should we have to pay for our genes?. Intern. Med. J. 31 (2001) 48-52
-
(2001)
Intern. Med. J.
, vol.31
, pp. 48-52
-
-
Yapp, T.R.1
Eijkelkamp, E.J.2
Powell, L.W.3
-
25
-
-
0034649789
-
Screening for hereditary haemochromatosis should be implemented now
-
Allen K., and Williamson R. Screening for hereditary haemochromatosis should be implemented now. BMJ 320 (2000) 183-184
-
(2000)
BMJ
, vol.320
, pp. 183-184
-
-
Allen, K.1
Williamson, R.2
-
26
-
-
0001089987
-
EASL International Consensus Conference on Haemochromatosis: Part II. Expert document
-
Adams P., Brissot P., and Powell L. EASL International Consensus Conference on Haemochromatosis: Part II. Expert document. J. Hepatol. 33 (2000) 487-496
-
(2000)
J. Hepatol.
, vol.33
, pp. 487-496
-
-
Adams, P.1
Brissot, P.2
Powell, L.3
-
27
-
-
0034609577
-
The effect of HFE genotypes in patients attending a health appraisal clinic
-
Beutler E., Felitti V., Gelbart T., and Ho N. The effect of HFE genotypes in patients attending a health appraisal clinic. Ann. Intern. Med. 133 (2000) 329-337
-
(2000)
Ann. Intern. Med.
, vol.133
, pp. 329-337
-
-
Beutler, E.1
Felitti, V.2
Gelbart, T.3
Ho, N.4
-
28
-
-
0037132786
-
Penetrance of the 845G->A (C282Y) HFE hereditary haemochromatosis mutation in the USA
-
Beutler E., Felitti V.J., Koziol J.A., et al. Penetrance of the 845G->A (C282Y) HFE hereditary haemochromatosis mutation in the USA. Lancet 359 (2002) 211-218
-
(2002)
Lancet
, vol.359
, pp. 211-218
-
-
Beutler, E.1
Felitti, V.J.2
Koziol, J.A.3
-
29
-
-
0036264177
-
Prevalence of hemochromatosis-related symptoms in homozygotes for the C282Y mutation of the HFE gene
-
Waalen J., Felitti V., Gelbart T., et al. Prevalence of hemochromatosis-related symptoms in homozygotes for the C282Y mutation of the HFE gene. Mayo Clin. Proc. 77 (2002) 522-530
-
(2002)
Mayo Clin. Proc.
, vol.77
, pp. 522-530
-
-
Waalen, J.1
Felitti, V.2
Gelbart, T.3
-
31
-
-
34547154545
-
Disorders of iron metabolism
-
Lichtman M.A., Beutler E., Kipps T.J., Seligsohn U., Kaushansky K., and Prchal J. (Eds), McGraw-Hill, New York
-
Beutler E. Disorders of iron metabolism. In: Lichtman M.A., Beutler E., Kipps T.J., Seligsohn U., Kaushansky K., and Prchal J. (Eds). Williams Hematology (2006), McGraw-Hill, New York 511-553
-
(2006)
Williams Hematology
, pp. 511-553
-
-
Beutler, E.1
-
32
-
-
0346553006
-
Clinical haemochromatosis in HFE carriers
-
Cox T., Rochette J., Camaschella C., et al. Clinical haemochromatosis in HFE carriers. Lancet 360 (2002) 412
-
(2002)
Lancet
, vol.360
, pp. 412
-
-
Cox, T.1
Rochette, J.2
Camaschella, C.3
-
33
-
-
0346553006
-
Clinical haemochromatosis in HFE carriers
-
Allen K.J., Warner B., and Delatycki M.B. Clinical haemochromatosis in HFE carriers. Lancet 360 (2002) 412-413
-
(2002)
Lancet
, vol.360
, pp. 412-413
-
-
Allen, K.J.1
Warner, B.2
Delatycki, M.B.3
-
34
-
-
17944369464
-
Screening for hemochromatosis: high prevalence and low morbidity in an unselected population of 65,238 persons
-
Åsberg A., Hveem K., Thorstensen K., et al. Screening for hemochromatosis: high prevalence and low morbidity in an unselected population of 65,238 persons. Scand. J. Gastroenterol. 36 (2001) 1108-1115
-
(2001)
Scand. J. Gastroenterol.
, vol.36
, pp. 1108-1115
-
-
Åsberg, A.1
Hveem, K.2
Thorstensen, K.3
-
35
-
-
20244372858
-
Hemochromatosis and iron-overload screening in a racially diverse population
-
Adams P.C., Reboussin D.M., Barton J.C., et al. Hemochromatosis and iron-overload screening in a racially diverse population. N. Engl. J. Med. 352 (2005) 1769-1778
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 1769-1778
-
-
Adams, P.C.1
Reboussin, D.M.2
Barton, J.C.3
-
36
-
-
0035525732
-
Discrepancies between genotype and phenotype in hematology: an important frontier
-
Beutler E. Discrepancies between genotype and phenotype in hematology: an important frontier. Blood 98 (2001) 2597-2602
-
(2001)
Blood
, vol.98
, pp. 2597-2602
-
-
Beutler, E.1
-
37
-
-
0035065510
-
Retrotransposons as epigenetic mediators of phenotypic variation in mammals
-
Whitelaw E., and Martin D.I. Retrotransposons as epigenetic mediators of phenotypic variation in mammals. Nat. Genet. 27 (2001) 361-365
-
(2001)
Nat. Genet.
, vol.27
, pp. 361-365
-
-
Whitelaw, E.1
Martin, D.I.2
-
38
-
-
34547165796
-
Idiopathic hemochromatosis: a variant of portal cirrhosis and idiopathic hemosiderosis
-
MacDonald R.A. Idiopathic hemochromatosis: a variant of portal cirrhosis and idiopathic hemosiderosis. Arch. Intern. Med. 107 (1961) 606-616
-
(1961)
Arch. Intern. Med.
, vol.107
, pp. 606-616
-
-
MacDonald, R.A.1
-
39
-
-
0008312813
-
Idiopathic hemochromatosis. Genetic or acquired?
-
MacDonald R.A. Idiopathic hemochromatosis. Genetic or acquired?. Arch. Intern. Med. 112 (1963) 82-88
-
(1963)
Arch. Intern. Med.
, vol.112
, pp. 82-88
-
-
MacDonald, R.A.1
-
40
-
-
0018864571
-
Idiopathic hemochromatosis, an interim report
-
Milder M.S., Cook J.D., Stray S., and Finch C.A. Idiopathic hemochromatosis, an interim report. Medicine 59 (1980) 34-49
-
(1980)
Medicine
, vol.59
, pp. 34-49
-
-
Milder, M.S.1
Cook, J.D.2
Stray, S.3
Finch, C.A.4
-
41
-
-
0037818787
-
Hereditary hemochromatosis: effect of excessive alcohol consumption on disease expression in patients homozygous for the C282Y mutation
-
Scotet V., Merour M.C., Mercier A.Y., et al. Hereditary hemochromatosis: effect of excessive alcohol consumption on disease expression in patients homozygous for the C282Y mutation. Am. J. Epidemiol. 158 (2003) 129-134
-
(2003)
Am. J. Epidemiol.
, vol.158
, pp. 129-134
-
-
Scotet, V.1
Merour, M.C.2
Mercier, A.Y.3
-
42
-
-
0036163634
-
Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis
-
Fletcher L.M., Dixon J.L., Purdie D.M., et al. Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis. Gastroenterology 122 (2002) 281-289
-
(2002)
Gastroenterology
, vol.122
, pp. 281-289
-
-
Fletcher, L.M.1
Dixon, J.L.2
Purdie, D.M.3
-
43
-
-
33845864447
-
Effects of alcohol consumption on iron metabolism in mice with hemochromatosis mutations
-
Flanagan J.M., Peng H., and Beutler E. Effects of alcohol consumption on iron metabolism in mice with hemochromatosis mutations. Alcohol Clin. Exp. Res. 31 (2006) 138-143
-
(2006)
Alcohol Clin. Exp. Res.
, vol.31
, pp. 138-143
-
-
Flanagan, J.M.1
Peng, H.2
Beutler, E.3
-
44
-
-
33747359666
-
Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression
-
Harrison-Findik D.D., Schafer D., Klein E., et al. Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression. J. Biol. Chem. 281 (2006) 22974-22982
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 22974-22982
-
-
Harrison-Findik, D.D.1
Schafer, D.2
Klein, E.3
-
45
-
-
27744561330
-
Diet and genetic factors associated with iron status in middle-aged women
-
Cade J.E., Moreton J.A., O'hara B., et al. Diet and genetic factors associated with iron status in middle-aged women. Am. J. Clin. Nutr. 82 (2005) 813-820
-
(2005)
Am. J. Clin. Nutr.
, vol.82
, pp. 813-820
-
-
Cade, J.E.1
Moreton, J.A.2
O'hara, B.3
-
46
-
-
33645969263
-
HFE genotypes and dietary heme iron: No evidence of strong gene-nutrient interaction on serum ferritin concentrations in middle-aged women
-
van der A D.L., Peeters P.H., Grobbee D.E., et al. HFE genotypes and dietary heme iron: No evidence of strong gene-nutrient interaction on serum ferritin concentrations in middle-aged women. Nutr. Metab. Cardiovasc. Dis. 16 (2006) 60-68
-
(2006)
Nutr. Metab. Cardiovasc. Dis.
, vol.16
, pp. 60-68
-
-
van der A, D.L.1
Peeters, P.H.2
Grobbee, D.E.3
-
48
-
-
27744561637
-
Chronic inflammation does not appear to modify the homozygous hereditary hemochromatosis phenotype
-
Beutler E., Waalen J., and Gelbart T. Chronic inflammation does not appear to modify the homozygous hereditary hemochromatosis phenotype. Blood Cells Mol. Diseases 35 (2005) 326-327
-
(2005)
Blood Cells Mol. Diseases
, vol.35
, pp. 326-327
-
-
Beutler, E.1
Waalen, J.2
Gelbart, T.3
-
49
-
-
13944278864
-
Iron-deficiency anemia and Helicobacter pylori infection: a review of the evidence
-
Dubois S., and Kearney D.J. Iron-deficiency anemia and Helicobacter pylori infection: a review of the evidence. Am. J. Gastroenterol. 100 (2005) 453-459
-
(2005)
Am. J. Gastroenterol.
, vol.100
, pp. 453-459
-
-
Dubois, S.1
Kearney, D.J.2
-
50
-
-
33845601746
-
A hematologist's view of unexplained iron deficiency anemia in males: impact of Helicobacter pylori eradication
-
Hershko C. A hematologist's view of unexplained iron deficiency anemia in males: impact of Helicobacter pylori eradication. Blood Cells Mol. Diseases 38 (2007) 45-53
-
(2007)
Blood Cells Mol. Diseases
, vol.38
, pp. 45-53
-
-
Hershko, C.1
-
51
-
-
33750829204
-
Helicobacter pylori infection and HFE hemochromatosis
-
Beutler E., and Gelbart T. Helicobacter pylori infection and HFE hemochromatosis. Blood Cells Mol. Diseases 37 (2006) 188-191
-
(2006)
Blood Cells Mol. Diseases
, vol.37
, pp. 188-191
-
-
Beutler, E.1
Gelbart, T.2
-
52
-
-
0036893006
-
Haptoglobin polymorphism and iron homeostasis
-
Beutler E., Gelbart T., and Lee P. Haptoglobin polymorphism and iron homeostasis. Clin. Chem. 48 (2002) 2232-2235
-
(2002)
Clin. Chem.
, vol.48
, pp. 2232-2235
-
-
Beutler, E.1
Gelbart, T.2
Lee, P.3
-
55
-
-
0034966041
-
Polymorphisms in the transferrin 5′ flanking region associated with differences in total iron binding capacity: possible implications in iron homeostasis
-
Lee P.L., Halloran C., and Beutler E. Polymorphisms in the transferrin 5′ flanking region associated with differences in total iron binding capacity: possible implications in iron homeostasis. Blood Cells Mol. Diseases 27 (2001) 539-548
-
(2001)
Blood Cells Mol. Diseases
, vol.27
, pp. 539-548
-
-
Lee, P.L.1
Halloran, C.2
Beutler, E.3
-
56
-
-
0035206994
-
A study of genes that may modulate the expression of hereditary hemochromatosis: transferrin receptor-1, ferroportin, ceruloplasmin, ferritin light and heavy chains, iron regulatory proteins (IRP)-1 and -2, and hepcidin
-
Lee P.L., Gelbart T., West C., et al. A study of genes that may modulate the expression of hereditary hemochromatosis: transferrin receptor-1, ferroportin, ceruloplasmin, ferritin light and heavy chains, iron regulatory proteins (IRP)-1 and -2, and hepcidin. Blood Cells Mol. Diseases 27 (2001) 783-802
-
(2001)
Blood Cells Mol. Diseases
, vol.27
, pp. 783-802
-
-
Lee, P.L.1
Gelbart, T.2
West, C.3
-
57
-
-
0035049344
-
Mutation analysis of the transferrin receptor-2 gene in patients with iron overload
-
Lee P.L., Halloran C., West C., and Beutler E. Mutation analysis of the transferrin receptor-2 gene in patients with iron overload. Blood Cells Mol. Diseases 27 (2001) 285-289
-
(2001)
Blood Cells Mol. Diseases
, vol.27
, pp. 285-289
-
-
Lee, P.L.1
Halloran, C.2
West, C.3
Beutler, E.4
-
58
-
-
0013350026
-
Seeking candidate mutations that affect iron homeostasis
-
Lee P.L., Gelbart T., West C., et al. Seeking candidate mutations that affect iron homeostasis. Blood Cells Mol. Diseases 29 (2002) 471-487
-
(2002)
Blood Cells Mol. Diseases
, vol.29
, pp. 471-487
-
-
Lee, P.L.1
Gelbart, T.2
West, C.3
-
59
-
-
33746602284
-
Tumor necrosis factor-{alpha} -308G>A polymorphism modulates iron accumulation in patients with hereditary hemochromatosis
-
Krayenbuehl P.A., Maly F.E., Hersberger M., et al. Tumor necrosis factor-{alpha} -308G>A polymorphism modulates iron accumulation in patients with hereditary hemochromatosis. Clin. Chem. 52 8 (2006) 1552-1558
-
(2006)
Clin. Chem.
, vol.52
, Issue.8
, pp. 1552-1558
-
-
Krayenbuehl, P.A.1
Maly, F.E.2
Hersberger, M.3
-
60
-
-
1642367900
-
HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype
-
Jacolot S., Le Gac G., Scotet V., et al. HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype. Blood 103 (2004) 2835-2840
-
(2004)
Blood
, vol.103
, pp. 2835-2840
-
-
Jacolot, S.1
Le Gac, G.2
Scotet, V.3
-
61
-
-
4544314123
-
'The recently identified type 2A juvenile haemochromatosis gene (HJV), a second candidate modifier of the C282Y homozygous phenotype
-
Le Gac G., Scotet V., Ka C., et al. 'The recently identified type 2A juvenile haemochromatosis gene (HJV), a second candidate modifier of the C282Y homozygous phenotype. Hum. Mol. Genet. 13 (2004) 1913-1918
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1913-1918
-
-
Le Gac, G.1
Scotet, V.2
Ka, C.3
-
62
-
-
9144251568
-
The 16189 variant of mitochondrial DNA occurs more frequently in C282Y homozygotes with haemochromatosis than those without iron loading
-
Livesey K.J., Wimhurst V.L., Carter K., et al. The 16189 variant of mitochondrial DNA occurs more frequently in C282Y homozygotes with haemochromatosis than those without iron loading. J. Med. Genet. 41 (2004) 6-10
-
(2004)
J. Med. Genet.
, vol.41
, pp. 6-10
-
-
Livesey, K.J.1
Wimhurst, V.L.2
Carter, K.3
-
63
-
-
19944401844
-
The mitochondrial superoxide dismutase A16V polymorphism in the cardiomyopathy associated with hereditary haemochromatosis
-
Valenti L., Conte D., Piperno A., et al. The mitochondrial superoxide dismutase A16V polymorphism in the cardiomyopathy associated with hereditary haemochromatosis. J. Med. Genet. 41 (2004) 946-950
-
(2004)
J. Med. Genet.
, vol.41
, pp. 946-950
-
-
Valenti, L.1
Conte, D.2
Piperno, A.3
-
64
-
-
0038824897
-
Haptoglobin type neither influences iron accumulation in normal subjects nor predicts clinical presentation in HFE C282Y haemochromatosis: phenotype and genotype analysis
-
Carter K., Bowen D.J., McCune C.A., and Worwood M. Haptoglobin type neither influences iron accumulation in normal subjects nor predicts clinical presentation in HFE C282Y haemochromatosis: phenotype and genotype analysis. Br. J. Haematol. 122 (2003) 326-332
-
(2003)
Br. J. Haematol.
, vol.122
, pp. 326-332
-
-
Carter, K.1
Bowen, D.J.2
McCune, C.A.3
Worwood, M.4
-
65
-
-
0042929566
-
Tumour necrosis factor alpha and its promoter polymorphisms' role in the phenotypic expression of hemochromatosis
-
Distante S., Elmberg M., Haug K.B.F., et al. Tumour necrosis factor alpha and its promoter polymorphisms' role in the phenotypic expression of hemochromatosis. Scand. J. Gastroenterol. 38 (2003) 871-877
-
(2003)
Scand. J. Gastroenterol.
, vol.38
, pp. 871-877
-
-
Distante, S.1
Elmberg, M.2
Haug, K.B.F.3
-
66
-
-
10744225120
-
Digenic inheritance of mutations in HAMP and HFE results in different types of haemochromatosis
-
Merryweather-Clarke A.T., Cadet E., Bomford A., et al. Digenic inheritance of mutations in HAMP and HFE results in different types of haemochromatosis. Hum. Mol. Genet. 12 (2003) 2241-2247
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2241-2247
-
-
Merryweather-Clarke, A.T.1
Cadet, E.2
Bomford, A.3
-
67
-
-
0036241178
-
Haptoglobin polymorphism and body iron stores
-
Delanghe J.R., and Langlois M.R. Haptoglobin polymorphism and body iron stores. Clin. Chem. Lab. Med. 40 (2002) 212-216
-
(2002)
Clin. Chem. Lab. Med.
, vol.40
, pp. 212-216
-
-
Delanghe, J.R.1
Langlois, M.R.2
-
68
-
-
1642416424
-
Hepcidin, a candidate modifier of the hemochromatosis phenotype in mice
-
Nicolas G., Andrews N.C., Kahn A., and Vaulont S. Hepcidin, a candidate modifier of the hemochromatosis phenotype in mice. Blood 103 (2004) 2841-2843
-
(2004)
Blood
, vol.103
, pp. 2841-2843
-
-
Nicolas, G.1
Andrews, N.C.2
Kahn, A.3
Vaulont, S.4
-
69
-
-
0036708279
-
Concordance of iron indices in homozygote and heterozygote sibling pairs in hemochromatosis families: implications for family screening
-
Whiting P., Fletcher L., Dixon J., et al. Concordance of iron indices in homozygote and heterozygote sibling pairs in hemochromatosis families: implications for family screening. J. Hepatol. 37 (2002) 309
-
(2002)
J. Hepatol.
, vol.37
, pp. 309
-
-
Whiting, P.1
Fletcher, L.2
Dixon, J.3
-
70
-
-
0022368621
-
Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis
-
Niederau C., Fischer R., Sonnenberg A., et al. Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis. N. Engl. J. Med. 313 (1985) 1256-1262
-
(1985)
N. Engl. J. Med.
, vol.313
, pp. 1256-1262
-
-
Niederau, C.1
Fischer, R.2
Sonnenberg, A.3
-
71
-
-
0029913626
-
Long-term survival in patients with hereditary hemochromatosis
-
Niederau C., Fischer R., Puerschel A., et al. Long-term survival in patients with hereditary hemochromatosis. Gastroenterology 110 (1996) 1107-1119
-
(1996)
Gastroenterology
, vol.110
, pp. 1107-1119
-
-
Niederau, C.1
Fischer, R.2
Puerschel, A.3
-
73
-
-
0014447127
-
Venesection therapy in idiopathic haemochromatosis
-
Williams R., Smith P.M., Spicer E.J.F., et al. Venesection therapy in idiopathic haemochromatosis. Q. J. Med. 38 (1969) 1-16
-
(1969)
Q. J. Med.
, vol.38
, pp. 1-16
-
-
Williams, R.1
Smith, P.M.2
Spicer, E.J.F.3
-
74
-
-
0017060790
-
Klinik und Therapie der idiopathischen Hämochromatose. Erfahrungen bei 51 eigenen Fllen
-
Fischer R. Klinik und Therapie der idiopathischen Hämochromatose. Erfahrungen bei 51 eigenen Fllen. Leber Magen Darm 6 (1976) 316-329
-
(1976)
Leber Magen Darm
, vol.6
, pp. 316-329
-
-
Fischer, R.1
-
75
-
-
0013834355
-
The reversal of hemochromatotic cirrhosis by multiple phlebotomies. Report of a case
-
Knauer C.M., Gamble C.N., and Monroe L.S. The reversal of hemochromatotic cirrhosis by multiple phlebotomies. Report of a case. Gastroenterology 49 (1965) 667-671
-
(1965)
Gastroenterology
, vol.49
, pp. 667-671
-
-
Knauer, C.M.1
Gamble, C.N.2
Monroe, L.S.3
-
76
-
-
33747042226
-
Reversibility of hepatic fibrosis in treated genetic hemochromatosis: a study of 36 cases
-
Falize L., Guillygomarc'h A., Perrin M., et al. Reversibility of hepatic fibrosis in treated genetic hemochromatosis: a study of 36 cases. Hepatology 44 (2006) 472-477
-
(2006)
Hepatology
, vol.44
, pp. 472-477
-
-
Falize, L.1
Guillygomarc'h, A.2
Perrin, M.3
-
77
-
-
1642494711
-
Serum ferritin level predicts advanced hepatic fibrosis among U.S. patients with phenotypic hemochromatosis
-
Morrison E.D., Brandhagen D.J., Phatak P.D., et al. Serum ferritin level predicts advanced hepatic fibrosis among U.S. patients with phenotypic hemochromatosis. Ann. Intern. Med. 138 (2003) 627-633
-
(2003)
Ann. Intern. Med.
, vol.138
, pp. 627-633
-
-
Morrison, E.D.1
Brandhagen, D.J.2
Phatak, P.D.3
-
78
-
-
0036727322
-
Noninvasive prediction of cirrhosis in C282Y-linked hemochromatosis
-
Beaton M., Guyader D., Deugnier Y., et al. Noninvasive prediction of cirrhosis in C282Y-linked hemochromatosis. Hepatology 36 (2002) 673-678
-
(2002)
Hepatology
, vol.36
, pp. 673-678
-
-
Beaton, M.1
Guyader, D.2
Deugnier, Y.3
-
79
-
-
0031707469
-
Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis
-
Guyader D., Jacquelinet C., Moirand R., et al. Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis. Gastroenterology 115 (1998) 929-936
-
(1998)
Gastroenterology
, vol.115
, pp. 929-936
-
-
Guyader, D.1
Jacquelinet, C.2
Moirand, R.3
-
80
-
-
1842579593
-
Hemochromatosis mutations in the general population: iron overload progression rate
-
Andersen R.V., Tybjaerg-Hansen A., Appleyard M., et al. Hemochromatosis mutations in the general population: iron overload progression rate. Blood 103 (2004) 2914-2919
-
(2004)
Blood
, vol.103
, pp. 2914-2919
-
-
Andersen, R.V.1
Tybjaerg-Hansen, A.2
Appleyard, M.3
-
81
-
-
1442331192
-
Natural history of hemochromatosis
-
Beutler E. Natural history of hemochromatosis. Mayo Clin. Proc. 79 (2004) 305-306
-
(2004)
Mayo Clin. Proc.
, vol.79
, pp. 305-306
-
-
Beutler, E.1
-
82
-
-
1442282237
-
Evolution of untreated hereditary hemochromatosis in the Busselton population: a 17-year study
-
Olynyk J.K., Hagan S.E., Cullen D.J., et al. Evolution of untreated hereditary hemochromatosis in the Busselton population: a 17-year study. Mayo Clin. Proc. 79 (2004) 309-313
-
(2004)
Mayo Clin. Proc.
, vol.79
, pp. 309-313
-
-
Olynyk, J.K.1
Hagan, S.E.2
Cullen, D.J.3
-
83
-
-
0017142698
-
Long term results of venesection therapy in idiopathic haemochromatosis
-
Bomford A., and Williams R. Long term results of venesection therapy in idiopathic haemochromatosis. Q. J. Med. 180 (1976) 611-623
-
(1976)
Q. J. Med.
, vol.180
, pp. 611-623
-
-
Bomford, A.1
Williams, R.2
-
84
-
-
33646338600
-
Prognostic factors and survival in patients with hereditary hemochromatosis and cirrhosis
-
Beaton M., and Adams P.C. Prognostic factors and survival in patients with hereditary hemochromatosis and cirrhosis. Can. J. Gastroenterol. 20 (2006) 257-260
-
(2006)
Can. J. Gastroenterol.
, vol.20
, pp. 257-260
-
-
Beaton, M.1
Adams, P.C.2
-
85
-
-
0035127525
-
Increased cancer risk in a cohort of 230 patients with hereditary hemochromatosis in comparison to matched control patients with non-iron-related chronic liver disease
-
Fracanzani A.L., Conte D., Fraquelli M., et al. Increased cancer risk in a cohort of 230 patients with hereditary hemochromatosis in comparison to matched control patients with non-iron-related chronic liver disease. Hepatology 33 (2001) 647-651
-
(2001)
Hepatology
, vol.33
, pp. 647-651
-
-
Fracanzani, A.L.1
Conte, D.2
Fraquelli, M.3
-
86
-
-
0023808243
-
Primary hepatocellular carcinoma in idiopathic hemochromatosis after reversal of cirrhosis
-
Blumberg R.S., Chopra S., Ibrahim R., et al. Primary hepatocellular carcinoma in idiopathic hemochromatosis after reversal of cirrhosis. Gastroenterology 95 (1988) 1399-1402
-
(1988)
Gastroenterology
, vol.95
, pp. 1399-1402
-
-
Blumberg, R.S.1
Chopra, S.2
Ibrahim, R.3
-
87
-
-
0033821260
-
Hepatocellular carcinoma arising in non-cirrhotic liver in genetic haemochromatosis
-
Britto M.R.C., Thomas L.A., Balaratnam N., et al. Hepatocellular carcinoma arising in non-cirrhotic liver in genetic haemochromatosis. Scand. J. Gastroenterol. 35 (2000) 889-893
-
(2000)
Scand. J. Gastroenterol.
, vol.35
, pp. 889-893
-
-
Britto, M.R.C.1
Thomas, L.A.2
Balaratnam, N.3
-
88
-
-
0036673518
-
Hepatoma in a 40-year old male with hereditary hemochromatosis in the absence of cirrhosis. Implications of molecular diagnosis
-
Brage A., Tome S., Figueruela B., et al. Hepatoma in a 40-year old male with hereditary hemochromatosis in the absence of cirrhosis. Implications of molecular diagnosis. Rev. Esp. Enferm. Dig. 94 (2002) 493-499
-
(2002)
Rev. Esp. Enferm. Dig.
, vol.94
, pp. 493-499
-
-
Brage, A.1
Tome, S.2
Figueruela, B.3
-
89
-
-
34547225379
-
Risk of hepatocellular carcinoma associated with genetic haemochromatosis in the absence of cirrhosis: a retrospective cohort study
-
Dale S.P., Aithal G.P., Thomas J.A., et al. Risk of hepatocellular carcinoma associated with genetic haemochromatosis in the absence of cirrhosis: a retrospective cohort study. J. Hepatol. 44 (2006) S88
-
(2006)
J. Hepatol.
, vol.44
-
-
Dale, S.P.1
Aithal, G.P.2
Thomas, J.A.3
-
90
-
-
25444510407
-
Hepatocellular carcinoma and the penetrance of HFE C282Y mutations: a cross sectional study
-
Willis G., Bardsley V., Fellows I.W., et al. Hepatocellular carcinoma and the penetrance of HFE C282Y mutations: a cross sectional study. BMC Gastroenterol. 5 (2005) 17
-
(2005)
BMC Gastroenterol.
, vol.5
, pp. 17
-
-
Willis, G.1
Bardsley, V.2
Fellows, I.W.3
-
91
-
-
32644445055
-
Screening for hemochromatosis in asymptomatic subjects with or without a family history
-
Powell L.W., Dixon J.L., Ramm G.A., et al. Screening for hemochromatosis in asymptomatic subjects with or without a family history. Arch. Intern. Med. 166 (2006) 294-301
-
(2006)
Arch. Intern. Med.
, vol.166
, pp. 294-301
-
-
Powell, L.W.1
Dixon, J.L.2
Ramm, G.A.3
-
92
-
-
33646391919
-
Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassen a major: new data, new questions
-
Neufeld E.J. Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassen a major: new data, new questions. Blood 107 (2006) 3436-3441
-
(2006)
Blood
, vol.107
, pp. 3436-3441
-
-
Neufeld, E.J.1
-
93
-
-
34547151432
-
Different regulatory elements are required for response of hepcidin to IL-6 and BMP-9
-
(in press)
-
Truksa J., Lee P., Flanagan J., and Beutler E. Different regulatory elements are required for response of hepcidin to IL-6 and BMP-9. Br. J. Haematol. (2007) (in press)
-
(2007)
Br. J. Haematol.
-
-
Truksa, J.1
Lee, P.2
Flanagan, J.3
Beutler, E.4
|