Chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from streptomyces atroolivaceus S-140: Discrete, monofunctional adenylation enzyme and peptidyl carrier protein that directly load D-alanine

Journal of Biological Chemistry

Volumn 282, Issue 28, 2007, Pages 20273-20282

  Tang, Gong Li ^a   Cheng, Yi Qiang ^a   Shen, Ben ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATION; LEINAMYCIN; THIOESTER;

ANTIBIOTICS; BACTERIA; COVALENT BONDS; ESTERS; FERMENTATION; PROTEINS;

ENZYME KINETICS;

ALANINE; AMINO ACID; LEINAMYCIN; LNMP PROTEIN; LNMQ PROTEIN; PEPTIDYL CARRIER PROTEIN; THIOESTER; UNCLASSIFIED DRUG;

ADENYLATION; AMINOACYLATION; ARTICLE; BACTERIAL STRAIN; BIOCHEMISTRY; CATALYSIS; FERMENTATION; GENE CLUSTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RNA TRANSLATION; STREPTOMYCES; STREPTOMYCES ATRO OLIVACEUS;

ALANINE; BACTERIAL PROTEINS; CARRIER PROTEINS; GENES, BACTERIAL; LACTAMS; MACROLIDES; MULTIGENE FAMILY; PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT; PEPTIDE SYNTHASES; POLYKETIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; STREPTOMYCES; THIAZOLES; THIONES;

STREPTOMYCES; STREPTOMYCES ATROOLIVACEUS;

EID: 34547099608     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M702814200     Document Type: Article

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