Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide-polyketide antitumor drug bleomycin

Chemistry and Biology

Volumn 8, Issue 7, 2001, Pages 725-738

  Sánchez, César ^a   Du, Liangcheng ^a   Edwards, Daniel J ^a   Toney, Michael D ^a   Shen, Ben ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Acyl carrier protein; Bleomycin; Peptidyl carrier protein; Phosphopantetheinyl transferase; Streptomyces verticillus

Indexed keywords

ACYL CARRIER PROTEIN; BIOCHEMICAL PATHWAY; COENZYME A; COVALENT BOND; ENZYME ACTIVITY; FUNGAL ENZYME; GENE CLUSTER; GENETIC STRAIN; MOLECULAR CLONING; PANTETHEINE PHOSPHATE; PHOSPHOPANTETHEINYL TRANSFERASE; POLYMERASE CHAIN REACTION; PROTEIN METABOLISM; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; BLEOMYCIN; CARRIER PROTEINS; CLONING, MOLECULAR; KINETICS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; STREPTOMYCES; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

EID: 0034930478     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(01)00047-3     Document Type: Article

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