Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome

Journal of Pathology

Volumn 198, Issue 2, 2002, Pages 258-269

  Kerkelä, Erja ^a   Ala aho, Risto ^b   Klemi, Pekka ^c   Grénman, Seija ^c   Shapiro, Steven D ^d   Kähäri, Veli Matti ^b   Saarialho Kere, Ulpu ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

92 kDa gelantinase; Angiogenesis; Cancer; Macrophage; Matrilysin

Indexed keywords

ANGIOSTATIN; CD68 ANTIGEN; ELASTIN; GELATINASE B; MACROPHAGE ELASTASE; MATRILYSIN; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; VON WILLEBRAND FACTOR;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CANCER GRADING; CANCER GROWTH; CANCER SURVIVAL; CELL DIFFERENTIATION; CELL MIGRATION; CELL TRANSFORMATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MACROPHAGE; METASTASIS; NEUTROPHIL; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TUMOR CELL; VULVA CARCINOMA; WESTERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; FEMALE; GENE EXPRESSION; HUMANS; IN SITU HYBRIDIZATION; MACROPHAGES; MATRIX METALLOPROTEINASE 12; MATRIX METALLOPROTEINASE 7; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOVASCULARIZATION, PATHOLOGIC; PROGNOSIS; RNA, MESSENGER; RNA, NEOPLASM; SURVIVAL RATE; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; VULVAR NEOPLASMS;

EID: 0036772138     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1198     Document Type: Article

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