Invasive lobular and invasive ductal carcinoma of the breast show distinct patterns of vascular endothelial growth factor expression and angiogenesis

Journal of Pathology

Volumn 185, Issue 4, 1998, Pages 394-401

  Lee, Andrew H S ^a,b   Dublin, Edwin A ^a   Bobrow, Lynda G ^a   Poulsom, Richard ^c  

^a GUY S HOSPITAL   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Breast; Carcinoma; Neovascularization; Pathologic; Vascular endothelial growth factor

Indexed keywords

VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; BREAST CARCINOMA; CARCINOMA IN SITU; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NEOVASCULARIZATION (PATHOLOGY); PRIORITY JOURNAL; PROTEIN EXPRESSION;

BREAST; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, LOBULAR; ENDOTHELIAL GROWTH FACTORS; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; LYMPHOKINES; NEOPLASM INVASIVENESS; NEOVASCULARIZATION, PATHOLOGIC; RNA, MESSENGER; RNA, NEOPLASM; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0031868964     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199808)185:4<394::AID-PATH117>3.0.CO;2-S     Document Type: Article

References (36)

1. Dvorak HF, Brown LF, Detmar M, Dvorak AM. Vascular permeabilily factor/vascular endothelial growth factor, microvascular permeability, and angiogenesis. Am J Pathol 1995; 146: 1029-1039.
2. Kim KJ, Li B, Winer J, et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo (Letter). Nature 1993; 362: 841-844.
3. Millauer B, Shawver LK, Plate KH, Risau W, Ullrich A. Glioblastoma growth inhibited in vivo by a dominant-negative flk-1 mutant (Letter). Nature 1994; 367: 576-579.
4. Weidner N, Folkman J, Pozza F, et al. Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst 1992; 84: 1875-1887.
5. Horak ER, Leek R, Klenk N, et al. Angiogenesis, assessed by platelet/ endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer. Lancet 1992; 340: 1120-1124.
6. Guidi AJ, Fischer L, Harris JR, Schnitt SJ. Microvessel density and distribution in ductal carcinoma in situ of the breast. J Natl Cancer Inst 1994; 86: 614-619.
7. Lee AHS, Happertield LC, Bobrow LG, Millis RR. Angiogenesis and inflammation in ductal carcinoma in situ of the breast. J Pathol 1997; 181: 200-206.
8. Connolly DT, Heuvelman DM, Nelson R, et al. Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 1989; 84: 1470-1478.
9. Leung DW, Cachianes G, Kuang W-J, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989; 246: 1306-1309.
10. 2-terminal amino acid sequence of guinea pig tumorsecreted vascular permeability factor. Cancer Res 1990; 50: 1774-1778.
11. Brown LF, Berse B, Jackman RW, et al. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum Pathl 1995; 26: 86-91.
12. Toi M, Inada K, Suzuki H, Tominaga T. Tumor angiogenesis in breast cancer: its importance as a prognostic indicator and the association with vascular endothelial growth factor expression. Breast Cancer Res Treat 1995; 36: 193-204.
13. Yoshiji H, Gomez DE, Shibuya M, Thorgeirsson UP. Expression of vascular endothelial growth factor, its receptor, and other angiogenic factors in human breast cancer. Cancer Res 1996; 56: 2013-2016.
14. Anan K, Morisaki T, Katano M, et al Vascular endothelial growth factor and platelet-derived growth factor are potential angiogenic and metastatic factors in human breast cancer. Surgery 1996; 119: 333-339.
15. Freeman MR, Schneck FX, Gagnon ML, et al. Peripheral blood T lymphocytes and lymphocytes infiltrating human cancers express vascular endothelial growth factor: a potential role for T cells in angiogenesis. Cancer Res 1995; 55: 4140-4145.
16. Lewis CE, Leek R, Harris A, McGee JO'D. Cytokine regulation of angiogenesis in breast cancer: the role of tumor-associated macrophages. J Leukoc Biol 1995; 57: 747-751.
17. Zhang H-T, Craft P, Scott PAE, et al. Enhancement of tumor growth and vascular density by transfection of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells. J Natl Cancer Inst 1995; 87: 213-219.
18. Mattern J, Koomagi R, Volm M. Association of vascular endothelial growth factor expression with intratumoral microvessel density and tumour cell proliferation in human epidermoid lung carcinoma. Br J Cancer 1996; 73: 931-934.
19. Toi M, Kondo S, Suzuki H, et al. Quantitative analysis of vascular endothelial growth factor in primary breast cancer. Cancer 1996; 77: 1101-1106.
20. Anan K, lkubo A, Morisaki T, et al. Differential expression of vascular endothelial growth factor (VEGF) in invasive breast carcinomas (Abstract). FASEB J 1996; 10: A757.
21. Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Hisiopathology 1991; 19: 403-410.
22. Azzopardi JG. Problems in Breast Pathology. London: W. B. Saunders, 1979: 278-285, 328-333.
23. Holland R, Peterse JL, Millis RR, et al. Ductal carcinoma in situ: a proposal for a new classification. Semin Diagn Pathol 1994; 11: 167-180.
24. Cordeil JL, Falini B, Erber WN, et al. Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 1984; 32: 219-229.
25. Lee AHS, Happerfield LC, Millis RR, Bobrow LG. Inflammatory infiltrate in invasive lobular and ductal carcinoma of the breast. Br J Cancer 1996; 74: 796-801.
26. Berse B, Brown LF, Van De Water L, Dvorak HF, Senger DR. Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages and tumors. Mol Biol Cell 1992; 3: 211-220.
27. Zandvleit DWJ, Hanby AM, Austin CA, et al. Analysis of foetal expression sites of human type II DNA topoisomerase a and β mRNA by in situ hybridisation. Biochim Biophys Acta 1996; 1307: 239-247.
28. Senior PV, Critchley DR, Beck F, Walker RA, Varley JM. The localisation of laminin mRNA and protein in the postimplantation embryo and placenta of the mouse: an in situ hybridisation and immunocytochemical study. Development 1988; 104: 411-446.
29. Berx G, Cleton-Jansen A-M, Strumane K, et al. E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. Oncogene 1996; 13: 1919-1925.
30. Jones JL, Walker RA. Matrix metalloproteinase (MMP) in infiltrating ductal (IDC) and infiltrating lobular (ILC) breast carcinoma (Abstract). J Pathol 1997; 181: 5A.
31. Jain S, Fisher C, Smith P, Millis RR, Rubens RD. Patterns of metastatic breast cancer in relation to histological type. Eur J Cancer 1993; 29A: 2155-2157.
32. Nagy JA, Brown LF, Senger DR, et al. Pathogenesis of tumor stroma generation: a critical role for leaky blood vessels and fibrin deposition. Biochim Biophys Acta 1988; 948: 305-326.
33. Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis (Letter). Nature 1992; 359: 843-845.
34. Dvorak HF, Sioussat TM, Brown LF, et al. Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels. J Exp Med 1991; 174: 1275-1278.
35. Goto F, Goto K, Weindel K, Folkman J. Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels. Lab Invest 1993; 69: 508-517.
36. Toi M, Inada K, Hoshina S, Suzuki H, Kondo S, Tominaga T. Vascular endothelial growth factor and platelet-derived endothelial cell growth factor are frequently coexpressed in highly vascularised human breast cancer, Clin Cancer Res 1995; 1: 961-964.