메뉴 건너뛰기




Volumn 59, Issue 2, 2007, Pages 150-163

Versatile effects of sildenafil: Recent pharmacological applications

Author keywords

Antinociception; Memory enhancement; Neurogenesis; Pulmonary hypertension; Sildenafil

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; BETA INTERFERON; CALCIUM CHANNEL BLOCKING AGENT; CHOLINESTERASE INHIBITOR; CORTICOSTEROID; CYCLIC GMP DEPENDENT PROTEIN KINASE; DEXFENFLURAMINE; DEXTROMETHORPHAN; FENFLURAMINE; GALANTAMINE; GLATIRAMER; GUANYLATE CYCLASE; IMMUNOSUPPRESSIVE AGENT; INOTROPIC AGENT; KETAMINE; MEMANTINE; MITOXANTRONE; MUSCLE RELAXANT AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NITRIC OXIDE; OPIATE; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; TADALAFIL; VARDENAFIL; VASODILATOR AGENT;

EID: 34250778886     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (79)

References (128)
  • 1
    • 0013784893 scopus 로고
    • Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
    • Altman J, Das GD: Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol, 1965, 124, 319-335.
    • (1965) J Comp Neurol , vol.124 , pp. 319-335
    • Altman, J.1    Das, G.D.2
  • 2
    • 0025016199 scopus 로고
    • Birth of projection neurons in adult avian brain may be related to perceptual or motor learning
    • Alvarez-Buylla A, Kim, JR, Nottebohm F: Birth of projection neurons in adult avian brain may be related to perceptual or motor learning. Science, 1990, 249, 1444-1446.
    • (1990) Science , vol.249 , pp. 1444-1446
    • Alvarez-Buylla, A.1    Kim, J.R.2    Nottebohm, F.3
  • 3
    • 17444426707 scopus 로고    scopus 로고
    • Analysis of the mechanism underlying the peripheral antinociceptive action of sildenafil in the formalin test
    • Ambriz-Tututi M, Velazquez-Zamora DA, Urquiza-Marín H, Granodos-Soto V: Analysis of the mechanism underlying the peripheral antinociceptive action of sildenafil in the formalin test. Eur J Pharmacol, 2005, 512, 121-127.
    • (2005) Eur J Pharmacol , vol.512 , pp. 121-127
    • Ambriz-Tututi, M.1    Velazquez-Zamora, D.A.2    Urquiza-Marín, H.3    Granodos-Soto, V.4
  • 4
    • 0034849563 scopus 로고    scopus 로고
    • Pharmacology of penile erection
    • Andersson KE: Pharmacology of penile erection. Pharmacol Rev, 2001, 53, 417-450.
    • (2001) Pharmacol Rev , vol.53 , pp. 417-450
    • Andersson, K.E.1
  • 6
    • 0029003966 scopus 로고
    • Activity-dependent long-term enhancement of transmitter release by presynaptic 3′, 5′-cyclic GMP in cultured hippocampal neurons
    • Arancio O, Kandel ER, Hawkins RD: Activity-dependent long-term enhancement of transmitter release by presynaptic 3′, 5′-cyclic GMP in cultured hippocampal neurons. Nature, 1995, 376, 74-80.
    • (1995) Nature , vol.376 , pp. 74-80
    • Arancio, O.1    Kandel, E.R.2    Hawkins, R.D.3
  • 7
    • 33645657561 scopus 로고    scopus 로고
    • Diabetic peripheral neuropathic pain: Clinical and quality-of-life issues
    • Argoff CE, Cole BF, Fishbain DA, Irving GA: Diabetic peripheral neuropathic pain: clinical and quality-of-life issues. Mayo Clin Proc, 2006, 81, Suppl 4, S3-11.
    • (2006) Mayo Clin Proc , vol.81 , Issue.SUPPL. 4
    • Argoff, C.E.1    Cole, B.F.2    Fishbain, D.A.3    Irving, G.A.4
  • 9
    • 0032810944 scopus 로고    scopus 로고
    • The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences
    • Aytac IA, McKinlay JB, Krane RJ: The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int, 1999, 84, 50-56.
    • (1999) BJU Int , vol.84 , pp. 50-56
    • Aytac, I.A.1    McKinlay, J.B.2    Krane, R.J.3
  • 10
    • 0033372856 scopus 로고    scopus 로고
    • Effects of sildenafil on long-term retention of an inhibitory avoidance response in mice
    • Baratti CM, Boccia MM: Effects of sildenafil on long-term retention of an inhibitory avoidance response in mice. Behav Pharmacol, 1999, 10, 731-737.
    • (1999) Behav Pharmacol , vol.10 , pp. 731-737
    • Baratti, C.M.1    Boccia, M.M.2
  • 11
    • 4243121730 scopus 로고    scopus 로고
    • Specific localized expression of cGMP PDEs in Purkinje neurons and macrophages
    • Bender AT, Beavo JA: Specific localized expression of cGMP PDEs in Purkinje neurons and macrophages. Neurochem Int, 2004, 45, 853-857.
    • (2004) Neurochem Int , vol.45 , pp. 853-857
    • Bender, A.T.1    Beavo, J.A.2
  • 12
    • 0029926167 scopus 로고    scopus 로고
    • Hippocampal cGMP and cAMP are differentially involved in memory processing of inhibitory avoidance learning
    • Bernabeu R, Scmitz P, Faillace MP, Izquierdo I, Medina JH: Hippocampal cGMP and cAMP are differentially involved in memory processing of inhibitory avoidance learning. Neuroreport, 1996, 7, 585-588.
    • (1996) Neuroreport , vol.7 , pp. 585-588
    • Bernabeu, R.1    Scmitz, P.2    Faillace, M.P.3    Izquierdo, I.4    Medina, J.H.5
  • 13
    • 0030758721 scopus 로고    scopus 로고
    • Further evidence for the involvement of a hippocampal cGMP cGMP-dependent protein kinase cascade in memory consolidation
    • Bernabeu R, Schroder N, Quevedo J, Cammaroto M, Izquierdo I, Medina JH: Further evidence for the involvement of a hippocampal cGMP cGMP-dependent protein kinase cascade in memory consolidation. Neuroreport, 1997, 8, 2221-2224.
    • (1997) Neuroreport , vol.8 , pp. 2221-2224
    • Bernabeu, R.1    Schroder, N.2    Quevedo, J.3    Cammaroto, M.4    Izquierdo, I.5    Medina, J.H.6
  • 14
    • 42749100518 scopus 로고    scopus 로고
    • Birks J: Cholinesterase inhibitors for Alzheimer's disease. Cochrane Database Syst Rev, 2006, 25, CD0055593.
    • Birks J: Cholinesterase inhibitors for Alzheimer's disease. Cochrane Database Syst Rev, 2006, 25, CD0055593.
  • 15
    • 33745755921 scopus 로고    scopus 로고
    • Improving memory: A role for phosphodiesterases
    • Blokland A, Schreiber R, Prickaerts J: Improving memory: a role for phosphodiesterases. Curr Pharm Des, 2006, 12, 2511-2523.
    • (2006) Curr Pharm Des , vol.12 , pp. 2511-2523
    • Blokland, A.1    Schreiber, R.2    Prickaerts, J.3
  • 16
    • 0037338353 scopus 로고    scopus 로고
    • On the role of nitric oxide in hippocampal long-term potentiation
    • Bon CL, Garthwaite J: On the role of nitric oxide in hippocampal long-term potentiation. J. Neurosci, 2003, 23, 1941-1948.
    • (2003) J. Neurosci , vol.23 , pp. 1941-1948
    • Bon, C.L.1    Garthwaite, J.2
  • 17
    • 0030154874 scopus 로고    scopus 로고
    • Sildenafil: An orally active type 5 cGMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction
    • Boolell M, Allen MJ, Ballard SA, Gepi-Atree S, Muirhead GJ, Naylor AM, Osterloh IH et al.: Sildenafil: an orally active type 5 cGMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction. In: J Impot Res, 1996, 8, 47-52.
    • (1996) J Impot Res , vol.8 , pp. 47-52
    • Boolell, M.1    Allen, M.J.2    Ballard, S.A.3    Gepi-Atree, S.4    Muirhead, G.J.5    Naylor, A.M.6    Osterloh, I.H.7
  • 18
    • 0028788154 scopus 로고
    • Nitric oxide-dependent long-term potentiation is blocked by a specific inhibitor of soluble guanylyl cyclase
    • Boulton CL, Southam E, Garthwaite J: Nitric oxide-dependent long-term potentiation is blocked by a specific inhibitor of soluble guanylyl cyclase. Neuroscience, 1995, 69, 699-703.
    • (1995) Neuroscience , vol.69 , pp. 699-703
    • Boulton, C.L.1    Southam, E.2    Garthwaite, J.3
  • 19
    • 33746387831 scopus 로고    scopus 로고
    • The relationship between cognitive and brain changes in posttraumatic stress disorder
    • Bremner JD: The relationship between cognitive and brain changes in posttraumatic stress disorder. Ann N Y Acad Sci, 2006, 1071, 80-86.
    • (2006) Ann N Y Acad Sci , vol.1071 , pp. 80-86
    • Bremner, J.D.1
  • 21
    • 0028364703 scopus 로고
    • Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus
    • Cameron CA, Gould E: Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neuroscience, 1994, 61, 203-209.
    • (1994) Neuroscience , vol.61 , pp. 203-209
    • Cameron, C.A.1    Gould, E.2
  • 23
    • 1842665660 scopus 로고    scopus 로고
    • The localization of neuronal nitric oxide synthase may influence its role in neuronal precursor proliferation and synaptic Maintenance
    • Chen J, Tu Y, Moon C, Matarazzo V, Palmer AM, Ronett GV: The localization of neuronal nitric oxide synthase may influence its role in neuronal precursor proliferation and synaptic Maintenance. Dev Biol, 2004, 269, 165-182.
    • (2004) Dev Biol , vol.269 , pp. 165-182
    • Chen, J.1    Tu, Y.2    Moon, C.3    Matarazzo, V.4    Palmer, A.M.5    Ronett, G.V.6
  • 24
    • 3342962358 scopus 로고    scopus 로고
    • Mechanisms of action of PDE5 inhibition in erectile dysfunction
    • Corbin JD: Mechanisms of action of PDE5 inhibition in erectile dysfunction. Int J Impot Res, 2004, 16, Suppl 1, S4-7
    • (2004) Int J Impot Res , vol.16 , Issue.SUPPL. 1
    • Corbin, J.D.1
  • 26
    • 33746977177 scopus 로고    scopus 로고
    • Dean J, de Boer BJ, Graziottin A, Hatzichristou D, Heaton J, Tailor A: Psychological, social, and behavioural benefits for men following effective erectile dysfunction (ED) treatment: men who enjoy better sex experience improved psychological well-being. Eur Urol Suppl, 2006, 5, 773-778.
    • Dean J, de Boer BJ, Graziottin A, Hatzichristou D, Heaton J, Tailor A: Psychological, social, and behavioural benefits for men following effective erectile dysfunction (ED) treatment: men who enjoy better sex experience improved psychological well-being. Eur Urol Suppl, 2006, 5, 773-778.
  • 27
    • 28344453810 scopus 로고    scopus 로고
    • Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition
    • Devan BD, Bowker JL, Duffy KB, Bharati IS, Jimenez M, Sierra-Mereado D Jr, Nelson CM et al.: Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition. Psychopharmacology (Berl), 2006, 183, 439-445.
    • (2006) Psychopharmacology (Berl) , vol.183 , pp. 439-445
    • Devan, B.D.1    Bowker, J.L.2    Duffy, K.B.3    Bharati, I.S.4    Jimenez, M.5    Sierra-Mereado Jr, D.6    Nelson, C.M.7
  • 29
    • 10044297395 scopus 로고    scopus 로고
    • Phosphodiesterase inhibition by sildenafil citrate attenuates the learning impairment induced by blockade of cholinergic muscarinic receptors in rats
    • Devan BD, Sierra-Mercado D Jr, Jimenez M, BowKer JL, Duffy KB, Spangler EL, Ingram DK: Phosphodiesterase inhibition by sildenafil citrate attenuates the learning impairment induced by blockade of cholinergic muscarinic receptors in rats. Pharmacol Biochem Behav, 2004, 79, 691-699.
    • (2004) Pharmacol Biochem Behav , vol.79 , pp. 691-699
    • Devan, B.D.1    Sierra-Mercado Jr, D.2    Jimenez, M.3    BowKer, J.L.4    Duffy, K.B.5    Spangler, E.L.6    Ingram, D.K.7
  • 30
    • 33845575859 scopus 로고    scopus 로고
    • cGMP metabolism and its role in brain physiology
    • Domek-Lopacinska K, Strosznajder JB: cGMP metabolism and its role in brain physiology. J Physiol Pharmacol, 2005, 56, Suppl 2, 15-34.
    • (2005) J Physiol Pharmacol , vol.56 , Issue.SUPPL. 2 , pp. 15-34
    • Domek-Lopacinska, K.1    Strosznajder, J.B.2
  • 32
    • 0026573438 scopus 로고
    • Differential hemodynamic responses to selective inhibitors of cyclic nucleotide phosphodiesterases in conscious rats
    • Dundore RL, Habeeb PG, Pratt PF, Becker LT, Clas DM, Buchholz RA: Differential hemodynamic responses to selective inhibitors of cyclic nucleotide phosphodiesterases in conscious rats. J Cardiovasc Pharmacol, 1992, 19, 937-944.
    • (1992) J Cardiovasc Pharmacol , vol.19 , pp. 937-944
    • Dundore, R.L.1    Habeeb, P.G.2    Pratt, P.F.3    Becker, L.T.4    Clas, D.M.5    Buchholz, R.A.6
  • 33
    • 0029049804 scopus 로고
    • Continuous subcutaneous administration of the N-methyl-D-aspartic acid (NMDA) receptor antagonist ketamine in the treatment of post-herpetic neuralgia
    • Eide K, Stubhaug A, Oye I, Breivik H: Continuous subcutaneous administration of the N-methyl-D-aspartic acid (NMDA) receptor antagonist ketamine in the treatment of post-herpetic neuralgia. Pain, 1995, 61, 221-228.
    • (1995) Pain , vol.61 , pp. 221-228
    • Eide, K.1    Stubhaug, A.2    Oye, I.3    Breivik, H.4
  • 34
    • 12844262177 scopus 로고    scopus 로고
    • Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts
    • Erceg S, Monfort P, Hernandez-Viadel M, Rodrigo R, Montoliu C, Felipo V: Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts. Hepatology, 2005, 41, 299-306.
    • (2005) Hepatology , vol.41 , pp. 299-306
    • Erceg, S.1    Monfort, P.2    Hernandez-Viadel, M.3    Rodrigo, R.4    Montoliu, C.5    Felipo, V.6
  • 35
    • 33645867381 scopus 로고    scopus 로고
    • Role of extracellular cGMP and of hyperammonemia in the impairment of learning in rats with chronic hepatic failure: Therapeutic implications
    • Erceg S, Monfort P, Cauli O, Montoliu C, Llansola M, Piedrafita B, Felipo V: Role of extracellular cGMP and of hyperammonemia in the impairment of learning in rats with chronic hepatic failure: therapeutic implications. Neurochem Int, 2006, 48, 441-446.
    • (2006) Neurochem Int , vol.48 , pp. 441-446
    • Erceg, S.1    Monfort, P.2    Cauli, O.3    Montoliu, C.4    Llansola, M.5    Piedrafita, B.6    Felipo, V.7
  • 37
    • 0024317904 scopus 로고
    • Prevalence of Alzheimer's disease in a community population of older persons: Higher than previously reported
    • Evans DA, Funkenstein HH, Albert MS: Prevalence of Alzheimer's disease in a community population of older persons: higher than previously reported. JAMA, 1989, 262, 2551-2556.
    • (1989) JAMA , vol.262 , pp. 2551-2556
    • Evans, D.A.1    Funkenstein, H.H.2    Albert, M.S.3
  • 39
    • 0031783322 scopus 로고    scopus 로고
    • Regulation of sensory neuron precursor proliferation by cyclic GMP-dependent protein kinase
    • Firestein BL, Bredt DS: Regulation of sensory neuron precursor proliferation by cyclic GMP-dependent protein kinase. J Neurochem, 1998, 71, 1846-1853.
    • (1998) J Neurochem , vol.71 , pp. 1846-1853
    • Firestein, B.L.1    Bredt, D.S.2
  • 40
    • 0033988613 scopus 로고    scopus 로고
    • Painful diabetic polyneuropathy: Epidemiology, pain description, and quality of life
    • Galer BS, Gianas A, Jensen MP: Painful diabetic polyneuropathy: epidemiology, pain description, and quality of life. Diabetes Res Clin Pract, 2000, 47, 123-128.
    • (2000) Diabetes Res Clin Pract , vol.47 , pp. 123-128
    • Galer, B.S.1    Gianas, A.2    Jensen, M.P.3
  • 41
    • 33644630933 scopus 로고    scopus 로고
    • Management of neuropathic pain
    • Galluzzi KE: Management of neuropathic pain. J Am Osteopath Assoc, 2005, 105, Suppl, S12-19.
    • (2005) J Am Osteopath Assoc , vol.105 , Issue.SUPPL.
    • Galluzzi, K.E.1
  • 42
    • 0142186341 scopus 로고    scopus 로고
    • Sildenafil and transient global amnesia
    • Gandolfo C, Sugo A, Del Sette M: Sildenafil and transient global amnesia. Neurol Sci, 2003, 24, 145-146.
    • (2003) Neurol Sci , vol.24 , pp. 145-146
    • Gandolfo, C.1    Sugo, A.2    Del Sette, M.3
  • 43
    • 33747423677 scopus 로고    scopus 로고
    • Multiple sclerosis: The role of MR imaging
    • Ge Y: Multiple sclerosis: the role of MR imaging. AJNR Am J Neuroradiol, 2006, 27, 1165-1176.
    • (2006) AJNR Am J Neuroradiol , vol.27 , pp. 1165-1176
    • Ge, Y.1
  • 44
    • 33745072134 scopus 로고    scopus 로고
    • Pharmacology of acetylcholinesterase inhibitors and N-methyl-D-aspartate receptors for combination therapy in the treatment of Alzheimer's disease
    • Geerts H, Grossberg GT: Pharmacology of acetylcholinesterase inhibitors and N-methyl-D-aspartate receptors for combination therapy in the treatment of Alzheimer's disease. J Clin Pharmacol, 2006, 46, 8S-16S.
    • (2006) J Clin Pharmacol , vol.46
    • Geerts, H.1    Grossberg, G.T.2
  • 45
    • 33746584053 scopus 로고    scopus 로고
    • Sildenafil: From angina to erectile dysfunction to pulmonary hypertension and beyond
    • Ghofrani HA, Osterloh IH, Grimminger F: Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond, Nat Rev Drug Discov, 2006, 5, 689-702.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 689-702
    • Ghofrani, H.A.1    Osterloh, I.H.2    Grimminger, F.3
  • 46
    • 0037137047 scopus 로고    scopus 로고
    • Tonic-clonic seizures in patients taking sildenafil
    • Gilad R, Lampl Y, Eshel Y, Sadeh M: Tonic-clonic seizures in patients taking sildenafil. BMJ, 2002, 325, 869.
    • (2002) BMJ , vol.325 , pp. 869
    • Gilad, R.1    Lampl, Y.2    Eshel, Y.3    Sadeh, M.4
  • 47
    • 33645052699 scopus 로고    scopus 로고
    • Sildenafil citrate use and the incidence of nonarteritic anterior ischemic optic neuropathy
    • Gorkin L, Hvidsten K, Sobel RE, Siegel R: Sildenafil citrate use and the incidence of nonarteritic anterior ischemic optic neuropathy. Int J Clin Pract, 2006, 60, 500-503.
    • (2006) Int J Clin Pract , vol.60 , pp. 500-503
    • Gorkin, L.1    Hvidsten, K.2    Sobel, R.E.3    Siegel, R.4
  • 49
    • 4744351594 scopus 로고    scopus 로고
    • Influences of sildenafil on lung function and hemodynamics in patients with chronic heart failure
    • Guazzi M, Tumminello G, Di Marco F, Guazzi MD: Influences of sildenafil on lung function and hemodynamics in patients with chronic heart failure. Clin Pharmacol Ther, 2004, 76, 371-378.
    • (2004) Clin Pharmacol Ther , vol.76 , pp. 371-378
    • Guazzi, M.1    Tumminello, G.2    Di Marco, F.3    Guazzi, M.D.4
  • 50
    • 0033135538 scopus 로고    scopus 로고
    • From embryo to adult: Persistent neurogenesis and apoptotic cell death shape the lobster deutocerebrum
    • Harzsch S, Miller J, Benton J, Beltz B: From embryo to adult: persistent neurogenesis and apoptotic cell death shape the lobster deutocerebrum. J Neurosci. 1999, 19, 3472-3485.
    • (1999) J Neurosci , vol.19 , pp. 3472-3485
    • Harzsch, S.1    Miller, J.2    Benton, J.3    Beltz, B.4
  • 51
    • 14944373603 scopus 로고    scopus 로고
    • Kinetics of glutamate and gamma-aminobutyric acid in cerebrospinal fluid in a canine model of complex partial status epilepticus induced by kainic acid
    • Hasegawa D, Matsuki N, Fujita M, Ono K, Orima H: Kinetics of glutamate and gamma-aminobutyric acid in cerebrospinal fluid in a canine model of complex partial status epilepticus induced by kainic acid. J Vet Med Sci, 2004, 66, 1555-1559.
    • (2004) J Vet Med Sci , vol.66 , pp. 1555-1559
    • Hasegawa, D.1    Matsuki, N.2    Fujita, M.3    Ono, K.4    Orima, H.5
  • 52
    • 23744435642 scopus 로고    scopus 로고
    • A comparative review of the options for treatment of erectile dysfunction: Which treatment for which patient?
    • Hatzimouratidis K, Hatzichristou DG: A comparative review of the options for treatment of erectile dysfunction: which treatment for which patient? Drugs, 2005, 65, 1621-1650.
    • (2005) Drugs , vol.65 , pp. 1621-1650
    • Hatzimouratidis, K.1    Hatzichristou, D.G.2
  • 53
    • 0031772217 scopus 로고    scopus 로고
    • Nitric oxide as a retrograde messenger during long-term potentiation in hippocampus
    • Hawkins RD, Son H, Arancio O: Nitric oxide as a retrograde messenger during long-term potentiation in hippocampus. Prog Brain Res, 1998, 118, 155-172.
    • (1998) Prog Brain Res , vol.118 , pp. 155-172
    • Hawkins, R.D.1    Son, H.2    Arancio, O.3
  • 54
    • 33644877264 scopus 로고    scopus 로고
    • Erectile dysfunction drugs and non-arteritic anterior ischemic optic neuropathy: Is there a cause and effect relationship?
    • Hayreh SS: Erectile dysfunction drugs and non-arteritic anterior ischemic optic neuropathy: is there a cause and effect relationship?. J Neuroophthalmol, 2005, 25, 295-198.
    • (2005) J Neuroophthalmol , vol.25 , pp. 295-198
    • Hayreh, S.S.1
  • 55
    • 27644499337 scopus 로고    scopus 로고
    • Treatment for erectile dysfunction based on patient-reported outcomes: To every man the PDE5 inhibitor that he finds superior
    • Hedelin H, Stroberg P: Treatment for erectile dysfunction based on patient-reported outcomes: to every man the PDE5 inhibitor that he finds superior. Drugs, 2005, 65, 2245-2251.
    • (2005) Drugs , vol.65 , pp. 2245-2251
    • Hedelin, H.1    Stroberg, P.2
  • 56
    • 33645858538 scopus 로고    scopus 로고
    • Alzheimer's disease - an interactive perspective
    • Heese K, Akatsu H: Alzheimer's disease - an interactive perspective. Curr Alzheimer Res, 2006, 3, 109-121.
    • (2006) Curr Alzheimer Res , vol.3 , pp. 109-121
    • Heese, K.1    Akatsu, H.2
  • 57
    • 33644843043 scopus 로고    scopus 로고
    • An update on transient ischemic attacks
    • Hinkle J: An update on transient ischemic attacks. J Neurosci Nurs, 2005, 37, 243-248.
    • (2005) J Neurosci Nurs , vol.37 , pp. 243-248
    • Hinkle, J.1
  • 59
    • 23844554901 scopus 로고    scopus 로고
    • Past present and future: A 7-year update of Viagra ® (Sildenafil citrate)
    • Jackson G, Gillies H, Osterlo I: Past present and future: a 7-year update of Viagra ® (Sildenafil citrate). Int J Clin Pract, 2005, 59, 680-691.
    • (2005) Int J Clin Pract , vol.59 , pp. 680-691
    • Jackson, G.1    Gillies, H.2    Osterlo, I.3
  • 60
    • 2342517485 scopus 로고    scopus 로고
    • Visual short-term effects of Viagra double-blind study in healthy young subjects
    • Jagle H, Jagle C, Serey L, Yu A, Rilk A, Sadowski B, Besch D et al.: Visual short-term effects of Viagra double-blind study in healthy young subjects. Am J Ophthalmol, 2004, 137, 842-849.
    • (2004) Am J Ophthalmol , vol.137 , pp. 842-849
    • Jagle, H.1    Jagle, C.2    Serey, L.3    Yu, A.4    Rilk, A.5    Sadowski, B.6    Besch, D.7
  • 61
    • 0035800627 scopus 로고    scopus 로고
    • Sildenafil induced peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway
    • Jain NK, Patil CS, Singh A, Kulkarni SK: Sildenafil induced peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway. Brain Res, 2001, 909, 170-178.
    • (2001) Brain Res , vol.909 , pp. 170-178
    • Jain, N.K.1    Patil, C.S.2    Singh, A.3    Kulkarni, S.K.4
  • 62
    • 0037269730 scopus 로고    scopus 로고
    • Sildenafil, a phosphodiesterase-5 inhibitor, enhances the antinociceptive effect of morphine
    • Jain NK, Patil CS, Singh A, Kulkarni SK: Sildenafil, a phosphodiesterase-5 inhibitor, enhances the antinociceptive effect of morphine. Pharmacology, 2003, 67, 150-156.
    • (2003) Pharmacology , vol.67 , pp. 150-156
    • Jain, N.K.1    Patil, C.S.2    Singh, A.3    Kulkarni, S.K.4
  • 63
    • 21544467552 scopus 로고    scopus 로고
    • Cholinesterase inhibitors for patients with Alzheimer's disease: Systematic review of randomised clinical trials
    • Kaduszkiewicz H, Zimmermann T, Beck-Bornholdt HP, van den Bussche H: Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomised clinical trials. BMJ, 2005, 331, 321-327.
    • (2005) BMJ , vol.331 , pp. 321-327
    • Kaduszkiewicz, H.1    Zimmermann, T.2    Beck-Bornholdt, H.P.3    van den Bussche, H.4
  • 64
    • 33745890620 scopus 로고    scopus 로고
    • Present and future treatment strategies for pulmonary arterial hypertension: Focus on phosphodiesterase-5 inhibitors
    • Kane LB, Klings ES: Present and future treatment strategies for pulmonary arterial hypertension: focus on phosphodiesterase-5 inhibitors. Treat Respir Med, 2006, 5, 271-282.
    • (2006) Treat Respir Med , vol.5 , pp. 271-282
    • Kane, L.B.1    Klings, E.S.2
  • 65
    • 0038149079 scopus 로고    scopus 로고
    • Hippocampal cGMP-dependent protein kinase I supports an age- and protein synthesis-dependent component of long-term potentiation but is not essential for spatial reference and contextual memory
    • Kleppisch T, Wolfsgruber W, Feil S, Allmann R, Wotjak CT, Goebbels S, Nave KA et al.: Hippocampal cGMP-dependent protein kinase I supports an age- and protein synthesis-dependent component of long-term potentiation but is not essential for spatial reference and contextual memory. J Neurosci, 2003, 23, 6005-6012.
    • (2003) J Neurosci , vol.23 , pp. 6005-6012
    • Kleppisch, T.1    Wolfsgruber, W.2    Feil, S.3    Allmann, R.4    Wotjak, C.T.5    Goebbels, S.6    Nave, K.A.7
  • 66
    • 0028323167 scopus 로고
    • Subanesthetic effect of the noncompetitive NMDA antagonist, ketamine in humans. Psychotomimetic, perceptual, cognitive and neuroendocrine responses
    • Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR et al.: Subanesthetic effect of the noncompetitive NMDA antagonist, ketamine in humans. Psychotomimetic, perceptual, cognitive and neuroendocrine responses. Arch Gen Psychiatry, 1994, 51, 199-214.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 199-214
    • Krystal, J.H.1    Karper, L.P.2    Seibyl, J.P.3    Freeman, G.K.4    Delaney, R.5    Bremner, J.D.6    Heninger, G.R.7
  • 68
    • 33645731017 scopus 로고    scopus 로고
    • Ocular safety patients using sildenafil citrate therapy for erectile dysfunction
    • Laties A, Sharlip I: Ocular safety patients using sildenafil citrate therapy for erectile dysfunction. J Sex Med, 2006, 3, 12-27.
    • (2006) J Sex Med , vol.3 , pp. 12-27
    • Laties, A.1    Sharlip, I.2
  • 69
    • 0032147256 scopus 로고    scopus 로고
    • Aetiology of transient global amnesia
    • Lewis ST.: Aetiology of transient global amnesia. Lancet, 1998, 352, 1557-1558.
    • (1998) Lancet , vol.352 , pp. 1557-1558
    • Lewis, S.T.1
  • 70
    • 33644507720 scopus 로고    scopus 로고
    • Adult neurogenesis and functional plasticity in neuronal circuits
    • Lledo PM, Alonso M, Grubb MS: Adult neurogenesis and functional plasticity in neuronal circuits. Nat Rev Neurosci. 2006, 7, 179-193.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 179-193
    • Lledo, P.M.1    Alonso, M.2    Grubb, M.S.3
  • 71
    • 0028361594 scopus 로고
    • Long distance neuronal migration in the adult mammalian brain
    • Lois C, Alvarez-Buylla A: Long distance neuronal migration in the adult mammalian brain. Science, 1994, 264, 1145-1148.
    • (1994) Science , vol.264 , pp. 1145-1148
    • Lois, C.1    Alvarez-Buylla, A.2
  • 74
    • 0029050613 scopus 로고
    • Effect of ketamine, an NMDA receptor inhibitor. in acute and chronic orofacial pain
    • Mathisen LC, Skjelbred P, Skoglund LA, Oye I: Effect of ketamine, an NMDA receptor inhibitor. in acute and chronic orofacial pain. Pain, 1995, 61, 215-220.
    • (1995) Pain , vol.61 , pp. 215-220
    • Mathisen, L.C.1    Skjelbred, P.2    Skoglund, L.A.3    Oye, I.4
  • 75
    • 0036729424 scopus 로고    scopus 로고
    • Multiple combinations of co-factors produce variants of age-related cognitive decline: A theory
    • McDonald RJ: Multiple combinations of co-factors produce variants of age-related cognitive decline: a theory. Can J Exp Psychol, 2002, 56, 221-239.
    • (2002) Can J Exp Psychol , vol.56 , pp. 221-239
    • McDonald, R.J.1
  • 76
    • 0036020153 scopus 로고    scopus 로고
    • Neurologic, psychological, and aggressive disturbances with sildenafil
    • Milman HA, Arnold SB: Neurologic, psychological, and aggressive disturbances with sildenafil. Ann Pharmacother, 2002, 36, 1129-1134.
    • (2002) Ann Pharmacother , vol.36 , pp. 1129-1134
    • Milman, H.A.1    Arnold, S.B.2
  • 77
    • 4243115018 scopus 로고    scopus 로고
    • Sequential activation of soluble guanylate cyclase, protein kinase G and cGMP-degrading phosphodiesterase is necessary for proper induction of long-term potentiation in CA1 of hippocampus: Alterations in hyperammonemia
    • Monfort P, Munoz MD, Kosenko E, Llansola M, Sanchez-Perez A, Cauli O, Felipo V: Sequential activation of soluble guanylate cyclase, protein kinase G and cGMP-degrading phosphodiesterase is necessary for proper induction of long-term potentiation in CA1 of hippocampus: alterations in hyperammonemia. Neurochem Int, 2004, 45, 895-901.
    • (2004) Neurochem Int , vol.45 , pp. 895-901
    • Monfort, P.1    Munoz, M.D.2    Kosenko, E.3    Llansola, M.4    Sanchez-Perez, A.5    Cauli, O.6    Felipo, V.7
  • 78
    • 0035856423 scopus 로고    scopus 로고
    • Transient ischemic attack and stroke associated with sildenafil (Viagra) use
    • Morgan JC, Alhatou M, Oberlies J, Johnston KC: Transient ischemic attack and stroke associated with sildenafil (Viagra) use. Neurology, 2001, 57, 1730-1731.
    • (2001) Neurology , vol.57 , pp. 1730-1731
    • Morgan, J.C.1    Alhatou, M.2    Oberlies, J.3    Johnston, K.C.4
  • 79
    • 0141483436 scopus 로고    scopus 로고
    • Introduction. Erectile dysfunction and comorbid depression: Prevalence, treatment strategies, and associated medical conditions
    • Nurnberg HG: Introduction. Erectile dysfunction and comorbid depression: prevalence, treatment strategies, and associated medical conditions. J Clin Psychiatry, 2003, 64, Suppl 10, 3-4.
    • (2003) J Clin Psychiatry , vol.64 , Issue.SUPPL. 10 , pp. 3-4
    • Nurnberg, H.G.1
  • 80
    • 26244451174 scopus 로고    scopus 로고
    • Somatotopy in human primary somatosensory cortex in pain system
    • Ogino Y, Nemoto H, Goto F: Somatotopy in human primary somatosensory cortex in pain system. Anesthesiology, 2005, 103, 821-827.
    • (2005) Anesthesiology , vol.103 , pp. 821-827
    • Ogino, Y.1    Nemoto, H.2    Goto, F.3
  • 83
    • 33746381229 scopus 로고    scopus 로고
    • Modulatory effect of sildenafil in diabetes and electroconvulsive shock-induced cognitive dysfunction in rats
    • Patil CS, Singh VP, Kulkarni SK: Modulatory effect of sildenafil in diabetes and electroconvulsive shock-induced cognitive dysfunction in rats. Pharmacol Rep, 2006, 58, 373-380.
    • (2006) Pharmacol Rep , vol.58 , pp. 373-380
    • Patil, C.S.1    Singh, V.P.2    Kulkarni, S.K.3
  • 84
    • 5644304230 scopus 로고    scopus 로고
    • Modulatory effect of the PDE-5 inhibitor sildenafil in diabetic neuropathy
    • Patil CS, Singh VP, Singh S, Kulkarni SK: Modulatory effect of the PDE-5 inhibitor sildenafil in diabetic neuropathy. Pharmacology, 2004, 72, 190-195.
    • (2004) Pharmacology , vol.72 , pp. 190-195
    • Patil, C.S.1    Singh, V.P.2    Singh, S.3    Kulkarni, S.K.4
  • 85
    • 1842528383 scopus 로고    scopus 로고
    • Cholinergic-NO-cGMP mediation of sildenafil-induced antinociception
    • Patil CS, Jain NK, Singh VP, Kulkarni SK: Cholinergic-NO-cGMP mediation of sildenafil-induced antinociception. Indian J Exp Biol, 2004, 42, 361-367.
    • (2004) Indian J Exp Biol , vol.42 , pp. 361-367
    • Patil, C.S.1    Jain, N.K.2    Singh, V.P.3    Kulkarni, S.K.4
  • 86
    • 0031853996 scopus 로고    scopus 로고
    • Peripheral analgesic effects of ketamine in acute inflammatory pain
    • Pedersen JL, Galle TS, Kehlet H: Peripheral analgesic effects of ketamine in acute inflammatory pain. Anesthesiology, 1998, 89, 58-66.
    • (1998) Anesthesiology , vol.89 , pp. 58-66
    • Pedersen, J.L.1    Galle, T.S.2    Kehlet, H.3
  • 87
    • 33748375335 scopus 로고    scopus 로고
    • Neurotrophins: Mediators and modulators of pain
    • Pezet S, McMahon SB: Neurotrophins: mediators and modulators of pain. Annu Rev Neurosci, 2006, 29, 507-538.
    • (2006) Annu Rev Neurosci , vol.29 , pp. 507-538
    • Pezet, S.1    McMahon, S.B.2
  • 89
    • 33746216940 scopus 로고    scopus 로고
    • Neurogenesis in diseases of the central nervous system
    • Phillips W, Michell AW, Barker RA: Neurogenesis in diseases of the central nervous system. Stem Cells Dev, 2006, 15, 359-379.
    • (2006) Stem Cells Dev , vol.15 , pp. 359-379
    • Phillips, W.1    Michell, A.W.2    Barker, R.A.3
  • 90
    • 13644264832 scopus 로고    scopus 로고
    • Dissociable effects of acetylcholinesterase inhibitors and phosphodiesterase type 5 inhibitors on object recognition memory: Acquisition versus consolidation
    • Prickaerts J, Sik A, van der Staay FJ, de Vente J, Blokland A: Dissociable effects of acetylcholinesterase inhibitors and phosphodiesterase type 5 inhibitors on object recognition memory: acquisition versus consolidation. Psychopharmacology (Berl), 2005, 177, 381-390
    • (2005) Psychopharmacology (Berl) , vol.177 , pp. 381-390
    • Prickaerts, J.1    Sik, A.2    van der Staay, F.J.3    de Vente, J.4    Blokland, A.5
  • 92
  • 93
    • 0036468327 scopus 로고    scopus 로고
    • cGMP, but not CAMP, in rat hippocampus is involved in early stage of object memory consolidation
    • Prickaerts J, de Vente J, Honig W, Steinbusch HW, Blockland A: cGMP, but not CAMP, in rat hippocampus is involved in early stage of object memory consolidation. Eur J Pharmacol, 2002, 436, 83-87.
    • (2002) Eur J Pharmacol , vol.436 , pp. 83-87
    • Prickaerts, J.1    de Vente, J.2    Honig, W.3    Steinbusch, H.W.4    Blockland, A.5
  • 94
    • 27744508710 scopus 로고    scopus 로고
    • The efficacy and safety of PDE5 inhibitors
    • Rashid A: The efficacy and safety of PDE5 inhibitors. Clin Cornerstone, 2005, 7, 47-56.
    • (2005) Clin Cornerstone , vol.7 , pp. 47-56
    • Rashid, A.1
  • 95
    • 0031434871 scopus 로고    scopus 로고
    • Sexual dysfunction in primary medical care: Prevalence, characteristics and detection by the general practitioner
    • Read S, King M, Watson J: Sexual dysfunction in primary medical care: prevalence, characteristics and detection by the general practitioner. J Public Health Med, 1997, 19, 387-391.
    • (1997) J Public Health Med , vol.19 , pp. 387-391
    • Read, S.1    King, M.2    Watson, J.3
  • 96
    • 0038784879 scopus 로고    scopus 로고
    • Therapeutic potential of phosphodiesterase 5 inhibition for cardiovascular diease
    • Reffelmann T, Kloner RA: Therapeutic potential of phosphodiesterase 5 inhibition for cardiovascular diease. Cuculador, 2003, 108, 239-244.
    • (2003) Cuculador , vol.108 , pp. 239-244
    • Reffelmann, T.1    Kloner, R.A.2
  • 99
    • 34250789560 scopus 로고
    • A cGW-gated current control exocytosis at synapses
    • Rieke F, Schwartz EA: A cGW-gated current control exocytosis at synapses. Neuron, 1994, 13, 861-873.
    • (1994) Neuron , vol.13 , pp. 861-873
    • Rieke, F.1    Schwartz, E.A.2
  • 100
    • 0031031440 scopus 로고    scopus 로고
    • Primary pulmonary hypertension
    • Rubin LJ: Primary pulmonary hypertension. N Engl J Med, 1997, 336, 111-117.
    • (1997) N Engl J Med , vol.336 , pp. 111-117
    • Rubin, L.J.1
  • 101
    • 24344434746 scopus 로고    scopus 로고
    • The selective PDE5 inhibitor, sildenafil, improves object memory in Swiss mice and increases cGMP levels in hippocampal slices
    • Rutten K, Vente JD, Sik A, Ittersum MM, Prickaerts J, Blockland A: The selective PDE5 inhibitor, sildenafil, improves object memory in Swiss mice and increases cGMP levels in hippocampal slices. Behav Brain Res, 2005, 164, 11-16.
    • (2005) Behav Brain Res , vol.164 , pp. 11-16
    • Rutten, K.1    Vente, J.D.2    Sik, A.3    Ittersum, M.M.4    Prickaerts, J.5    Blockland, A.6
  • 103
    • 0033659804 scopus 로고    scopus 로고
    • Impoverished" and "Enriched" living conditions influence the proliferation and survival of neurons in crayfish brain
    • Sandeman RE, Sandeman DC: "Impoverished" and "Enriched" living conditions influence the proliferation and survival of neurons in crayfish brain. J Neurobiol, 2000, 45, 215-126.
    • (2000) J Neurobiol , vol.45 , pp. 215-126
    • Sandeman, R.E.1    Sandeman, D.C.2
  • 104
    • 0031456073 scopus 로고    scopus 로고
    • Cyclic-nucleotidegated Channels mediate synaptic feedback by nitric oxide
    • Savchenko A, Barnes S, Kramer RH: Cyclic-nucleotidegated Channels mediate synaptic feedback by nitric oxide. Nature, 1997, 390, 694-698.
    • (1997) Nature , vol.390 , pp. 694-698
    • Savchenko, A.1    Barnes, S.2    Kramer, R.H.3
  • 105
    • 0037056370 scopus 로고    scopus 로고
    • Transient global amenesia after sildenafil (Viagra) use
    • Savitz SA, Caplan L.R: Transient global amenesia after sildenafil (Viagra) use. Neurology, 2002, 59, 778.
    • (2002) Neurology , vol.59 , pp. 778
    • Savitz, S.A.1    Caplan, L.R.2
  • 106
    • 0035812428 scopus 로고    scopus 로고
    • Neuronal differentiation and long-term survival of newly generated cells in the olfactory mid-brain of the adult spiny lobster. Panulirus argus
    • Schmidt M: Neuronal differentiation and long-term survival of newly generated cells in the olfactory mid-brain of the adult spiny lobster. Panulirus argus. J Neurobiol, 2001, 48, 181-203.
    • (2001) J Neurobiol , vol.48 , pp. 181-203
    • Schmidt, M.1
  • 107
    • 0035257844 scopus 로고    scopus 로고
    • Central effcets of sildenafil (Viagra) on auditory selective attention and verbal recognition memory in humans: A study with event-related brain potentials
    • Schultheiss D, Muller SV, Nager W, Stief CG, Schlote N, Jonas U, Asvestis C et al.: Central effcets of sildenafil (Viagra) on auditory selective attention and verbal recognition memory in humans: a study with event-related brain potentials. World J Urol, 2001, 19, 46-50.
    • (2001) World J Urol , vol.19 , pp. 46-50
    • Schultheiss, D.1    Muller, S.V.2    Nager, W.3    Stief, C.G.4    Schlote, N.5    Jonas, U.6    Asvestis, C.7
  • 109
    • 33645982908 scopus 로고    scopus 로고
    • Management or honeymoon impotence
    • Shamloul R. Management or honeymoon impotence. J Sex Med, 2006, 3, 361-366.
    • (2006) J Sex Med , vol.3 , pp. 361-366
    • Shamloul, R.1
  • 110
    • 28444491920 scopus 로고    scopus 로고
    • The Sexual Interest and Desire Inventory-Female (SIDI-F): Item response analyses of data from women diagnosed with hypoactive sexual desire disorder
    • Sills T, Wunderlich G, Pyke R, Segraves T, Leiblum S, Clayton A, Cotton D et al.: The Sexual Interest and Desire Inventory-Female (SIDI-F): item response analyses of data from women diagnosed with hypoactive sexual desire disorder. J. Sex Med, 2005, 2, 801-818.
    • (2005) J. Sex Med , vol.2 , pp. 801-818
    • Sills, T.1    Wunderlich, G.2    Pyke, R.3    Segraves, T.4    Leiblum, S.5    Clayton, A.6    Cotton, D.7
  • 111
    • 0038034802 scopus 로고    scopus 로고
    • Sildenafil improves acquisition and retention of memory in mice
    • Singh N, Parie M: Sildenafil improves acquisition and retention of memory in mice. Indian J Physiol Pharmacol, 2003, 47, 318-324.
    • (2003) Indian J Physiol Pharmacol , vol.47 , pp. 318-324
    • Singh, N.1    Parie, M.2
  • 112
    • 31144472113 scopus 로고    scopus 로고
    • Treating erectile dysfunction by endothelial rehabilitation with phosphodiesterase 5 inhibitors
    • Sommer F, Schulze W: Treating erectile dysfunction by endothelial rehabilitation with phosphodiesterase 5 inhibitors. World J Urol, 2005, 23, 385-392
    • (2005) World J Urol , vol.23 , pp. 385-392
    • Sommer, F.1    Schulze, W.2
  • 113
    • 33745027434 scopus 로고    scopus 로고
    • The SEAR Study Group. Correlation of improved erectile function and rate of successful intercourse with improved emotional well-being assessed with the self-esteem and relationship questionnaire in men treated with sildenafil for erecitile dysfunction and stratified by age
    • Steidle CP, Stecher VJ, Pace C, Tseng LJ: The SEAR Study Group. Correlation of improved erectile function and rate of successful intercourse with improved emotional well-being assessed with the self-esteem and relationship questionnaire in men treated with sildenafil for erecitile dysfunction and stratified by age. Curr Med Res Opin, 2006, 22, 939-1448.
    • (2006) Curr Med Res Opin , vol.22 , pp. 939-1448
    • Steidle, C.P.1    Stecher, V.J.2    Pace, C.3    Tseng, L.J.4
  • 114
    • 33747178923 scopus 로고    scopus 로고
    • Glutamate enhances proliferation and neurogenesis in human neural progenitor cell cultures derived from the fetal cortex
    • Suzuki M, Nelson AD, Eickstaedt JB, Wallace K, Wright LS, Svendsen CN: Glutamate enhances proliferation and neurogenesis in human neural progenitor cell cultures derived from the fetal cortex. Eur J Neurosci, 2006, 24, 645-651.
    • (2006) Eur J Neurosci , vol.24 , pp. 645-651
    • Suzuki, M.1    Nelson, A.D.2    Eickstaedt, J.B.3    Wallace, K.4    Wright, L.S.5    Svendsen, C.N.6
  • 116
    • 33745197339 scopus 로고    scopus 로고
    • Neurogenesis in the adult central nervous system
    • Taupin P: Neurogenesis in the adult central nervous system. C R Biol, 2006, 69, 465-475.
    • (2006) C R Biol , vol.69 , pp. 465-475
    • Taupin, P.1
  • 117
    • 0037106145 scopus 로고    scopus 로고
    • Adult neurogenesis and neural stem cells of the central nervous system in mammals
    • Taupin P, Gage FH: Adult neurogenesis and neural stem cells of the central nervous system in mammals. J Neurosci Res, 2002, 69, 745-749.
    • (2002) J Neurosci Res , vol.69 , pp. 745-749
    • Taupin, P.1    Gage, F.H.2
  • 118
    • 25144480582 scopus 로고    scopus 로고
    • Botanical therapies in sexual dysfunction
    • Tharakan B, Manyam BV: Botanical therapies in sexual dysfunction. Phytother Res, 2005, 19, 457-463.
    • (2005) Phytother Res , vol.19 , pp. 457-463
    • Tharakan, B.1    Manyam, B.V.2
  • 119
    • 0032993016 scopus 로고    scopus 로고
    • Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (type 5 ) by sildenafil and related compounds
    • Turko IV, Ballard SA, Francis SH, Corbin JD: Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (type 5 ) by sildenafil and related compounds, Mol Pharmacol, 1999, 56, 124-130.
    • (1999) Mol Pharmacol , vol.56 , pp. 124-130
    • Turko, I.V.1    Ballard, S.A.2    Francis, S.H.3    Corbin, J.D.4
  • 120
    • 0033152378 scopus 로고    scopus 로고
    • Adult mammalian forebrain ependymal and Subependymal cells demonstrate proliferative Potential, but only subependymal cells have neural stem cell characteristics
    • Van der Kooy D: Adult mammalian forebrain ependymal and Subependymal cells demonstrate proliferative Potential, but only subependymal cells have neural stem cell characteristics. J Neuroci, 1999, 19, 4462-4471.
    • (1999) J Neuroci , vol.19 , pp. 4462-4471
    • Van der Kooy, D.1
  • 121
    • 0346733116 scopus 로고    scopus 로고
    • Augmentation of the NO-cGMP cascade induces anxiogenic-like effect in mice
    • Volke V, Wegener G, Vasar E: Augmentation of the NO-cGMP cascade induces anxiogenic-like effect in mice. J Naysiol Pharmacol, 2003, 54, 653-660.
    • (2003) J Naysiol Pharmacol , vol.54 , pp. 653-660
    • Volke, V.1    Wegener, G.2    Vasar, E.3
  • 122
    • 24944455102 scopus 로고    scopus 로고
    • Activation of he PI3-K Akt pathway mediates cGMP enhanced-neurogenesis in the adult progenitor cells derived from the subventricular zone
    • Wang L, Gang Zhang Z,. Lan Zhang R, Chopp M: Activation of he PI3-K Akt pathway mediates cGMP enhanced-neurogenesis in the adult progenitor cells derived from the subventricular zone. J Cerebr Blood Flow Metab, 2005, 25, 1150-1158.
    • (2005) J Cerebr Blood Flow Metab , vol.25 , pp. 1150-1158
    • Wang, L.1    Gang Zhang, Z.2    Lan Zhang, R.3    Chopp, M.4
  • 123
    • 33646118726 scopus 로고    scopus 로고
    • A decreased survival of proliferated cells in the hippocampus is associated with a decline in spatial memory in aged rats
    • Wati H, Kudo K, Qiao C, Kuroki T, Kanba S: A decreased survival of proliferated cells in the hippocampus is associated with a decline in spatial memory in aged rats. Neurosci Lett, 2006, 399, 171-174.
    • (2006) Neurosci Lett , vol.399 , pp. 171-174
    • Wati, H.1    Kudo, K.2    Qiao, C.3    Kuroki, T.4    Kanba, S.5
  • 124
    • 0031983622 scopus 로고    scopus 로고
    • Combined opioid. NMDA antagonist therapies. What advantages do they offer for the control of pain syndromes?
    • Wiesenfeld-Hallin Z: Combined opioid. NMDA antagonist therapies. What advantages do they offer for the control of pain syndromes? Drugs, 1998, 55, 1-4.
    • (1998) Drugs , vol.55 , pp. 1-4
    • Wiesenfeld-Hallin, Z.1
  • 125
    • 26244440277 scopus 로고    scopus 로고
    • Lack of the nitric oxide-cyclic GMP-potassium channel pathway for the antinociceptive effect of intrathecal zaprinast in a rat formalin test
    • Yoon MH, Chot JI, Bae HB, Jeong SW, Chung SS,. Yoo KY, Jeonq CY et al.: Lack of the nitric oxide-cyclic GMP-potassium channel pathway for the antinociceptive effect of intrathecal zaprinast in a rat formalin test. Neurosci Lett, 2005, 23, 390, 114-117.
    • (2005) Neurosci Lett , vol.23 , Issue.390 , pp. 114-117
    • Yoon, M.H.1    Chot, J.I.2    Bae, H.B.3    Jeong, S.W.4    Chung, S.S.5    Yoo, K.Y.6    Jeonq, C.Y.7
  • 126
    • 33646365892 scopus 로고    scopus 로고
    • Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia
    • Zhang RL, Zhang Z, Zhang L, Wang Y, Zhang C, Chopp M: Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia. J Neurosci Res, 2006, 83, 1213-1219.
    • (2006) J Neurosci Res , vol.83 , pp. 1213-1219
    • Zhang, R.L.1    Zhang, Z.2    Zhang, L.3    Wang, Y.4    Zhang, C.5    Chopp, M.6
  • 127
    • 16844372455 scopus 로고    scopus 로고
    • Functional recovery in aged and young rats after embolic stroke: Treatment with a phosphodiesterase type 5 inhibitor
    • Zhang L, Zhang RL, Wang Y, Zhang C, Zhang ZG, Meng H, Chopp M: Functional recovery in aged and young rats after embolic stroke: treatment with a phosphodiesterase type 5 inhibitor. Stroke, 2005, 36, 847-852.
    • (2005) Stroke , vol.36 , pp. 847-852
    • Zhang, L.1    Zhang, R.L.2    Wang, Y.3    Zhang, C.4    Zhang, Z.G.5    Meng, H.6    Chopp, M.7
  • 128
    • 0036843061 scopus 로고    scopus 로고
    • Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats
    • Zhang R, Wang Y, Zhang L, Zhang Z, Tsang W, Lu M, Zhang L et al.: Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats. Stroke, 2002, 33, 2675-2680.
    • (2002) Stroke , vol.33 , pp. 2675-2680
    • Zhang, R.1    Wang, Y.2    Zhang, L.3    Zhang, Z.4    Tsang, W.5    Lu, M.6    Zhang, L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.