Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia

Journal of Neuroscience Research

Volumn 83, Issue 7, 2006, Pages 1213-1219

  Rui, Lan Zhang ^a   Zhang, Zhenggang ^a   Zhang, Li ^a   Wang, Ying ^a   Zhang, Chunling ^a   Chopp, Michael ^a,b  

^a HENRY FORD HOSPITAL   (United States)

^b OAKLAND UNIVERSITY   (United States)

Author keywords

Aged rats; Focal cerebral ischemia; Neurogenesis; Sildenafil; Subventricular zone

Indexed keywords

DOUBLECORTIN; KI 67 ANTIGEN; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CELL PROLIFERATION; CONTROLLED STUDY; CONVALESCENCE; DRUG EFFECT; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; RAT;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; AGING; ANIMALS; BRAIN ISCHEMIA; CELL DIVISION; CELL PROLIFERATION; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; KI-67 ANTIGEN; MALE; MCM1 PROTEIN; MICROTUBULE-ASSOCIATED PROTEINS; NEURONAL PLASTICITY; NEUROPEPTIDES; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; STEM CELLS; UP-REGULATION;

EID: 33646365892     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20813     Document Type: Article

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