Phosphodiesterase inhibition by sildenafil citrate attenuates the learning impairment induced by blockade of cholinergic muscarinic receptors in rats

Pharmacology Biochemistry and Behavior

Volumn 79, Issue 4, 2004, Pages 691-699

  Devan, Bryan D ^a   Sierra Mercado Jr , Demetrio ^a   Jimenez, Mariana ^a   Bowker, Jonna L ^a   Duffy, Kara B ^a   Spangler, Edward L ^a   Ingram, Donald K ^a  

^a Gerontology Res Ctr Natl I   (United States)

Author keywords

Acetylcholine; Aging; Alzheimer's disease; Animal model; Cognitive performance; Learning and memory; Muscarinic receptors; Phosphodiesterase inhibition; Rats; Stone maze

Indexed keywords

MUSCARINIC RECEPTOR; PHOSPHODIESTERASE; SCOPOLAMINE; SILDENAFIL; SODIUM CHLORIDE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ARTICLE; ATTENUATION; BEHAVIOR; COGNITION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; ERROR; LEARNING DISORDER; MAZE TEST; MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SHOCK; STATISTICAL ANALYSIS; TASK PERFORMANCE; TRAINING;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ANIMALS; MALE; MAZE LEARNING; MUSCARINIC ANTAGONISTS; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; RATS; RATS, INBRED F344; RECEPTORS, MUSCARINIC;

ANIMALIA;

EID: 10044297395     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2004.09.019     Document Type: Article

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