The selective PDE5 inhibitor, sildenafil, improves object memory in Swiss mice and increases cGMP Levels in hippocampal slices

Behavioural Brain Research

Volumn 164, Issue 1, 2005, Pages 11-16

  Rutten, K ^a   De Vente, J ^a   Sik A ^a   Markerink Van Ittersum, M ^a   Prickaerts, J ^a   Blokland, A ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Learning and memory; Object recognition; Phosphodiesterase; Retrograde signaling; Sildenafil

Indexed keywords

CYCLIC GMP; NITRIC OXIDE DONOR; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; DRUG EFFECT; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INCUBATION TIME; MALE; MEMORY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; TASK PERFORMANCE;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ANIMALS; CYCLIC GMP; DISCRIMINATION LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FORM PERCEPTION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MEMORY; MICE; NITRIC OXIDE; PHOSPHORIC DIESTER HYDROLASES; PIPERAZINES; RECOGNITION (PSYCHOLOGY);

EID: 24344434746     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2005.04.021     Document Type: Article

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