Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats

Stroke

Volumn 33, Issue 11, 2002, Pages 2675-2680

  Zhang, Ruilan ^a   Wang, Ying ^a   Zhang, Li ^a   Zhang, Zhenggang ^a   Tsang, Wayne ^a   Lu, Mei ^a   Zhang, Lijie ^a   Chopp, Michael ^a  

^a HENRY FORD HOSPITAL   (United States)

Author keywords

Neurogenesis; Rats; Recovery of function; Sildenafil; Stroke, cardioembolic

Indexed keywords

BROXURIDINE; CYCLIC GMP; MESSENGER RNA; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; SILDENAFIL;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CONVALESCENCE; DENTATE GYRUS; DRUG EFFECT; FUNCTIONAL ASSESSMENT; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVOUS SYSTEM DEVELOPMENT; NERVOUS SYSTEM FUNCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STROKE;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; BROMODEOXYURIDINE; CELL COUNT; CELL DIVISION; CEREBROVASCULAR ACCIDENT; CEREBROVASCULAR CIRCULATION; CORPUS STRIATUM; CYCLIC GMP; DENTATE GYRUS; DISEASE MODELS, ANIMAL; LATERAL VENTRICLES; MALE; NERVE REGENERATION; NEURONS; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; RNA, MESSENGER; TREATMENT OUTCOME;

EID: 0036843061     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000034399.95249.59     Document Type: Article

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