메뉴 건너뛰기




Volumn 26, Issue 25, 2007, Pages 3745-3757

Targeting death-inducing receptors in cancer therapy

Author keywords

Anti tumor immune response; Apoptosis; DR4; DR5; TNF superfamily; TRAIL

Indexed keywords

ANTINEOPLASTIC AGENT; BORTEZOMIB; CD137 LIGAND MONOCLONAL ANTIBODY; CD40 LIGAND MONOCLONAL ANTIBODY; CETUXIMAB; CYTOKINE ANTIBODY; DEATH RECEPTOR 4; DEATH RECEPTOR 4 MONOCLONAL ANTIBODY; DEATH RECEPTOR 5; DEATH RECEPTOR 5 MONOCLONAL ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR 2 MONOCLONAL ANTIBODY; INTERFERON; MD5 1; PROTEASOME INHIBITOR; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; RITUXIMAB; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

EID: 34249663310     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210374     Document Type: Review
Times cited : (174)

References (131)
  • 1
    • 0037442125 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
    • Akiyama K, Ebihara S, Yada A, Matsumura K, Aiba S, Nukiwa T et al. (2003). Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. J Immunol 170: 1641-1648.
    • (2003) J Immunol , vol.170 , pp. 1641-1648
    • Akiyama, K.1    Ebihara, S.2    Yada, A.3    Matsumura, K.4    Aiba, S.5    Nukiwa, T.6
  • 2
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
    • Albert ML, Sauter B, Bhardwaj N. (1998). Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392: 86-89.
    • (1998) Nature , vol.392 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2    Bhardwaj, N.3
  • 3
    • 0141925950 scopus 로고    scopus 로고
    • Drug interactions between the proteasome inhibitor bortezomib and cytotoxic chemotherapy, tumor necrosis factor (TNF) α, and TNF-related apoptosis-inducing ligand in prostate cancer
    • An J, Sun YP, Adams J, Fisher M, Belldegrun A, Rettig MB. (2003). Drug interactions between the proteasome inhibitor bortezomib and cytotoxic chemotherapy, tumor necrosis factor (TNF) α, and TNF-related apoptosis-inducing ligand in prostate cancer. Clin Cancer Res 9: 4537-4545.
    • (2003) Clin Cancer Res , vol.9 , pp. 4537-4545
    • An, J.1    Sun, Y.P.2    Adams, J.3    Fisher, M.4    Belldegrun, A.5    Rettig, M.B.6
  • 4
    • 0036598992 scopus 로고    scopus 로고
    • Targeting death and decoy receptors of the tumour-necrosis factor superfamily
    • Ashkenazi A. (2002). Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat Rev Cancer 2: 420-430.
    • (2002) Nat Rev Cancer , vol.2 , pp. 420-430
    • Ashkenazi, A.1
  • 5
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A, Dixit VM. (1998). Death receptors: signaling and modulation. Science 281: 1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 7
    • 0014864304 scopus 로고
    • Search for common antigenicities among twenty-five sarcomas induced by methylcholanthrene
    • Basombrio MA. (1970). Search for common antigenicities among twenty-five sarcomas induced by methylcholanthrene. Cancer Res 30: 2458-2462.
    • (1970) Cancer Res , vol.30 , pp. 2458-2462
    • Basombrio, M.A.1
  • 8
    • 18744401119 scopus 로고    scopus 로고
    • Monoclonal antibodies targeting the epidermal growth factor receptor
    • Bianco R, Daniele G, Ciardiello F, Tortora G. (2005). Monoclonal antibodies targeting the epidermal growth factor receptor. Curr Drug Targets 6: 275-287.
    • (2005) Curr Drug Targets , vol.6 , pp. 275-287
    • Bianco, R.1    Daniele, G.2    Ciardiello, F.3    Tortora, G.4
  • 9
    • 0141679399 scopus 로고    scopus 로고
    • Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model
    • Buchsbaum DJ, Zhou T, Grizzle WE, Oliver PG, Hammond CJ, Zhang S et al. (2003). Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model. Clin Cancer Res 9: 3731-3741.
    • (2003) Clin Cancer Res , vol.9 , pp. 3731-3741
    • Buchsbaum, D.J.1    Zhou, T.2    Grizzle, W.E.3    Oliver, P.G.4    Hammond, C.J.5    Zhang, S.6
  • 10
    • 32844455274 scopus 로고    scopus 로고
    • APO2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in prostate cancer therapy
    • Bucur O, Ray S, Bucur MC, Almasan A. (2006). APO2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in prostate cancer therapy. Front Biosci 11: 1549-1568.
    • (2006) Front Biosci , vol.11 , pp. 1549-1568
    • Bucur, O.1    Ray, S.2    Bucur, M.C.3    Almasan, A.4
  • 12
    • 0037100434 scopus 로고    scopus 로고
    • Apoptosis and interferons: Role of interferonstimulated genes as mediators of apoptosis
    • Chawla-Sarkar M, Leaman DW, Jacobs BS, Borden EC. (2002). Apoptosis and interferons: role of interferonstimulated genes as mediators of apoptosis. J Immunol 169: 847-855.
    • (2002) J Immunol , vol.169 , pp. 847-855
    • Chawla-Sarkar, M.1    Leaman, D.W.2    Jacobs, B.S.3    Borden, E.C.4
  • 14
    • 0034652156 scopus 로고    scopus 로고
    • Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy
    • Chinnaiyan AM, Prasad U, Shankar S, Hamstra DA, Shanaiah M, Chenevert TL et al. (2000). Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc Natl Acad Sci USA 97: 1754-1759.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1754-1759
    • Chinnaiyan, A.M.1    Prasad, U.2    Shankar, S.3    Hamstra, D.A.4    Shanaiah, M.5    Chenevert, T.L.6
  • 15
    • 0035871757 scopus 로고    scopus 로고
    • Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4
    • Chuntharapai A, Dodge K, Grimmer K, Schroeder K, Marsters SA, Koeppen H et al. (2001). Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4. J Immunol 166: 4891-4898.
    • (2001) J Immunol , vol.166 , pp. 4891-4898
    • Chuntharapai, A.1    Dodge, K.2    Grimmer, K.3    Schroeder, K.4    Marsters, S.A.5    Koeppen, H.6
  • 16
    • 29144496895 scopus 로고    scopus 로고
    • Preligand assembly domainmediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis
    • Clancy L, Mruk K, Archer K, Woelfel M, Mongkolsapaya J, Screaton G et al. (2005). Preligand assembly domainmediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis. Proc Natl Acad Sci USA 102: 18099-18104.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18099-18104
    • Clancy, L.1    Mruk, K.2    Archer, K.3    Woelfel, M.4    Mongkolsapaya, J.5    Screaton, G.6
  • 17
    • 4143116932 scopus 로고    scopus 로고
    • Tumor suppressor IRF-1 mediated retinoid and interferon anticancer signaling to death ligand TRAIL
    • Clarke N, Jimenez-Lara AM, Voltz E, Gronemeyer H. (2004). Tumor suppressor IRF-1 mediated retinoid and interferon anticancer signaling to death ligand TRAIL. EMBO J 23: 3051-3060.
    • (2004) EMBO J , vol.23 , pp. 3051-3060
    • Clarke, N.1    Jimenez-Lara, A.M.2    Voltz, E.3    Gronemeyer, H.4
  • 19
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
    • Clynes RA, Towers TL, Presta LG, Ravetch JV. (2000). Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets. Nat Med 6: 443-446.
    • (2000) Nat Med , vol.6 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4
  • 21
    • 0024203368 scopus 로고
    • A phase I clinical trial of recombinant human tumor necrosis factor
    • Creagan ET, Kovach JS, Moertel CG, Frytak S, Kvols LK. (1988). A phase I clinical trial of recombinant human tumor necrosis factor. Cancer 62: 2467-2471.
    • (1988) Cancer , vol.62 , pp. 2467-2471
    • Creagan, E.T.1    Kovach, J.S.2    Moertel, C.G.3    Frytak, S.4    Kvols, L.K.5
  • 23
    • 0036467427 scopus 로고    scopus 로고
    • Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
    • Cretney E, Takeda K, Yagita H, Glaccum M, Peschon JJ, Smyth MJ. (2002). Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J Immunol 168: 1356-1361.
    • (2002) J Immunol , vol.168 , pp. 1356-1361
    • Cretney, E.1    Takeda, K.2    Yagita, H.3    Glaccum, M.4    Peschon, J.J.5    Smyth, M.J.6
  • 24
    • 0141609073 scopus 로고    scopus 로고
    • Co-stimulatory members of the TNFR family: Keys to effective T-cell immunity?
    • Croft M. (2003a). Co-stimulatory members of the TNFR family: keys to effective T-cell immunity? Nat Rev Immunol 3: 609-620.
    • (2003) Nat Rev Immunol , vol.3 , pp. 609-620
    • Croft, M.1
  • 25
    • 0038658898 scopus 로고    scopus 로고
    • Costimulation of T cells by OX40, 4-1BB, and CD27
    • Croft M. (2003b). Costimulation of T cells by OX40, 4-1BB, and CD27. Cytokine Growth Factor Rev 14: 265-273.
    • (2003) Cytokine Growth Factor Rev , vol.14 , pp. 265-273
    • Croft, M.1
  • 26
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial NN, Korsmeyer SJ. (2004). Cell death: critical control points. Cell 116: 205-219.
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 28
    • 0036031772 scopus 로고    scopus 로고
    • Therapeutics targeting signal transduction for patients with colorectal carcinoma
    • de Bono JS, Rowinsky EK. (2002). Therapeutics targeting signal transduction for patients with colorectal carcinoma. Br Med Bull 64: 227-254.
    • (2002) Br Med Bull , vol.64 , pp. 227-254
    • de Bono, J.S.1    Rowinsky, E.K.2
  • 29
    • 0032942436 scopus 로고    scopus 로고
    • To die or not to die -the quest of the TRAIL receptors
    • Degli-Esposti M. (1999). To die or not to die -the quest of the TRAIL receptors. J Leukoc Biol 65: 535-542.
    • (1999) J Leukoc Biol , vol.65 , pp. 535-542
    • Degli-Esposti, M.1
  • 30
    • 0037033448 scopus 로고    scopus 로고
    • Antitumor monoclonal antibodies enhance crosspresentation of cellular antigens and the generation of myeloma-specific killer T cells by dendritic cells
    • Dhodapkar KM, Krasovsky J, Williamson B, Dhodapkar MV. (2002). Antitumor monoclonal antibodies enhance crosspresentation of cellular antigens and the generation of myeloma-specific killer T cells by dendritic cells. J Exp Med 195: 125-133.
    • (2002) J Exp Med , vol.195 , pp. 125-133
    • Dhodapkar, K.M.1    Krasovsky, J.2    Williamson, B.3    Dhodapkar, M.V.4
  • 31
    • 10344260656 scopus 로고    scopus 로고
    • TRAIL-R as a negative regulator of innate immune cell responses
    • Diehl GE, Yue HH, Hsieh K, Kuang AA, Ho M, Morici LA et al. (2004). TRAIL-R as a negative regulator of innate immune cell responses. Immunity 21: 877-889.
    • (2004) Immunity , vol.21 , pp. 877-889
    • Diehl, G.E.1    Yue, H.H.2    Hsieh, K.3    Kuang, A.A.4    Ho, M.5    Morici, L.A.6
  • 32
    • 0032984496 scopus 로고    scopus 로고
    • Diehl L, den Boer AT, Schoenberger SP, van der Voort EI, Schumacher TN, Melief CJ et al. (1999). CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy. Nat Med 5: 774-779.
    • Diehl L, den Boer AT, Schoenberger SP, van der Voort EI, Schumacher TN, Melief CJ et al. (1999). CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy. Nat Med 5: 774-779.
  • 33
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn GP, Old LJ, Schreiber RD. (2004). The immunobiology of cancer immunosurveillance and immunoediting. Immunity 21: 137-148.
    • (2004) Immunity , vol.21 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 34
    • 0036301503 scopus 로고    scopus 로고
    • CTLA-4: New insights into its biological function and use in tumor immunotherapy
    • Egen JG, Kuhns MS, Allison JP. (2002). CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat Immunol 3: 611-618.
    • (2002) Nat Immunol , vol.3 , pp. 611-618
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 35
    • 0032896709 scopus 로고    scopus 로고
    • CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help
    • French RR, Chan HT, Tutt AL, Glennie MJ. (1999). CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help. Nat Med 5: 548-553.
    • (1999) Nat Med , vol.5 , pp. 548-553
    • French, R.R.1    Chan, H.T.2    Tutt, A.L.3    Glennie, M.J.4
  • 36
    • 84889271499 scopus 로고    scopus 로고
    • IFNγ sensitizes for apoptosis by upregulating caspase-8 expression through the stat1 pathway
    • Fulda S, Debatin KM. (2002). IFNγ sensitizes for apoptosis by upregulating caspase-8 expression through the stat1 pathway. Oncogene 21: 2295-2308.
    • (2002) Oncogene , vol.21 , pp. 2295-2308
    • Fulda, S.1    Debatin, K.M.2
  • 37
    • 0036341291 scopus 로고    scopus 로고
    • Smac agonists sensitize for Apo2L/TRAIL- or anticancer druginduced apoptosis and induce regression of malignant glioma in vivo
    • Fulda S, Wick W, Weller M, Debatin KM. (2002). Smac agonists sensitize for Apo2L/TRAIL- or anticancer druginduced apoptosis and induce regression of malignant glioma in vivo. Nat Med 8: 808-815.
    • (2002) Nat Med , vol.8 , pp. 808-815
    • Fulda, S.1    Wick, W.2    Weller, M.3    Debatin, K.M.4
  • 38
    • 0036199305 scopus 로고    scopus 로고
    • Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells
    • Futagawa T, Akiba H, Kodama T, Takeda K, Hosoda Y, Yagita H et al. (2002). Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells. Int Immunol 14: 275-286.
    • (2002) Int Immunol , vol.14 , pp. 275-286
    • Futagawa, T.1    Akiba, H.2    Kodama, T.3    Takeda, K.4    Hosoda, Y.5    Yagita, H.6
  • 40
    • 24144489702 scopus 로고    scopus 로고
    • Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL
    • Ganten TM, Koschny R, Haas TL, Sykora J, Li-Weber M, Herzer K et al. (2005). Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL. Hepatology 42: 588-597.
    • (2005) Hepatology , vol.42 , pp. 588-597
    • Ganten, T.M.1    Koschny, R.2    Haas, T.L.3    Sykora, J.4    Li-Weber, M.5    Herzer, K.6
  • 42
    • 24944458177 scopus 로고    scopus 로고
    • Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: Induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death
    • Georgakis GV, Li Y, Humphreys R, Andreeff M, O'Brien S, Younes M et al. (2005). Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death. Br J Haematol 130: 501-510.
    • (2005) Br J Haematol , vol.130 , pp. 501-510
    • Georgakis, G.V.1    Li, Y.2    Humphreys, R.3    Andreeff, M.4    O'Brien, S.5    Younes, M.6
  • 43
    • 0033572413 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11
    • Gliniak B, Le T. (1999). Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11. Cancer Res 59: 6153-6158.
    • (1999) Cancer Res , vol.59 , pp. 6153-6158
    • Gliniak, B.1    Le, T.2
  • 45
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. (2000). The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 46
    • 9244237679 scopus 로고    scopus 로고
    • TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice
    • Hao C, Song JH, Hsi B, Lewis J, Song DK, Petruk KC et al. (2004). TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res 64: 8502-8506.
    • (2004) Cancer Res , vol.64 , pp. 8502-8506
    • Hao, C.1    Song, J.H.2    Hsi, B.3    Lewis, J.4    Song, D.K.5    Petruk, K.C.6
  • 47
    • 0347364696 scopus 로고    scopus 로고
    • NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy
    • Hayakawa Y, Screpanti V, Yagita H, Grandien A, Ljunggren HG, Smyth MJ et al. (2004). NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy. J Immunol 172: 123-129.
    • (2004) J Immunol , vol.172 , pp. 123-129
    • Hayakawa, Y.1    Screpanti, V.2    Yagita, H.3    Grandien, A.4    Ljunggren, H.G.5    Smyth, M.J.6
  • 48
    • 0025792319 scopus 로고
    • Phase II studies of recombinant human tumor necrosis factor α in patients with malignant disease: A summary of the southwest oncology group experience
    • Hersh EM, Metch BS, Muggia FM, Brown TD, Whitehead RP, Budd GT et al. (1991). Phase II studies of recombinant human tumor necrosis factor α in patients with malignant disease: a summary of the southwest oncology group experience. J Immunother 10: 426-431.
    • (1991) J Immunother , vol.10 , pp. 426-431
    • Hersh, E.M.1    Metch, B.S.2    Muggia, F.M.3    Brown, T.D.4    Whitehead, R.P.5    Budd, G.T.6
  • 49
    • 0036827808 scopus 로고    scopus 로고
    • Cholestasis increases tumor necrosis factor-related apoptosisinducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicity
    • Higuchi H, Bronk SF, Taniai M, Canbay A, Gores GJ. (2002). Cholestasis increases tumor necrosis factor-related apoptosisinducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicity. J Pharmacol Exp Ther 303: 461-467.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 461-467
    • Higuchi, H.1    Bronk, S.F.2    Taniai, M.3    Canbay, A.4    Gores, G.J.5
  • 50
    • 4544357718 scopus 로고    scopus 로고
    • Monoclonal antibodies as effective therapeutic agents for solid tumors
    • Hinoda Y, Sasaki S, Ishida T, Imai K. (2004). Monoclonal antibodies as effective therapeutic agents for solid tumors. Cancer Sci 95: 621-625.
    • (2004) Cancer Sci , vol.95 , pp. 621-625
    • Hinoda, Y.1    Sasaki, S.2    Ishida, T.3    Imai, K.4
  • 51
    • 17944376030 scopus 로고    scopus 로고
    • Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity
    • Ichikawa K, Liu W, Zhao L, Wang Z, Liu D, Ohtsuka T et al. (2001). Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat Med 7: 954-960.
    • (2001) Nat Med , vol.7 , pp. 954-960
    • Ichikawa, K.1    Liu, W.2    Zhao, L.3    Wang, Z.4    Liu, D.5    Ohtsuka, T.6
  • 52
    • 0027281373 scopus 로고
    • A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen
    • Itoh N, Nagata S. (1993). A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen. J Biol Chem 268: 10932-10937.
    • (1993) J Biol Chem , vol.268 , pp. 10932-10937
    • Itoh, N.1    Nagata, S.2
  • 53
    • 0042329166 scopus 로고    scopus 로고
    • Hepatitis B virus enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity by increasing TRAIL-R1/death receptor 4 expression
    • Janssen HL, Higuchi H, Abdulkarim A, Gores GJ. (2003). Hepatitis B virus enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity by increasing TRAIL-R1/death receptor 4 expression. J Hepatol 39: 414-420.
    • (2003) J Hepatol , vol.39 , pp. 414-420
    • Janssen, H.L.1    Higuchi, H.2    Abdulkarim, A.3    Gores, G.J.4
  • 54
    • 0034022160 scopus 로고    scopus 로고
    • Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
    • Jo M, Kim TH, Seol DW, Esplen JE, Dorko K, Billiar TR et al. (2000). Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med 6: 564-567.
    • (2000) Nat Med , vol.6 , pp. 564-567
    • Jo, M.1    Kim, T.H.2    Seol, D.W.3    Esplen, J.E.4    Dorko, K.5    Billiar, T.R.6
  • 55
    • 0037169358 scopus 로고    scopus 로고
    • Apoptosis: A link between cancer genetics and chemotherapy
    • Johnstone RW, Ruefli AA, Lowe SW. (2002). Apoptosis: a link between cancer genetics and chemotherapy. Cell 108: 153-164.
    • (2002) Cell , vol.108 , pp. 153-164
    • Johnstone, R.W.1    Ruefli, A.A.2    Lowe, S.W.3
  • 56
    • 28544439923 scopus 로고    scopus 로고
    • On the TRAIL of a new therapy for leukemia
    • Kaufmann SH, Steensma DP. (2005). On the TRAIL of a new therapy for leukemia. Leukemia 19: 2195-2202.
    • (2005) Leukemia , vol.19 , pp. 2195-2202
    • Kaufmann, S.H.1    Steensma, D.P.2
  • 57
    • 3342894130 scopus 로고    scopus 로고
    • Targeting death receptors in cancer with Apo2L/TRAIL
    • Kelley SK, Ashkenazi A. (2004). Targeting death receptors in cancer with Apo2L/TRAIL. Curr Opin Pharmacol 4: 333-339.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 333-339
    • Kelley, S.K.1    Ashkenazi, A.2
  • 58
    • 0036852191 scopus 로고    scopus 로고
    • Natural selection of tumor variants in the generation of 'tumor escape' phenotypes
    • Khong HT, Restifo NP. (2002). Natural selection of tumor variants in the generation of 'tumor escape' phenotypes. Nat Immunol 3: 999-1005.
    • (2002) Nat Immunol , vol.3 , pp. 999-1005
    • Khong, H.T.1    Restifo, N.P.2
  • 59
    • 0033974084 scopus 로고    scopus 로고
    • Molecular determinants of response to TRAIL in killing of normal and cancer cells
    • Kim K, Fisher MJ, Xu SQ, el-Deiry WS. (2000). Molecular determinants of response to TRAIL in killing of normal and cancer cells. Clin Cancer Res 6: 335-346.
    • (2000) Clin Cancer Res , vol.6 , pp. 335-346
    • Kim, K.1    Fisher, M.J.2    Xu, S.Q.3    el-Deiry, W.S.4
  • 60
    • 0036272615 scopus 로고    scopus 로고
    • Tumor-targeted gene delivery: An attractive strategy to use highly active effector molecules in cancer treatment
    • Kircheis R, Wightman L, Kursa M, Ostermann E, Wagner E. (2002). Tumor-targeted gene delivery: an attractive strategy to use highly active effector molecules in cancer treatment. Gene Therapy 9: 731-735.
    • (2002) Gene Therapy , vol.9 , pp. 731-735
    • Kircheis, R.1    Wightman, L.2    Kursa, M.3    Ostermann, E.4    Wagner, E.5
  • 61
    • 33644802666 scopus 로고    scopus 로고
    • Efficient TRAIL-R1/DR4-mediated apoptosis in melanoma cells by tumor necrosis factor-related apoptosisinducing ligand (TRAIL)
    • Kurbanov BM, Geilen CC, Fecker LF, Orfanos CE, Eberle J. (2005). Efficient TRAIL-R1/DR4-mediated apoptosis in melanoma cells by tumor necrosis factor-related apoptosisinducing ligand (TRAIL). J Invest Dermatol 125: 1010-1019.
    • (2005) J Invest Dermatol , vol.125 , pp. 1010-1019
    • Kurbanov, B.M.1    Geilen, C.C.2    Fecker, L.F.3    Orfanos, C.E.4    Eberle, J.5
  • 63
    • 0036131142 scopus 로고    scopus 로고
    • Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog bax
    • LeBlanc H, Lawrence D, Varfolomeev E, Totpal K, Morlan J, Schow P et al. (2002). Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog bax. Nat Med 8: 274-281.
    • (2002) Nat Med , vol.8 , pp. 274-281
    • LeBlanc, H.1    Lawrence, D.2    Varfolomeev, E.3    Totpal, K.4    Morlan, J.5    Schow, P.6
  • 64
    • 0037273848 scopus 로고    scopus 로고
    • Apo2L/TRAIL and its death and decoy receptors
    • LeBlanc HN, Ashkenazi A. (2003). Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ 10: 66-75.
    • (2003) Cell Death Differ , vol.10 , pp. 66-75
    • LeBlanc, H.N.1    Ashkenazi, A.2
  • 65
    • 4344718859 scopus 로고    scopus 로고
    • 4-1BB and OX40 dual costimulation synergistically stimulate primary specific CD8 T cells for robust effector function
    • Lee SJ, Myers L, Muralimohan G, Dai J, Qiao Y, Li Z et al. (2004). 4-1BB and OX40 dual costimulation synergistically stimulate primary specific CD8 T cells for robust effector function. J Immunol 173: 3002-3012.
    • (2004) J Immunol , vol.173 , pp. 3002-3012
    • Lee, S.J.1    Myers, L.2    Muralimohan, G.3    Dai, J.4    Qiao, Y.5    Li, Z.6
  • 66
    • 0034307531 scopus 로고    scopus 로고
    • Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand-mediated apoptosis
    • Leverkus M, Walczak H, McLellan A, Fries HW, Terbeck G, Brocker EB et al. (2000). Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand-mediated apoptosis. Blood 96: 2628-2631.
    • (2000) Blood , vol.96 , pp. 2628-2631
    • Leverkus, M.1    Walczak, H.2    McLellan, A.3    Fries, H.W.4    Terbeck, G.5    Brocker, E.B.6
  • 67
    • 4444243683 scopus 로고    scopus 로고
    • A small molecule Smac mimic potentiates TRAIL- and TNFa-mediated cell death
    • Li L, Thomas RM, Suzuki H, De Brabander JK, Wang X, Harran PG. (2004). A small molecule Smac mimic potentiates TRAIL- and TNFa-mediated cell death. Science 305: 1471-1474.
    • (2004) Science , vol.305 , pp. 1471-1474
    • Li, L.1    Thomas, R.M.2    Suzuki, H.3    De Brabander, J.K.4    Wang, X.5    Harran, P.G.6
  • 68
    • 33747829837 scopus 로고    scopus 로고
    • Combined treatment of colorectal tumours with agonistic TRAIL receptor antibodies HGS-ETR1 and HGS-ETR2 and radiotherapy: Enhanced effects in vitro and dose-dependent growth delay in vivo
    • Marini P, Denzinger S, Schiller D, Kauder S, Welz S, Humphreys R et al. (2006). Combined treatment of colorectal tumours with agonistic TRAIL receptor antibodies HGS-ETR1 and HGS-ETR2 and radiotherapy: enhanced effects in vitro and dose-dependent growth delay in vivo. Oncogene 25: 5145-5154.
    • (2006) Oncogene , vol.25 , pp. 5145-5154
    • Marini, P.1    Denzinger, S.2    Schiller, D.3    Kauder, S.4    Welz, S.5    Humphreys, R.6
  • 69
    • 0032535119 scopus 로고    scopus 로고
    • NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies
    • Melero I, Johnston JV, Shufford WW, Mittler RS, Chen L. (1998). NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell Immunol 190: 167-172.
    • (1998) Cell Immunol , vol.190 , pp. 167-172
    • Melero, I.1    Johnston, J.V.2    Shufford, W.W.3    Mittler, R.S.4    Chen, L.5
  • 70
    • 0031007143 scopus 로고    scopus 로고
    • Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
    • Melero I, Shuford WW, Newby SA, Aruffo A, Ledbetter JA, Hellstrom KE et al. (1997). Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nat Med 3: 682-685.
    • (1997) Nat Med , vol.3 , pp. 682-685
    • Melero, I.1    Shuford, W.W.2    Newby, S.A.3    Aruffo, A.4    Ledbetter, J.A.5    Hellstrom, K.E.6
  • 71
    • 8544224305 scopus 로고    scopus 로고
    • Interferon γ enhances the effectiveness of tumor necrosis factor-related apoptosis-inducing ligand receptor agonists in a xenograft model of Ewing's sarcoma
    • Merchant MS, Yang X, Melchionda F, Romero M, Klein R, Thiele CJ et al. (2004). Interferon γ enhances the effectiveness of tumor necrosis factor-related apoptosis-inducing ligand receptor agonists in a xenograft model of Ewing's sarcoma. Cancer Res 64: 8349-8356.
    • (2004) Cancer Res , vol.64 , pp. 8349-8356
    • Merchant, M.S.1    Yang, X.2    Melchionda, F.3    Romero, M.4    Klein, R.5    Thiele, C.J.6
  • 72
    • 0035437171 scopus 로고    scopus 로고
    • TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: Therapeutic applications
    • Mitsiades CS, Treon SP, Mitsiades N, Shima Y, Richardson P, Schlossman R et al. (2001). TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications. Blood 98: 795-804.
    • (2001) Blood , vol.98 , pp. 795-804
    • Mitsiades, C.S.1    Treon, S.P.2    Mitsiades, N.3    Shima, Y.4    Richardson, P.5    Schlossman, R.6
  • 73
    • 0742272016 scopus 로고    scopus 로고
    • Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2
    • Mori E, Thomas M, Motoki K, Nakazawa K, Tahara T, Tomizuka K et al. (2004). Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2. Cell Death Differ 11: 203-207.
    • (2004) Cell Death Differ , vol.11 , pp. 203-207
    • Mori, E.1    Thomas, M.2    Motoki, K.3    Nakazawa, K.4    Tahara, T.5    Tomizuka, K.6
  • 74
    • 20244378961 scopus 로고    scopus 로고
    • Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2
    • Motoki K, Mori E, Matsumoto A, Thomas M, Tomura T, Humphreys R et al. (2005). Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2. Clin Cancer Res 11: 3126-3135.
    • (2005) Clin Cancer Res , vol.11 , pp. 3126-3135
    • Motoki, K.1    Mori, E.2    Matsumoto, A.3    Thomas, M.4    Tomura, T.5    Humphreys, R.6
  • 76
    • 27444433031 scopus 로고    scopus 로고
    • Tumour necrosis factor related apoptosis inducing ligand (TRAIL) induces hepatic steatosis in viral hepatitis and after alcohol intake
    • Mundt B, Wirth T, Zender L, Waltemathe M, Trautwein C, Manns MP et al. (2005). Tumour necrosis factor related apoptosis inducing ligand (TRAIL) induces hepatic steatosis in viral hepatitis and after alcohol intake. Gut 54: 1590-1596.
    • (2005) Gut , vol.54 , pp. 1590-1596
    • Mundt, B.1    Wirth, T.2    Zender, L.3    Waltemathe, M.4    Trautwein, C.5    Manns, M.P.6
  • 77
    • 0034641932 scopus 로고    scopus 로고
    • From bench to clinic with apoptosisbased therapeutic agents
    • Nicholson DW. (2000). From bench to clinic with apoptosisbased therapeutic agents. Nature 407: 810-816.
    • (2000) Nature , vol.407 , pp. 810-816
    • Nicholson, D.W.1
  • 80
    • 0037417134 scopus 로고    scopus 로고
    • Synergistic induction of tumor cell apoptosis by death receptor antibody and chemotherapy agent through JNK/p38 and mitochondrial death pathway
    • Ohtsuka T, Buchsbaum D, Oliver P, Makhija S, Kimberly R, Zhou T. (2003). Synergistic induction of tumor cell apoptosis by death receptor antibody and chemotherapy agent through JNK/p38 and mitochondrial death pathway. Oncogene 22: 2034-2044.
    • (2003) Oncogene , vol.22 , pp. 2034-2044
    • Ohtsuka, T.1    Buchsbaum, D.2    Oliver, P.3    Makhija, S.4    Kimberly, R.5    Zhou, T.6
  • 81
    • 10844219883 scopus 로고    scopus 로고
    • Role of tumor necrosis factor-related apoptosis-inducing ligand in interferoninduced apoptosis in human bladder cancer cells
    • Papageorgiou A, Lashinger L, Millikan R, Grossman HB, Benedict W, Dinney CP et al. (2004). Role of tumor necrosis factor-related apoptosis-inducing ligand in interferoninduced apoptosis in human bladder cancer cells. Cancer Res 64: 8973-8979.
    • (2004) Cancer Res , vol.64 , pp. 8973-8979
    • Papageorgiou, A.1    Lashinger, L.2    Millikan, R.3    Grossman, H.B.4    Benedict, W.5    Dinney, C.P.6
  • 82
    • 4644293572 scopus 로고    scopus 로고
    • Cancer immunotherapy: Breaking the barriers to harvest the crop
    • Pardoll D, Allison J. (2004). Cancer immunotherapy: breaking the barriers to harvest the crop. Nat Med 10: 887-892.
    • (2004) Nat Med , vol.10 , pp. 887-892
    • Pardoll, D.1    Allison, J.2
  • 83
    • 0031903646 scopus 로고    scopus 로고
    • Phase II study of receptorenhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
    • Pegram MD, Lipton A, Hayes DF, Weber BL, Baselga JM, Tripathy D et al. (1998). Phase II study of receptorenhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol 16: 2659-2671.
    • (1998) J Clin Oncol , vol.16 , pp. 2659-2671
    • Pegram, M.D.1    Lipton, A.2    Hayes, D.F.3    Weber, B.L.4    Baselga, J.M.5    Tripathy, D.6
  • 84
    • 17544367410 scopus 로고    scopus 로고
    • Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
    • Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A. (1996). Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 271: 12687-12690.
    • (1996) J Biol Chem , vol.271 , pp. 12687-12690
    • Pitti, R.M.1    Marsters, S.A.2    Ruppert, S.3    Donahue, C.J.4    Moore, A.5    Ashkenazi, A.6
  • 85
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW. (2004). Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 4: 71-78.
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 87
    • 21044441651 scopus 로고    scopus 로고
    • HGS-ETR1, a fully human TRAILreceptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo
    • Pukac L, Kanakaraj P, Humphreys R, Alderson R, Bloom M, Sung C et al. (2005). HGS-ETR1, a fully human TRAILreceptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo. Br J Cancer 92: 1430-1441.
    • (2005) Br J Cancer , vol.92 , pp. 1430-1441
    • Pukac, L.1    Kanakaraj, P.2    Humphreys, R.3    Alderson, R.4    Bloom, M.5    Sung, C.6
  • 88
    • 0034923333 scopus 로고    scopus 로고
    • Modulating the immune response with dendritic cells and their growth factors
    • Pulendran B, Banchereau J, Maraskovsky E, Maliszewski C. (2001). Modulating the immune response with dendritic cells and their growth factors. Trends Immunol 22: 41-47.
    • (2001) Trends Immunol , vol.22 , pp. 41-47
    • Pulendran, B.1    Banchereau, J.2    Maraskovsky, E.3    Maliszewski, C.4
  • 89
    • 0035044296 scopus 로고    scopus 로고
    • Avoiding premature apoptosis of normal epidermal cells
    • Qin J, Chaturvedi V, Bonish B, Nickoloff BJ. (2001). Avoiding premature apoptosis of normal epidermal cells. Nat Med 7: 385-386.
    • (2001) Nat Med , vol.7 , pp. 385-386
    • Qin, J.1    Chaturvedi, V.2    Bonish, B.3    Nickoloff, B.J.4
  • 90
    • 0036307752 scopus 로고    scopus 로고
    • Immune complex-mediated antigen presentation induces tumor immunity
    • Rafiq K, Bergtold A, Clynes R. (2002). Immune complex-mediated antigen presentation induces tumor immunity. J Clin Invest 110: 71-79.
    • (2002) J Clin Invest , vol.110 , pp. 71-79
    • Rafiq, K.1    Bergtold, A.2    Clynes, R.3
  • 91
    • 0036175547 scopus 로고    scopus 로고
    • Modulating apoptosis pathways in low-grade B-cell malignancies using biological response modifiers
    • Reed JC, Kitada S, Kim Y, Byrd J. (2002). Modulating apoptosis pathways in low-grade B-cell malignancies using biological response modifiers. Semin Oncol 29: 10-24.
    • (2002) Semin Oncol , vol.29 , pp. 10-24
    • Reed, J.C.1    Kitada, S.2    Kim, Y.3    Byrd, J.4
  • 92
    • 33644832724 scopus 로고    scopus 로고
    • Targeted induction of apoptosis in cancer management: The emerging role of tumor necrosis factor-related apoptosis-inducing ligand receptor activating agents
    • Rowinsky EK. (2005). Targeted induction of apoptosis in cancer management: the emerging role of tumor necrosis factor-related apoptosis-inducing ligand receptor activating agents. J Clin Oncol 23: 9394-9407.
    • (2005) J Clin Oncol , vol.23 , pp. 9394-9407
    • Rowinsky, E.K.1
  • 93
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS, Brandt R, Ciardiello F, Normanno N. (1995). Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19: 183-232.
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 94
    • 28944449421 scopus 로고    scopus 로고
    • Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy
    • Sayers TJ, Murphy WJ. (2006). Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy. Cancer Immunol Immunother 55: 76-84.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 76-84
    • Sayers, T.J.1    Murphy, W.J.2
  • 95
    • 0034536743 scopus 로고    scopus 로고
    • Regulation of death receptor-mediated apoptosis pathways
    • Schmitz I, Kirchhoff S, Krammer PH. (2000). Regulation of death receptor-mediated apoptosis pathways. Int J Biochem Cell Biol 32: 1123-1136.
    • (2000) Int J Biochem Cell Biol , vol.32 , pp. 1123-1136
    • Schmitz, I.1    Kirchhoff, S.2    Krammer, P.H.3
  • 96
    • 0038751850 scopus 로고    scopus 로고
    • Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL)
    • Schneider P, Olson D, Tardivel A, Browning B, Lugovskoy A, Gong D et al. (2003). Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL). J Biol Chem 278: 5444-5454.
    • (2003) J Biol Chem , vol.278 , pp. 5444-5454
    • Schneider, P.1    Olson, D.2    Tardivel, A.3    Browning, B.4    Lugovskoy, A.5    Gong, D.6
  • 98
    • 2942565827 scopus 로고    scopus 로고
    • Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: Mechanisms and clinical implications
    • Shankar S, Srivastava RK. (2004). Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications. Drug Resist Updat 7: 139-156.
    • (2004) Drug Resist Updat , vol.7 , pp. 139-156
    • Shankar, S.1    Srivastava, R.K.2
  • 99
    • 0032522463 scopus 로고    scopus 로고
    • p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor α
    • Sheikh MS, Burns TF, Huang Y, Wu GS, Amundson S, Brooks KS et al. (1998). p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor α. Cancer Res 58: 1593-1598.
    • (1998) Cancer Res , vol.58 , pp. 1593-1598
    • Sheikh, M.S.1    Burns, T.F.2    Huang, Y.3    Wu, G.S.4    Amundson, S.5    Brooks, K.S.6
  • 100
  • 102
    • 0642312825 scopus 로고    scopus 로고
    • Rituximab (monoclonal anti-CD20 antibody): Mechanisms of action and resistance
    • Smith MR. (2003). Rituximab (monoclonal anti-CD20 antibody): mechanisms of action and resistance. Oncogene 22: 7359-7368.
    • (2003) Oncogene , vol.22 , pp. 7359-7368
    • Smith, M.R.1
  • 103
  • 105
    • 0032984347 scopus 로고    scopus 로고
    • Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40
    • Sotomayor EM, Borrello I, Tubb E, Rattis FM, Bien H, Lu Z et al. (1999). Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40. Nat Med 5: 780-787.
    • (1999) Nat Med , vol.5 , pp. 780-787
    • Sotomayor, E.M.1    Borrello, I.2    Tubb, E.3    Rattis, F.M.4    Bien, H.5    Lu, Z.6
  • 106
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H. (1995). Mechanisms and genes of cellular suicide. Science 267: 1445-1449.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 107
    • 0033137063 scopus 로고    scopus 로고
    • 4-1BB is a bona fide CD8 T cell survival signal
    • Takahashi C, Mittler RS, Vella AT. (1999). 4-1BB is a bona fide CD8 T cell survival signal. J Immunol 162: 5037-5040.
    • (1999) J Immunol , vol.162 , pp. 5037-5040
    • Takahashi, C.1    Mittler, R.S.2    Vella, A.T.3
  • 108
    • 0037148518 scopus 로고    scopus 로고
    • Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development
    • Takeda K, Smyth MJ, Cretney E, Hayakawa Y, Kayagaki N, Yagita H et al. (2002). Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development. J Exp Med 195: 161-169.
    • (2002) J Exp Med , vol.195 , pp. 161-169
    • Takeda, K.1    Smyth, M.J.2    Cretney, E.3    Hayakawa, Y.4    Kayagaki, N.5    Yagita, H.6
  • 109
  • 110
    • 0034732258 scopus 로고    scopus 로고
    • Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site
    • Takimoto R, El-Deiry WS. (2000). Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site. Oncogene 19: 1735-1743.
    • (2000) Oncogene , vol.19 , pp. 1735-1743
    • Takimoto, R.1    El-Deiry, W.S.2
  • 111
    • 0027275490 scopus 로고
    • A novel domain within the 55 kd TNF receptor signals cell death
    • Tartaglia LA, Ayres TM, Wong GH, Goeddel DV. (1993). A novel domain within the 55 kd TNF receptor signals cell death. Cell 74: 845-853.
    • (1993) Cell , vol.74 , pp. 845-853
    • Tartaglia, L.A.1    Ayres, T.M.2    Wong, G.H.3    Goeddel, D.V.4
  • 112
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson CB. (1995). Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 113
    • 0036153928 scopus 로고    scopus 로고
    • Fas receptormediated apoptosis: A clinical application?
    • Timmer T, de Vries EG, de Jong S. (2002). Fas receptormediated apoptosis: a clinical application? J Pathol 196: 125-134.
    • (2002) J Pathol , vol.196 , pp. 125-134
    • Timmer, T.1    de Vries, E.G.2    de Jong, S.3
  • 114
    • 18444417703 scopus 로고    scopus 로고
    • Redundant and alternative roles for activating fc receptors and complement in an antibodydependent model of autoimmune vitiligo
    • Trcka J, Moroi Y, Clynes RA, Goldberg SM, Bergtold A, Perales MA et al. (2002). Redundant and alternative roles for activating fc receptors and complement in an antibodydependent model of autoimmune vitiligo. Immunity 16: 861-868.
    • (2002) Immunity , vol.16 , pp. 861-868
    • Trcka, J.1    Moroi, Y.2    Clynes, R.A.3    Goldberg, S.M.4    Bergtold, A.5    Perales, M.A.6
  • 115
    • 0034725664 scopus 로고    scopus 로고
    • Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor
    • Truneh A, Sharma S, Silverman C, Khandekar S, Reddy MP, Deen KC et al. (2000). Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor. J Biol Chem 275: 23319-23325.
    • (2000) J Biol Chem , vol.275 , pp. 23319-23325
    • Truneh, A.1    Sharma, S.2    Silverman, C.3    Khandekar, S.4    Reddy, M.P.5    Deen, K.C.6
  • 116
    • 33744987907 scopus 로고    scopus 로고
    • Eradication of established tumors in mice by a combination antibody-based therapy
    • Uno T, Takeda K, Kojima Y, Yoshizawa H, Akiba H, Mittler RS et al. (2006). Eradication of established tumors in mice by a combination antibody-based therapy. Nat Med 12: 693-698.
    • (2006) Nat Med , vol.12 , pp. 693-698
    • Uno, T.1    Takeda, K.2    Kojima, Y.3    Yoshizawa, H.4    Akiba, H.5    Mittler, R.S.6
  • 117
    • 0042121068 scopus 로고    scopus 로고
    • Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines
    • van Geelen CM, de Vries EG, Le TK, van Weeghel RP, de Jong S. (2003). Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines. Br J Cancer 89: 363-373.
    • (2003) Br J Cancer , vol.89 , pp. 363-373
    • van Geelen, C.M.1    de Vries, E.G.2    Le, T.K.3    van Weeghel, R.P.4    de Jong, S.5
  • 118
    • 0035947569 scopus 로고    scopus 로고
    • Interferon-γ sensitizes human myeloid leukemia cells to death receptor-mediated apoptosis by a pleiotropic mechanism
    • Varela N, Munoz-Pinedo C, Ruiz-Ruiz C, Robledo G, Pedroso M, Lopez-Rivas A. (2001). Interferon-γ sensitizes human myeloid leukemia cells to death receptor-mediated apoptosis by a pleiotropic mechanism. J Biol Chem 276: 17779-17787.
    • (2001) J Biol Chem , vol.276 , pp. 17779-17787
    • Varela, N.1    Munoz-Pinedo, C.2    Ruiz-Ruiz, C.3    Robledo, G.4    Pedroso, M.5    Lopez-Rivas, A.6
  • 119
    • 0026717674 scopus 로고
    • The pathophysiology of tumor necrosis factors
    • Vassalli P. (1992). The pathophysiology of tumor necrosis factors. Annu Rev Immunol 10: 411-452.
    • (1992) Annu Rev Immunol , vol.10 , pp. 411-452
    • Vassalli, P.1
  • 120
    • 0642275474 scopus 로고    scopus 로고
    • An antibody against DR4 (TRAIL-R1) in combination with doxorubicin selectively kills malignant but not normal prostate cells
    • Voelkel-Johnson C. (2003). An antibody against DR4 (TRAIL-R1) in combination with doxorubicin selectively kills malignant but not normal prostate cells. Cancer Biol Ther 2: 283-290.
    • (2003) Cancer Biol Ther , vol.2 , pp. 283-290
    • Voelkel-Johnson, C.1
  • 121
    • 0036792685 scopus 로고    scopus 로고
    • TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy
    • Wajant H, Pfizenmaier K, Scheurich P. (2002). TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy. Apoptosis 7: 449-459.
    • (2002) Apoptosis , vol.7 , pp. 449-459
    • Wajant, H.1    Pfizenmaier, K.2    Scheurich, P.3
  • 122
    • 0032929520 scopus 로고    scopus 로고
    • Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
    • Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M et al. (1999). Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 5: 157-163.
    • (1999) Nat Med , vol.5 , pp. 157-163
    • Walczak, H.1    Miller, R.E.2    Ariail, K.3    Gliniak, B.4    Griffith, T.S.5    Kubin, M.6
  • 124
    • 17644389199 scopus 로고    scopus 로고
    • TNF/TNFR family members in costimulation of T cell responses
    • Watts TH. (2005). TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol 23: 23-68.
    • (2005) Annu Rev Immunol , vol.23 , pp. 23-68
    • Watts, T.H.1
  • 125
    • 0036195860 scopus 로고    scopus 로고
    • Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors
    • Wilcox RA, Flies DB, Zhu G, Johnson AJ, Tamada K, Chapoval AI et al. (2002). Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors. J Clin Invest 109: 651-659.
    • (2002) J Clin Invest , vol.109 , pp. 651-659
    • Wilcox, R.A.1    Flies, D.B.2    Zhu, G.3    Johnson, A.J.4    Tamada, K.5    Chapoval, A.I.6
  • 126
    • 13344285339 scopus 로고
    • Identification and characterization of a new member of the TNF family that induces apoptosis
    • Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK et al. (1995). Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3: 673-682.
    • (1995) Immunity , vol.3 , pp. 673-682
    • Wiley, S.R.1    Schooley, K.2    Smolak, P.J.3    Din, W.S.4    Huang, C.P.5    Nicholl, J.K.6
  • 128
    • 33646403907 scopus 로고    scopus 로고
    • Monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) induces apoptosis in primary renal cell carcinoma cells in vitro and inhibits tumor growth in vivo
    • Zeng Y, Wu XX, Fiscella M, Shimada O, Humphreys R, Albert V et al. (2006). Monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) induces apoptosis in primary renal cell carcinoma cells in vitro and inhibits tumor growth in vivo. Int J Oncol 28: 421-430.
    • (2006) Int J Oncol , vol.28 , pp. 421-430
    • Zeng, Y.1    Wu, X.X.2    Fiscella, M.3    Shimada, O.4    Humphreys, R.5    Albert, V.6
  • 129
    • 4143122387 scopus 로고    scopus 로고
    • Activating Fc receptors are required for antitumor efficacy of the antibodies directed toward CD25 in a murine model of adult T-cell leukemia
    • Zhang M, Zhang Z, Garmestani K, Goldman CK, Ravetch JV, Brechbiel MW et al. (2004). Activating Fc receptors are required for antitumor efficacy of the antibodies directed toward CD25 in a murine model of adult T-cell leukemia. Cancer Res 64: 5825-5829.
    • (2004) Cancer Res , vol.64 , pp. 5825-5829
    • Zhang, M.1    Zhang, Z.2    Garmestani, K.3    Goldman, C.K.4    Ravetch, J.V.5    Brechbiel, M.W.6
  • 130
    • 0013583837 scopus 로고    scopus 로고
    • Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
    • Zhang XD, Franco A, Myers K, Gray C, Nguyen T, Hersey P. (1999). Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res 59: 2747-2753.
    • (1999) Cancer Res , vol.59 , pp. 2747-2753
    • Zhang, X.D.1    Franco, A.2    Myers, K.3    Gray, C.4    Nguyen, T.5    Hersey, P.6
  • 131
    • 0037089544 scopus 로고    scopus 로고
    • Antihuman epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab enhances cytolytic activity of class I-restricted HER2-specific T lymphocytes against HER2-overexpressing tumor cells
    • zum Buschenfelde CM, Hermann C, Schmidt B, Peschel C, Bernhard H. (2002). Antihuman epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab enhances cytolytic activity of class I-restricted HER2-specific T lymphocytes against HER2-overexpressing tumor cells. Cancer Res 62: 2244-2247.
    • (2002) Cancer Res , vol.62 , pp. 2244-2247
    • zum Buschenfelde, C.M.1    Hermann, C.2    Schmidt, B.3    Peschel, C.4    Bernhard, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.