Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

Nature Medicine

Volumn 3, Issue 6, 1997, Pages 682-685

  Melero, Ignacio ^a   Shuford, Walter W ^a   Newby, Stephanie Ashe ^a   Aruffo, Alejandro ^a   Ledbetter, Jeffrey A ^a   Hellström, Karl Erik ^a   Mittler, Robert S ^a   Chen, Lieping ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GLYCOPROTEIN; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; B LYMPHOCYTE ACTIVATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOTHERAPY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD137; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; MAST-CELL SARCOMA; MICE; MICE, INBRED C3H; MICE, INBRED DBA; NEOPLASM TRANSPLANTATION; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR; SARCOMA, EXPERIMENTAL; T-LYMPHOCYTES, CYTOTOXIC; TUMOR CELLS, CULTURED;

EID: 0031007143     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0697-682     Document Type: Article

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