메뉴 건너뛰기




Volumn 15, Issue 6, 2007, Pages 1053-1064

Advances in preclinical investigation of prostate cancer gene therapy

Author keywords

[No Author keywords available]

Indexed keywords

5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; CG 7870; CONDITIONALLY REPLICATING ADENOVIRUS; CV 706; CV 787; CYTOSINE DEAMINASE; DENDRITIC CELL VACCINE; DEPSIPEPTIDE; DOCETAXEL; FAS LIGAND; FLUTAMIDE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR VACCINE; HEAT SHOCK PROTEIN 70; INTERLEUKIN 24; KALLIKREIN; NITROREDUCTASE; ONCOLYTIC ADENOVIRUS; ONYX 015; OSTEOCALCIN; PACLITAXEL; PROBASIN; PROSTATE SPECIFIC ANTIGEN; PROSTATE SPECIFIC MEMBRANE ANTIGEN; PROTEIN P53; TUMOR CELL VACCINE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN RECEPTOR 2; VITAMIN D;

EID: 34249315474     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/sj.mt.6300181     Document Type: Review
Times cited : (18)

References (148)
  • 1
    • 34249316043 scopus 로고    scopus 로고
    • National Cancer Institute, D, Surveillance Research Program, Cancer Statistics Branch (released April 2005, based on the November 2004 submission). Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER Stat Database: Incidence - SEER 9 Regs Public-Use, Nov 2004 Sub (1973-2002).
    • National Cancer Institute, D, Surveillance Research Program, Cancer Statistics Branch (released April 2005, based on the November 2004 submission). Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER Stat Database: Incidence - SEER 9 Regs Public-Use, Nov 2004 Sub (1973-2002).
  • 2
    • 34249298919 scopus 로고    scopus 로고
    • Genetic Modification Clinical Research Information System, M.C.R.I.S. .
    • Genetic Modification Clinical Research Information System, M.C.R.I.S. .
  • 3
    • 0025160687 scopus 로고
    • Species- and organ-specificity of secretory proteins derived from human prostate and seminal vesicles
    • Aumuller, G, Seitz, J, Lilja, H, Abrahamsson, PA, von der Kammer, H and Scheit, KH (1990). Species- and organ-specificity of secretory proteins derived from human prostate and seminal vesicles. Prostate 17 31-40.
    • (1990) Prostate , vol.17 , pp. 31-40
    • Aumuller, G.1    Seitz, J.2    Lilja, H.3    Abrahamsson, P.A.4    von der Kammer, H.5    Scheit, K.H.6
  • 4
    • 0029865240 scopus 로고    scopus 로고
    • Two androgen response regions cooperate in steroid hormone regulated activity of the prostate-specific antigen promoter
    • Cleutjens, KB, van Eekelen, CC, van der Korput, HA, Brinkmann, AO and Trapman, J (1996). Two androgen response regions cooperate in steroid hormone regulated activity of the prostate-specific antigen promoter. J Biol Chem 271: 6379-6388.
    • (1996) J Biol Chem , vol.271 , pp. 6379-6388
    • Cleutjens, K.B.1    van Eekelen, C.C.2    van der Korput, H.A.3    Brinkmann, A.O.4    Trapman, J.5
  • 5
    • 0033520426 scopus 로고    scopus 로고
    • Cooperative assembly of androgen receptor into a nucleoprotein complex that regulates the prostate-specific antigen enhancer
    • Huang, W, Shostak, Y, Tarr, P, Sawyers, C and Carey, M (1999). Cooperative assembly of androgen receptor into a nucleoprotein complex that regulates the prostate-specific antigen enhancer. J Biol Chem 274: 25756-25768.
    • (1999) J Biol Chem , vol.274 , pp. 25756-25768
    • Huang, W.1    Shostak, Y.2    Tarr, P.3    Sawyers, C.4    Carey, M.5
  • 6
    • 0034834392 scopus 로고    scopus 로고
    • Chimeric PSA enhancers exhibit augmented activity in prostate cancer gene therapy vectors
    • Wu, L, Matherly, J, Smallwood, A, Adams, JY, Billick, E, Belldegrun, A et al. (2001). Chimeric PSA enhancers exhibit augmented activity in prostate cancer gene therapy vectors. Gene Ther 8: 1416-1426.
    • (2001) Gene Ther , vol.8 , pp. 1416-1426
    • Wu, L.1    Matherly, J.2    Smallwood, A.3    Adams, J.Y.4    Billick, E.5    Belldegrun, A.6
  • 7
    • 0036192826 scopus 로고    scopus 로고
    • Molecular engineering of a two-step transcription amplification (TSTA) system for transgene delivery in prostate cancer
    • Zhang, L, Adams, JY, Billick, E, Ilagan, R, Iyer, M, Le, K et al. (2002). Molecular engineering of a two-step transcription amplification (TSTA) system for transgene delivery in prostate cancer. Mol Ther 5: 223-232.
    • (2002) Mol Ther , vol.5 , pp. 223-232
    • Zhang, L.1    Adams, J.Y.2    Billick, E.3    Ilagan, R.4    Iyer, M.5    Le, K.6
  • 8
    • 0034715538 scopus 로고    scopus 로고
    • An androgen response element mediates LNCaP cell dependent androgen induction of the hK2 gene
    • Mitchell, SH, Murtha, PE, Zhang, S, Zhu, W and Young, CY (2000). An androgen response element mediates LNCaP cell dependent androgen induction of the hK2 gene. Mol Cell Endocrinol 168: 89-99.
    • (2000) Mol Cell Endocrinol , vol.168 , pp. 89-99
    • Mitchell, S.H.1    Murtha, P.E.2    Zhang, S.3    Zhu, W.4    Young, C.Y.5
  • 9
    • 0033119603 scopus 로고    scopus 로고
    • Identification of the transcriptional regulatory sequences of human kallikrein 2 and their use in the construction of calydon virus 764, an attenuated replication competent adenovirus for prostate cancer therapy
    • Yu, DC, Sakamoto, GT and Henderson, DR (1999). Identification of the transcriptional regulatory sequences of human kallikrein 2 and their use in the construction of calydon virus 764, an attenuated replication competent adenovirus for prostate cancer therapy. Cancer Res 59 1498-1504.
    • (1999) Cancer Res , vol.59 , pp. 1498-1504
    • Yu, D.C.1    Sakamoto, G.T.2    Henderson, D.R.3
  • 10
    • 0035937310 scopus 로고    scopus 로고
    • Robust prostate-specific expression for targeted gene therapy based on the human kallikrein 2 promoter
    • Xie, X, Zhao, X, Liu, Y, Young, CY, Tindall, DJ, Slawin, KM et al. (2001). Robust prostate-specific expression for targeted gene therapy based on the human kallikrein 2 promoter. Hum Gene Ther 12: 549-561.
    • (2001) Hum Gene Ther , vol.12 , pp. 549-561
    • Xie, X.1    Zhao, X.2    Liu, Y.3    Young, C.Y.4    Tindall, D.J.5    Slawin, K.M.6
  • 11
    • 0036562226 scopus 로고    scopus 로고
    • Expanded human tissue kallikrein family - a novel panel of cancer biomarkers
    • Yousef, GM and Diamandis, EP (2002). Expanded human tissue kallikrein family - a novel panel of cancer biomarkers. Tumour Biol 23: 185-192.
    • (2002) Tumour Biol , vol.23 , pp. 185-192
    • Yousef, G.M.1    Diamandis, E.P.2
  • 12
    • 0027960980 scopus 로고
    • Cooperative binding of androgen receptors to two DNA sequences is required for androgen induction of the probasin gene
    • Kasper, S, Rennie, PS, Bruchovsky, N, Sheppard, PC, Cheng, H, Lin, L et al. (1994). Cooperative binding of androgen receptors to two DNA sequences is required for androgen induction of the probasin gene. J Biol Chem 269: 31763-31769.
    • (1994) J Biol Chem , vol.269 , pp. 31763-31769
    • Kasper, S.1    Rennie, P.S.2    Bruchovsky, N.3    Sheppard, P.C.4    Cheng, H.5    Lin, L.6
  • 13
    • 0034214052 scopus 로고    scopus 로고
    • Prostatic neoplasia in transgenic mice with prostate-directed overexpression of the c-myc oncoprotein
    • Zhang, X, Lee, C, Ng, PY, Rubin, M, Shabsigh, A and Buttyan, R (2000). Prostatic neoplasia in transgenic mice with prostate-directed overexpression of the c-myc oncoprotein. Prostate 43: 278-285.
    • (2000) Prostate , vol.43 , pp. 278-285
    • Zhang, X.1    Lee, C.2    Ng, P.Y.3    Rubin, M.4    Shabsigh, A.5    Buttyan, R.6
  • 14
    • 0034650401 scopus 로고    scopus 로고
    • Prostate-specific antigen promoter/enhancer driven gene therapy for prostate cancer: Construction and testing of a tissue-specific adenovirus vector
    • Latham, JP, Searle, PF, Mautner, V and James, ND (2000). Prostate-specific antigen promoter/enhancer driven gene therapy for prostate cancer: Construction and testing of a tissue-specific adenovirus vector. Cancer Res 60 334-341.
    • (2000) Cancer Res , vol.60 , pp. 334-341
    • Latham, J.P.1    Searle, P.F.2    Mautner, V.3    James, N.D.4
  • 15
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman, BJ and Feldman, D (2001). The development of androgen-independent prostate cancer. Nat Rev Cancer 1: 34-45.
    • (2001) Nat Rev Cancer , vol.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 16
    • 18844413765 scopus 로고    scopus 로고
    • Functionality of androgen receptor-based gene expression imaging in hormone refractory prostate cancer
    • Sato, M, Johnson, M, Zhang, L, Gambhir, SS, Carey, M and Wu, L (2005). Functionality of androgen receptor-based gene expression imaging in hormone refractory prostate cancer. Clin Cancer Res 11: 3743-3749.
    • (2005) Clin Cancer Res , vol.11 , pp. 3743-3749
    • Sato, M.1    Johnson, M.2    Zhang, L.3    Gambhir, S.S.4    Carey, M.5    Wu, L.6
  • 17
    • 0037169539 scopus 로고    scopus 로고
    • Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells
    • Yeung, F, Law, WK, Yeh, CH, Westendorf, JJ, Zhang, Y, Wang, R et al. (2002). Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells. J Biol Chem 277: 2468-2476.
    • (2002) J Biol Chem , vol.277 , pp. 2468-2476
    • Yeung, F.1    Law, W.K.2    Yeh, C.H.3    Westendorf, J.J.4    Zhang, Y.5    Wang, R.6
  • 18
    • 0030981187 scopus 로고    scopus 로고
    • Prostate-specific membrane antigen
    • Fair, WR, Israeli, RS and Heston, WD (1997). Prostate-specific membrane antigen. Prostate 32: 140-148.
    • (1997) Prostate , vol.32 , pp. 140-148
    • Fair, W.R.1    Israeli, R.S.2    Heston, W.D.3
  • 19
    • 10344234761 scopus 로고    scopus 로고
    • Molecular insights into prostate cancer progression: The missing link of tumor microenvironment
    • Chung, LW, Baseman, A, Assikis, V and Zhau, HE (2005). Molecular insights into prostate cancer progression: The missing link of tumor microenvironment. J Urol 173: 10-20.
    • (2005) J Urol , vol.173 , pp. 10-20
    • Chung, L.W.1    Baseman, A.2    Assikis, V.3    Zhau, H.E.4
  • 20
    • 0033153362 scopus 로고    scopus 로고
    • Osteomimetic properties of prostate cancer cells: A hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment
    • Koeneman, KS, Yeung, F and Chung, LW (1999). Osteomimetic properties of prostate cancer cells: A hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment. Prostate 39: 246-261.
    • (1999) Prostate , vol.39 , pp. 246-261
    • Koeneman, K.S.1    Yeung, F.2    Chung, L.W.3
  • 21
    • 0032611052 scopus 로고    scopus 로고
    • Regulated expression of the bone-specific osteocalcin gene by vitamins and hormones
    • Lian, JB, Stein, GS, Stein, JL and van Wijnen, AJ (1999). Regulated expression of the bone-specific osteocalcin gene by vitamins and hormones. Vitam Horm 55: 443-509.
    • (1999) Vitam Horm , vol.55 , pp. 443-509
    • Lian, J.B.1    Stein, G.S.2    Stein, J.L.3    van Wijnen, A.J.4
  • 22
    • 0036606008 scopus 로고    scopus 로고
    • A novel targeting modality to enhance adenoviral replication by vitamin D(3) in androgen-independent human prostate cancer cells and tumors
    • Hsieh, CL, Yang, L, Miao, L, Yeung, F, Kao, C, Yang, H et al. (2002). A novel targeting modality to enhance adenoviral replication by vitamin D(3) in androgen-independent human prostate cancer cells and tumors. Cancer Res 62: 3084-3092.
    • (2002) Cancer Res , vol.62 , pp. 3084-3092
    • Hsieh, C.L.1    Yang, L.2    Miao, L.3    Yeung, F.4    Kao, C.5    Yang, H.6
  • 23
    • 16844364795 scopus 로고    scopus 로고
    • Human osteocalcin and bone sialoprotein mediating osteomimicry of prostate cancer cells: Role of cAMP-dependent protein kinase A signaling pathway
    • Huang, WC, Xie, Z, Konaka, H, Sodek, J, Zhau, HE and Chung LW (2005). Human osteocalcin and bone sialoprotein mediating osteomimicry of prostate cancer cells: Role of cAMP-dependent protein kinase A signaling pathway. Cancer Res 65: 2303-2313.
    • (2005) Cancer Res , vol.65 , pp. 2303-2313
    • Huang, W.C.1    Xie, Z.2    Konaka, H.3    Sodek, J.4    Zhau, H.E.5    Chung, L.W.6
  • 24
    • 0025875889 scopus 로고
    • Acceleration of human prostate cancer growth in vivo by factors produced by prostate and bone fibroblasts
    • Gleave, M, Hsieh, JT, Gao, CA, von Eschenbach, AC and Chung LW (1991). Acceleration of human prostate cancer growth in vivo by factors produced by prostate and bone fibroblasts. Cancer Res 51: 3753-3761.
    • (1991) Cancer Res , vol.51 , pp. 3753-3761
    • Gleave, M.1    Hsieh, J.T.2    Gao, C.A.3    von Eschenbach, A.C.4    Chung, L.W.5
  • 25
    • 0032915758 scopus 로고    scopus 로고
    • Osteoblast conditioned media contain TGF-β1 and modulate the migration of prostate tumor cells and their interactions with extracellular matrix components
    • Festuccia, C, Bologna, M, Gravina, GL, Guerra, F, Angelucci, A, Villanova, I et al. (1999). Osteoblast conditioned media contain TGF-β1 and modulate the migration of prostate tumor cells and their interactions with extracellular matrix components. Int J Cancer 81: 395-403.
    • (1999) Int J Cancer , vol.81 , pp. 395-403
    • Festuccia, C.1    Bologna, M.2    Gravina, G.L.3    Guerra, F.4    Angelucci, A.5    Villanova, I.6
  • 26
    • 0028321891 scopus 로고
    • Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: Role of bone stromal cells
    • Wu, HC, Hsieh, JT, Gleave, ME, Brown, NM, Pathak, S and Chung, LW (1994). Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: Role of bone stromal cells. Int J Cancer 57: 406-412.
    • (1994) Int J Cancer , vol.57 , pp. 406-412
    • Wu, H.C.1    Hsieh, J.T.2    Gleave, M.E.3    Brown, N.M.4    Pathak, S.5    Chung, L.W.6
  • 27
    • 0028272478 scopus 로고
    • Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer
    • Thalmann, GN, Anezinis, PE, Chang, SM, Zhau, HE, Kim, EE, Hopwood, VL et al. (1994). Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer. Cancer Res 54: 2577-2581.
    • (1994) Cancer Res , vol.54 , pp. 2577-2581
    • Thalmann, G.N.1    Anezinis, P.E.2    Chang, S.M.3    Zhau, H.E.4    Kim, E.E.5    Hopwood, V.L.6
  • 28
    • 0029025319 scopus 로고
    • The role of stromal-epithelial interaction in normal and malignant growth
    • Chung, LW (1995). The role of stromal-epithelial interaction in normal and malignant growth. Cancer Surv 23: 33-42.
    • (1995) Cancer Surv , vol.23 , pp. 33-42
    • Chung, L.W.1
  • 29
    • 0035003457 scopus 로고    scopus 로고
    • Permanent phenotypic and genotypic changes of prostate cancer cells cultured in a three-dimensional rotating-wall vessel
    • Rhee, HW, Zhau, HE, Pathak, S, Multani, AS, Pennanen, S, Visakorpi, T et al. (2001). Permanent phenotypic and genotypic changes of prostate cancer cells cultured in a three-dimensional rotating-wall vessel. In Vitro Cell Dev Biol Anim 37: 127-140.
    • (2001) In Vitro Cell Dev Biol Anim , vol.37 , pp. 127-140
    • Rhee, H.W.1    Zhau, H.E.2    Pathak, S.3    Multani, A.S.4    Pennanen, S.5    Visakorpi, T.6
  • 30
    • 0034168328 scopus 로고    scopus 로고
    • Osteocalcin-directed gene therapy for prostate-cancer bone metastasis
    • Koeneman, KS, Kao, C, Ko, SC, Yang, L, Wada, Y, Kallmes, DF et al. (2000). Osteocalcin-directed gene therapy for prostate-cancer bone metastasis. World J Urol 18: 102-110.
    • (2000) World J Urol , vol.18 , pp. 102-110
    • Koeneman, K.S.1    Kao, C.2    Ko, S.C.3    Yang, L.4    Wada, Y.5    Kallmes, D.F.6
  • 31
    • 0023547004 scopus 로고
    • Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients
    • Horoszewicz, JS, Kawinski, E and Murphy, GP (1987). Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients. Anticancer Res 7: 927-935.
    • (1987) Anticancer Res , vol.7 , pp. 927-935
    • Horoszewicz, J.S.1    Kawinski, E.2    Murphy, G.P.3
  • 32
    • 0033820505 scopus 로고    scopus 로고
    • Prostate-specific suicide gene therapy using the prostate-specific membrane antigen promoter and enhancer
    • O'Keefe, DS, Uchida, A, Bacich, DJ, Watt, FB, Martorana, A, Molloy, PL et al. (2000). Prostate-specific suicide gene therapy using the prostate-specific membrane antigen promoter and enhancer. Prostate 45: 149-157.
    • (2000) Prostate , vol.45 , pp. 149-157
    • O'Keefe, D.S.1    Uchida, A.2    Bacich, D.J.3    Watt, F.B.4    Martorana, A.5    Molloy, P.L.6
  • 33
    • 0031042591 scopus 로고    scopus 로고
    • Prostate-specific membrane antigen expression in normal and malignant human tissues
    • Silver, DA, Pellicer, I, Fair, WR, Heston, WD and Cordon-Cardo, C (1997). Prostate-specific membrane antigen expression in normal and malignant human tissues. Clin Cancer Res 3: 81-85.
    • (1997) Clin Cancer Res , vol.3 , pp. 81-85
    • Silver, D.A.1    Pellicer, I.2    Fair, W.R.3    Heston, W.D.4    Cordon-Cardo, C.5
  • 34
    • 5444254496 scopus 로고    scopus 로고
    • Identifying the combination of the transcriptional regulatory sequences on prostate specific antigen and human glandular kallikrein genes
    • Tsui, KH, Wu, L, Chang, PL, Hsieh, ML and Juang, HH (2004). Identifying the combination of the transcriptional regulatory sequences on prostate specific antigen and human glandular kallikrein genes. J Urol 172: 2029-2034.
    • (2004) J Urol , vol.172 , pp. 2029-2034
    • Tsui, K.H.1    Wu, L.2    Chang, P.L.3    Hsieh, M.L.4    Juang, H.H.5
  • 35
    • 10344244475 scopus 로고    scopus 로고
    • Targeting prostate cancer with conditionally replicative adenovirus using PSMA enhancer
    • Lee, SJ, Zhang, Y, Lee, SD, Jung, C, Li, X, Kim, HS et al. (2004). Targeting prostate cancer with conditionally replicative adenovirus using PSMA enhancer. Mol Ther 10: 1051-1058.
    • (2004) Mol Ther , vol.10 , pp. 1051-1058
    • Lee, S.J.1    Zhang, Y.2    Lee, S.D.3    Jung, C.4    Li, X.5    Kim, H.S.6
  • 36
    • 4344625021 scopus 로고    scopus 로고
    • A novel TARP-promoter-based adenovirus against hormone-dependent and hormone-refractory prostate cancer
    • Cheng, WS, Kraaij, R, Nilsson, B, van der Weel, L, de Ridder, CM, Totterman, TH et al. (2004). A novel TARP-promoter-based adenovirus against hormone-dependent and hormone-refractory prostate cancer. Mol Ther 10: 355-364.
    • (2004) Mol Ther , vol.10 , pp. 355-364
    • Cheng, W.S.1    Kraaij, R.2    Nilsson, B.3    van der Weel, L.4    de Ridder, C.M.5    Totterman, T.H.6
  • 37
    • 0034175969 scopus 로고    scopus 로고
    • Gene therapy: Designer promoters for tumour targeting
    • Nettelbeck, DM, Jerome, V and Muller, R (2000). Gene therapy: Designer promoters for tumour targeting. Trends Genet 16: 174-181.
    • (2000) Trends Genet , vol.16 , pp. 174-181
    • Nettelbeck, D.M.1    Jerome, V.2    Muller, R.3
  • 39
    • 0348133605 scopus 로고    scopus 로고
    • Optimization of adenoviral vectors to direct highly amplified prostate-specific expression for imaging and gene therapy
    • Sato, M, Johnson, M, Zhang, L, Zhang, B, Le, K, Gambhir, SS et al. (2003). Optimization of adenoviral vectors to direct highly amplified prostate-specific expression for imaging and gene therapy. Mol Ther 8: 726-737.
    • (2003) Mol Ther , vol.8 , pp. 726-737
    • Sato, M.1    Johnson, M.2    Zhang, L.3    Zhang, B.4    Le, K.5    Gambhir, S.S.6
  • 40
    • 0032101616 scopus 로고    scopus 로고
    • Prostate-specific amplification of expanded polyglutamine expression: A novel approach for cancer gene therapy
    • Segawa, T, Takebayashi, H, Kakehi, Y, Yoshida, O, Narumiya, S and Kakizuka, A (1998). Prostate-specific amplification of expanded polyglutamine expression: A novel approach for cancer gene therapy. Cancer Res 58: 2282-2287.
    • (1998) Cancer Res , vol.58 , pp. 2282-2287
    • Segawa, T.1    Takebayashi, H.2    Kakehi, Y.3    Yoshida, O.4    Narumiya, S.5    Kakizuka, A.6
  • 41
    • 29444453285 scopus 로고    scopus 로고
    • Micro-PET/CT monitoring of herpes thymidine kinase suicide gene therapy in a prostate cancer xenograft: The advantage of a cell-specific transcriptional targeting approach
    • Johnson, M, Sato, M, Burton, J, Gambhir, SS, Carey, M and Wu, L (2005). Micro-PET/CT monitoring of herpes thymidine kinase suicide gene therapy in a prostate cancer xenograft: The advantage of a cell-specific transcriptional targeting approach. Mol Imaging 4: 463-472.
    • (2005) Mol Imaging , vol.4 , pp. 463-472
    • Johnson, M.1    Sato, M.2    Burton, J.3    Gambhir, S.S.4    Carey, M.5    Wu, L.6
  • 42
    • 28044473626 scopus 로고    scopus 로고
    • Imaging androgen receptor function during flutamide treatment in the LAPC9 xenograft model
    • Ilagan, R, Zhang, LJ, Pottratz, J, Le, K, Salas, S, Iyer, M et al. (2005). Imaging androgen receptor function during flutamide treatment in the LAPC9 xenograft model. Mol Cancer Ther 4: 1662-1669.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1662-1669
    • Ilagan, R.1    Zhang, L.J.2    Pottratz, J.3    Le, K.4    Salas, S.5    Iyer, M.6
  • 43
    • 0036870082 scopus 로고    scopus 로고
    • Amplified Muc1-specific gene expression in colon cancer cells utilizing a binary system in adenoviral vectors
    • Block, A, Milasinovic, D, Mueller, J, Schaefer, P, Schaefer, H and Greten, H (2002). Amplified Muc1-specific gene expression in colon cancer cells utilizing a binary system in adenoviral vectors. Anticancer Res 22: 3285-3292.
    • (2002) Anticancer Res , vol.22 , pp. 3285-3292
    • Block, A.1    Milasinovic, D.2    Mueller, J.3    Schaefer, P.4    Schaefer, H.5    Greten, H.6
  • 44
    • 33645790767 scopus 로고    scopus 로고
    • Noninvasive indirect imaging of vascular endothelial growth factor gene expression using bioluminescence imaging in living transgenic mice
    • Wang, Y, Iyer, M, Annala, A, Wu, L, Carey, M and Gambhir, SS (2006). Noninvasive indirect imaging of vascular endothelial growth factor gene expression using bioluminescence imaging in living transgenic mice. Physiol Genomics 24: 173-180.
    • (2006) Physiol Genomics , vol.24 , pp. 173-180
    • Wang, Y.1    Iyer, M.2    Annala, A.3    Wu, L.4    Carey, M.5    Gambhir, S.S.6
  • 45
    • 4644262107 scopus 로고    scopus 로고
    • Highly specific transgene expression mediated by a complex adenovirus vector incorporating a prostate-specific amplification feedback loop
    • Woraratanadharm, J, Rubinchik, S, Yu, H, Fan, F, Morrow, SM and Dong, JY (2004). Highly specific transgene expression mediated by a complex adenovirus vector incorporating a prostate-specific amplification feedback loop. Gene Ther 11: 1399-1407.
    • (2004) Gene Ther , vol.11 , pp. 1399-1407
    • Woraratanadharm, J.1    Rubinchik, S.2    Yu, H.3    Fan, F.4    Morrow, S.M.5    Dong, J.Y.6
  • 46
    • 0032539762 scopus 로고    scopus 로고
    • Enhanced and specific gene expression via tissue-specific production of Cre recombinase using adenovirus vector
    • Sato, Y, Tanaka, K, Lee, G, Kanegae, Y, Sakai, Y, Kaneko, S et al. (1998). Enhanced and specific gene expression via tissue-specific production of Cre recombinase using adenovirus vector. Biochem Biophys Res Commun 244: 455-462.
    • (1998) Biochem Biophys Res Commun , vol.244 , pp. 455-462
    • Sato, Y.1    Tanaka, K.2    Lee, G.3    Kanegae, Y.4    Sakai, Y.5    Kaneko, S.6
  • 47
    • 0036895176 scopus 로고    scopus 로고
    • Adenovirus mediated prostate specific enzyme prodrug gene therapy using prostate specific antigen promoter enhanced by the Cre-loxP system
    • Yoshimura, I, Ikegami, S, Suzuki, S, Tadakuma, T and Hayakawa, M (2002). Adenovirus mediated prostate specific enzyme prodrug gene therapy using prostate specific antigen promoter enhanced by the Cre-loxP system. J Urol 168: 2659-2664.
    • (2002) J Urol , vol.168 , pp. 2659-2664
    • Yoshimura, I.1    Ikegami, S.2    Suzuki, S.3    Tadakuma, T.4    Hayakawa, M.5
  • 48
    • 0036808742 scopus 로고    scopus 로고
    • Development of gene therapy using prostate-specific membrane antigen promoter/enhancer with Cre Recombinase/LoxP system for prostate cancer cells under androgen ablation condition
    • Ikegami, S, Tadakuma, T, Suzuki, S, Yoshimura, I, Asano, T and Hayakawa, M (2002). Development of gene therapy using prostate-specific membrane antigen promoter/enhancer with Cre Recombinase/LoxP system for prostate cancer cells under androgen ablation condition. Jpn J Cancer Res 93: 1154-1163.
    • (2002) Jpn J Cancer Res , vol.93 , pp. 1154-1163
    • Ikegami, S.1    Tadakuma, T.2    Suzuki, S.3    Yoshimura, I.4    Asano, T.5    Hayakawa, M.6
  • 49
    • 1942425052 scopus 로고    scopus 로고
    • Treatment efficiency of a suicide gene therapy using prostate-specific membrane antigen promoter/enhancer in a castrated mouse model of prostate cancer
    • Ikegami, S, Tadakuma, T, Ono, T, Suzuki, S, Yoshimura, I, Asano, T et al. (2004). Treatment efficiency of a suicide gene therapy using prostate-specific membrane antigen promoter/enhancer in a castrated mouse model of prostate cancer. Cancer Sci 95: 367-370.
    • (2004) Cancer Sci , vol.95 , pp. 367-370
    • Ikegami, S.1    Tadakuma, T.2    Ono, T.3    Suzuki, S.4    Yoshimura, I.5    Asano, T.6
  • 50
    • 0042161800 scopus 로고    scopus 로고
    • Induction of cre recombinase activity using modified androgen receptor ligand binding domains: A sensitive assay for ligand-receptor interactions
    • Kaczmarczyk, SJ and Green, JE (2003). Induction of cre recombinase activity using modified androgen receptor ligand binding domains: A sensitive assay for ligand-receptor interactions. Nucleic Acids Res 31: E86.
    • (2003) Nucleic Acids Res , vol.31
    • Kaczmarczyk, S.J.1    Green, J.E.2
  • 51
    • 33947242506 scopus 로고    scopus 로고
    • Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via alpha6-integrins
    • Stevenson, M, Hale, AB, Hale, SJ, Green, NK, Black, G, Fisher, KD et al. (2007). Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via alpha6-integrins. Cancer Gene Ther 14: 335-345.
    • (2007) Cancer Gene Ther , vol.14 , pp. 335-345
    • Stevenson, M.1    Hale, A.B.2    Hale, S.J.3    Green, N.K.4    Black, G.5    Fisher, K.D.6
  • 52
    • 33645290818 scopus 로고    scopus 로고
    • Photochemically enhanced transduction of polymer-complexed adenovirus targeted to the epidermal growth factor receptor
    • Bonsted, A, Engesaeter, BO, Hogset, A, Maelandsmo, GM, Prasmickaite, L, D'Oliveira, C et al. (2006). Photochemically enhanced transduction of polymer-complexed adenovirus targeted to the epidermal growth factor receptor. J Gene Med 8: 286-297.
    • (2006) J Gene Med , vol.8 , pp. 286-297
    • Bonsted, A.1    Engesaeter, B.O.2    Hogset, A.3    Maelandsmo, G.M.4    Prasmickaite, L.5    D'Oliveira, C.6
  • 53
    • 12344284722 scopus 로고    scopus 로고
    • Prostate specific membrane antigen (PSMA) is a tissue-specific target for adenoviral transduction of prostate cancer in vitro
    • Kraaij, R, van Rijswijk, AL, Oomen, MH, Haisma, HJ and Bangma, CH (2005). Prostate specific membrane antigen (PSMA) is a tissue-specific target for adenoviral transduction of prostate cancer in vitro. Prostate 62: 253-259.
    • (2005) Prostate , vol.62 , pp. 253-259
    • Kraaij, R.1    van Rijswijk, A.L.2    Oomen, M.H.3    Haisma, H.J.4    Bangma, C.H.5
  • 54
    • 0037338436 scopus 로고    scopus 로고
    • Molecular imaging in living subjects: Seeing fundamental biological processes in a new light
    • Massoud, TF and Gambhir, SS (2003). Molecular imaging in living subjects: Seeing fundamental biological processes in a new light. Genes Dev 17: 545-580.
    • (2003) Genes Dev , vol.17 , pp. 545-580
    • Massoud, T.F.1    Gambhir, S.S.2
  • 55
    • 29444443670 scopus 로고    scopus 로고
    • Applications of molecular imaging in cancer gene therapy
    • Iyer, M, Sato, M, Johnson, M, Gambhir, SS and Wu, L (2005). Applications of molecular imaging in cancer gene therapy. Curr Gene Ther 5 607-618.
    • (2005) Curr Gene Ther , vol.5 , pp. 607-618
    • Iyer, M.1    Sato, M.2    Johnson, M.3    Gambhir, S.S.4    Wu, L.5
  • 56
    • 0021971882 scopus 로고
    • Inhibition of HSV-transformed murine cells by nucleoside analogs, 2′-NDG and 2′-nor-cGMP: Mechanisms of inhibition and reversal by exogenous nucleosides
    • Oliver, S, Bubley, G and Crumpacker, C (1985). Inhibition of HSV-transformed murine cells by nucleoside analogs, 2′-NDG and 2′-nor-cGMP: Mechanisms of inhibition and reversal by exogenous nucleosides. Virology 145: 84-93.
    • (1985) Virology , vol.145 , pp. 84-93
    • Oliver, S.1    Bubley, G.2    Crumpacker, C.3
  • 58
    • 9544242826 scopus 로고    scopus 로고
    • Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy
    • Tjuvajev, JG, Finn, R, Watanabe, K, Joshi, R, Oku, T, Kennedy, J et al. (1996). Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy. Cancer Res 56: 4087-4095.
    • (1996) Cancer Res , vol.56 , pp. 4087-4095
    • Tjuvajev, J.G.1    Finn, R.2    Watanabe, K.3    Joshi, R.4    Oku, T.5    Kennedy, J.6
  • 59
    • 17144471900 scopus 로고    scopus 로고
    • Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography
    • Tjuvajev, JG, Avril, N, Oku, T, Sasajima, T, Miyagawa, T, Joshi, R et al. (1998). Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res 58: 4333-4341.
    • (1998) Cancer Res , vol.58 , pp. 4333-4341
    • Tjuvajev, J.G.1    Avril, N.2    Oku, T.3    Sasajima, T.4    Miyagawa, T.5    Joshi, R.6
  • 60
    • 0344564162 scopus 로고    scopus 로고
    • Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo
    • Tjuvajev, JG, Chen, SH, Joshi, A, Joshi, R, Guo, ZS, Balatoni, J et al. (1999). Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo. Cancer Res 59: 5186-5193.
    • (1999) Cancer Res , vol.59 , pp. 5186-5193
    • Tjuvajev, J.G.1    Chen, S.H.2    Joshi, A.3    Joshi, R.4    Guo, Z.S.5    Balatoni, J.6
  • 61
    • 0031742514 scopus 로고    scopus 로고
    • Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir
    • Gambhir, SS, Barrio, JR, Wu, L, Iyer, M, Namavari, M, Satyamurthy, N et al. (1998). Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir. J Nucl Med 39: 2003-2011.
    • (1998) J Nucl Med , vol.39 , pp. 2003-2011
    • Gambhir, S.S.1    Barrio, J.R.2    Wu, L.3    Iyer, M.4    Namavari, M.5    Satyamurthy, N.6
  • 64
    • 0035807838 scopus 로고    scopus 로고
    • Two-step transcriptional amplification as a method for imaging reporter gene expression using weak promoters
    • Iyer, M, Wu, L, Carey, M, Wang, Y, Smallwood, A and Gambhir, SS (2001). Two-step transcriptional amplification as a method for imaging reporter gene expression using weak promoters. Proc Natl Acad Sci USA 98 14595-14600.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 14595-14600
    • Iyer, M.1    Wu, L.2    Carey, M.3    Wang, Y.4    Smallwood, A.5    Gambhir, S.S.6
  • 65
    • 0036708008 scopus 로고    scopus 로고
    • Characterization of herpes simplex virus type 1 thymidine kinase mutants engineered for improved ganciclovir or acyclovir activity
    • Kokoris, MS and Black, ME (2002). Characterization of herpes simplex virus type 1 thymidine kinase mutants engineered for improved ganciclovir or acyclovir activity. Protein Sci 11: 2267-2272.
    • (2002) Protein Sci , vol.11 , pp. 2267-2272
    • Kokoris, M.S.1    Black, M.E.2
  • 66
    • 0034098464 scopus 로고    scopus 로고
    • In vitro evaluation of mutant HSV-1 thymidine kinases for suicide gene therapy
    • Kokoris, MS, Sabo, P and Black, ME (2000). In vitro evaluation of mutant HSV-1 thymidine kinases for suicide gene therapy. Anticancer Res 20: 959-963.
    • (2000) Anticancer Res , vol.20 , pp. 959-963
    • Kokoris, M.S.1    Sabo, P.2    Black, M.E.3
  • 67
    • 0242385251 scopus 로고    scopus 로고
    • A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography
    • Gambhir, SS, Bauer, E, Black, ME, Liang, Q, Kokoris, MS, Barrio, JR et al. (2000). A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. Proc Natl Acad Sci USA 97: 2785-2790.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2785-2790
    • Gambhir, S.S.1    Bauer, E.2    Black, M.E.3    Liang, Q.4    Kokoris, M.S.5    Barrio, J.R.6
  • 68
    • 0242355152 scopus 로고    scopus 로고
    • 14C]FIAU for imaging of HSV1-tk reporter gene expression: Adenoviral infection vs stable transfection
    • 14C]FIAU for imaging of HSV1-tk reporter gene expression: Adenoviral infection vs stable transfection. Eur J Nucl Med Mol Imaging 30 1547-1560.
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , pp. 1547-1560
    • Min, J.J.1    Iyer, M.2    Gambhir, S.S.3
  • 69
    • 20444466384 scopus 로고    scopus 로고
    • Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients
    • Penuelas, I, Mazzolini, G, Boan, JF, Sangro, B, Marti-Climent, J, Ruiz, M et al. (2005). Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients. Gastroenterology 128: 1787-1795.
    • (2005) Gastroenterology , vol.128 , pp. 1787-1795
    • Penuelas, I.1    Mazzolini, G.2    Boan, J.F.3    Sangro, B.4    Marti-Climent, J.5    Ruiz, M.6
  • 70
    • 0036732003 scopus 로고    scopus 로고
    • Sodium iodide symporter: Its role in nuclear medicine
    • Chung, JK (2002). Sodium iodide symporter: Its role in nuclear medicine. J Nucl Med 43: 1188-1200.
    • (2002) J Nucl Med , vol.43 , pp. 1188-1200
    • Chung, J.K.1
  • 71
    • 0030053759 scopus 로고    scopus 로고
    • Cloning and characterization of the thyroid iodide transporter
    • Dai, G, Levy, O and Carrasco, N (1996). Cloning and characterization of the thyroid iodide transporter. Nature 379: 458-460.
    • (1996) Nature , vol.379 , pp. 458-460
    • Dai, G.1    Levy, O.2    Carrasco, N.3
  • 73
    • 0030955364 scopus 로고    scopus 로고
    • Iodide uptake and experimental 1311 therapy in transplanted undifferentiated thyroid cancer cells expressing the Na+/I-symporter gene
    • Shimura, H, Haraguchi, K, Miyazaki, A, Endo, T and Onaya, T (1997). Iodide uptake and experimental 1311 therapy in transplanted undifferentiated thyroid cancer cells expressing the Na+/I-symporter gene. Endocrinology 138: 4493-4496.
    • (1997) Endocrinology , vol.138 , pp. 4493-4496
    • Shimura, H.1    Haraguchi, K.2    Miyazaki, A.3    Endo, T.4    Onaya, T.5
  • 74
    • 0035130285 scopus 로고    scopus 로고
    • Transfer of the human Nal symporter gene enhances iodide uptake in hepatoma cells
    • Haberkorn, U, Henze, M, Altmann, A, Jiang, S, Morr, I, Mahmut, M et al. (2001). Transfer of the human Nal symporter gene enhances iodide uptake in hepatoma cells. J Nucl Med 42: 317-325.
    • (2001) J Nucl Med , vol.42 , pp. 317-325
    • Haberkorn, U.1    Henze, M.2    Altmann, A.3    Jiang, S.4    Morr, I.5    Mahmut, M.6
  • 75
    • 0036401152 scopus 로고    scopus 로고
    • Adenovirus biodistribution and noninvasive imaging of gene expression in vivo by positron emission tomography using human sodium/iodide symporter as reporter gene
    • Groot-Wassink, T, Aboagye, EO, Glaser, M, Lemoine, NR and Vassaux, G (2002). Adenovirus biodistribution and noninvasive imaging of gene expression in vivo by positron emission tomography using human sodium/iodide symporter as reporter gene. Hum Gene Ther 13: 1723-1735.
    • (2002) Hum Gene Ther , vol.13 , pp. 1723-1735
    • Groot-Wassink, T.1    Aboagye, E.O.2    Glaser, M.3    Lemoine, N.R.4    Vassaux, G.5
  • 76
    • 1642525140 scopus 로고    scopus 로고
    • Quantitative imaging of Na/I symporter transgene expression using positron emission tomography in the living animal
    • Groot-Wassink, T, Aboagye, EO, Wang, Y, Lemoine, NR, Reader, AJ and Vassaux, G (2004). Quantitative imaging of Na/I symporter transgene expression using positron emission tomography in the living animal. Mol Ther 9: 436-442.
    • (2004) Mol Ther , vol.9 , pp. 436-442
    • Groot-Wassink, T.1    Aboagye, E.O.2    Wang, Y.3    Lemoine, N.R.4    Reader, A.J.5    Vassaux, G.6
  • 77
    • 0033083046 scopus 로고    scopus 로고
    • Radioisotope concentrator gene therapy using the sodium/iodide symporter gene
    • Mandell, RB, Mandell, LZ and Link, CJ Jr. (1999). Radioisotope concentrator gene therapy using the sodium/iodide symporter gene. Cancer Res 59: 661-668.
    • (1999) Cancer Res , vol.59 , pp. 661-668
    • Mandell, R.B.1    Mandell, L.Z.2    Link Jr., C.J.3
  • 78
    • 0036714719 scopus 로고    scopus 로고
    • In vivo imaging and radioiodine therapy following sodium iodide symporter gene transfer in animal model of intracerebral gliomas
    • Cho, JY, Shen, DH, Yang, W, Williams, B, Buckwalter, TL, La Perle, KM et al. (2002). In vivo imaging and radioiodine therapy following sodium iodide symporter gene transfer in animal model of intracerebral gliomas. Gene Ther 9: 1139-1145.
    • (2002) Gene Ther , vol.9 , pp. 1139-1145
    • Cho, J.Y.1    Shen, D.H.2    Yang, W.3    Williams, B.4    Buckwalter, T.L.5    La Perle, K.M.6
  • 79
    • 0033693586 scopus 로고    scopus 로고
    • Treatment of prostate cancer by radioiodine therapy after tissue-specific expression of the sodium iodide symporter
    • Spitzweg, C, O'Connor, MK, Bergert, ER, Tindall, DJ, Young, CY and Morris, JC (2000). Treatment of prostate cancer by radioiodine therapy after tissue-specific expression of the sodium iodide symporter. Cancer Res 60: 6526-6530.
    • (2000) Cancer Res , vol.60 , pp. 6526-6530
    • Spitzweg, C.1    O'Connor, M.K.2    Bergert, E.R.3    Tindall, D.J.4    Young, C.Y.5    Morris, J.C.6
  • 80
    • 30344477005 scopus 로고    scopus 로고
    • Second-generation replication-competent oncolytic adenovirus armed with improved suicide genes and ADP gene demonstrates greater efficacy without increased toxicity
    • Barton, KN, Paielli, D, Zhang, Y, Koul, S, Brown, SL, Lu, M et al. (2006). Second-generation replication-competent oncolytic adenovirus armed with improved suicide genes and ADP gene demonstrates greater efficacy without increased toxicity. Mol Ther 13: 347-356.
    • (2006) Mol Ther , vol.13 , pp. 347-356
    • Barton, K.N.1    Paielli, D.2    Zhang, Y.3    Koul, S.4    Brown, S.L.5    Lu, M.6
  • 81
    • 27744563596 scopus 로고    scopus 로고
    • A preclinical large animal model of adenovirus-mediated expression of the sodium-iodide symporter for radioiodide imaging and therapy of locally recurrent prostate cancer
    • Dwyer, RM, Schatz, SM, Bergert, ER, Myers, RM, Harvey, ME, Classic, KL et al. (2005). A preclinical large animal model of adenovirus-mediated expression of the sodium-iodide symporter for radioiodide imaging and therapy of locally recurrent prostate cancer. Mol Ther 12: 835-841.
    • (2005) Mol Ther , vol.12 , pp. 835-841
    • Dwyer, R.M.1    Schatz, S.M.2    Bergert, E.R.3    Myers, R.M.4    Harvey, M.E.5    Classic, K.L.6
  • 82
    • 33646886604 scopus 로고    scopus 로고
    • Therapeutic vaccines for prostate cancer
    • Tarassoff, CP, Arlen, PM and Gulley, JL (2006). Therapeutic vaccines for prostate cancer. Oncologist 11: 451-462.
    • (2006) Oncologist , vol.11 , pp. 451-462
    • Tarassoff, C.P.1    Arlen, P.M.2    Gulley, J.L.3
  • 83
    • 0036324470 scopus 로고    scopus 로고
    • Gene therapy of prostate cancer: Current and future directions
    • Mabjeesh, NJ, Zhong, H and Simons, JW (2002). Gene therapy of prostate cancer: Current and future directions. Endocr Relat Cancer 9 115-139.
    • (2002) Endocr Relat Cancer , vol.9 , pp. 115-139
    • Mabjeesh, N.J.1    Zhong, H.2    Simons, J.W.3
  • 84
    • 0032741439 scopus 로고    scopus 로고
    • Induction of immunity to prostate cancer antigens: Results of a clinical trial of vaccination with irradiated autologous prostate tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor using ex vivo gene transfer
    • Simons, JW, Mikhak, B, Chang, JF, DeMarzo, AM, Carducci, MA, Lim, M et al. (1999). Induction of immunity to prostate cancer antigens: results of a clinical trial of vaccination with irradiated autologous prostate tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor using ex vivo gene transfer. Cancer Res 59: 5160-5168.
    • (1999) Cancer Res , vol.59 , pp. 5160-5168
    • Simons, J.W.1    Mikhak, B.2    Chang, J.F.3    DeMarzo, A.M.4    Carducci, M.A.5    Lim, M.6
  • 85
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff, G, Jaffee, E, Lazenby, A, Golumbek, P, Levitsky, H, Brose, K et al. (1993). Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA 90: 3539-3543.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3    Golumbek, P.4    Levitsky, H.5    Brose, K.6
  • 86
    • 20444453277 scopus 로고    scopus 로고
    • Delayed disease progression after allogeneic cell vaccination in hormone-resistant prostate cancer and correlation with immunologic variables
    • Michael, A, Ball, G, Quatan, N, Wushishi, F, Russell, N, Whelan, J et al. (2005). Delayed disease progression after allogeneic cell vaccination in hormone-resistant prostate cancer and correlation with immunologic variables. Clin Cancer Res 11: 4469-4478.
    • (2005) Clin Cancer Res , vol.11 , pp. 4469-4478
    • Michael, A.1    Ball, G.2    Quatan, N.3    Wushishi, F.4    Russell, N.5    Whelan, J.6
  • 87
    • 22144472230 scopus 로고    scopus 로고
    • Antiandrogen, vaccine and combination therapy in patients with nonmetastatic hormone refractory prostate cancer
    • Arlen, PM, Gulley, JL, Todd, N, Lieberman, R, Steinberg, SM, Morin, S et al. (2005). Antiandrogen, vaccine and combination therapy in patients with nonmetastatic hormone refractory prostate cancer. J Urol 174: 539-546.
    • (2005) J Urol , vol.174 , pp. 539-546
    • Arlen, P.M.1    Gulley, J.L.2    Todd, N.3    Lieberman, R.4    Steinberg, S.M.5    Morin, S.6
  • 88
    • 20944441967 scopus 로고    scopus 로고
    • Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer
    • Gulley, JL, Arlen, PM, Bastian, A, Morin, S, Marte, J, Beetham, P et al. (2005). Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer. Clin Cancer Res 11: 3353-3362.
    • (2005) Clin Cancer Res , vol.11 , pp. 3353-3362
    • Gulley, J.L.1    Arlen, P.M.2    Bastian, A.3    Morin, S.4    Marte, J.5    Beetham, P.6
  • 89
    • 2942644684 scopus 로고    scopus 로고
    • Phase II randomized study of vaccine treatment of advanced prostate cancer (E7897): A trial of the Eastern Cooperative Oncology Group
    • Kaufman, HL, Wang, W, Manola, J, DiPaola, RS, Ko, YJ, Sweeney, C et al. (2004). Phase II randomized study of vaccine treatment of advanced prostate cancer (E7897): A trial of the Eastern Cooperative Oncology Group. J Clin Oncol 22: 2122-2132.
    • (2004) J Clin Oncol , vol.22 , pp. 2122-2132
    • Kaufman, H.L.1    Wang, W.2    Manola, J.3    DiPaola, R.S.4    Ko, Y.J.5    Sweeney, C.6
  • 90
    • 8644259104 scopus 로고    scopus 로고
    • Dendritic cell based vaccines: Progress in immunotherapy studies for prostate cancer
    • Ragde, H, Cavanagh, WA and Tjoa, BA (2004). Dendritic cell based vaccines: Progress in immunotherapy studies for prostate cancer. J Urol 172: 2532-2538.
    • (2004) J Urol , vol.172 , pp. 2532-2538
    • Ragde, H.1    Cavanagh, W.A.2    Tjoa, B.A.3
  • 91
    • 0034106147 scopus 로고    scopus 로고
    • Higher-dose and less frequent dendritic cell infusions with PSMA peptides in hormone-refractory metastatic prostate cancer patients
    • Murphy, GP, Tjoa, BA, Simmons, SJ, Rogers, MK, Kenny, GM and Jarisch, J (2000). Higher-dose and less frequent dendritic cell infusions with PSMA peptides in hormone-refractory metastatic prostate cancer patients. Prostate 43: 59-62.
    • (2000) Prostate , vol.43 , pp. 59-62
    • Murphy, G.P.1    Tjoa, B.A.2    Simmons, S.J.3    Rogers, M.K.4    Kenny, G.M.5    Jarisch, J.6
  • 92
    • 0034652619 scopus 로고    scopus 로고
    • Dendritic cell-based immunotherapy of prostate cancer: Immune monitoring of a phase II clinical trial
    • Lodge, PA, Jones, LA, Bader, RA, Murphy, GP and Salgaller, ML (2000). Dendritic cell-based immunotherapy of prostate cancer: Immune monitoring of a phase II clinical trial. Cancer Res 60: 829-833.
    • (2000) Cancer Res , vol.60 , pp. 829-833
    • Lodge, P.A.1    Jones, L.A.2    Bader, R.A.3    Murphy, G.P.4    Salgaller, M.L.5
  • 93
    • 2342640119 scopus 로고    scopus 로고
    • Vaccination of prostatectomized prostate cancer patients in biochemical relapse, with autologous dendritic cells pulsed with recombinant human PSA
    • Barrou, B, Benoit, G, Ouldkaci, M, Cussenot, O, Salcedo, M, Agrawal, S et al. (2004). Vaccination of prostatectomized prostate cancer patients in biochemical relapse, with autologous dendritic cells pulsed with recombinant human PSA. Cancer Immunol Immunother 53: 453-460.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 453-460
    • Barrou, B.1    Benoit, G.2    Ouldkaci, M.3    Cussenot, O.4    Salcedo, M.5    Agrawal, S.6
  • 94
    • 0036167308 scopus 로고    scopus 로고
    • Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors
    • Heiser, A, Coleman, D, Dannull, J, Yancey, D, Maurice, MA, Lallas, CD et al. (2002). Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. J Clin Invest 109: 409-417.
    • (2002) J Clin Invest , vol.109 , pp. 409-417
    • Heiser, A.1    Coleman, D.2    Dannull, J.3    Yancey, D.4    Maurice, M.A.5    Lallas, C.D.6
  • 95
    • 3242747658 scopus 로고    scopus 로고
    • Immunotherapy (APC8015, Provenge) targeting prostatic acid phosphatase can induce durable remission of metastatic androgen-independent prostate cancer: A Phase 2 trial
    • Burch, PA, Croghan, GA, Gastineau, DA, Jones, LA, Kaur, JS, Kylstra, JW et al. (2004). Immunotherapy (APC8015, Provenge) targeting prostatic acid phosphatase can induce durable remission of metastatic androgen-independent prostate cancer: A Phase 2 trial. Prostate 60: 197-204.
    • (2004) Prostate , vol.60 , pp. 197-204
    • Burch, P.A.1    Croghan, G.A.2    Gastineau, D.A.3    Jones, L.A.4    Kaur, J.S.5    Kylstra, J.W.6
  • 96
    • 0034554863 scopus 로고    scopus 로고
    • Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells
    • Small, EJ, Fratesi, P, Reese, DM, Strang, G, Laus, R, Peshwa, MV et al. (2000). Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells. J Clin Oncol 18: 3894-3903.
    • (2000) J Clin Oncol , vol.18 , pp. 3894-3903
    • Small, E.J.1    Fratesi, P.2    Reese, D.M.3    Strang, G.4    Laus, R.5    Peshwa, M.V.6
  • 97
    • 27944510121 scopus 로고    scopus 로고
    • Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity
    • Lipinski, KS, Pelech, S, Mountain, A, Irvine, AS, Kraaij, R, Bangma, CH et al. (2006). Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity. Cancer Immunol Immunother 55 347-354.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 347-354
    • Lipinski, K.S.1    Pelech, S.2    Mountain, A.3    Irvine, A.S.4    Kraaij, R.5    Bangma, C.H.6
  • 98
    • 0036167572 scopus 로고    scopus 로고
    • Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL
    • Voelkel-Johnson, C, King, DL and Norris, JS (2002). Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL. Cancer Gene Ther 9: 164-172.
    • (2002) Cancer Gene Ther , vol.9 , pp. 164-172
    • Voelkel-Johnson, C.1    King, D.L.2    Norris, J.S.3
  • 99
    • 0036892209 scopus 로고    scopus 로고
    • Synergy is achieved by complementation with Apo2L/TRAIL and actinomycin D in Apo2L/ TRAIL-mediated apoptosis of prostate cancer cells: Role of XIAP in resistance
    • Ng, CP, Zisman, A and Bonavida, B (2002). Synergy is achieved by complementation with Apo2L/TRAIL and actinomycin D in Apo2L/ TRAIL-mediated apoptosis of prostate cancer cells: Role of XIAP in resistance. Prostate 53: 286-299.
    • (2002) Prostate , vol.53 , pp. 286-299
    • Ng, C.P.1    Zisman, A.2    Bonavida, B.3
  • 100
    • 14844345670 scopus 로고    scopus 로고
    • Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts
    • Vanoosten, RL, Moore, JM, Ludwig, AT and Griffith, TS (2005). Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts. Mol Ther 11: 542-552.
    • (2005) Mol Ther , vol.11 , pp. 542-552
    • Vanoosten, R.L.1    Moore, J.M.2    Ludwig, A.T.3    Griffith, T.S.4
  • 101
    • 0035191647 scopus 로고    scopus 로고
    • A complex adenovirus vector that delivers FASL-GFP with combined prostate-specific and tetracycline-regulated expression
    • Rubinchik, S, Wang, D, Yu, H, Fan, F, Luo, M, Norris, JS et al. (2001). A complex adenovirus vector that delivers FASL-GFP with combined prostate-specific and tetracycline-regulated expression. Mol Ther 4: 416-426.
    • (2001) Mol Ther , vol.4 , pp. 416-426
    • Rubinchik, S.1    Wang, D.2    Yu, H.3    Fan, F.4    Luo, M.5    Norris, J.S.6
  • 102
    • 0345732497 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24
    • Lebedeva, IV, Sarkar, D, Su, ZZ, Kitada, S, Dent, P, Stein, CA et al. (2003). Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24. Oncogene 22: 8758-8773.
    • (2003) Oncogene , vol.22 , pp. 8758-8773
    • Lebedeva, I.V.1    Sarkar, D.2    Su, Z.Z.3    Kitada, S.4    Dent, P.5    Stein, C.A.6
  • 103
    • 20044366739 scopus 로고    scopus 로고
    • Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation-associated-7 (mda-7)/interleukin-24 (IL-24) gene
    • Saito, Y, Miyahara, R, Gopalan, B, Litvak, A, Inoue, S, Shanker, M et al. (2005). Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation-associated-7 (mda-7)/interleukin-24 (IL-24) gene. Cancer Gene Ther 12: 238-247.
    • (2005) Cancer Gene Ther , vol.12 , pp. 238-247
    • Saito, Y.1    Miyahara, R.2    Gopalan, B.3    Litvak, A.4    Inoue, S.5    Shanker, M.6
  • 104
    • 27844459421 scopus 로고    scopus 로고
    • Unique aspects of mda-7/IL-24 antitumor bystander activity: Establishing a role for secretion of MDA-7/IL-24 protein by normal cells
    • Su, Z, Emdad, L, Sauane, M, Lebedeva, IV, Sarkar, D, Gupta, P et al. (2005). Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells. Oncogene 24: 7552-7566.
    • (2005) Oncogene , vol.24 , pp. 7552-7566
    • Su, Z.1    Emdad, L.2    Sauane, M.3    Lebedeva, I.V.4    Sarkar, D.5    Gupta, P.6
  • 105
    • 0037260825 scopus 로고    scopus 로고
    • Adenoviral vector-mediated mRTVP-1 gene therapy for prostate cancer
    • Satoh, T, Timme, TL, Saika, T, Ebara, S, Yang, G, Wang, J et al. (2003). Adenoviral vector-mediated mRTVP-1 gene therapy for prostate cancer. Hum Gene Ther 14: 91-101.
    • (2003) Hum Gene Ther , vol.14 , pp. 91-101
    • Satoh, T.1    Timme, T.L.2    Saika, T.3    Ebara, S.4    Yang, G.5    Wang, J.6
  • 106
    • 0030790684 scopus 로고    scopus 로고
    • Prostate attenuated replication competent adenovirus (ARCA) CN706: A selective cytotoxic for prostate-specific antigen-positive prostate cancer cells
    • Rodriguez, R, Schuur, ER, Lim, HY, Henderson, GA, Simons, JW and Henderson, DR (1997). Prostate attenuated replication competent adenovirus (ARCA) CN706: A selective cytotoxic for prostate-specific antigen-positive prostate cancer cells. Cancer Res 57: 2559-2563.
    • (1997) Cancer Res , vol.57 , pp. 2559-2563
    • Rodriguez, R.1    Schuur, E.R.2    Lim, H.Y.3    Henderson, G.A.4    Simons, J.W.5    Henderson, D.R.6
  • 107
    • 0035879042 scopus 로고    scopus 로고
    • CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity
    • Chen, Y, DeWeese, T, Dilley, J, Zhang, Y, Li, Y, Ramesh, N et al. (2001). CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity. Cancer Res 61: 5453-5460.
    • (2001) Cancer Res , vol.61 , pp. 5453-5460
    • Chen, Y.1    DeWeese, T.2    Dilley, J.3    Zhang, Y.4    Li, Y.5    Ramesh, N.6
  • 108
    • 0035887153 scopus 로고    scopus 로고
    • A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy
    • DeWeese, TL, van der Poel, H, Li, S, Mikhak, B, Drew, R, Goemann, M et al. (2001). A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy. Cancer Res 61: 7464-7472.
    • (2001) Cancer Res , vol.61 , pp. 7464-7472
    • DeWeese, T.L.1    van der Poel, H.2    Li, S.3    Mikhak, B.4    Drew, R.5    Goemann, M.6
  • 109
    • 0033199188 scopus 로고    scopus 로고
    • The addition of adenovirus type 5 region E3 enables calydon virus 787 to eliminate distant prostate tumor xenografts
    • Yu, DC, Chen, Y, Seng, M, Dilley, J and Henderson, DR (1999). The addition of adenovirus type 5 region E3 enables calydon virus 787 to eliminate distant prostate tumor xenografts. Cancer Res 59: 4200-4203.
    • (1999) Cancer Res , vol.59 , pp. 4200-4203
    • Yu, D.C.1    Chen, Y.2    Seng, M.3    Dilley, J.4    Henderson, D.R.5
  • 110
    • 22944434253 scopus 로고    scopus 로고
    • Oncolytic adenovirus CG7870 in combination with radiation demonstrates synergistic enhancements of antitumor efficacy without loss of specificity
    • Dilley, J, Reddy, S, Ko, D, Nguyen, N, Rojas, G, Working, P et al. (2005). Oncolytic adenovirus CG7870 in combination with radiation demonstrates synergistic enhancements of antitumor efficacy without loss of specificity. Cancer Gene Ther 12: 715-722.
    • (2005) Cancer Gene Ther , vol.12 , pp. 715-722
    • Dilley, J.1    Reddy, S.2    Ko, D.3    Nguyen, N.4    Rojas, G.5    Working, P.6
  • 111
    • 0035863499 scopus 로고    scopus 로고
    • Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel
    • Yu, DC, Chen, Y, Dilley, J, Li, Y, Embry, M, Zhang, H et al. (2001). Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel. Cancer Res 61: 517-525.
    • (2001) Cancer Res , vol.61 , pp. 517-525
    • Yu, D.C.1    Chen, Y.2    Dilley, J.3    Li, Y.4    Embry, M.5    Zhang, H.6
  • 112
    • 22944476168 scopus 로고    scopus 로고
    • Effects of Onyx-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin
    • Reid, TR, Freeman, S, Post, L, McCormick, F and Sze, DY (2005). Effects of Onyx-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin. Cancer Gene Ther 12: 673-681.
    • (2005) Cancer Gene Ther , vol.12 , pp. 673-681
    • Reid, T.R.1    Freeman, S.2    Post, L.3    McCormick, F.4    Sze, D.Y.5
  • 113
    • 0035863458 scopus 로고    scopus 로고
    • Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer
    • Nemunaitis, J, Khuri, F, Ganly, I, Arseneau, J, Posner, M, Vokes, E et al. (2001). Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer. J Clin Oncol 19: 289-298.
    • (2001) J Clin Oncol , vol.19 , pp. 289-298
    • Nemunaitis, J.1    Khuri, F.2    Ganly, I.3    Arseneau, J.4    Posner, M.5    Vokes, E.6
  • 114
    • 0035076823 scopus 로고    scopus 로고
    • Safety and feasibility of injection with an E1B-55 kda gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: A phase I trial
    • Mulvihill, S, Warren, R, Venook, A, Adler, A, Randlev, B, Heise, C et al. (2001). Safety and feasibility of injection with an E1B-55 kda gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: A phase I trial. Gene Ther 8: 308-315.
    • (2001) Gene Ther , vol.8 , pp. 308-315
    • Mulvihill, S.1    Warren, R.2    Venook, A.3    Adler, A.4    Randlev, B.5    Heise, C.6
  • 115
    • 3042770838 scopus 로고    scopus 로고
    • The dl1520 virus is found preferentially in tumor tissue after direct intratumoral injection in oral carcinoma
    • Morley, S, MacDonald, G, Kirn, D, Kaye, S, Brown, R and Soutar, D (2004). The dl1520 virus is found preferentially in tumor tissue after direct intratumoral injection in oral carcinoma. Clin Cancer Res 10: 4357-4362.
    • (2004) Clin Cancer Res , vol.10 , pp. 4357-4362
    • Morley, S.1    MacDonald, G.2    Kirn, D.3    Kaye, S.4    Brown, R.5    Soutar, D.6
  • 116
    • 0033831080 scopus 로고    scopus 로고
    • A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
    • Khuri, FR, Nemunaitis, J, Ganly, I, Arseneau, J, Tannock, IF, Romel, L et al. (2000). A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 6: 879-885.
    • (2000) Nat Med , vol.6 , pp. 879-885
    • Khuri, F.R.1    Nemunaitis, J.2    Ganly, I.3    Arseneau, J.4    Tannock, I.F.5    Romel, L.6
  • 117
    • 0037314610 scopus 로고    scopus 로고
    • A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma
    • Hecht, JR, Bedford, R, Abbruzzese, JL, Lahoti, S, Reid, TR, Soetikno, RM et al. (2003). A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma. Clin Cancer Res 9: 555-561.
    • (2003) Clin Cancer Res , vol.9 , pp. 555-561
    • Hecht, J.R.1    Bedford, R.2    Abbruzzese, J.L.3    Lahoti, S.4    Reid, T.R.5    Soetikno, R.M.6
  • 118
    • 12944328660 scopus 로고    scopus 로고
    • A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer
    • Ganly, I, Kirn, D, Eckhardt, G, Rodriguez, GI, Soutar, DS, Otto, R et al. (2000). A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer. Clin Cancer Res 6: 798-806.
    • (2000) Clin Cancer Res , vol.6 , pp. 798-806
    • Ganly, I.1    Kirn, D.2    Eckhardt, G.3    Rodriguez, G.I.4    Soutar, D.S.5    Otto, R.6
  • 119
    • 0033022039 scopus 로고    scopus 로고
    • p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication
    • Harada, JN and Berk, AJ (1999). p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication. J Virol 73: 5333-5344.
    • (1999) J Virol , vol.73 , pp. 5333-5344
    • Harada, J.N.1    Berk, A.J.2
  • 120
    • 0031798440 scopus 로고    scopus 로고
    • p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection
    • Goodrum, FD and Ornelles, DA (1998). p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection. J Virol 72: 9479-9490.
    • (1998) J Virol , vol.72 , pp. 9479-9490
    • Goodrum, F.D.1    Ornelles, D.A.2
  • 121
    • 0036891811 scopus 로고    scopus 로고
    • Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes
    • Edwards, SJ, Dix, BR, Myers, CJ, Dobson-Le, D, Huschtscha, L, Hibma, M et al. (2002). Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes. J Virol 76: 12483-12490.
    • (2002) J Virol , vol.76 , pp. 12483-12490
    • Edwards, S.J.1    Dix, B.R.2    Myers, C.J.3    Dobson-Le, D.4    Huschtscha, L.5    Hibma, M.6
  • 122
    • 0031743945 scopus 로고    scopus 로고
    • Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells
    • Rothmann, T, Hengstermann, A, Whitaker, NJ, Scheffner, M and zur Hausen, H (1998). Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells. J. Virol 72: 9470-9478.
    • (1998) J. Virol , vol.72 , pp. 9470-9478
    • Rothmann, T.1    Hengstermann, A.2    Whitaker, N.J.3    Scheffner, M.4    zur Hausen, H.5
  • 123
    • 19944363519 scopus 로고    scopus 로고
    • Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity
    • O'Shea, CC, Johnson, L, Bagus, B, Choi, S, Nicholas, C, Shen, A et al. (2004). Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity. Cancer Cell 6: 611-623.
    • (2004) Cancer Cell , vol.6 , pp. 611-623
    • O'Shea, C.C.1    Johnson, L.2    Bagus, B.3    Choi, S.4    Nicholas, C.5    Shen, A.6
  • 124
    • 0036764799 scopus 로고    scopus 로고
    • Novel prostate-specific promoter derived from PSA and PSMA enhancers
    • Lee, SJ, Kim, HS, Yu, R, Lee, K, Gardner, TA, Jung, C et al. (2002). Novel prostate-specific promoter derived from PSA and PSMA enhancers. Mol Ther 6: 415-421.
    • (2002) Mol Ther , vol.6 , pp. 415-421
    • Lee, S.J.1    Kim, H.S.2    Yu, R.3    Lee, K.4    Gardner, T.A.5    Jung, C.6
  • 125
    • 0035881263 scopus 로고    scopus 로고
    • A conditional replication-competent adenoviral vector, Ad-OC-E1a, to cotarget prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis
    • Matsubara, S, Wada, Y, Gardner, TA, Egawa, M, Park, MS, Hsieh, CL et al. (2001). A conditional replication-competent adenoviral vector, Ad-OC-E1a, to cotarget prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis. Cancer Res 61: 6012-6019.
    • (2001) Cancer Res , vol.61 , pp. 6012-6019
    • Matsubara, S.1    Wada, Y.2    Gardner, T.A.3    Egawa, M.4    Park, M.S.5    Hsieh, C.L.6
  • 126
    • 0035342671 scopus 로고    scopus 로고
    • The role of vitamin D in prostate cancer
    • Zhao, XY and Feldman, D (2001). The role of vitamin D in prostate cancer. Steroids 66: 293-300.
    • (2001) Steroids , vol.66 , pp. 293-300
    • Zhao, X.Y.1    Feldman, D.2
  • 127
    • 0031463720 scopus 로고    scopus 로고
    • Vitamin D inhibition of prostate adenocarcinoma growth and metastasis in the Dunning rat prostate model system
    • Getzenberg, RH, Light, BW, Lapco, PE, Konety, BR, Nangia, AK, Acierno, JS et al. (1997). Vitamin D inhibition of prostate adenocarcinoma growth and metastasis in the Dunning rat prostate model system. Urology 50: 999-1006.
    • (1997) Urology , vol.50 , pp. 999-1006
    • Getzenberg, R.H.1    Light, B.W.2    Lapco, P.E.3    Konety, B.R.4    Nangia, A.K.5    Acierno, J.S.6
  • 128
    • 20144387357 scopus 로고    scopus 로고
    • Gene therapy for prostate cancer by controlling adenovirus E1a and E4 gene expression with PSES enhancer
    • Li, X, Zhang, YP, Kim, HS, Bae, KH, Stantz, KM, Lee, SJ et al. (2005). Gene therapy for prostate cancer by controlling adenovirus E1a and E4 gene expression with PSES enhancer. Cancer Res 65: 1941-1951.
    • (2005) Cancer Res , vol.65 , pp. 1941-1951
    • Li, X.1    Zhang, Y.P.2    Kim, H.S.3    Bae, K.H.4    Stantz, K.M.5    Lee, S.J.6
  • 129
    • 0037457032 scopus 로고    scopus 로고
    • Intratumoral spread of wild-type adenovirus is limited after local injection of human xenograft tumors: Virus persists and spreads systemically at late time points
    • Sauthoff, H, Hu, J, Maca, C, Goldman, M, Heitner, S, Yee, H et al. (2003). Intratumoral spread of wild-type adenovirus is limited after local injection of human xenograft tumors: Virus persists and spreads systemically at late time points. Hum Gene Ther 14: 425-433.
    • (2003) Hum Gene Ther , vol.14 , pp. 425-433
    • Sauthoff, H.1    Hu, J.2    Maca, C.3    Goldman, M.4    Heitner, S.5    Yee, H.6
  • 130
    • 0034917855 scopus 로고    scopus 로고
    • Wild-type adenovirus decreases tumor xenograft growth, but despite viral persistence complete tumor responses are rarely achieved-deletion of the viral E1b-19-kD gene increases the viral oncolytic effect
    • Harrison, D, Sauthoff, H, Heitner, S, Jagirdar, J, Rom, WN and Hay, JG (2001). Wild-type adenovirus decreases tumor xenograft growth, but despite viral persistence complete tumor responses are rarely achieved-deletion of the viral E1b-19-kD gene increases the viral oncolytic effect. Hum Gene Ther 12: 1323-1332.
    • (2001) Hum Gene Ther , vol.12 , pp. 1323-1332
    • Harrison, D.1    Sauthoff, H.2    Heitner, S.3    Jagirdar, J.4    Rom, W.N.5    Hay, J.G.6
  • 131
    • 20744442757 scopus 로고    scopus 로고
    • Effect of hypoxia on Ad5 infection, transgene expression and replication
    • Shen, BH and Hermiston, TW (2005). Effect of hypoxia on Ad5 infection, transgene expression and replication. Gene Ther 12: 902-910.
    • (2005) Gene Ther , vol.12 , pp. 902-910
    • Shen, B.H.1    Hermiston, T.W.2
  • 132
    • 20744460916 scopus 로고    scopus 로고
    • Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression
    • Pipiya, T, Sauthoff, H, Huang, YQ, Chang, B, Cheng, J, Heitner, S et al. (2005). Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression. Gene Ther 12: 911-917.
    • (2005) Gene Ther , vol.12 , pp. 911-917
    • Pipiya, T.1    Sauthoff, H.2    Huang, Y.Q.3    Chang, B.4    Cheng, J.5    Heitner, S.6
  • 133
    • 0030003101 scopus 로고    scopus 로고
    • The E3-11.6-kDa adenovirus death protein (ADP) is required for efficient cell death: Characterization of cells infected with adp mutants
    • Tollefson, AE, Ryerse, JS, Scaria, A, Hermiston, TW and Wold, WS (1996). The E3-11.6-kDa adenovirus death protein (ADP) is required for efficient cell death: Characterization of cells infected with adp mutants. Virology 220: 152-162.
    • (1996) Virology , vol.220 , pp. 152-162
    • Tollefson, A.E.1    Ryerse, J.S.2    Scaria, A.3    Hermiston, T.W.4    Wold, W.S.5
  • 134
    • 0035100867 scopus 로고    scopus 로고
    • Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy
    • Doronin, K, Kuppuswamy, M, Toth, K, Tollefson, AE, Krajcsi, P, Krougliak, V et al. (2001). Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy. J Virol 75: 3314-3324.
    • (2001) J Virol , vol.75 , pp. 3314-3324
    • Doronin, K.1    Kuppuswamy, M.2    Toth, K.3    Tollefson, A.E.4    Krajcsi, P.5    Krougliak, V.6
  • 135
    • 14644414207 scopus 로고    scopus 로고
    • Cotargeting tumor and tumor endothelium effectively inhibits the growth of human prostate cancer in adenovirus-mediated antiangiogenesis and oncolysis combination therapy
    • Jin, F, Xie, Z, Kuo, CJ, Chung, LW and Hsieh, CL (2005). Cotargeting tumor and tumor endothelium effectively inhibits the growth of human prostate cancer in adenovirus-mediated antiangiogenesis and oncolysis combination therapy. Cancer Gene Ther 12: 257-267.
    • (2005) Cancer Gene Ther , vol.12 , pp. 257-267
    • Jin, F.1    Xie, Z.2    Kuo, C.J.3    Chung, L.W.4    Hsieh, C.L.5
  • 136
    • 20144366573 scopus 로고    scopus 로고
    • Effective gene-virotherapy for complete eradication of tumor mediated by the combination of hTRAIL (TNFSF10) and plasminogen k5
    • Liu, XY, Qiu, SB, Zou, WG, Pei, ZF, Gu, JF, Luo, CX et al. (2005). Effective gene-virotherapy for complete eradication of tumor mediated by the combination of hTRAIL (TNFSF10) and plasminogen k5. Mol Ther 11: 531-541.
    • (2005) Mol Ther , vol.11 , pp. 531-541
    • Liu, X.Y.1    Qiu, S.B.2    Zou, W.G.3    Pei, Z.F.4    Gu, J.F.5    Luo, C.X.6
  • 137
    • 0032502844 scopus 로고    scopus 로고
    • Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo
    • Uckert, W, Kammertons, T, Haack, K, Qin, Z, Gebert, J, Schendel, DJ et al. (1998). Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo. Hum Gene Ther 9 855-865.
    • (1998) Hum Gene Ther , vol.9 , pp. 855-865
    • Uckert, W.1    Kammertons, T.2    Haack, K.3    Qin, Z.4    Gebert, J.5    Schendel, D.J.6
  • 138
    • 0010349948 scopus 로고    scopus 로고
    • Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model
    • Freytag, SO, Paielli, D, Wing, M, Rogulski, K, Brown, S, Kolozsvary, A et al. (2002). Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model. Int J Radiat Oncol Biol Phys 54: 873-885.
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 873-885
    • Freytag, S.O.1    Paielli, D.2    Wing, M.3    Rogulski, K.4    Brown, S.5    Kolozsvary, A.6
  • 139
    • 0033402277 scopus 로고    scopus 로고
    • Efficacy of adenovirus-mediated CD/5-FC and HSV-1 thymidine kinase/ganciclovir suicide gene therapies concomitant with p53 gene therapy
    • Xie, Y, Gilbert, JD, Kim, JH and Freytag, SO (1999). Efficacy of adenovirus-mediated CD/5-FC and HSV-1 thymidine kinase/ganciclovir suicide gene therapies concomitant with p53 gene therapy. Clin Cancer Res 5: 4224-4232.
    • (1999) Clin Cancer Res , vol.5 , pp. 4224-4232
    • Xie, Y.1    Gilbert, J.D.2    Kim, J.H.3    Freytag, S.O.4
  • 140
    • 23844482747 scopus 로고    scopus 로고
    • Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model
    • Ali, S, King, GD, Curtin, JF, Candolfi, M, Xiong, W, Liu, C et al. (2005). Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model. Cancer Res 65: 7194-7204.
    • (2005) Cancer Res , vol.65 , pp. 7194-7204
    • Ali, S.1    King, G.D.2    Curtin, J.F.3    Candolfi, M.4    Xiong, W.5    Liu, C.6
  • 141
    • 0032503659 scopus 로고    scopus 로고
    • A novel three-pronged approach to kill cancer cells selectively: Concomitant viral, double suicide gene, and radiotherapy
    • Freytag, SO, Rogulski, KR, Paielli, DL, Gilbert, JD and Kim, JH (1998). A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy. Hum Gene Ther 9: 1323-1333.
    • (1998) Hum Gene Ther , vol.9 , pp. 1323-1333
    • Freytag, S.O.1    Rogulski, K.R.2    Paielli, D.L.3    Gilbert, J.D.4    Kim, J.H.5
  • 142
    • 0028032719 scopus 로고
    • Selective enhancement by an antiviral agent of the radiation-induced cell killing of human glioma cells transduced with HSV-tk gene
    • Kim, JH, Kim, SH, Brown, SL and Freytag, SO (1994). Selective enhancement by an antiviral agent of the radiation-induced cell killing of human glioma cells transduced with HSV-tk gene. Cancer Res 54: 6053-6056.
    • (1994) Cancer Res , vol.54 , pp. 6053-6056
    • Kim, J.H.1    Kim, S.H.2    Brown, S.L.3    Freytag, S.O.4
  • 143
    • 0030052050 scopus 로고    scopus 로고
    • Radiosensitization by 5-fluorocytosine of human colorectal carcinoma cells in culture transduced with cytosine deaminase gene
    • Khil, MS, Kim, JH, Mullen, CA, Kim, SH and Freytag, SO (1996). Radiosensitization by 5-fluorocytosine of human colorectal carcinoma cells in culture transduced with cytosine deaminase gene. Clin Cancer Res 2: 53-57.
    • (1996) Clin Cancer Res , vol.2 , pp. 53-57
    • Khil, M.S.1    Kim, J.H.2    Mullen, C.A.3    Kim, S.H.4    Freytag, S.O.5
  • 144
    • 10744227813 scopus 로고    scopus 로고
    • Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer
    • Freytag, SO, Stricker, H, Pegg, J, Paielli, D, Pradhan, DG, Peabody, J et al. (2003). Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer. Cancer Res 63: 7497-7506.
    • (2003) Cancer Res , vol.63 , pp. 7497-7506
    • Freytag, S.O.1    Stricker, H.2    Pegg, J.3    Paielli, D.4    Pradhan, D.G.5    Peabody, J.6
  • 145
    • 0037429003 scopus 로고    scopus 로고
    • Phase I dose escalation clinical trial of adenovirus vector carrying osteocalcin promoter-driven herpes simplex virus thymidine kinase in localized and metastatic hormone-refractory prostate cancer
    • Kubo, H, Gardner, TA, Wada, Y, Koeneman, KS, Gotoh, A, Yang, L et al. (2003). Phase I dose escalation clinical trial of adenovirus vector carrying osteocalcin promoter-driven herpes simplex virus thymidine kinase in localized and metastatic hormone-refractory prostate cancer. Hum Gene Ther 14: 227-241.
    • (2003) Hum Gene Ther , vol.14 , pp. 227-241
    • Kubo, H.1    Gardner, T.A.2    Wada, Y.3    Koeneman, K.S.4    Gotoh, A.5    Yang, L.6
  • 146
    • 0036341381 scopus 로고    scopus 로고
    • Visualization of advanced human prostate cancer lesions in living mice by a targeted gene transfer vector and optical imaging
    • Adams, JY, Johnson, M, Sato, M, Berger, F, Gambhir, SS, Carey, M et al. (2002). Visualization of advanced human prostate cancer lesions in living mice by a targeted gene transfer vector and optical imaging. Nat Med 8: 891-897.
    • (2002) Nat Med , vol.8 , pp. 891-897
    • Adams, J.Y.1    Johnson, M.2    Sato, M.3    Berger, F.4    Gambhir, S.S.5    Carey, M.6
  • 147
    • 0036445786 scopus 로고    scopus 로고
    • Monogene and polygene therapy for the treatment of experimental prostate cancers by use of apoptotic genes bax and bad driven by the prostate-specific promoter ARR(2)PB
    • Zhang, Y, Yu, J, Unni, E, Shao, TC, Nan, B, Snabboon, T et al. (2002). Monogene and polygene therapy for the treatment of experimental prostate cancers by use of apoptotic genes bax and bad driven by the prostate-specific promoter ARR(2)PB. Hum Gene Ther 13: 2051-2064.
    • (2002) Hum Gene Ther , vol.13 , pp. 2051-2064
    • Zhang, Y.1    Yu, J.2    Unni, E.3    Shao, T.C.4    Nan, B.5    Snabboon, T.6
  • 148
    • 0037366192 scopus 로고    scopus 로고
    • Development of a prostate-specific promoter for gene therapy against androgen-independent prostate cancer
    • Furuhata, S, Ide, H, Miura, Y, Yoshida, T and Aoki, K (2003). Development of a prostate-specific promoter for gene therapy against androgen-independent prostate cancer. Mol Ther 7: 366-374.
    • (2003) Mol Ther , vol.7 , pp. 366-374
    • Furuhata, S.1    Ide, H.2    Miura, Y.3    Yoshida, T.4    Aoki, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.