Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity

Cancer Immunology, Immunotherapy

Volumn 55, Issue 3, 2006, Pages 347-354

  Lipinski, Kai S ^b   Pelech, Steven ^c   Mountain, Andrew ^b   Irvine, Alistair S ^b   Kraaij, Robert ^d   Bangma, Chris H ^d   Mills, Kingston H G ^a   Todryk, Stephen M ^a,e,f  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b KEELE UNIVERSITY   (United Kingdom)

^c Kinexus Bioinformatics Corporation   (Canada)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

Adenovirus; GDEPT; HSP70; Immunotherapy; Nitroreductase

Indexed keywords

5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; ADENOVIRUS VECTOR; CHAPERONE; GAMMA INTERFERON; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 25; HEAT SHOCK PROTEIN 70; INTERLEUKIN 5; NITROREDUCTASE; TUMOR ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER THERAPY; CELL DEATH; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; GENE THERAPY; IMMUNOMODULATION; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEOMICS; T LYMPHOCYTE; TUMOR CELL; TUMOR IMMUNITY; UPREGULATION;

ADENOVIRIDAE; ANIMALS; ANTINEOPLASTIC AGENTS; AZIRIDINES; CELL LINE, TUMOR; GENE THERAPY; GENETIC VECTORS; HSP70 HEAT-SHOCK PROTEINS; IMMUNOTHERAPY; MALE; MICE; MICE, INBRED C57BL; NECROSIS; NITROREDUCTASES; PROSTATIC NEOPLASMS; PROTEOMICS;

EID: 27944510121     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-005-0014-9     Document Type: Article

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