-
1
-
-
0016414528
-
Superoxide dismutases
-
Fridovich, I. (1975) Superoxide dismutases, Annu. Rev. Biochem. 44, 147-159.
-
(1975)
Annu. Rev. Biochem
, vol.44
, pp. 147-159
-
-
Fridovich, I.1
-
2
-
-
0037388067
-
Bioinorganic Chemistry Special Feature: Misfolded CuZnSOD and amyotrophic lateral sclerosis
-
Valentine, J. S., and Hart, P. J. (2003) Bioinorganic Chemistry Special Feature: Misfolded CuZnSOD and amyotrophic lateral sclerosis, Proc. Natl. Acad. Sci. U.S.A. 100, 3617-3622.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 3617-3622
-
-
Valentine, J.S.1
Hart, P.J.2
-
3
-
-
0037013264
-
Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis
-
Hayward, L. J., Rodriguez, J. A., Kim, J. W., Tiwari, A., Goto, J. J., Cabelli, D. E., Valentine, J. S., and Brown, R. H., Jr. (2002) Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis, J. Biol. Chem. 277, 15923-15931.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 15923-15931
-
-
Hayward, L.J.1
Rodriguez, J.A.2
Kim, J.W.3
Tiwari, A.4
Goto, J.J.5
Cabelli, D.E.6
Valentine, J.S.7
Brown Jr., R.H.8
-
4
-
-
0037013224
-
familial amyotrophic lateral sclerosis-associated mutations decrease the thermal stability of distinctly metallated species of human copper/ zinc superoxide dismutase
-
Rodriguez, J. A., Valentine, J. S., Eggers, D. K., Roe, J. A., Tiwari, A., Robert H. B., Jr. and Hayward, L. J. (2002) familial amyotrophic lateral sclerosis-associated mutations decrease the thermal stability of distinctly metallated species of human copper/ zinc superoxide dismutase, J. Biol. Chem. 277, 15932-15937.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 15932-15937
-
-
Rodriguez, J.A.1
Valentine, J.S.2
Eggers, D.K.3
Roe, J.A.4
Tiwari, A.5
Robert Jr., H.B.6
Hayward, L.J.7
-
5
-
-
0037458564
-
Familial amyotrophic lateral sclerosis mutants of copper/zinc superoxide dismutase are susceptible to disulfide reduction
-
Tiwari, A., and Hayward, L. J. (2003) Familial amyotrophic lateral sclerosis mutants of copper/zinc superoxide dismutase are susceptible to disulfide reduction, J. Biol. Chem. 278, 5984-5992.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 5984-5992
-
-
Tiwari, A.1
Hayward, L.J.2
-
6
-
-
22244479388
-
Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis
-
Valentine, J. S., Doucette, P. A., and Potter, S. Z. (2005) Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis, Annu. Rev. Biochem. 74, 563-593.
-
(2005)
Annu. Rev. Biochem
, vol.74
, pp. 563-593
-
-
Valentine, J.S.1
Doucette, P.A.2
Potter, S.Z.3
-
7
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
Bruijn, L. I., Miller, T. M., and Cleveland, D. W. (2004) Unraveling the mechanisms involved in motor neuron degeneration in ALS, Annu. Rev. Neurosci. 27, 723-749.
-
(2004)
Annu. Rev. Neurosci
, vol.27
, pp. 723-749
-
-
Bruijn, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
8
-
-
0035516124
-
From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
-
Cleveland, D. W., and Rothstein, J. D. (2001) From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS, Nat. Rev. Neurosci. 2, 806-819.
-
(2001)
Nat. Rev. Neurosci
, vol.2
, pp. 806-819
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
9
-
-
0027426169
-
Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase
-
Deng, H. X., Hentati, A., Tainer, J. A., Iqbal, Z., Cayabyab, A., Huang, W. Y., Getzoff, E. D., Hu, P., Herzfeldt, B., Roos, R. P., Warner, C., Deng, G., Soriano, E., Smyth, C., Parge, H. E., Ahmed, A., Roses, A. D., Hallewell, R. A., Pericak-Vance, M. A., and Siddique, T. (1993) Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase, Science 261, 1047-1051.
-
(1993)
Science
, vol.261
, pp. 1047-1051
-
-
Deng, H.X.1
Hentati, A.2
Tainer, J.A.3
Iqbal, Z.4
Cayabyab, A.5
Huang, W.Y.6
Getzoff, E.D.7
Hu, P.8
Herzfeldt, B.9
Roos, R.P.10
Warner, C.11
Deng, G.12
Soriano, E.13
Smyth, C.14
Parge, H.E.15
Ahmed, A.16
Roses, A.D.17
Hallewell, R.A.18
Pericak-Vance, M.A.19
Siddique, T.20
more..
-
10
-
-
0027401203
-
-
Rosen, D. R., Siddique, T., Patterson, D., Figlewicz, D. A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J. P., Deng, H. X., Rahmani, Z., Krizus, A., McKenna-Yasek, D., Cayabyab, A., Gaston, S. M., Berger, R., Tazni, R. E., Halperin, J. J., Herzfeldt, B., van der Bergh, R., Huang, W. Y. T., Bird, Deng, G., Mulder, D. W., Smyth, C., Laing, N. G., Soriano, E., Pericak-Vance, M. A., Haines, J., Roulean, G. A., Gusella, J. S., Harvitz, H. R., and Brown, R. H., Jr. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis, Nature 362, 59-62.
-
Rosen, D. R., Siddique, T., Patterson, D., Figlewicz, D. A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J. P., Deng, H. X., Rahmani, Z., Krizus, A., McKenna-Yasek, D., Cayabyab, A., Gaston, S. M., Berger, R., Tazni, R. E., Halperin, J. J., Herzfeldt, B., van der Bergh, R., Huang, W. Y. T., Bird, Deng, G., Mulder, D. W., Smyth, C., Laing, N. G., Soriano, E., Pericak-Vance, M. A., Haines, J., Roulean, G. A., Gusella, J. S., Harvitz, H. R., and Brown, R. H., Jr. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis, Nature 362, 59-62.
-
-
-
-
11
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu.Zn superoxide dismutase mutation
-
Gurney, M. E., Pu, H., Chiu, A. Y., Dal Canto, M. C., Polchow, C. Y., Alexander, D. D., Caliendo, J., Hentati, A., Kwon, Y. W., and Deng, H. X. (1994) Motor neuron degeneration in mice that express a human Cu.Zn superoxide dismutase mutation, Science 264, 1772-1775.
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.X.10
-
12
-
-
33645225597
-
Pathogenic superoxide dismutase structure, folding, aggregation and turnover
-
Hart, P. J. (2006) Pathogenic superoxide dismutase structure, folding, aggregation and turnover, Curr. Opin. Chem. Biol. 10, 131-138.
-
(2006)
Curr. Opin. Chem. Biol
, vol.10
, pp. 131-138
-
-
Hart, P.J.1
-
13
-
-
33749056809
-
ALS: A disease of motor neurons and their nonneuronal neighbors
-
Boillee, S., Velde, C. V., and Cleveland, D. W. (2006) ALS: a disease of motor neurons and their nonneuronal neighbors, Neuron 52, 39-59.
-
(2006)
Neuron 52
, pp. 39-59
-
-
Boillee, S.1
Velde, C.V.2
Cleveland, D.W.3
-
14
-
-
23044431627
-
Destabilization of apoprotein is insufficient to explain Cu,Zn-superoxide dismutase-linked ALS pathogenesis
-
Rodriguez, J. A., Shaw, B. F., Durazo, A., Sohn, H., Doucette, P. A., Nersissian, A. M., Fauli, K. F., Eggers, D. K., Tiwari, A., Hayward, L. J., and Valentine, J. S. (2005) Destabilization of apoprotein is insufficient to explain Cu,Zn-superoxide dismutase-linked ALS pathogenesis, Proc. Natl. Acad. Sci. U.S.A. 102, 10516-10521.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 10516-10521
-
-
Rodriguez, J.A.1
Shaw, B.F.2
Durazo, A.3
Sohn, H.4
Doucette, P.A.5
Nersissian, A.M.6
Fauli, K.F.7
Eggers, D.K.8
Tiwari, A.9
Hayward, L.J.10
Valentine, J.S.11
-
15
-
-
0037168643
-
Common denominator of Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis: Decreased stability of the apo state
-
Lindberg, M. J., Tibell, L., and Oliveberg, M. (2002) Common denominator of Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis: decreased stability of the apo state, Proc. Natl. Acad. Sci. U.S.A. 99, 16607-16612.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 16607-16612
-
-
Lindberg, M.J.1
Tibell, L.2
Oliveberg, M.3
-
16
-
-
0037795635
-
Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro
-
Stathopulos, P. B., Rumfeldt, J. A. O., Scholz, G. A., Irani, R. A., Frey, H. E., Hallewell, R. A., Lepock, J. R., and Metering, E. M. (2003) Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro, Proc. Natl. Acad. Sci. U.S.A. 100, 7021-7026.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 7021-7026
-
-
Stathopulos, P.B.1
Rumfeldt, J.A.O.2
Scholz, G.A.3
Irani, R.A.4
Frey, H.E.5
Hallewell, R.A.6
Lepock, J.R.7
Metering, E.M.8
-
17
-
-
2442624720
-
Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis
-
Rakhit, R., Crow, J. P., Lepock, J. R., Kondejewski, L. H., Cashman, N. R., and Chakrabartty, A. (2004) Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis, J. Biol. Chem. 279, 15499-15504.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 15499-15504
-
-
Rakhit, R.1
Crow, J.P.2
Lepock, J.R.3
Kondejewski, L.H.4
Cashman, N.R.5
Chakrabartty, A.6
-
18
-
-
15744398884
-
Oxidative modifications and aggregation of Cu,-Zn-superoxide dismutase associated with Alzheimer and Parkinson diseases
-
Choi, J., Rees, H. D., Weintraub, S. T., Levey, A. I., Chin, L.-S., and Li, L. (2005) Oxidative modifications and aggregation of Cu,-Zn-superoxide dismutase associated with Alzheimer and Parkinson diseases, J. Biol. Chem. 280, 11648-11655.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 11648-11655
-
-
Choi, J.1
Rees, H.D.2
Weintraub, S.T.3
Levey, A.I.4
Chin, L.-S.5
Li, L.6
-
19
-
-
0032544674
-
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1
-
Bruijin, L. I., Houseweart, M. K., Kato, S., Anderson, K. L., Anderson, S. D., Ohama, E., Reaume, A. G., Scott, R. W., and Cleveland, D. W. (1998) Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1, Science 281, 1851-1854.
-
(1998)
Science
, vol.281
, pp. 1851-1854
-
-
Bruijin, L.I.1
Houseweart, M.K.2
Kato, S.3
Anderson, K.L.4
Anderson, S.D.5
Ohama, E.6
Reaume, A.G.7
Scott, R.W.8
Cleveland, D.W.9
-
21
-
-
0347357617
-
Protein folding and misfolding
-
Dobson, CM. (2003) Protein folding and misfolding, Nature 426, 884-890.
-
(2003)
Nature
, vol.426
, pp. 884-890
-
-
Dobson, C.M.1
-
22
-
-
0036076642
-
Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site
-
Wang, J., Xu, G., Gonzales, V., Coonfielld, M., Fromholt, D., Copeland, N. G., Jenkins, N. A., and Borchelt, D. R. (2002) Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site, Neurobiol. Dis. 10, 128-138.
-
(2002)
Neurobiol. Dis
, vol.10
, pp. 128-138
-
-
Wang, J.1
Xu, G.2
Gonzales, V.3
Coonfielld, M.4
Fromholt, D.5
Copeland, N.G.6
Jenkins, N.A.7
Borchelt, D.R.8
-
23
-
-
0033749379
-
Formation of high molecular weight complexes of mutant Cu,Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis
-
Johnston, J. A., Dalton, M. J., Gurney, M. E., and Kopito, R. R. (2000) Formation of high molecular weight complexes of mutant Cu,Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis, Proc. Natl. Acad. Sci. U.S.A. 97, 12571-12576.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 12571-12576
-
-
Johnston, J.A.1
Dalton, M.J.2
Gurney, M.E.3
Kopito, R.R.4
-
24
-
-
27644596641
-
Opinion: What is the role of protein aggregation in neurodegeneration?
-
Ross, C. A., and Poirier, M. A. (2005) Opinion: what is the role of protein aggregation in neurodegeneration?, Nat. Rev. Mol. Cell Biol. 6, 891-898.
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 891-898
-
-
Ross, C.A.1
Poirier, M.A.2
-
25
-
-
33644899679
-
Intracellular conformational alterations of mutant SOD1 and the implications for fALS-associated SOD1 mutant induced motor neuron cell death
-
Zhang, F., and Zhu, H. (2006) Intracellular conformational alterations of mutant SOD1 and the implications for fALS-associated SOD1 mutant induced motor neuron cell death, Biochim. Biophys. Acta. 1760, 404-414.
-
(2006)
Biochim. Biophys. Acta
, vol.1760
, pp. 404-414
-
-
Zhang, F.1
Zhu, H.2
-
26
-
-
0042736853
-
ALS Mutants of human superoxide dismutase form fibrous aggregates via framework destabilization
-
DiDonato, M., Craig, L., Huff, M. E., Thayer, M. M., Cardoso, R. M. F., Kassmann, C. J., Lo, T. P., Bruns, C. K., Powers, E. T., Kelly, J. W., Getzoff, E. D., and Tainer, J. A. (2003) ALS Mutants of human superoxide dismutase form fibrous aggregates via framework destabilization, J. Mol. Biol. 332, 601-615.
-
(2003)
J. Mol. Biol
, vol.332
, pp. 601-615
-
-
DiDonato, M.1
Craig, L.2
Huff, M.E.3
Thayer, M.M.4
Cardoso, R.M.F.5
Kassmann, C.J.6
Lo, T.P.7
Bruns, C.K.8
Powers, E.T.9
Kelly, J.W.10
Getzoff, E.D.11
Tainer, J.A.12
-
27
-
-
6344277909
-
The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis
-
Khare, S. D., Caplow, M., and Dokholyan, N. V. (2004) The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis, Proc. Natl. Acad. Sci. U.S.A. 101, 15094-15099.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 15094-15099
-
-
Khare, S.D.1
Caplow, M.2
Dokholyan, N.V.3
-
28
-
-
33745726690
-
Copper homeostasis and neurodegenerative disorders (Alzheimer's, Prion, and Parkinson's diseases and amyotrophic lateral sclerosis)
-
Gaggelli, E., Kozlowski, H., Valennsin, D., and Valensin, G. (2006) Copper homeostasis and neurodegenerative disorders (Alzheimer's, Prion, and Parkinson's diseases and amyotrophic lateral sclerosis), Chem. Rev. 106, 1995-2044.
-
(2006)
Chem. Rev
, vol.106
, pp. 1995-2044
-
-
Gaggelli, E.1
Kozlowski, H.2
Valennsin, D.3
Valensin, G.4
-
29
-
-
33748340448
-
Divalent-metal-dependent nucleolytic activity of Cu, Zn superoxide dismutase
-
Jiang, W., Shen. T., Han. Y., Pan, Q., and Liu, C. (2006) Divalent-metal-dependent nucleolytic activity of Cu, Zn superoxide dismutase, J. Biol. Inorg. Chem. 11, 835-848.
-
(2006)
J. Biol. Inorg. Chem
, vol.11
, pp. 835-848
-
-
Jiang, W.1
Shen, T.2
Han, Y.3
Pan, Q.4
Liu, C.5
-
30
-
-
33847363183
-
Roles of exogenous divalent metals in the nucleolytic activity of Cu,Zn superoxide dismutase
-
Jiang, W., Han Y., Pan, Q., Shen, T., Liu, C. (2007) Roles of exogenous divalent metals in the nucleolytic activity of Cu,Zn superoxide dismutase, J. Inorg. Biochem. 101, 667-677.
-
(2007)
J. Inorg. Biochem
, vol.101
, pp. 667-677
-
-
Jiang, W.1
Han, Y.2
Pan, Q.3
Shen, T.4
Liu, C.5
-
31
-
-
0038442784
-
Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS
-
Elam, J. S., Taylor, A. B., Strange, R., Antonyuk, S., Doucette, P. A., Rodriguez, J. A., Hasnain, S. S., Hayward, L. J., Valentine, J. S., Yeates, T. O., and Hart, P. J. (2003) Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS, Nat. Struct. Biol. 10, 461-467.
-
(2003)
Nat. Struct. Biol
, vol.10
, pp. 461-467
-
-
Elam, J.S.1
Taylor, A.B.2
Strange, R.3
Antonyuk, S.4
Doucette, P.A.5
Rodriguez, J.A.6
Hasnain, S.S.7
Hayward, L.J.8
Valentine, J.S.9
Yeates, T.O.10
Hart, P.J.11
-
32
-
-
2142761528
-
-
Ray, S. S., Nowak, R. J., Strokovich, K., Brown, R. H., Jr., WaIz, T., and Lansbury, P. T., Jr. (2004) An intersubunit disulfide bond prevents in vitro aggregation of a superoxide dismutase-1 mutant linked to familial amytrophic lateral sclerosis, Biochemistry 43, 4899-4905.
-
Ray, S. S., Nowak, R. J., Strokovich, K., Brown, R. H., Jr., WaIz, T., and Lansbury, P. T., Jr. (2004) An intersubunit disulfide bond prevents in vitro aggregation of a superoxide dismutase-1 mutant linked to familial amytrophic lateral sclerosis, Biochemistry 43, 4899-4905.
-
-
-
-
33
-
-
0344495441
-
Cu/Zn superoxide dismutase can form pore-like structures
-
Chung, J., Xu, G., De Beus, M. D., Ryu, C. Y., Cho, K., and Colon, W. (2003) Cu/Zn superoxide dismutase can form pore-like structures, Biophys. Res. Commun. 312, 873-876.
-
(2003)
Biophys. Res. Commun
, vol.312
, pp. 873-876
-
-
Chung, J.1
Xu, G.2
De Beus, M.D.3
Ryu, C.Y.4
Cho, K.5
Colon, W.6
-
34
-
-
0025095410
-
Sensitive enzyme immunoassay for human Cu/Zn superoxide dismutase
-
Kurobe, N., Suzuki, F., Okajima, K., and Kato, K. (1990) Sensitive enzyme immunoassay for human Cu/Zn superoxide dismutase, Clin. Chim. Acta 187, 11-20.
-
(1990)
Clin. Chim. Acta
, vol.187
, pp. 11-20
-
-
Kurobe, N.1
Suzuki, F.2
Okajima, K.3
Kato, K.4
-
35
-
-
33644986099
-
Mechanisms of protein assembly: Lessons from minimalist models
-
Levy, Y., and Onuchic, J. N. (2006) Mechanisms of protein assembly: lessons from minimalist models. Acc. Chem. Res. 39, 135-142.
-
(2006)
Acc. Chem. Res
, vol.39
, pp. 135-142
-
-
Levy, Y.1
Onuchic, J.N.2
-
36
-
-
26444542945
-
Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: AlphaB-crystallin modulates aggregation
-
Wang, J., Xu, G., Li, H., Gonzales, V., Fromholt, D., Karch, C., Copeland, N. G., Jenkins, N. A., and Borchelt, D. R. (2005) Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation, Hum. Mol. Genet. 14, 2335-2347.
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 2335-2347
-
-
Wang, J.1
Xu, G.2
Li, H.3
Gonzales, V.4
Fromholt, D.5
Karch, C.6
Copeland, N.G.7
Jenkins, N.A.8
Borchelt, D.R.9
-
37
-
-
3242701496
-
Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria
-
Liu, J., Lillo, C., Jonsson, A., Velde, C. V., Ward, C. M., Miller. T. M., Subramaniam, J. R., Rothstein, J. D., Marklund, S., Andersen, P. M., Brannstrom, T., Gredal, O., Wong, P. C., Williams, D. S., and Cleveland, D. W. (2004) Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria, Neuron 43, 5-17.
-
(2004)
Neuron
, vol.43
, pp. 5-17
-
-
Liu, J.1
Lillo, C.2
Jonsson, A.3
Velde, C.V.4
Ward, C.M.5
Miller, T.M.6
Subramaniam, J.R.7
Rothstein, J.D.8
Marklund, S.9
Andersen, P.M.10
Brannstrom, T.11
Gredal, O.12
Wong, P.C.13
Williams, D.S.14
Cleveland, D.W.15
-
38
-
-
20444415277
-
Unsaturated fatty acids induce cytotoxic aggregate formation of amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutants
-
Kim, Y.-J., Nakatomi, R., Akagi, T., Hashikawa, T., and Takahashi, R. (2005) Unsaturated fatty acids induce cytotoxic aggregate formation of amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutants, J. Biol. Chem. 280, 21515-21521.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 21515-21521
-
-
Kim, Y.-J.1
Nakatomi, R.2
Akagi, T.3
Hashikawa, T.4
Takahashi, R.5
-
39
-
-
0031719571
-
RNA sequestration to pathological lesions of neurodegenerative diseases
-
Ginsberg, S. D., Galvin, J. E., Chiu, T. S., Lee, V. M., Masliah, E., and Trojanowski, J. Q. (1998) RNA sequestration to pathological lesions of neurodegenerative diseases, Acta Neuropathol. 96, 487-494.
-
(1998)
Acta Neuropathol
, vol.96
, pp. 487-494
-
-
Ginsberg, S.D.1
Galvin, J.E.2
Chiu, T.S.3
Lee, V.M.4
Masliah, E.5
Trojanowski, J.Q.6
-
40
-
-
0036970469
-
DNA-induced partial unfolding of prion protein leads to its polymerisation to amyloid
-
Nandi, P. K., Leclerc, E., Nicole, J.-C., and Takahashi, M. (2002) DNA-induced partial unfolding of prion protein leads to its polymerisation to amyloid, J. Mol. Biol. 322, 153-161.
-
(2002)
J. Mol. Biol
, vol.322
, pp. 153-161
-
-
Nandi, P.K.1
Leclerc, E.2
Nicole, J.-C.3
Takahashi, M.4
-
41
-
-
8544264563
-
Double-stranded DNA stimulates the fibrillation of alpha-synuclein in vitro and is associated with the mature fibrils: An electron microscopy study
-
Cherny, D., Hoyer, W., Subramaniam, V., and Jovin, T. M. (2004) Double-stranded DNA stimulates the fibrillation of alpha-synuclein in vitro and is associated with the mature fibrils: an electron microscopy study, J. Mol. Biol. 344, 929-938.
-
(2004)
J. Mol. Biol
, vol.344
, pp. 929-938
-
-
Cherny, D.1
Hoyer, W.2
Subramaniam, V.3
Jovin, T.M.4
-
42
-
-
33750353368
-
Nature and significance of the interactions between amyloid fibrils and biological polyelectrolytes
-
Calamai, M., Kumita, J. R., Mifsud, J., Parrini, C., Ramazzotti, M., Ramponi, G., Taddei, N., Chiti, F., and Dobson, C. M. (2006) Nature and significance of the interactions between amyloid fibrils and biological polyelectrolytes, Biochemistry 45, 12806-12815.
-
(2006)
Biochemistry
, vol.45
, pp. 12806-12815
-
-
Calamai, M.1
Kumita, J.R.2
Mifsud, J.3
Parrini, C.4
Ramazzotti, M.5
Ramponi, G.6
Taddei, N.7
Chiti, F.8
Dobson, C.M.9
-
43
-
-
0142184333
-
RNA molecules stimulate prion protein conversion
-
Deleault, N. R., Lucassen, R. W., and Supattapone, S. (2003) RNA molecules stimulate prion protein conversion, Nature 425, 717-720.
-
(2003)
Nature
, vol.425
, pp. 717-720
-
-
Deleault, N.R.1
Lucassen, R.W.2
Supattapone, S.3
-
44
-
-
0035966046
-
DNA converts cellular prion protein into the β-sheet conformation and inhibits prion peptide aggregation
-
Cordeiro, Y., Machado, F., Juliano, L., Juliano, M. A., Brentani, R. R., Foguel, D., and Silva, J. L. (2001) DNA converts cellular prion protein into the β-sheet conformation and inhibits prion peptide aggregation, J. Biol. Chem. 276, 49400-49409.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 49400-49409
-
-
Cordeiro, Y.1
Machado, F.2
Juliano, L.3
Juliano, M.A.4
Brentani, R.R.5
Foguel, D.6
Silva, J.L.7
-
45
-
-
0017330664
-
Nuclear magnetic resonance and chemical modification studies of bovine erythrocyte superoxide dismutase: Evidence for zinc-promoted organization of the active site structure
-
Lippard, S. J., Burger, A. B, Ugurbil, K., Pantoliano, M. W., and Valentine, J. S. (1977) Nuclear magnetic resonance and chemical modification studies of bovine erythrocyte superoxide dismutase: evidence for zinc-promoted organization of the active site structure, Biochemistry 16, 1136-1141.
-
(1977)
Biochemistry
, vol.16
, pp. 1136-1141
-
-
Lippard, S.J.1
Burger, A.B.2
Ugurbil, K.3
Pantoliano, M.W.4
Valentine, J.S.5
-
46
-
-
0014691242
-
Superoxide dismutase. An enzymie function for erythrocuprein (hemocuprein)
-
McCord, J. M., and Fridovich, I. (1969) Superoxide dismutase. An enzymie function for erythrocuprein (hemocuprein), J. Biol. Chem. 244, 6049-6055.
-
(1969)
J. Biol. Chem
, vol.244
, pp. 6049-6055
-
-
McCord, J.M.1
Fridovich, I.2
-
47
-
-
0347155578
-
Oxidation-induced misfolding and aggregation of superoxide dismutase and its implications for amyotrophic lateral sclerosis
-
Rakhit, R., Cunningham, P., Furtos-Matei, A., Dahan, S., Qi, X. F., Crow, J. P., Cashman, N. R., Kondejewski, L. H., and Chakrabartty, A. (2002) Oxidation-induced misfolding and aggregation of superoxide dismutase and its implications for amyotrophic lateral sclerosis, J. Biol. Chem. 277, 47551-47556.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 47551-47556
-
-
Rakhit, R.1
Cunningham, P.2
Furtos-Matei, A.3
Dahan, S.4
Qi, X.F.5
Crow, J.P.6
Cashman, N.R.7
Kondejewski, L.H.8
Chakrabartty, A.9
-
48
-
-
33645108790
-
High-resolution atomic force microscopy of soluble Aβ342 oligomers
-
Mastrangelo, I. A., Ahmed, M., Sato, T., Liu, W., Wang, C., Hough, P., and Smith, S. O. (2006) High-resolution atomic force microscopy of soluble Aβ342 oligomers, J. Mol. Biol. 358, 106-119.
-
(2006)
J. Mol. Biol
, vol.358
, pp. 106-119
-
-
Mastrangelo, I.A.1
Ahmed, M.2
Sato, T.3
Liu, W.4
Wang, C.5
Hough, P.6
Smith, S.O.7
-
49
-
-
0041999563
-
-
1st ed, pp, China Higher Education Press, Beijing, and Springer-Verlag, Heidelberg
-
Zhao, N. M., and Zhou, H. M. (2000) Biophysics, 1st ed., pp 73-98, China Higher Education Press, Beijing, and Springer-Verlag, Heidelberg.
-
(2000)
Biophysics
, pp. 73-98
-
-
Zhao, N.M.1
Zhou, H.M.2
-
50
-
-
33846077483
-
DNA cleavage mediated by copper superoxide dismutase via two patyways
-
Han, Y., Shen, T., Jiang, W., Xia, Q., and Liu, C. (2007) DNA cleavage mediated by copper superoxide dismutase via two patyways, J. Inorg. Biochem. 101, 214-224.
-
(2007)
J. Inorg. Biochem
, vol.101
, pp. 214-224
-
-
Han, Y.1
Shen, T.2
Jiang, W.3
Xia, Q.4
Liu, C.5
-
51
-
-
34249040931
-
-
U.S. Patent 5,436,134
-
Haugland, R. P., Yue, S. T., Millard, P. J., and Roth, B. L. (1995) U.S. Patent 5,436,134.
-
(1995)
-
-
Haugland, R.P.1
Yue, S.T.2
Millard, P.J.3
Roth, B.L.4
-
52
-
-
33645408282
-
Modulating amyloid self-assembly and fibril morphology with Zn(II)
-
Dong, J., Shokes, J. E., Scott, R. A., and Lynn, D. G. (2006) Modulating amyloid self-assembly and fibril morphology with Zn(II), J. Am. Chem. Soc. 128, 3540-3542.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 3540-3542
-
-
Dong, J.1
Shokes, J.E.2
Scott, R.A.3
Lynn, D.G.4
-
53
-
-
0008444371
-
Reversible loss of metal ions from the zinc binding site of copper-zinc superoxide dismutase. The low pH transition
-
Pantoliano, M. W., McDonnell, P. J., and Valentine, J. S. (1979) Reversible loss of metal ions from the zinc binding site of copper-zinc superoxide dismutase. The low pH transition, J. Am. Chem. Soc. 101, 6454-6455.
-
(1979)
J. Am. Chem. Soc
, vol.101
, pp. 6454-6455
-
-
Pantoliano, M.W.1
McDonnell, P.J.2
Valentine, J.S.3
-
54
-
-
0016709348
-
The behavior of holo- and apo-forms of bovine superoxide dismutase at low pH
-
Fee, J. A., and Phillips, W. D. (1975) The behavior of holo- and apo-forms of bovine superoxide dismutase at low pH, Biochim. Biophys. Acta 412, 26-38.
-
(1975)
Biochim. Biophys. Acta
, vol.412
, pp. 26-38
-
-
Fee, J.A.1
Phillips, W.D.2
-
55
-
-
0033813424
-
A glimpse of a possible amyloidogenic intermediate of transthyretin
-
Liu, K., Cho, H. S., Lashuel, H. A., Kelly, J. W., and Wemmer, D. E. (2000) A glimpse of a possible amyloidogenic intermediate of transthyretin, Nat. Struct. Biol. 9, 754-757.
-
(2000)
Nat. Struct. Biol
, vol.9
, pp. 754-757
-
-
Liu, K.1
Cho, H.S.2
Lashuel, H.A.3
Kelly, J.W.4
Wemmer, D.E.5
-
56
-
-
0036240398
-
Structural properties of an amyloid precursor of β32-microglobulin
-
McParland, V. J., Kalverda, A. P., Homans, S. W., and Radford, S. E. (2002) Structural properties of an amyloid precursor of β32-microglobulin, Nat. Struct. Biol. 9, 326-331.
-
(2002)
Nat. Struct. Biol
, vol.9
, pp. 326-331
-
-
McParland, V.J.1
Kalverda, A.P.2
Homans, S.W.3
Radford, S.E.4
-
57
-
-
0030781922
-
pH-Dependent stability and conformation of the recombinant human prion protein PrP
-
Swietnicki, W., Petersen, R., Gambetti, P., and Surewicz, W. K. (1997) pH-Dependent stability and conformation of the recombinant human prion protein PrP (90-231), J. Biol. Chem. 272, 27517-27520.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 27517-27520
-
-
Swietnicki, W.1
Petersen, R.2
Gambetti, P.3
Surewicz, W.K.4
-
58
-
-
0034636977
-
Is Polyproline II Helix the Killer Conformation? A raman optical activity study of the amyloidogenic prefibrillar intermediate of human lysozyme
-
Blanch, E. W., Morozova-Roche, L. A., Cochran, D. A. E., Doig, A. J., Hecht, L., and Barron, L. D. (2000) Is Polyproline II Helix the Killer Conformation? A raman optical activity study of the amyloidogenic prefibrillar intermediate of human lysozyme, J. Mol. Biol. 301, 553-563.
-
(2000)
J. Mol. Biol
, vol.301
, pp. 553-563
-
-
Blanch, E.W.1
Morozova-Roche, L.A.2
Cochran, D.A.E.3
Doig, A.J.4
Hecht, L.5
Barron, L.D.6
-
59
-
-
0021107002
-
Electrostatic recognition between superoxide and copper, zinc superoxide dismutase
-
Getzoff, E. D., Tainer, J. A., Weiner, P. K., Kollman, P. A., Richardson, J. S., and Richardson, D. C. (1983) Electrostatic recognition between superoxide and copper, zinc superoxide dismutase, Nature 306, 287-290.
-
(1983)
Nature
, vol.306
, pp. 287-290
-
-
Getzoff, E.D.1
Tainer, J.A.2
Weiner, P.K.3
Kollman, P.A.4
Richardson, J.S.5
Richardson, D.C.6
-
60
-
-
32344448608
-
Protein aggregation and amyloidosis: Confusion of the kinds?
-
Rousseau, F., Schymkowitz, J., and Serrano, L. (2006) Protein aggregation and amyloidosis: confusion of the kinds?, Curr. Opin. Struct. Biol. 16, 118-126.
-
(2006)
Curr. Opin. Struct. Biol
, vol.16
, pp. 118-126
-
-
Rousseau, F.1
Schymkowitz, J.2
Serrano, L.3
-
61
-
-
0034700253
-
Oxidative regulation of fatty acid-induced Tau polymerization
-
Gamblin, T. C., King, M. E., Kuret, J., Berry, R. W., and Binder, L. I. (2000) Oxidative regulation of fatty acid-induced Tau polymerization, Biochemistry 39, 14203-14210.
-
(2000)
Biochemistry
, vol.39
, pp. 14203-14210
-
-
Gamblin, T.C.1
King, M.E.2
Kuret, J.3
Berry, R.W.4
Binder, L.I.5
-
62
-
-
33746095813
-
Secondary structure and interfacial aggregation of amyloid-β (1-40) on sodium dodecyl sulfate micelles
-
Rangachari, V., Reed, D. K., Moore, B. D., and Rosenberry, T. L. (2006) Secondary structure and interfacial aggregation of amyloid-β (1-40) on sodium dodecyl sulfate micelles, Biochemistry 45, 8639-8648.
-
(2006)
Biochemistry
, vol.45
, pp. 8639-8648
-
-
Rangachari, V.1
Reed, D.K.2
Moore, B.D.3
Rosenberry, T.L.4
-
63
-
-
0030590911
-
RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments
-
Kampers, T., Friedhoff, P., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (1996) RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments, FEBS Lett. 399, 344-349.
-
(1996)
FEBS Lett
, vol.399
, pp. 344-349
-
-
Kampers, T.1
Friedhoff, P.2
Biernat, J.3
Mandelkow, E.M.4
Mandelkow, E.5
-
64
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
Soto, C. (2003) Unfolding the role of protein misfolding in neurodegenerative diseases, Nat. Rev. Neurosci. 4, 49-60.
-
(2003)
Nat. Rev. Neurosci
, vol.4
, pp. 49-60
-
-
Soto, C.1
-
65
-
-
33645995764
-
Recent atomic models of amyloid fibril structure
-
Nelson, R., and Eisenberg, D. (2006) Recent atomic models of amyloid fibril structure, Curr. Opin. Struct. Biol. 16, 260-265.
-
(2006)
Curr. Opin. Struct. Biol
, vol.16
, pp. 260-265
-
-
Nelson, R.1
Eisenberg, D.2
-
66
-
-
23844471242
-
Aberrantly increased hydrophobicity shared by mutants of Cu,Zn-superoxide dismutase in familial amyotrophic lateral sclerosis
-
Tiwari, A., Xu, Z., and Hayward, L. J. (2006) Aberrantly increased hydrophobicity shared by mutants of Cu,Zn-superoxide dismutase in familial amyotrophic lateral sclerosis, J. Biol. Chem. 280, 29771-29779.
-
(2006)
J. Biol. Chem
, vol.280
, pp. 29771-29779
-
-
Tiwari, A.1
Xu, Z.2
Hayward, L.J.3
-
67
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
Arrasate, M., Mitra, S., Schweitzer, E. S., Segal, M. R., and Finkbeiner, S. (2004) Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death, Nature 431, 805-810.
-
(2004)
Nature
, vol.431
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
Schweitzer, E.S.3
Segal, M.R.4
Finkbeiner, S.5
-
68
-
-
0037388418
-
Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein
-
Taylor, J. P., Tanaka, F., Robitschek, J., Sandoval, C. M., Taye, A., Markovic-Plese, S., and Fischbeck, K. H. (2003) Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein, Hum. Mol. Genet. 12, 749-757.
-
(2003)
Hum. Mol. Genet
, vol.12
, pp. 749-757
-
-
Taylor, J.P.1
Tanaka, F.2
Robitschek, J.3
Sandoval, C.M.4
Taye, A.5
Markovic-Plese, S.6
Fischbeck, K.H.7
-
69
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini, M., Giannoni, E., Chiti, F., Baroni, F., Formigli, L., Zurdo, J., Taddei, N., Ramponi, G., Dobson, C. M., and Stefani, M. (2002) Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases, Nature 416, 507-511.
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddei, N.7
Ramponi, G.8
Dobson, C.M.9
Stefani, M.10
-
70
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., and Glabe, C. G. (2003) Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis, Science 300, 486-489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
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