DNA Converts Cellular Prion Protein into the β-Sheet Conformation and Inhibits Prion Peptide Aggregation

Journal of Biological Chemistry

Volumn 276, Issue 52, 2001, Pages 49400-49409

  Cordeiro, Yraima ^a   Machado, Filipe ^a   Juliano, Luiz ^b   Juliano, Maria Aparecida ^b   Brentani, Ricardo R ^c   Foguel, Débora ^a   Silva, Jerson L ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; DNA; DNA SEQUENCES; FLUORESCENCE; LIGHT SCATTERING; PH EFFECTS; SPECTROSCOPIC ANALYSIS;

MACROMOLECULAR COMPLEX;

PROTEINS;

CELL PROTEIN; DNA; OLIGONUCLEOTIDE; PRION PROTEIN; DNA BINDING PROTEIN; DNA BINDING PROTEINS; ISOPROTEIN; UREA;

ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; CIRCULAR DICHROISM; CREUTZFELDT JAKOB DISEASE; DNA BINDING; FLUORESCENCE POLARIZATION; FLUORESCENCE SPECTROSCOPY; LIGHT SCATTERING; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE SYNTHESIS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; ULTRAVIOLET SPECTROSCOPY; ANIMAL; CHEMISTRY; CONFORMATION; GENETICS; HUMAN; METABOLISM; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; SPECTROFLUOROMETRY; THERMODYNAMICS;

MURINAE;

ANIMAL; CIRCULAR DICHROISM; DNA; DNA-BINDING PROTEINS; HUMAN; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; PRION DISEASES; PROTEIN CONFORMATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY; PRPC PROTEINS; PRPSC PROTEINS; SPECTROMETRY, FLUORESCENCE; SUPPORT, NON-U.S. GOV'T; THERMODYNAMICS; UREA;

EID: 0035966046     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M106707200     Document Type: Article

References (60)

1. Cohen, F. E., and Prusiner, S. B. (1998) Annu. Rev. Biochem. 67, 793-819
2. Weissman, C. (1999) J. Biol. Chem. 274, 3-6
3. Caughey, B. (2000) Nat. Med. 6, 751-754
4. Will, R. G., Ironside, J. W., Zeidler, M., Cousens, S. N., Estibeiro, K., Alperovitch, A., Poser, S., Pocchiari, M., Hofman, A., and Smith, P. G. (1996) Lancet 347, 921-925
5. Prusiner, S. B. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13363-13383
6. Bons, N., Mestre-Frances, N., Belli, P., Cathala, F., Gajdusek, D. C., and Brown, P. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 4046-4051
7. Alper, T., Cramp, W. A., Haig, D. A., and Clarke, M. C. (1967) Nature 214, 764-766
8. Pan, K. H., Baldwin, M., Nguyen, J., Gasset, M., Serban, A., Groth, D., Mehlhorn, I., Huang, Z., Fletterick, J., and Cohen, F. E. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10962-10966
9. Huang, Z., Prusiner, S. B., and Cohen, F. E. (1996) Fold. Des. 1, 13-19
10. Jackson, G. S., Hosszu, L. L., Power, A., Hill, A. F., Kenney, J., Saibil, H., Craven, C. J., Waltho, J. P., Clarke, A. R., and Collinge, J. (1999) Science 283, 1935-1937
11. Supattapone, S., Bosque, P., Muramoto, T., Wille, H., Aargard, C., Peretz, D., Nguyen, H., Heinrich, C., Torchia, M., Safar, J., Cohen, F. E., DeArmond, S. J., Prusiner, S. B., and Scott, M. (1999) Cell 96, 869-878
12. Kaneko, K., Ball, H. L., Wille, H., Zhang, H., Groth, D., Torchia, M., Tremblay, P., Safar, J., Prusiner, S. B., DeArmond, S. J., Prusiner, S. B., DeArmond, S. J., Baldwin, M. A., and Cohen, F. E. (2000) J. Mol. Biol. 295, 997-1007
13. Forloni, G., Angeretti, N., Chiesa, R., Monzani, E., Salmona, M., Bugiani, O., and Tagliavini, F. (1993) Nature 362, 543-546
14. Büeler, H., Fisher, M., Lang, Y., Bluethmann, H., Lipp, H. P., DeArmond, S. J., Prusiner, S. B., Auet, M., and Weissmann, C. (1992) Nature 356, 577-582
15. Lindquist, S. (1997) Cell 89, 495-498
16. Wickner, R. B., Edskes, H. K., Makkelein, M. L., Taylor, K. L., and Moriyama, H. (1999) J. Biol. Chem. 274, 555-558
17. Serio, T. R., Cashikar, A. G., Kowal, A. S., Sawicki, G. J., Moslehi, J. J., Serpell, L., Arnsdorf, M. F., and Lindquist, S. L. (2000) Science 289, 1317-1321
18. Chien, P., and Weissman, J. S. (2001) Nature 410, 223-227
19. Jarrett, J. T., and Lansbury, P. T., Jr. (1993) Cell 73, 1055-1058
20. Come, J., Fraser, P. E., and Lansbury, P. T., Jr. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 5959-5963
21. Riek, R., Hornemann, S., Wider, G., Billeter, M., Glockshuber, R., and Wütrich, K. (1996) Nature 382, 180-182
22. Donne, D. G., Viles, J. H., Groth, D., Mehlhorn, I., James, T. L., Cohen, F. E., Prusiner, S. B., Wright, P. E., and Dyson, H. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 13452-13457
23. Zahn, R., Liu, A., Luhrs, T., Riek, R., von Schroetter, C., Lopez Garcia, F., Billeter, M., Calzolai, L., Wider, G., and Wuthrich, K. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 145-150
24. Viles, J. H., Donne, D., Kroon, G., Prusiner, S. B., Cohen, F. E., Dyson, H. J., and Wright, P. E. (2001) Biochemistry 40, 2743-2753
25. Kelly, J. W. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 930-932
26. Telling, G. C., Scott, M., Mastrianni, J., Gabizon, R., Torchia, M., Cohen, F. E., DeArmond, S. J., and Prusiner, S. B. (1995) Cell 83, 79-90
27. Caughey, B., Brown, K., Raymond, G. J., Katzenstein, G. E., and Thresher, W. (1994) J. Virol. 68, 2135-2141
28. Nandi, P. K., and Leclerc, E. (1999) Arch. Virol. 144, 1751-1763
29. Gabus, C., Derrington, E., Leblanc, P., Chnaiderman, J., Dormont, D., Swietnicki, W., Morillas, M., Surewicz, W. K., Marc, D., Nandi, P., and Darlix, J. L. (2001) J. Biol. Chem. 276, 19301-19309
30. Zahn, R., von Schroetter, C., and Wuthrich, K. (1997) FEBS Lett. 417, 400-404
31. Mohana-Borges, R., Pacheco, A. B. F., Sousa, F. J. R., Foguel, D., Almeida, D. F., and Silva, J. L. (2000) J. Biol. Chem. 275, 4708-4712
32. Lima, L. M. T., Foguel, D., and Silva, J. L. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 14289-14294
33. Zhang, H., Kaneko, K., Nguyen, J. T., Livshits, T., Baldwin, M., Cohen, F. E. James, T. L., and Prusiner, S. B. (1995) J. Mol. Biol. 250, 514-526
34. Canete, M., Villanueva, A., Juarranz, A., and Stockert, J. C. (1987) Cell. Mol. Biol. 33, 191-199
35. Nandi, P. K. (1997) Arch. Virol. 142, 2537-2545
36. Nandi, P. K. (1998) Arch. Virol. 143, 1251-1263
37. Pabo, C. O., and Sauer, R. T. (1992) Annu. Rev. Biochem. 61, 1053-1095
38. Venyaminov, S. Yu., and Yang, J. T. (1996) in Circular Dichroism and the Conformation Analysis of Biomolecules, (Fasman, G. D., ed) pp. 69-107, Plenum Publishing Corp., New York
39. Wang, J. M., Takeda, A., Yang, J. T., and Wu, C. S. (1992) J. Protein Chem. 11, 157-164
40. Venyaminov, S. Y., and Vassilenko, K. S. (1994) Anal. Biochem. 222, 176-184
41. Hegde, R. S., Mastrianni, J. A., Scott, M. R., DeFea, K. A., Tremblay, P., Torchia, M., DeArmond, S. J., Prusiner, S. B., and Lingappa, V. R. (1998) Science 279, 827-834
42. Brown, M. S., and Golsdstein, J. L. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 11041-11042
43. Gabus, C., Auxilien, S., Pechoux, C., Dormont, D., Swietnicki, W., Morillas, M., Surewicz, W., Nandi, P., and Darlix, J. L. (2001) J. Mol. Biol. 307, 1011-1021
44. Phillips, S. E. (1994) Annu. Rev. Biophys. Biomol. Struct. 23, 671-701
45. Raumann, B. E., Rould, M. A., Pabo, C. O., and Sauer, R. T. (1994) Nature 367, 754-757
46. Foguel, D., and Silva, J. L. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8244-8247
47. Burley, S. K. (1996) Curr. Opin. Struct. Biol. 6, 69-75
48. Antson, A. A. (2000) Curr. Opin. Struct. Biol. 10, 87-94
49. Kellings, K., Meyer, N., Mirenda, C., Prusiner, S. B., and Riesner, D. (1992) J. Gen. Virol. 73, 1025-1029
50. Weissman, C. (1991) Nature 252, 679-683
51. Cohen, F. E. (1999) J. Mol. Biol. 293, 313-320
52. Baskakov, I. V., Legname, G., Prusiner, S. B., and Cohen, F. E. (2001) J. Biol. Chem. 276, 19687-19690
53. Callahan, M. A., Xiong, L. W., and Caughey, B. (2001) J. Biol. Chem. 276, 28022-28028
54. Lee, C., Park, S. H., Lee, M. Y., and Yu, M. H. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 7727-7731
55. Carr, C. M., Chaudhry, C., and Kim, P. S. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 14306-14313
56. Gaspar, L. P., Terezan, A. F., Pinheiro, A. S., Foguel, D., Rebello, M. A., and Silva, J. L. (2001) J. Biol. Chem. 276, 7415-7421
57. Ferrão-Gonzales, A. D., Souto, S. O., Silva, J. L., and Foguel, D. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 6445-6450
58. Supattapone, S., Nguyen, H. O., Cohen, F. E., Prusiner, S. B., and Scott, M. R. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 14529-14534
59. Harper, J. D., and Lansbury, P. T., Jr. (1997) Annu. Rev. Biochem. 66, 385-407
60. Goldberg, M. S., and Lansbury, P. T., Jr. (2000) Nat. Cell Biol. 2, 115-119