An activating mutation in sos-1 identifies its Dbl domain as a critical inhibitor of the epidermal growth factor receptor pathway during Caenorhabditis elegans vulval development

Molecular and Cellular Biology

Volumn 27, Issue 10, 2007, Pages 3695-3707

  Modzelewska, Katarzyna ^a   Elgort, Marc G ^a   Huang, Jingyu ^a   Jongeward, Gregg ^b,c   Lauritzen, Amara ^a   Yoon, Charles H ^b,d   Sternberg, Paul W ^b   Moghal, Nadeem ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF THE PACIFIC   (United States)

^d New York Presbyterian Hospital Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENZYME ACTIVATION; GENE; GENE MUTATION; MISSENSE MUTATION; MOLECULAR MODEL; NONHUMAN; PARASITE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; SOS 1 GENE; VULVA;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; PROTEIN STRUCTURE, TERTIARY; RAF KINASES; RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA INTERFERENCE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SOS1 PROTEIN;

CAENORHABDITIS ELEGANS;

EID: 34248140184     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01630-06     Document Type: Article

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