P21Ras activation by the guanine nucleotide exchange factor Sos, requires the Sos/Grb2 interaction and a second ligand-dependent signal involving the Sos N-terminus

Oncogene

Volumn 13, Issue 10, 1996, Pages 2055-2065

  Byrne, Jennifer L ^a   Paterson, Hugh F ^a   Marshall, Christopher J ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Grb2; hSos; p21Ras; Signal transduction

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; MUTANT PROTEIN; PROTEIN; PROTEIN P21; RAS PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

3T3 CELLS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIFFERENTIATION; CELL DIVISION; COS CELLS; DNA; GRB2 ADAPTOR PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; PHEOCHROMOCYTOMA; PROTEINS; PROTO-ONCOGENE PROTEINS P21(RAS); RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TUMOR CELLS, CULTURED;

ANIMALIA; MAMMALIA;

EID: 0029849810     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Aronheim A, Engelberg D, Li N, AlAlawi N, Schlessinger J and Karin M. (1994). Cell, 78, 949-961.
2. Bar-Sagi D and Feramisco JR. (1985). Cell, 42, 841-848.
3. Bowtell D, Fu P, Simon M and Senior P. (1992). Proc. Natl. Acad. Sci. USA, 89, 6511-6515.
4. Buday L and Downward J. (1993). Cell, 73, 611-620.
5. Buday L, Egan SE, Viciana PR, Cantrell DA and Downward J. (1994) J. Biol. Chem., 269, 9019-9023.
6. Cen H, Papageorge AG, Vass WC, Zhang K and Lowy DR. (1993). Mol. Cell. Biol. 13, 7718-7724.
7. Chardin P, Camonis JH, Gale NW, Van Aelst L, Schlessinger J, Wigler MH and Bar-Sagi D. (1993). Science, 260, 1338-1343.
8. Clark SG, Stern MJ and Horvitz HR. (1992). Nature, 356, 340-344.
9. Cowley S, Paterson H, Kemp P and Marshall CJ. (1994). Cell 77, 841-852.
10. Dickson B and Hafen E. (1994). Curr. Opin. Gen. Devel., 4, 64-70.
11. Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM and Weinberg RA. (1993). Nature, 362, 45-51.
12. Evan GI, Lewis GK, Ramsay G and Bishop JM. (1985). Mol. Cell. Biol., 5, 3610-3616.
13. Feramisco JR, Gross M, Kamata T, Rosenberg M and Sweet R. (1984). Cell, 38, 109-117.
14. Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J and BarSagi D. (1993). Nature, 362, 88-92.
15. Gomez N and Cohen P. (1991). Nature, 353, 170-173.
16. Greene LA and Tischler AS. (1976). Proc. Natl. Acad. Sci. USA, 73, 2424-2428.
17. Harlan J, Hajduk P, Yoon H and Fesik S. (1994). Nature, 371, 168-170.
18. Hashimoto Y, Matuoka K, Takenawa T, Muroya K, Hattori S and Nakamura S. (1994). Oncogene, 9, 869-875.
19. Holsinger LJ, Spencer DM, Austin DJ, Schreiber SL and Crabtree GR. (1995). Proc. Natl. Acad. Sci. USA, 92, 9810-9814.
20. Howe LR, Leevers SJ, Gómez N, Nakielny S, Cohen P and Marshall CJ. (1992). Cell, 71, 335-342.
21. Hu Q, Milfay D and Williams LT. (1995). Mol. Cell. Biol., 88, 189-198.
22. Karlovich CA, Bonfini L, McCollam L, Rogge RD, Daga A, Czeh MP and Banerjee U. (1995). Science, 268, 576-579.
23. Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B and Schlessinger J. (1993). Nature, 362, 85-88.
24. Lowenstein EJ, Daly RJ, Batzer AG, Li W, Margolis B, Lammers R, Ullrich A, Skolnik EY, Bar-Sagi D and Schlessinger J. (1992). Cell, 70, 431-442.
25. Marais R, Light Y, Paterson HF and Marshall CJ. (1995). EMBO J., 14, 3136-3145.
26. McCollam L, Bonfini L, Karlovich CA, Conway BR, Kozma LM, Banerjee U and Czech MP. (1995). J. Biol. Chem., 270, 15954-15957.
27. Miller J and Germain RM. (1986). J. Exp. Med., 164, 1478-1489.
28. Mizushima S and Nagata S. (1990). Nucl. Acids Res., 18, 5322.
29. Mulcahy LS, Smith MR and Stacey DW. (1985). Nature, 313, 241-243.
30. Pronk GJ, McGlade J, Pelicci G, Pawson T and Bos JL. (1993). J. Biol. Chem., 268.
31. Quilliam LA, Huff SY, Rabun KM, Wei W, Park W, Broek D and Der CJ. (1994). Proc. Natl. Acad. Sci. USA, 91, 8512-8516.
32. Rozakis-Adcock M, Fernley R, Wade J, Pawson T and Bowtell D. (1993) Nature, 362, 83-85.
33. Schapp D, van der Wal J, Howe LR, Marshall CJ and van Blitterswijk WJ. (1993). J. Biol. Chem., 268, 20232-20236.
34. Shou C, Farnsworth CL, Neel BG and Feig LA. (1992). Nature, 358, 351-354.
35. Stacey DW and Kung H.-F. (1984). Nature, 310, 508-511.
36. Tanaka S, Morishita T, Hashimoto Y, Hattori S, Nakamura S, Shibuya M, Matuoka K, Takenawa T, Kurata T, Nagashima K and Matsuda M. (1994). Proc. Natl. Acad. Sci. USA, 91, 3443-3447.
37. Traverse S, Gomez N, Paterson H, Marshall CJ and Cohen P. (1992). Biochem J., 288, 351-355.
38. Van Biesen T, Hawes BE, Luttrell DK, Krueger KM, Touhara K, Porfiri E, Sakaue M, Luttrell LM and Lefkowitz R. (1995). Nature. 376, 781-784.
39. Wang W, Fisher EMC, Jia Q, Dunn J, Porfiri E, Downward J and Egan SE. (1995). Nat. Genet., 10, 294-300.