-
1
-
-
0038771965
-
The "Shp"ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
-
Neel BG, Gu H, Pao L. The "Shp"ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem Sci 2003;28:284-93.
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 284-293
-
-
Neel, B.G.1
Gu, H.2
Pao, L.3
-
4
-
-
0038278866
-
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myetodysplastic syndromes and acute myeloid leukemia
-
Tartaglia M, Niemeyer CM, Fragale A, et al. Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myetodysplastic syndromes and acute myeloid leukemia. Nat Genet 2003;34:148-50.
-
(2003)
Nat Genet
, vol.34
, pp. 148-150
-
-
Tartaglia, M.1
Niemeyer, C.M.2
Fragale, A.3
-
5
-
-
12144286410
-
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis
-
Loh ML, Vattikuti S, Schubbert S, et al. Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis. Blood 2004;103:2325-31.
-
(2004)
Blood
, vol.103
, pp. 2325-2331
-
-
Loh, M.L.1
Vattikuti, S.2
Schubbert, S.3
-
6
-
-
3142620903
-
Genetic evidence for lineage- and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia
-
Tartaglia M, Martinelli S, Cazzaniga G, et al. Genetic evidence for lineage- and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia. Blood 2004;104:307-13.
-
(2004)
Blood
, vol.104
, pp. 307-313
-
-
Tartaglia, M.1
Martinelli, S.2
Cazzaniga, G.3
-
7
-
-
0032521428
-
Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2
-
Barford D, Neel BG. Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2. Structure 1998;6:249-54.
-
(1998)
Structure
, vol.6
, pp. 249-254
-
-
Barford, D.1
Neel, B.G.2
-
8
-
-
18344385476
-
Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
-
Tartaglia M, Mehler EL, Goldberg R, et al. Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nat Genet 200l;29:465-8.
-
(2001)
Nat Genet
, vol.29
, pp. 465-468
-
-
Tartaglia, M.1
Mehler, E.L.2
Goldberg, R.3
-
9
-
-
0023898932
-
The ras gene family and human carcinogenesis
-
Bos JL. The ras gene family and human carcinogenesis. Mutat Res 1988;195:255-71.
-
(1988)
Mutat Res
, vol.195
, pp. 255-271
-
-
Bos, J.L.1
-
10
-
-
0035923521
-
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
-
Bhattacharjee A, Richards WG, Staunton J, et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci USA 2001;98:13790-5.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13790-13795
-
-
Bhattacharjee, A.1
Richards, W.G.2
Staunton, J.3
-
11
-
-
0038670241
-
Mutational analysis of the tyrosine kinome in colorectal cancers
-
Bardelli A, Parsons DW, Silliman N, et al. Mutational analysis of the tyrosine kinome in colorectal cancers. Science (Wash DC) 2003;300:949.
-
(2003)
Science (Wash DC)
, vol.300
, pp. 949
-
-
Bardelli, A.1
Parsons, D.W.2
Silliman, N.3
-
12
-
-
0036895599
-
Missense mutations of the BRAF gene in human lung adenocarcinoma
-
Naoki K, Chen TH, Richards WG, Sugarbaker DJ, Meyerson M. Missense mutations of the BRAF gene in human lung adenocarcinoma. Cancer Res 2002;62:7001-3.
-
(2002)
Cancer Res
, vol.62
, pp. 7001-7003
-
-
Naoki, K.1
Chen, T.H.2
Richards, W.G.3
Sugarbaker, D.J.4
Meyerson, M.5
-
13
-
-
4043056497
-
Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation
-
Araki T, Mohi MG, Ismat FA, et al. Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation. Nat Med 2004;10:849-57.
-
(2004)
Nat Med
, vol.10
, pp. 849-857
-
-
Araki, T.1
Mohi, M.G.2
Ismat, F.A.3
-
14
-
-
0037300995
-
Spectrum of mutations in PTPN11 and genotype-phenotype correlation in 96 patients with Noonan syndrome and five patients with cardio-facio-cutaneous syndrome
-
Musante L, Kehl HG, Majewski F, et al. Spectrum of mutations in PTPN11 and genotype-phenotype correlation in 96 patients with Noonan syndrome and five patients with cardio-facio-cutaneous syndrome. Eur J Hum Genet 2003;11:201-6.
-
(2003)
Eur J Hum Genet
, vol.11
, pp. 201-206
-
-
Musante, L.1
Kehl, H.G.2
Majewski, F.3
-
15
-
-
0033034390
-
Molecular biology of neuroblastoma
-
Maris JM, Matthay KK. Molecular biology of neuroblastoma. J Clin Oncol 1999;17:2264-79.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2264-2279
-
-
Maris, J.M.1
Matthay, K.K.2
-
16
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-39.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
17
-
-
2342624080
-
EGFR mutations in lung cancer; correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer; correlation with clinical response to gefitinib therapy. Science (Wash DC) 2004;304:1497-500.
-
(2004)
Science (Wash DC)
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
18
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature (Lond) 2002;417:949-54.
-
(2002)
Nature (Lond)
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
19
-
-
0036894746
-
BRAF and RAS mutations in human lung cancer and melanoma
-
Brose MS, Volpe P, Feldman M, et al. BRAF and RAS mutations in human lung cancer and melanoma. Cancer Res 2002;62:6997-7000.
-
(2002)
Cancer Res
, vol.62
, pp. 6997-7000
-
-
Brose, M.S.1
Volpe, P.2
Feldman, M.3
-
20
-
-
0037194728
-
Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status
-
Rajagopalan H, Bardelli A, Lengauer C, et al. Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Nature (Lond) 2002;418:934.
-
(2002)
Nature (Lond)
, vol.418
, pp. 934
-
-
Rajagopalan, H.1
Bardelli, A.2
Lengauer, C.3
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