Microtubule-stabilizing agent prevents protein accumulation-induced loss of synaptic markers

European Journal of Pharmacology

Volumn 562, Issue 1-2, 2007, Pages 20-27

  Butler, David ^a   Bendiske, Jennifer ^b   Michaelis, Mary L ^c   Karanian, David A ^a   Bahr, Ben A ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c UNIVERSITY OF KANSAS   (United States)

Author keywords

Alzheimer's disease; Microtubule integrity; Protein deposition; Synaptic decline; Taxol derivative; TX67

Indexed keywords

10 SUCCINYL PACLITAXEL; ALPHA TUBULIN; CHLOROQUINE; GLUTAMATE RECEPTOR; PACLITAXEL DERIVATIVE; SYNAPTOPHYSIN; TX 67; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; IMMUNOREACTIVITY; MICROTUBULE; NEWBORN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SYNAPSE;

ACETYLATION; ACTINS; ANIMALS; CHLOROQUINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; IMMUNOBLOTTING; ORGAN CULTURE TECHNIQUES; PACLITAXEL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUTAMATE; SYNAPTOPHYSIN; TIME FACTORS; TUBULIN MODULATORS;

EID: 33947519211     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.01.053     Document Type: Article

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