Amyloid β protein is internalized selectively by hippocampal field CA1 and causes neurons to accumulate amyloidogenic carboxyterminal fragments of the amyloid precursor protein

Journal of Comparative Neurology

Volumn 397, Issue 1, 1998, Pages 139-147

  Bahr, Ben A ^a,b,d   Hoffman, Keith B ^b   Yang, Austin J ^b   Hess, Ursula S ^c   Glabe, Charles G ^b   Lynch, Gary ^b  

^a Cortex Pharmaceuticals Inc ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Alzheimer's disease; Long term hippocampal slices; Peptide internalization; Selective pathogenesis; Synaptophysin

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; SYNAPTOPHYSIN;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CARBOXY TERMINAL SEQUENCE; CELL DEGENERATION; HIPPOCAMPUS; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PYRAMIDAL NERVE CELL; RAT; SYNAPTIC MEMBRANE; SYNAPTIC TRANSMISSION;

AMYLOID BETA-PROTEIN; ANIMALS; CARBOXYLIC ACIDS; HIPPOCAMPUS; NERVE TISSUE PROTEINS; NEURONS; PEPTIDE FRAGMENTS; RATS; STOCHASTIC PROCESSES; SYNAPTOPHYSIN;

EID: 0032551528     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19980720)397:1<139::AID-CNE10>3.0.CO;2-K     Document Type: Article

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