메뉴 건너뛰기




Volumn 55, Issue 9, 1996, Pages 964-972

Reduction of Acetylated α-Tubulin Immunoreactivity in Neurofibrillary Tangle-bearing Neurons in Alzheimer's Disease

Author keywords

Acetylated tubulin; Alzheimer's disease; Microtubule stability; Neurofibrillary tangles; Tau

Indexed keywords

TAU PROTEIN; TUBULIN;

EID: 0030240325     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199609000-00003     Document Type: Article
Times cited : (164)

References (61)
  • 1
    • 0025331720 scopus 로고
    • Rating of lesions in senile dementia of the Alzheimertype: Concordance between laboratories. An European multicenter study under the auspices of Eurage
    • Duyckaerts C, Delaère P, Hauw JJ, et al. Rating of lesions in senile dementia of the Alzheimertype: Concordance between laboratories. An European multicenter study under the auspices of Eurage. J Neurol Sci 1990;97:295-323
    • (1990) J Neurol Sci , vol.97 , pp. 295-323
    • Duyckaerts, C.1    Delaère, P.2    Hauw, J.J.3
  • 2
    • 0026740795 scopus 로고
    • Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
    • Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 1992;42:631-39
    • (1992) Neurology , vol.42 , pp. 631-639
    • Arriagada, P.V.1    Growdon, J.H.2    Hedley-Whyte, E.T.3    Hyman, B.T.4
  • 3
    • 0026446679 scopus 로고
    • The pathology of the neuronal cytoskeleton in Alzheimer's disease
    • Brion JP. The pathology of the neuronal cytoskeleton in Alzheimer's disease. Biochem Biophy Acta 1992;1160:134-42
    • (1992) Biochem Biophy Acta , vol.1160 , pp. 134-142
    • Brion, J.P.1
  • 5
    • 0028918383 scopus 로고
    • Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease
    • Cras P, Smith MA, Richey PL, Siedlak SL, Mulvihill P, Perry G. Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease. Acta Neuropathol (Berl) 1995;89:291-95
    • (1995) Acta Neuropathol (Berl) , vol.89 , pp. 291-295
    • Cras, P.1    Smith, M.A.2    Richey, P.L.3    Siedlak, S.L.4    Mulvihill, P.5    Perry, G.6
  • 6
    • 37049048544 scopus 로고
    • Paired helical filaments in electron microscopy of Alzheimer's disease
    • Kidd M. Paired helical filaments in electron microscopy of Alzheimer's disease. Nature 1963;197:192-93
    • (1963) Nature , vol.197 , pp. 192-193
    • Kidd, M.1
  • 7
    • 78651158156 scopus 로고
    • Ultrastructural studies in Alzheimer's presenile dementia
    • Terry RD, Gonatas NK, Weiss M. Ultrastructural studies in Alzheimer's presenile dementia. Am J Pathol 1964;44:669-97
    • (1964) Am J Pathol , vol.44 , pp. 669-697
    • Terry, R.D.1    Gonatas, N.K.2    Weiss, M.3
  • 8
    • 0022257253 scopus 로고
    • Mise en évidence immunologique de la protéine tau au niveau des lésions de dégénérescence neurofibrillaire de la maladie d'Alzheimer
    • Brion JP, Passareiro H, Nunez J, Flament-Durand J. Mise en évidence immunologique de la protéine tau au niveau des lésions de dégénérescence neurofibrillaire de la maladie d'Alzheimer. Arch Biol (Brux) 1985;95:229-35
    • (1985) Arch Biol (Brux) , vol.95 , pp. 229-235
    • Brion, J.P.1    Passareiro, H.2    Nunez, J.3    Flament-Durand, J.4
  • 9
    • 0022980104 scopus 로고
    • Alzheimer's disease: Tau proteins, the promoting factors of microtubule assembly, are major components of paired helical filaments
    • Delacourte A, Defossez A. Alzheimer's disease: Tau proteins, the promoting factors of microtubule assembly, are major components of paired helical filaments. J Neurol Sci 1986;76:173-86
    • (1986) J Neurol Sci , vol.76 , pp. 173-186
    • Delacourte, A.1    Defossez, A.2
  • 11
    • 0022723508 scopus 로고
    • One of the antigenic determinants of paired helical filaments is related to tau protein
    • Nukina N, Ihara Y. One of the antigenic determinants of paired helical filaments is related to tau protein. J Biochem 1986;99:1541-44
    • (1986) J Biochem , vol.99 , pp. 1541-1544
    • Nukina, N.1    Ihara, Y.2
  • 12
    • 0002792366 scopus 로고
    • Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau
    • Goedert M, Wischik CM, Crowther RA, Walker JE, Klug A. Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau. Proc Natl Acad Sci USA 1988;85:4051-55
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4051-4055
    • Goedert, M.1    Wischik, C.M.2    Crowther, R.A.3    Walker, J.E.4    Klug, A.5
  • 13
    • 0025904444 scopus 로고
    • A68 proteins are major subunits of Alzheimer disease paired helical filaments and derivatized forms of normal tau
    • Lee VMY, Balm BJ, Otvos L, Trojanowski JQ. A68 proteins are major subunits of Alzheimer disease paired helical filaments and derivatized forms of normal tau. Science 1991;251:675-78
    • (1991) Science , vol.251 , pp. 675-678
    • Lee, V.M.Y.1    Balm, B.J.2    Otvos, L.3    Trojanowski, J.Q.4
  • 14
    • 0009364134 scopus 로고
    • The microtubule-associated protein, tau, is a major antigenic component of paired helical filaments in Alzheimer's disease
    • Kosik KS, Joachim CL, Selkoe DJ. The microtubule-associated protein, tau, is a major antigenic component of paired helical filaments in Alzheimer's disease. Proc Natl Acad Sci USA 1986;83:4044-48
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4044-4048
    • Kosik, K.S.1    Joachim, C.L.2    Selkoe, D.J.3
  • 15
    • 0003986552 scopus 로고
    • Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease
    • Wischik CM, Novak M, Thogersen HC, et al. Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease. Proc Natl Acad Sci USA 1988;85:4506-10
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4506-4510
    • Wischik, C.M.1    Novak, M.2    Thogersen, H.C.3
  • 16
    • 1842685948 scopus 로고
    • Neurofibrillary tangles of Alzheimer disease share anligenic determinants with the axonal microtubule-associated protein tau
    • Wood JG, Mirra SS, Pollock NJ, Binder LI. Neurofibrillary tangles of Alzheimer disease share anligenic determinants with the axonal microtubule-associated protein tau. Proc Natl Acad Sci USA 1986;83:4040-43
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4040-4043
    • Wood, J.G.1    Mirra, S.S.2    Pollock, N.J.3    Binder, L.I.4
  • 17
    • 0017649032 scopus 로고
    • Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin
    • Cleveland DW, Hwo SY, Kirschner MW. Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin. J Molec Biol 1977;116:207-25
    • (1977) J Molec Biol , vol.116 , pp. 207-225
    • Cleveland, D.W.1    Hwo, S.Y.2    Kirschner, M.W.3
  • 18
    • 0022724941 scopus 로고
    • Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease
    • Ihara Y, Nukina N, Miura R, Ogawara M. Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease. J Biochem 1986;99:1807-10
    • (1986) J Biochem , vol.99 , pp. 1807-1810
    • Ihara, Y.1    Nukina, N.2    Miura, R.3    Ogawara, M.4
  • 19
    • 0025949088 scopus 로고
    • A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities
    • Brion JP, Hanger DP, Couck AM, Anderton BH. A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities. Biochem J 1991;279:831-36
    • (1991) Biochem J , vol.279 , pp. 831-836
    • Brion, J.P.1    Hanger, D.P.2    Couck, A.M.3    Anderton, B.H.4
  • 20
    • 0025311008 scopus 로고
    • Phosphorylation of tau proteins: A major event during the process of neurofibrillary degeneration. A comparative study between Alzheimer's disease and Down's syndrome
    • Flament S, Delacourte A, Mann DMA. Phosphorylation of tau proteins: A major event during the process of neurofibrillary degeneration. A comparative study between Alzheimer's disease and Down's syndrome. Brain Res 1990;516:15-19
    • (1990) Brain Res , vol.516 , pp. 15-19
    • Flament, S.1    Delacourte, A.2    Mann, D.M.A.3
  • 22
    • 0026451030 scopus 로고
    • Immunocytochemistry of neurofibrillary tangles with antibodies to subrogions of tau protein: Identification of hidden and cleaved tau epitopes and a new phosphorylation site
    • Dickson DW, Ksiezak-Reding H, Liu W-K, Davies P, Crowe A, Yen S-HC. Immunocytochemistry of neurofibrillary tangles with antibodies to subrogions of tau protein: Identification of hidden and cleaved tau epitopes and a new phosphorylation site. Acta Neuropathol (Berl) 1992;84:596-605
    • (1992) Acta Neuropathol (Berl) , vol.84 , pp. 596-605
    • Dickson, D.W.1    Ksiezak-Reding, H.2    Liu, W.-K.3    Davies, P.4    Crowe, A.5    Yen, S.-H.C.6
  • 23
    • 0027945346 scopus 로고
    • Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau
    • Matsuo ES, Shin R-W, Billingsley ML, et al. Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau. Neuron 1994;13:989-1002
    • (1994) Neuron , vol.13 , pp. 989-1002
    • Matsuo, E.S.1    Shin, R.-W.2    Billingsley, M.L.3
  • 24
    • 0024151129 scopus 로고
    • Structure and utilization of tubulin isotypes
    • Sullivan KF. Structure and utilization of tubulin isotypes. Annu Rev Cell Biol 1988;4:687-716
    • (1988) Annu Rev Cell Biol , vol.4 , pp. 687-716
    • Sullivan, K.F.1
  • 25
    • 0024094998 scopus 로고
    • Tau proteins: The molecular structure and mode of binding to microtubules
    • Hirokawa N, Shiomura Y, Okabe S. Tau proteins: The molecular structure and mode of binding to microtubules. J Cell Biol 1988;107:1449-59
    • (1988) J Cell Biol , vol.107 , pp. 1449-1459
    • Hirokawa, N.1    Shiomura, Y.2    Okabe, S.3
  • 26
    • 0022896901 scopus 로고
    • Tau protein function in living cells
    • Drubin DG, Kirschner MW. Tau protein function in living cells. J Cell Biol 1986;103:2739-46
    • (1986) J Cell Biol , vol.103 , pp. 2739-2746
    • Drubin, D.G.1    Kirschner, M.W.2
  • 27
    • 0024438227 scopus 로고
    • Expression of multiple tau isoforms and microtubule bundle formation in flbroblasts transfected with a single tau cDNA
    • Kanai Y, Takemura R, Oshima T, et al. Expression of multiple tau isoforms and microtubule bundle formation in flbroblasts transfected with a single tau cDNA. J Cell Biol 1989;109:1173-84
    • (1989) J Cell Biol , vol.109 , pp. 1173-1184
    • Kanai, Y.1    Takemura, R.2    Oshima, T.3
  • 28
    • 0021338217 scopus 로고
    • Phosphorylation affects the ability of tau protein to promote microtubule assembly
    • Lindwall G, Cole RD. Phosphorylation affects the ability of tau protein to promote microtubule assembly. J Biol Chem 1984;259:5301-6
    • (1984) J Biol Chem , vol.259 , pp. 5301-5306
    • Lindwall, G.1    Cole, R.D.2
  • 29
    • 0018649358 scopus 로고
    • Spongiform alterations in brain biopsies of presenile dementia
    • Flament-Durand J, Couck AM. Spongiform alterations in brain biopsies of presenile dementia. Acta Neuropathol (Berl) 1979;46:159-62
    • (1979) Acta Neuropathol (Berl) , vol.46 , pp. 159-162
    • Flament-Durand, J.1    Couck, A.M.2
  • 31
    • 0005026184 scopus 로고
    • Disturbances of axoplasmic transport in Alzheimer's disease
    • Weiss DG, Gorio A, Eds. Berlin: Springer
    • Dustin P, Flament-Durand J. Disturbances of axoplasmic transport in Alzheimer's disease. In: Weiss DG, Gorio A, Eds. Axoplasmic transport in physiology and pathology. Berlin: Springer, 1982:131-36
    • (1982) Axoplasmic Transport in Physiology and Pathology , pp. 131-136
    • Dustin, P.1    Flament-Durand, J.2
  • 32
    • 0024368871 scopus 로고
    • Accumulation of smooth endoplasmic reticulum in Alzheimer's disease: New morphological evidence of axoplasmic flow disturbances
    • Richard S, Brion JP, Couck AM, Flament-Durand J. Accumulation of smooth endoplasmic reticulum in Alzheimer's disease: New morphological evidence of axoplasmic flow disturbances. J Submicrosc Cytol 1989;21:461-67
    • (1989) J Submicrosc Cytol , vol.21 , pp. 461-467
    • Richard, S.1    Brion, J.P.2    Couck, A.M.3    Flament-Durand, J.4
  • 33
    • 0024342580 scopus 로고
    • Hypothesis: Microtubules, a key to Alzheimer disease
    • Matsuyama SS, Jarvik LF. Hypothesis: Microtubules, a key to Alzheimer disease. Proc Natl Acad Sci USA 1989;86:8152-56
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 8152-8156
    • Matsuyama, S.S.1    Jarvik, L.F.2
  • 34
    • 0021812742 scopus 로고
    • Reductions in soluble brain proteins in older subjects with Down's syndrome
    • Borthwick NM, Gordon A, Yates CM. Reductions in soluble brain proteins in older subjects with Down's syndrome. J Neurol Sci 1985;68:205-14
    • (1985) J Neurol Sci , vol.68 , pp. 205-214
    • Borthwick, N.M.1    Gordon, A.2    Yates, C.M.3
  • 35
    • 0021885863 scopus 로고
    • Reduced proteins in temporal cortex in Alzheimer's disease: An electrophoretic study
    • Borthwick NM, Yates CM, Gordon A. Reduced proteins in temporal cortex in Alzheimer's disease: An electrophoretic study. J Neurochem 1985;44:1436-41
    • (1985) J Neurochem , vol.44 , pp. 1436-1441
    • Borthwick, N.M.1    Yates, C.M.2    Gordon, A.3
  • 36
    • 0026578425 scopus 로고
    • Regions with abundant neurofibrillary pathology in human brain exhibit a selective reduction in levels of binding-competent τ and accumulation of abnormal τ-isoforms
    • Bramblett GT, Trojanowski JQ, Lee VM-Y. Regions with abundant neurofibrillary pathology in human brain exhibit a selective reduction in levels of binding-competent τ and accumulation of abnormal τ-isoforms (A68 proteins). Lab Invest 1992;66:212-22
    • (1992) Lab Invest , vol.66 , pp. 212-222
    • Bramblett, G.T.1    Trojanowski, J.Q.2    Lee, V.M.-Y.3
  • 37
    • 0022550260 scopus 로고
    • Defective brain microtubule assembly in Alzheimer's disease
    • Iqbal K, Grundke-Iqbal I, Zaidi T, et al. Defective brain microtubule assembly in Alzheimer's disease. Lancet 1986;i:421-26
    • (1986) Lancet , vol.1 , pp. 421-426
    • Iqbal, K.1    Grundke-Iqbal, I.2    Zaidi, T.3
  • 38
    • 0027237861 scopus 로고
    • τ in Paired helical filaments is functionally distinct from fetal T: Assembly incompetence of paired helical filament-T
    • Yoshida H, Ihara Y. τ in Paired helical filaments is functionally distinct from fetal T: Assembly incompetence of paired helical filament-T. J Neurochem 1993;61:1183-86
    • (1993) J Neurochem , vol.61 , pp. 1183-1186
    • Yoshida, H.1    Ihara, Y.2
  • 39
    • 0027453202 scopus 로고
    • Functional studies of Alzheimer's disease tau protein
    • Lu Q, Wood JG. Functional studies of Alzheimer's disease tau protein. J Neurosci 1993;13:508-15
    • (1993) J Neurosci , vol.13 , pp. 508-515
    • Lu, Q.1    Wood, J.G.2
  • 40
    • 0028269666 scopus 로고
    • Microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype
    • Strittmatter WJ, Weisgraber KH, Goedert M, et al. Microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype. Exp Neurol 1994;125:163-71
    • (1994) Exp Neurol , vol.125 , pp. 163-171
    • Strittmatter, W.J.1    Weisgraber, K.H.2    Goedert, M.3
  • 41
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer-related changes
    • Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol (Berl) 1991;82:239-59
    • (1991) Acta Neuropathol (Berl) , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 42
    • 0026097837 scopus 로고
    • Tau in Alzheimer neurofibrillary tangles: N- And C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal phosphorylation site
    • Brion JP, Hanger DP, Bruce MT, Couck AM, Flament-Durand J, Anderten BH. Tau in Alzheimer neurofibrillary tangles: N- and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal phosphorylation site. Biochem J 1991;273:127-33
    • (1991) Biochem J , vol.273 , pp. 127-133
    • Brion, J.P.1    Hanger, D.P.2    Bruce, M.T.3    Couck, A.M.4    Flament-Durand, J.5    Anderten, B.H.6
  • 43
    • 0024529404 scopus 로고
    • Distribution of tau proteins in the normal human central and peripheral nervous system
    • Trojanowski JQ, Schuck T, Schmidt ML, Lee VMY. Distribution of tau proteins in the normal human central and peripheral nervous system. J Histochem Cytochem 1989;37:209-15
    • (1989) J Histochem Cytochem , vol.37 , pp. 209-215
    • Trojanowski, J.Q.1    Schuck, T.2    Schmidt, M.L.3    Lee, V.M.Y.4
  • 44
    • 0023187071 scopus 로고
    • Posttranslational modifications of α-tubulin: Acetylated and detyrosinated forms in axons of rat cerebellum
    • Cambray-Deakin MA, Burgoyne RD. Posttranslational modifications of α-tubulin: Acetylated and detyrosinated forms in axons of rat cerebellum. J Cell Biol 1987;104:1569-74
    • (1987) J Cell Biol , vol.104 , pp. 1569-1574
    • Cambray-Deakin, M.A.1    Burgoyne, R.D.2
  • 45
    • 0024417670 scopus 로고
    • The expression of acetylated microtubules during axonal and dendritic growth in cerebellar macroneurons which develop in vitro
    • Ferreira A, Caceres A. The expression of acetylated microtubules during axonal and dendritic growth in cerebellar macroneurons which develop in vitro. Dev Brain Res 1989;49:205-13
    • (1989) Dev Brain Res , vol.49 , pp. 205-213
    • Ferreira, A.1    Caceres, A.2
  • 46
    • 0028946926 scopus 로고
    • Three-dimensional organization of stable microtubules and the Golgi apparatus in the somata of developing chick sensory neurons
    • Letourneau PC, Wire JP. Three-dimensional organization of stable microtubules and the Golgi apparatus in the somata of developing chick sensory neurons. J Neurocytol 1995;24:207-23
    • (1995) J Neurocytol , vol.24 , pp. 207-223
    • Letourneau, P.C.1    Wire, J.P.2
  • 47
    • 0020540736 scopus 로고
    • Chlamydamonas alpha-tubulin post-translationally modified by acetylation on the epsilon-amino group of a lysine
    • L'Hernault SW, Rosenbaum JL. Chlamydamonas alpha-tubulin post-translationally modified by acetylation on the epsilon-amino group of a lysine. J Cell Biol 1985;97:258-69
    • (1985) J Cell Biol , vol.97 , pp. 258-269
    • L'Hernault, S.W.1    Rosenbaum, J.L.2
  • 48
    • 0022452231 scopus 로고
    • The acetylation of alpha-tubulin and its relationship to the assembly and disassembly of microtubules
    • Maruta H, Greer K, Rosenbaum JL. The acetylation of alpha-tubulin and its relationship to the assembly and disassembly of microtubules. J Cell Biol 1986;103:571-79
    • (1986) J Cell Biol , vol.103 , pp. 571-579
    • Maruta, H.1    Greer, K.2    Rosenbaum, J.L.3
  • 49
    • 0023513805 scopus 로고
    • A quantitative study of frontal cortex dendritic microtubules in patients with Alzheimer's disease
    • Paula-Barbosa M, Tavares MA, Cadete-Leite A. A quantitative study of frontal cortex dendritic microtubules in patients with Alzheimer's disease. Brain Res 1987;416:139-42
    • (1987) Brain Res , vol.416 , pp. 139-142
    • Paula-Barbosa, M.1    Tavares, M.A.2    Cadete-Leite, A.3
  • 51
    • 0028984525 scopus 로고
    • Distribution and expression of the α-tubulin mRNA in the hippocampus and temporal cortex in Alzheimer's disease
    • Brion JP, Flament-Durand J. Distribution and expression of the α-tubulin mRNA in the hippocampus and temporal cortex in Alzheimer's disease. Path Res Pract 1995;191:490-98
    • (1995) Path Res Pract , vol.191 , pp. 490-498
    • Brion, J.P.1    Flament-Durand, J.2
  • 52
    • 0024593690 scopus 로고
    • Dynamics of α-tubulin deacetylation in intact neurons
    • Black MM, Baas PW, Humphries S. Dynamics of α-tubulin deacetylation in intact neurons. J Neurosci 1989;9:358-68
    • (1989) J Neurosci , vol.9 , pp. 358-368
    • Black, M.M.1    Baas, P.W.2    Humphries, S.3
  • 53
    • 0024587074 scopus 로고
    • Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease
    • Bancher C, Brunner C, Lassmann H, et al. Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease. Brain Res 1989;477:90-99
    • (1989) Brain Res , vol.477 , pp. 90-99
    • Bancher, C.1    Brunner, C.2    Lassmann, H.3
  • 56
    • 0029077257 scopus 로고
    • Decreased activity of hippocampal neurons in Alzheimer's disease is not related to the presence of neurofibrillary tangles
    • Salehi A, Ravid R, Gonatas NK, Swaab DF. Decreased activity of hippocampal neurons in Alzheimer's disease is not related to the presence of neurofibrillary tangles. J Neuropathol Exp Neurol 1995;54:704-9
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 704-709
    • Salehi, A.1    Ravid, R.2    Gonatas, N.K.3    Swaab, D.F.4
  • 57
    • 2342623319 scopus 로고
    • In vitro protein synthesis by messenger RNA from the Alzheimer's disease brain
    • Katzman R, ed., Cold Spring Harbor, New York: Cold Spring Harbor Laboratory
    • Sajdel-Sulkowska EM, Coughlin JF, Staton DM, MArotta CA. In vitro protein synthesis by messenger RNA from the Alzheimer's disease brain. In: Katzman R, ed., Biological aspects of Alzheimer's disease. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory, 1983:193-200
    • (1983) Biological Aspects of Alzheimer's Disease , pp. 193-200
    • Sajdel-Sulkowska, E.M.1    Coughlin, J.F.2    Staton, D.M.3    Marotta, C.A.4
  • 58
    • 0022516004 scopus 로고
    • Characterization of messenger RNA from the cerebral cortex of control and Alzheimer-afflicted brain
    • Guillemette JG, Wong L, Crapper McLachlan DR, Lewis PN. Characterization of messenger RNA from the cerebral cortex of control and Alzheimer-afflicted brain. J Neurochem 1986;47:987-97
    • (1986) J Neurochem , vol.47 , pp. 987-997
    • Guillemette, J.G.1    Wong, L.2    Crapper McLachlan, D.R.3    Lewis, P.N.4
  • 60
    • 0022503260 scopus 로고
    • An ultrastructural analysis of the effects of accumulation of neurofibrillary tangle in pyramidal neurons of the cerebral cortex in Alzheimer's disease
    • Sumpter PQ, Mann DMA, Davies CA, Yates PO, Snowden JS, Neary D. An ultrastructural analysis of the effects of accumulation of neurofibrillary tangle in pyramidal neurons of the cerebral cortex in Alzheimer's disease. Neuropathol Appl Neurobiol 1986;12:305-19
    • (1986) Neuropathol Appl Neurobiol , vol.12 , pp. 305-319
    • Sumpter, P.Q.1    Mann, D.M.A.2    Davies, C.A.3    Yates, P.O.4    Snowden, J.S.5    Neary, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.