Constitutive activity and inverse agonism at the α1adrenoceptors

Biochemical Pharmacology

Volumn 73, Issue 8, 2007, Pages 1076-1083

  Cotecchia, Susanna ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Adrenoceptors; Constitutive activity; G protein coupled receptors; G proteins; Inverse agonism; Molecular dynamics

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; RECEPTOR SUBTYPE;

ARTICLE; GENE MUTATION; GENE OVEREXPRESSION; HYDROGEN BOND; ISOMERIZATION; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTANT; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SITE DIRECTED MUTAGENESIS; SYSTEMATIC REVIEW; WILD TYPE;

ADRENERGIC ALPHA-ANTAGONISTS; AMINO ACID SEQUENCE; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; CRICETINAE; GTP-BINDING PROTEINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, G-PROTEIN-COUPLED;

EID: 33947158055     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.10.024     Document Type: Article

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