-
1
-
-
0030938936
-
G-protein-coupled receptors: Molecular mechanisms involved in receptor activation and selectivity of G-protein recognition
-
Wess J. G-protein-coupled receptors: molecular mechanisms involved in receptor activation and selectivity of G-protein recognition. FASEB J 1997;11:346-354.
-
(1997)
FASEB J
, vol.11
, pp. 346-354
-
-
Wess, J.1
-
2
-
-
0029923235
-
How G proteins work: A continuing story
-
Coleman DE, Sprang S. How G proteins work: a continuing story. Trends Biochem Sci 1996;21:41-44.
-
(1996)
Trends Biochem Sci
, vol.21
, pp. 41-44
-
-
Coleman, D.E.1
Sprang, S.2
-
3
-
-
0029875554
-
Heterotrimeric G proteins
-
and references therein
-
Hamm HE, Gilchrist A. Heterotrimeric G proteins. Curr Opin Cell Biol 1996;8:189-196 and references therein.
-
(1996)
Curr Opin Cell Biol
, vol.8
, pp. 189-196
-
-
Hamm, H.E.1
Gilchrist, A.2
-
5
-
-
0031565726
-
An alpha-carbon atom template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors
-
Baldwin JM, Schertler GF, Unger VM. An alpha-carbon atom template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors. J Mol Biol 1997;272:144-164.
-
(1997)
J Mol Biol
, vol.272
, pp. 144-164
-
-
Baldwin, J.M.1
Schertler, G.F.2
Unger, V.M.3
-
6
-
-
0030987069
-
How receptors talk to trimeric G proteins
-
and references therein
-
Bourne HR. How receptors talk to trimeric G proteins. Curr Opin Cell Biol 1997;9:134-42 and references therein.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 134-142
-
-
Bourne, H.R.1
-
7
-
-
0032541084
-
G protein-coupled receptors. II Mechanism of agonist activation
-
and references therein
-
Gether U, Kobilka B. G protein-coupled receptors. II Mechanism of agonist activation. J Biol Chem 1998;273:17979-17982 and references therein.
-
(1998)
J Biol Chem
, vol.273
, pp. 17979-17982
-
-
Gether, U.1
Kobilka, B.2
-
8
-
-
0031712825
-
Ab initio modeling and molecular dynamics simulation of the α1b-adrenergic receptor activation
-
and references therein
-
Fanelli F, Menziani C, Scheer A, Cotecchia S, De Benedetti PG. Ab initio modeling and molecular dynamics simulation of the α1b-adrenergic receptor activation. Methods Companion Methods Enzymol 1998;14:302-317 and references therein.
-
(1998)
Methods Companion Methods Enzymol
, vol.14
, pp. 302-317
-
-
Fanelli, F.1
Menziani, C.2
Scheer, A.3
Cotecchia, S.4
De Benedetti, P.G.5
-
9
-
-
0029897495
-
Constitutively active mutants of the α1B-adrenergic receptor: Role of highly conserved polar amino acids in receptor activation
-
Scheer A, Fanelli F, Costa T, De Benedetti PG, Cotecchia S. Constitutively active mutants of the α1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation. EMBO J 1996;15:3566-3578.
-
(1996)
EMBO J
, vol.15
, pp. 3566-3578
-
-
Scheer, A.1
Fanelli, F.2
Costa, T.3
De Benedetti, P.G.4
Cotecchia, S.5
-
10
-
-
0030614337
-
The activation process of the α1B-adrenergic receptor: Potential role of protonation and hydrophobicity of a highly conserved aspartate
-
Scheer A, Fanelli F, Costa T, De Benedetti PG, Cotecchia S. The activation process of the α1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate. Proc Natl Acad Sci USA 1997;94:808-813.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 808-813
-
-
Scheer, A.1
Fanelli, F.2
Costa, T.3
De Benedetti, P.G.4
Cotecchia, S.5
-
11
-
-
0027136282
-
Comparative protein modeling by satisfaction of spatial restraints
-
Sali A, Blundell TL. Comparative protein modeling by satisfaction of spatial restraints. J Mol Biol 1993;234:779-815.
-
(1993)
J Mol Biol
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
12
-
-
0029593456
-
The structure of the G protein heterotrimer Gαi1β1γ2
-
Wall MA, Coleman DE, Lee E, et al. The structure of the G protein heterotrimer Gαi1β1γ2. Cell 1995;83: 1047-1058.
-
(1995)
Cell
, vol.83
, pp. 1047-1058
-
-
Wall, M.A.1
Coleman, D.E.2
Lee, E.3
-
13
-
-
0025830469
-
A method to identify protein sequences that fold into a known three-dimensional structure
-
Bowie JU, Lüthy R, Eisenberg D. A method to identify protein sequences that fold into a known three-dimensional structure. Science 1991;253:164-170.
-
(1991)
Science
, vol.253
, pp. 164-170
-
-
Bowie, J.U.1
Lüthy, R.2
Eisenberg, D.3
-
14
-
-
0025398721
-
WHAT IF: Molecular modeling and drug design program
-
Vriend G. WHAT IF: molecular modeling and drug design program. J Mol Graphics 1990;8:52-56.
-
(1990)
J Mol Graphics
, vol.8
, pp. 52-56
-
-
Vriend, G.1
-
15
-
-
0028300741
-
Combining evolutionary information and neural networks to predict protein secondary structure
-
Rost B, Sander C. Combining evolutionary information and neural networks to predict protein secondary structure. Proteins 1994;19:55-72.
-
(1994)
Proteins
, vol.19
, pp. 55-72
-
-
Rost, B.1
Sander, C.2
-
18
-
-
0029664589
-
The 2.0 Å crystal structure of a heterotrimeric G protein
-
Lambright DG, Sondek J, Bohm A, Skiba NP, Hamm HE, Sigler PB. The 2.0 Å crystal structure of a heterotrimeric G protein. Nature 1996;379:311-319.
-
(1996)
Nature
, vol.379
, pp. 311-319
-
-
Lambright, D.G.1
Sondek, J.2
Bohm, A.3
Skiba, N.P.4
Hamm, H.E.5
Sigler, P.B.6
-
19
-
-
0032516098
-
Light-activated rhodopsin induces structural binding motif in G protein a subunit
-
Kisselev OG, Kao J, Ponder JW, Fann YC, Gautam N, Marshall G.R. Light-activated rhodopsin induces structural binding motif in G protein a subunit. Proc Natl Acad Sci USA 1998;95:4270-4275.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 4270-4275
-
-
Kisselev, O.G.1
Kao, J.2
Ponder, J.W.3
Fann, Y.C.4
Gautam, N.5
Marshall, G.R.6
-
20
-
-
0026124585
-
Electrostatics and diffusion of molecules in solutions: Simulations with the University of Houston Brownian dynamics program
-
Devis E, Madura JD, Luty BA, Mc Cammon JA. Electrostatics and diffusion of molecules in solutions: simulations with the University of Houston Brownian Dynamics Program. J Comp Phys Commun 1990;62:187-197.
-
(1990)
J Comp Phys Commun
, vol.62
, pp. 187-197
-
-
Devis, E.1
Madura, J.D.2
Luty, B.A.3
Mc Cammon, J.A.4
-
21
-
-
33645941402
-
The OPLS potential functions for proteins: Energy minimizations for crystal of cyclic peptides and crambins
-
Jorgensen WL, Tirado-Rives J. The OPLS potential functions for proteins: energy minimizations for crystal of cyclic peptides and crambins. J Am Chem Soc 1988;110:1657-1666.
-
(1988)
J Am Chem Soc
, vol.110
, pp. 1657-1666
-
-
Jorgensen, W.L.1
Tirado-Rives, J.2
-
22
-
-
0030855390
-
ESCHER: A new docking procedure applied to the reconstruction of protein tertiary structure
-
Ausiello G, Cesareni G, Helmer-Citterich M. ESCHER: a new docking procedure applied to the reconstruction of protein tertiary structure. Proteins 1997;28:556-567.
-
(1997)
Proteins
, vol.28
, pp. 556-567
-
-
Ausiello, G.1
Cesareni, G.2
Helmer-Citterich, M.3
-
23
-
-
0001209788
-
Suggested binding mechanism of the HIV-gp120 to its CD4 receptor
-
Székely Z, Kònya Z, Becskei A, et al. Suggested binding mechanism of the HIV-gp120 to its CD4 receptor. J Mol Struct (Theochem) 1996;367:159-186.
-
(1996)
J Mol Struct (Theochem)
, vol.367
, pp. 159-186
-
-
Székely, Z.1
Kònya, Z.2
Becskei, A.3
-
24
-
-
84962439356
-
Roles of electrostatic interaction in proteins
-
and references therein
-
Nakamura H. Roles of electrostatic interaction in proteins. Q Rev Biophys 1996;29:1-90 and references therein.
-
(1996)
Q Rev Biophys
, vol.29
, pp. 1-90
-
-
Nakamura, H.1
-
25
-
-
0028291136
-
Receptor binding properties of four-helix-bundle growth factors deduced from electrostatic analysis
-
and references therein
-
Demchuk E, Mueller T, Oschkinat H, Sebald W, Wade RC. Receptor binding properties of four-helix-bundle growth factors deduced from electrostatic analysis. Protein Sci 1994;3:920-935 and references therein.
-
(1994)
Protein Sci
, vol.3
, pp. 920-935
-
-
Demchuk, E.1
Mueller, T.2
Oschkinat, H.3
Sebald, W.4
Wade, R.C.5
-
26
-
-
0029873697
-
Rapid, electrostatically assisted association of proteins
-
Schreiber G, Fersht AR. Rapid, electrostatically assisted association of proteins. Nat Struct Biol 1996;3:427-431.
-
(1996)
Nat Struct Biol
, vol.3
, pp. 427-431
-
-
Schreiber, G.1
Fersht, A.R.2
-
27
-
-
0028860268
-
Heterotrimeric G proteins: Organizers of transmembrane signals
-
Neer E. Heterotrimeric G proteins: organizers of transmembrane signals. Cell 1995;80:249-257.
-
(1995)
Cell
, vol.80
, pp. 249-257
-
-
Neer, E.1
-
28
-
-
0027132717
-
The 2.2 Å crystal structure of transducin-α complexed with GTPγS
-
Noel JP, Hamm HE, Sigler PB. The 2.2 Å crystal structure of transducin-α complexed with GTPγS. Nature 1993;366:654-663.
-
(1993)
Nature
, vol.366
, pp. 654-663
-
-
Noel, J.P.1
Hamm, H.E.2
Sigler, P.B.3
-
29
-
-
0026774642
-
Promotion of the GTP-liganded state of the Goα protein by deletion of the C terminus
-
Denker BM, Schmidt CJ, Neer EJ. Promotion of the GTP-liganded state of the Goα protein by deletion of the C terminus. J Biol Chem 1992;267:9998-10002.
-
(1992)
J Biol Chem
, vol.267
, pp. 9998-10002
-
-
Denker, B.M.1
Schmidt, C.J.2
Neer, E.J.3
-
30
-
-
0028588656
-
Cellular signaling by an agonist-activated receptor Gsα fusion protein
-
Bertin B, Freissmuth M, Jockers R, Strosberg D, Marullo, S. Cellular signaling by an agonist-activated receptor Gsα fusion protein. Proc Natl Acad Sci USA 1994;91:8827-8831.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8827-8831
-
-
Bertin, B.1
Freissmuth, M.2
Jockers, R.3
Strosberg, D.4
Marullo, S.5
-
31
-
-
0031437841
-
Measurement of agonist efficacy using an α2A-adrenoceptor-Gi1α fusion protein
-
Wise A, Carr CI, Groarke DA, Milligan G. Measurement of agonist efficacy using an α2A-adrenoceptor-Gi1α fusion protein. FEBS Lett 1997;419:141-146.
-
(1997)
FEBS Lett
, vol.419
, pp. 141-146
-
-
Wise, A.1
Carr, C.I.2
Groarke, D.A.3
Milligan, G.4
-
32
-
-
0031708411
-
Binding of transducin and transducin-derived peptides to rhodopsin studied by ATR-FTIR difference spectroscopy
-
Fahmy K. Binding of transducin and transducin-derived peptides to rhodopsin studied by ATR-FTIR difference spectroscopy. Biophys J 1998;75:1306-1318.
-
(1998)
Biophys J
, vol.75
, pp. 1306-1318
-
-
Fahmy, K.1
-
33
-
-
0032510948
-
Antagonists of the receptor-G protein interface block Gi-coupled signal transduction
-
Gilchrist A, Mazzoni MR, Dineen B, et al. Antagonists of the receptor-G protein interface block Gi-coupled signal transduction. Biol Chem 1998;273:14912-14919.
-
(1998)
Biol Chem
, vol.273
, pp. 14912-14919
-
-
Gilchrist, A.1
Mazzoni, M.R.2
Dineen, B.3
-
34
-
-
0029664921
-
Evolutionarily conserved Gαβγ binding surfaces support a model of the G protein-receptor complex
-
Lichtarge O, Bourne HR, Cohen FE. Evolutionarily conserved Gαβγ binding surfaces support a model of the G protein-receptor complex. Proc Natl Acad Sci USA 1996;93:7507-7511.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7507-7511
-
-
Lichtarge, O.1
Bourne, H.R.2
Cohen, F.E.3
-
35
-
-
0028101036
-
Synthetic peptides as probes for G protein function
-
Rasenick MM, Watanabe M, Lazarevic MB, Hatta S, Hamm HE. Synthetic peptides as probes for G protein function. J Biol Chem 1994;269:21519-21525.
-
(1994)
J Biol Chem
, vol.269
, pp. 21519-21525
-
-
Rasenick, M.M.1
Watanabe, M.2
Lazarevic, M.B.3
Hatta, S.4
Hamm, H.E.5
-
36
-
-
0030043913
-
Potent peptide analogues of a G protein receptor-binding region obtained with a combinatorial library
-
Martin EL, Rens-Domiano S, Schatz PJ, Hamm HE. Potent peptide analogues of a G protein receptor-binding region obtained with a combinatorial library. J Biol Chem 1996;271:361-366.
-
(1996)
J Biol Chem
, vol.271
, pp. 361-366
-
-
Martin, E.L.1
Rens-Domiano, S.2
Schatz, P.J.3
Hamm, H.E.4
-
37
-
-
0029969175
-
Interaction of transducin with light-activated rhodopsin protects it from proteolytic digestion by trypsin
-
Mazzoni M, Hamm HE. Interaction of transducin with light-activated rhodopsin protects it from proteolytic digestion by trypsin. J Biol Chem 1996;271: 30034-30040.
-
(1996)
J Biol Chem
, vol.271
, pp. 30034-30040
-
-
Mazzoni, M.1
Hamm, H.E.2
-
38
-
-
0030614427
-
Receptor and βγ binding sites in the α subunit of the retinal G protein transducin
-
Onrust R, Herzmark P, Chi P, et al. Receptor and βγ binding sites in the α subunit of the retinal G protein transducin. Science 1997;275:381-384.
-
(1997)
Science
, vol.275
, pp. 381-384
-
-
Onrust, R.1
Herzmark, P.2
Chi, P.3
-
40
-
-
0030903692
-
Conditional activation defect of a human Gsα mutant
-
Iiri T, Farfel Z, Bourne HR. Conditional activation defect of a human Gsα mutant. Proc Natl Acad Sci USA 1997;94: 5656-5661.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5656-5661
-
-
Iiri, T.1
Farfel, Z.2
Bourne, H.R.3
-
41
-
-
0032544633
-
The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling
-
Burstein ES, Spalding TA, Brann MR. The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling. J Biol Chem 1998;273:24322-24327.
-
(1998)
J Biol Chem
, vol.273
, pp. 24322-24327
-
-
Burstein, E.S.1
Spalding, T.A.2
Brann, M.R.3
-
42
-
-
0001107340
-
Structure/function relationships of a G-protein coupling pocket formed by the third intracellular loop of the m5 muscarinic receptor
-
Burstein ES, Spalding TA, Brann MR. Structure/function relationships of a G-protein coupling pocket formed by the third intracellular loop of the m5 muscarinic receptor. Biochemistry 1998;37:4052-4058.
-
(1998)
Biochemistry
, vol.37
, pp. 4052-4058
-
-
Burstein, E.S.1
Spalding, T.A.2
Brann, M.R.3
-
43
-
-
0025212680
-
Regions of the α1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function
-
Cotecchia S, Exum S, Caron MG, Lefkowitz R. Regions of the α1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function. Proc Natl Acad Sci USA 1990;87:2896-2900.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 2896-2900
-
-
Cotecchia, S.1
Exum, S.2
Caron, M.G.3
Lefkowitz, R.4
|