Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis

Carcinogenesis

Volumn 18, Issue 2, 1997, Pages 321-327

  Smits, Ron ^a   Kartheuser, Alex ^b   Jagmohan Changur, Shantie ^a   Leblanc, Veronique ^a   Breukel, Cor ^a   De Vries, Anja ^c   Van Kranen, Henk ^c   Van Krieken, J Han ^a   Williamson, Sophia ^d   Edelmann, Winfried ^e   Kucherlapati, Raju ^e   Meera Khan, P ^a   Fodde, Riccardo ^a,f  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ADENOCARCINOMA; ADENOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER MODEL; CHROMOSOME 18; CHROMOSOME LOSS; COLON POLYPOSIS; IMMUNOHISTOCHEMISTRY; INTESTINE TUMOR; MOUSE; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; ADENOMA; ANIMALS; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 18; GENES, APC; GENES, P53; GENES, RAS; HUMANS; INTESTINAL NEOPLASMS; INTESTINE, SMALL; MICE; MICE, INBRED C57BL;

EID: 0031408413     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/18.2.321     Document Type: Article

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