Regulation of cyclooxygenase-2 by nitric oxide in activated hepatic macrophages during acute endotoxemia

Journal of Leukocyte Biology

Volumn 71, Issue 6, 2002, Pages 1005-1011

  Ahmad, Nosheen ^a   Chen, Li C ^a   Gordon, Marion A ^a   Laskin, Jeffrey D ^a   Laskin, Debra L ^a,b  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Kupffer cells; Liver; NOSII; PGE 2

Indexed keywords

AMINOGUANIDINE; CYCLOOXYGENASE 2; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN E2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENDOTOXEMIA; ENZYME ACTIVITY; FEMALE; KUPFFER CELL; MACROPHAGE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE INJURY; WESTERN BLOTTING;

ACUTE DISEASE; ANIMALS; CELLS, CULTURED; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; ENDOTOXEMIA; ENDOTOXINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GUANIDINES; ISOENZYMES; KUPFFER CELLS; LIPOPOLYSACCHARIDES; LIVER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ANIMALIA;

EID: 0036623149     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (65)

1. Pilaro, A. M., Laskin, D. L. (1986) Accumulation of activated mononuclear phagocytes in the liver following lipopolysaccharide treatment of rats. J. Leukoc. Biol. 40, 29-41.
2. Nolan, J. (1975) The role of endotoxin in liver injury. Gastroenterology 69, 1346-1356.
3. Hirata, K., Kaneko, A., Ogawa, K., Hayasaka, H., Onoe, E. (1980) Effect of endotoxin on rat liver. Lab. Investig. 43, 165-171.
4. 2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo. J. Exp. Med. 184, 883-891.
5. G-methyl-L-arginine, an inhibitor of nitric oxide synthesis. Biochem. Biophys. Res. Commun. 172, 1132-1138.
6. Weinberg, J. B. (2000) Nitric oxide synthase 2 and cyclooxygenase 2 interactions in inflammation. Immunol. Res. 22, 319-341.
7. Salvemini, D., Misko, T. P., Masferrer, J., Seibert, K., Currie, M. G., Needleman, P. (1993) Nitric oxide activates cyclooxygenase enzymes. Proc. Natl. Acad. Sci. USA 90, 7240-7244.
8. 2 biosynthesis in macrophages. J. Leukoc. Biol. 65, 792-799.
9. Devauz, Y., Seguin, C., Grosjean, S., de Talance, N., Camaeti, V., Burlet, A., Zannad, F., Meistelman, C., Mertes, P. M., Longrois, D. (2001) Lipopolysaccharide-induced increase of prostaglandin E(2) is mediated by inducible nitric oxide synthase activation of the constitutive cyclooxygenase and induction of membrane-associated prostaglandin E synthase. J. Immunol. 167, 3962-3971.
10. Salvemini, D., Settle, S. L., Masferrer, J. L., Seibert, K., Currie, M. G., Needleman, P. (1995) Regulation of prostaglandin production by nitric oxide; an in vivo analysis. Br. J. Pharmacol. 114, 1171-1178.
11. Sautebin, L., Ialenti, A., Ianaro, A., Di Rosa, M. (1995) Modulation by nitric oxide of prostaglandin biosynthesis in the rat. Br. J. Pharmacol. 114, 323-328.
12. Lianos, E. A., Guglielmi, K., Sharma, M. (1998) Regulatory interactions between inducible nitric oxide synthase and eicosanoids in glomerular immune injury. Kidney Int. 53, 645-653.
13. Franchi, A. M., Chaud, M., Rettori, V., Suburo, A., McCann, S. M., Gimeno, M. (1994) Role of nitric oxide in eicosanoid synthesis and uterine motility in estrogen-treated rat uteri. Proc. Natl. Acad. Sci. USA 91, 539-543.
14. 2 release from the hypothalamus. Proc. Natl. Acad. Sci. USA 89, 11543-11546.
15. Davidge, S. T., Baker, P. N., McLaughlin, M. K., Roberts, J. M. (1995) Nitric oxide produced by endothelial cells increases production of eicosanoids through activation of prostaglandin H synthase. Circ. Res. 77, 274-283.
16. Watkins, D. N., Garlepp, M. J., Thompson, P. J. (1997) Regulation of the inducible cyclooxygenase pathway in human cultured airway epithelial (A549) cells by nitric oxide. Br. J. Pharmacol. 121, 1482-1488.
17. Salvemini, D., Seibert, K., Masferrer, J. L., Misko, T. P., Currie, M. G., Needleman, P. (1994) Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. J. Clin. Investig. 93, 1940-1947.
18. Swierkosz, T. A., Mitchell, J. A., Warner, T. D., Botting, R. M., Vane, J. (1995) Co-induction of nitric oxide synthase and cyclooxygenase: interactions between nitric oxide and prostanoids. Br. J. Pharmacol. 114, 1335-1342.
19. Habib, A., Bernard, C., Lebret, M., Creminon, C., Esposito, B., Tedgui, A., Maclouf, J. (1997) Regulation of the expression of cyclooxygenase-2 by nitric oxide in rat peritoneal macrophages. J. Immunol. 158, 3845-3851.
20. Amin, A. R., Attur, M., Patel, R. N., Thakker, G. D., Marshall, P. J., Rediske, J., Stuchin, S. A., Patel, I. R., Abramson, S. B. (1997) Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide. J. Clin. Investig. 99, 1231-1237.
21. Marotta, P., Sautebin, L., Di Rosa, M. (1992) Modulation of the induction of nitric oxide synthase by eicosanoids in the murine macrophage cell line J774. Br. J. Pharmacol. 107, 640-641.
22. Levi, G., Minghetti, L., Aloisi, F. (1998) Regulation of prostanoid synthesis in microglial cells and effects of prostaglandin E2 on microglial functions. Biochimie 80, 899-904.
23. Pang, L., Hoult, J. R. (1997) Repression of inducible nitric oxide synthase and cyclooxygenase-2 by prostaglandin E2 and other cyclic AMP stimulants in J774 macrophages. Biochem. Pharmacol. 53, 493-500.
24. Tetsuka, T., Daphna-Iken, D., Srivastava, S. K., Baier, L. D., DuMaine, J., Morrison, A. R. (1994) Cross-talk between cyclooxygenase and nitric oxide pathways: prostaglandin E2 negatively modulates induction of nitric oxide synthase by interleukin 1. Proc. Natl. Acad. Sci. USA 91, 12168-12172.
25. Harbrecht, B., McClure, E. A., Simmons, R. L., Billiar, T. R. (1995) Prostanoids inhibit Kupffer cell nitric oxide synthesis. J. Surg. Res. 58, 625-629.
26. Chen, C. C., Chen, Y. H., Lin, W. W. (1999) Role of the cyclic AMP-protein kinase A pathway in lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages. J. Biol. Chem. 274, 31559-31564.
27. McCloskey, T. W., Todaro, J., Laskin, D. L. (1992) Lipopolysaccharide treatment of rats alters antigen expression and oxidative metabolism in hepatic macrophages and endothelial cells. Hepatology 16, 191-203.
28. Feder, L. S., Laskin, D, L. (1994) Regulation of hepatic endothelial cell and macrophage proliferation and nitric oxide production by GM-CSF, M-CSF, and IL-1β following acute endotoxemia. J. Leukoc. Biol. 55, 507-513.
29. 15N nitrate in biological fluids. Anal. Biochem. 126, 131-138.
30. Nilsson, B. O. (1999) Biological effects of aminoguanidine: an update. Inflamm. Res. 48, 509-515.
31. Laskin, D. L., Heck, D. E., Gardner, C. R., Feder, L. S., Laskin, J. D. (1994) Distinct patterns of nitric oxide production in hepatic macrophages and endothelial cells following acute exposure of rats to endotoxin. J. Leukoc. Biol. 56, 751-758.
32. Laskin, D. L., Rodriguez del Valle, M., Heck, D. E., Hwang, S., Ohnishi, S. T., Durham, S, K., Goller, N. L., Laskin, J. D. (1995) Hepatic nitric oxide production following acute endotoxemia in rats is mediated by increased inducible nitric oxide synthase gene expression. Hepatology 22, 223-234.
33. Nathan, C. F. (1987) Secretory products of macrophages. J. Clin. Investig. 79, 319-326.
34. Laskin, D. L., Laskin, J. D. (1997) Phagocytes. In Comprehensive Toxicology, Vol. 5, Toxicology of the Immune System (D. A. Lawrence, ed.), New York, Pergamon, 97-112.
35. Decker, K. (1990) Biologically active products of stimulated liver macrophages (Kupffer cells). Eur. J. Biochem. 192, 245-261.
36. Wink, D. A., Mitchell, J. B. (1998) Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide. Free Radic. Biol. Med. 25, 434-456.
37. Clemens, M. G. (1999) Nitric oxide in liver injury. Hepatology 30, 1-5.
38. Katori, M., Majima, M. (2000) Cyclooxygenase-2: its rich diversity of roles and possible application of its selective inhibitors. Inflamm. Res. 49, 367-392.
39. Dinchuck, J. E., Car, B. D., Focht, R. J., Johnston, J. J., Jaffee, B. D., Covington, M. B., Contel, N. R., Eng, V. M., Collins, R. J., Czerniak, P. M. (1995) Renal abnormalities and altered inflammatory response in mice lacking cyclooxygenase-2. Nature 378, 406-409.
40. Hierholzer, C., Harbrecht, B., Menezes, J. M., Kane, J., MacMicking. J., Nathan, C. F., Peitzman, A. B., Billiar, T. R., Tweardy, D. J. (1998) Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock. J. Exp. Med. 187, 917-928.
41. MacMicking, J., Nathan, C. F., Hom, G., Chartrain, N., Fletcher, D. S., Trumbaur, M., Stevens, K., Xie, Q., Sokol, K., Hutchinson, N., Chen, H., Mudgett, J. S. (1995) Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 81, 641-650.
42. Mateo, A. O., Aleixandre de Arti Nsno, M. A. (2000) Nitric oxide reactivity and mechanisms involved in its biological effects. Pharmacol. Res. 42, 421-427.
43. Bowers, G. J., MacVittie, T. J., Hirsch, E. F., Conklin, J. C., Nelson, R. D., Roethel, R. J., Fink, M. P. (1985) Prostanoid production by lipopolysaccharide-stimulated Kupffer cells. J. Surg. Res. 38, 501-508.
44. Dieter, P., Ambs, P., Fitzke, E., Hidaka, H., Hoffmann, R., Schwende, H. (1995) Comparative studies of cytotoxicity and the release of TNF-α, nitric oxide, and eicosanoids of liver macrophages treated with lipopolysaccharide and liposome-encapsulated MTP-PE. J. Immunol. 155, 2595-2604.
45. 2 production and modulates immune function. J. Surg. Res. 78, 1-6.
46. Roland, C. R., Naziruddin, B., Mohanakumar, T., Flye, M. W. (1996) Gadolinium chloride inhibits Kupffer cell nitric oxide synthase (iNOS) induction. J. Leukoc. Biol. 60, 487-492.
47. Mustafa, S. B., Olson, M. S. (1999) Effects of calcium channel antagonists on LPS-induced hepatic iNOS expression. Am. J. Physiol. 277, G351-G360.
48. 2 is involved in alcohol-induced fat accumulation in rat liver. Am. J. Physiol. 279, G100-G106.
49. Gardner, C. R., Dambach, D. M., Durham, S. K., Cohen, S. D., Bruno, M. K., Salzman, A. L., Southan, G. J., Laskin, D. L. (2000) Role of peroxynitrite (PN) in acetaminophen (AA)-induced hepatotoxicity. The Toxicologist 54, 41.
50. Rockey, D. C., Chung, J. J. (1997) Regulation of inducible nitric oxide synthase and nitric oxide during hepatic injury and fibrogenesis. Am. J. Physiol. 273, G124-G130.
51. Dieter, P., Scheibe, R., Jakobsson, P. J., Watanabe, K., Kolada, A., Kamionka, S. (2000) Functional coupling of cyclooxygenase 1 and 2 to discrete prostanoid synthases in liver macrophages. Biochem. Biophys. Res. Commun. 276, 488-492.
52. Stadler, J., Harbrecht, B., DiSilvio, M., Curran, R. D., Jordan, M. L., Simmons, R. L., Billiar, T. R. (1993) Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells. J. Leukoc. Biol. 53, 165-172.
53. Smith, W. L., DeWitt, D. L., Garavito, R. M. (2000) Cyclooxygenases: structural, cellular, and molecular biology. Annu. Rev. Biochem. 69, 145-182.
54. Shepherd, V. L. (1991) Cytokine receptors of the lung. Am. J. Respir. Cell Mol. Biol. 5, 403-410.
55. DeGeorge, G. L., Heck, D. E., Laskin, J. D. (1997) Arginine metabolism in keratinocytes and macrophages during nitric oxide biosynthesis: multiple modes of action of nitric oxide synthase inhibitors. Biochem. Pharmacol. 54, 103-112.
56. 2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells. FEBS Lett. 413, 314-318.
57. Landino, L. M., Crews, B. C., Timmons, M. D, Morrow, J. D., Marnett, L. J. (1996) Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis. Proc. Natl. Acad. Sci. USA 93, 15069-15074.
58. Griffon, B., Cillard, J., Chevanne, M., Morel, I., Cillard, P., Sergent, O. (1998) Macrophage-induced inhibition of nitric oxide production in primary rat hepatocyte cultures via prostaglandin E2 release. Hepatology 28, 1300-1308.
59. Misko, T. P., Trotter, J. L., Cross, A. H. (1995) Mediation of inflammation by encephalitogenic cells: interferon γ induction of nitric oxide synthase and cyclooxygenase 2. J. Neuroimmunol. 61, 195-204.
60. Tetsuka, T., Daphna-Iken, D., Miller, B. W., Guan, Z., Baier, L. D., Morrison, A. R. (1996) Nitric oxide amplifies interleukin 1-induced cyclooxygenase-2 expression in rat mesangial cells. J. Clin. Investig. 97, 2051-2056.
61. Marnett, L. J., Wright, T L., Crews, B. C., Tannenbaum, S. R., Morrow, J. D. (2000) Regulation of prostaglandin biosynthesis by nitric oxide is revealed by targeted deletion of inducible nitric oxide synthase. J. Biol. Chem. 275, 13427-13430.
62. Goodwin, D. C., Landino, L. M., Marnett, L. J. (1999) Effects of nitric oxide and nitric oxide-derived species on prostaglandin endoperoxide synthase and prostaglandin biosynthesis. FASEB J. 13, 1121-1136.
63. 2. J. Leukoc. Biol. 61, 712-720.
64. 2 regulates inducible nitric oxide synthase in the murine macrophage cell line J774. Prostaglandins 49, 105-115.
65. Posadas, I., Terencio, M. C., Guillen, I., Ferrandiz, M. L., Coloma, J., Paya, M., Alcaraz, M. J. (2000) Co-regulation between cyclooxygenase-2 and inducible nitric oxide synthase expression in the time-course of murine inflammation. Naunyn-Schmiedeberg's Arch. Pharmacol. 361, 98-106.