-
1
-
-
54249116230
-
Genetic regulatory mechanisms in the synthesis of proteins
-
Jacob, F. and Monod, J. (1961) Genetic regulatory mechanisms in the synthesis of proteins. J. Mol. Biol. 3, 318-356.
-
(1961)
J. Mol. Biol
, vol.3
, pp. 318-356
-
-
Jacob, F.1
Monod, J.2
-
2
-
-
73649152457
-
Allosteric proteins and cellular control systems
-
Monod, J., Changeux J.-P. and Jacob, F. (1963) Allosteric proteins and cellular control systems. J. Mol. Biol. 6, 306-329.
-
(1963)
J. Mol. Biol
, vol.6
, pp. 306-329
-
-
Monod, J.1
Changeux, J.-P.2
Jacob, F.3
-
4
-
-
0014413858
-
On the assay, isolation, and characterization of the lac repressor
-
Riggs, A. D. and Bourgeois, S. (1968) On the assay, isolation, and characterization of the lac repressor. J. Mol. Biol. 34, 361-364.
-
(1968)
J. Mol. Biol
, vol.34
, pp. 361-364
-
-
Riggs, A.D.1
Bourgeois, S.2
-
6
-
-
0014413868
-
DNA binding of the lac repressor
-
Riggs, A. D., Bourgeois, S., Newby, R. F. and Cohn, M. (1968) DNA binding of the lac repressor. J. Mol. Biol. 34, 365-368.
-
(1968)
J. Mol. Biol
, vol.34
, pp. 365-368
-
-
Riggs, A.D.1
Bourgeois, S.2
Newby, R.F.3
Cohn, M.4
-
7
-
-
0014966123
-
lac repressor-operator interaction. II. Effect of galactosides and other ligands
-
Riggs, A. D., Newby, R. F. and Bourgeois, S. (1970) lac repressor-operator interaction. II. Effect of galactosides and other ligands. J. Mol. Biol. 51, 303-314.
-
(1970)
J. Mol. Biol
, vol.51
, pp. 303-314
-
-
Riggs, A.D.1
Newby, R.F.2
Bourgeois, S.3
-
8
-
-
0015527295
-
lac repressor-operator interaction. VI. The natural inducer of the lac operon
-
Jobe, A. and Bourgeois, S. (1972) lac repressor-operator interaction. VI. The natural inducer of the lac operon. J. Mol. Biol. 69, 397-408.
-
(1972)
J. Mol. Biol
, vol.69
, pp. 397-408
-
-
Jobe, A.1
Bourgeois, S.2
-
9
-
-
0031961672
-
Lactose repressor protein: Functional properties and structure
-
Matthews, K. S. and Nichols, J. C. (1998) Lactose repressor protein: functional properties and structure. Prog. Nucl. Acid Res. Mol. Biol. 58, 127-164.
-
(1998)
Prog. Nucl. Acid Res. Mol. Biol
, vol.58
, pp. 127-164
-
-
Matthews, K.S.1
Nichols, J.C.2
-
10
-
-
20444411150
-
The lac repressor
-
Lewis, M. (2005) The lac repressor. C. R. Biol. 328, 521-548.
-
(2005)
C. R. Biol
, vol.328
, pp. 521-548
-
-
Lewis, M.1
-
11
-
-
0004237567
-
-
2nd Edn, Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y
-
Miller, J. H. and Reznikoff, W. S. (1980) The Operon, 2nd Edn., Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
-
(1980)
The Operon
-
-
Miller, J.H.1
Reznikoff, W.S.2
-
13
-
-
0035253082
-
The Lac repressor: A second generation of structural and functional studies
-
Bell, C. E. and Lewis, M. (2001) The Lac repressor: a second generation of structural and functional studies. Curr. Opin. Struct. Biol. 11, 19-25.
-
(2001)
Curr. Opin. Struct. Biol
, vol.11
, pp. 19-25
-
-
Bell, C.E.1
Lewis, M.2
-
14
-
-
0015757986
-
The nucleotide sequence of the lac operator
-
Gilbert, W. and Maxam, A. (1973) The nucleotide sequence of the lac operator. Proc. Natl. Acad. Sci. USA 70, 3581-3584.
-
(1973)
Proc. Natl. Acad. Sci. USA
, vol.70
, pp. 3581-3584
-
-
Gilbert, W.1
Maxam, A.2
-
15
-
-
0014965617
-
lac repressor-operator interaction. I. Equilibrium studies
-
Riggs, A. D., Suzuki, H. and Bourgeois, S. (1970) lac repressor-operator interaction. I. Equilibrium studies. J. Mol. Biol. 48, 67-83.
-
(1970)
J. Mol. Biol
, vol.48
, pp. 67-83
-
-
Riggs, A.D.1
Suzuki, H.2
Bourgeois, S.3
-
16
-
-
0028960228
-
Inhibition of transcription initiation by lac repressor
-
Schlax, P. J., Capp, M. W. and Record, M. T. Jr (1995) Inhibition of transcription initiation by lac repressor. J. Mol. Biol. 245, 331-350.
-
(1995)
J. Mol. Biol
, vol.245
, pp. 331-350
-
-
Schlax, P.J.1
Capp, M.W.2
Record Jr, M.T.3
-
17
-
-
0025893167
-
lac repressor acts by modifying the initial transcribing complex so that it cannot leave the promoter
-
Lee, J. and Goldfarb, A. (1991) lac repressor acts by modifying the initial transcribing complex so that it cannot leave the promoter. Cell 66, 793-798.
-
(1991)
Cell
, vol.66
, pp. 793-798
-
-
Lee, J.1
Goldfarb, A.2
-
18
-
-
0023644260
-
Lac repressor is a transient gene-activating protein
-
Straney, S. B. and Crothers, D. M. (1987) Lac repressor is a transient gene-activating protein. Cell 51, 699-707.
-
(1987)
Cell
, vol.51
, pp. 699-707
-
-
Straney, S.B.1
Crothers, D.M.2
-
19
-
-
0019205865
-
Genetic analysis of transpositions in the lac region of Escherichia coli
-
Miller, J. H., Calos, M. P., Galas, D., Hofer, M., Büchel, D. E. and Müller-Hill, B. (1980) Genetic analysis of transpositions in the lac region of Escherichia coli. J. Mol. Biol. 144, 1-18.
-
(1980)
J. Mol. Biol
, vol.144
, pp. 1-18
-
-
Miller, J.H.1
Calos, M.P.2
Galas, D.3
Hofer, M.4
Büchel, D.E.5
Müller-Hill, B.6
-
20
-
-
20444369900
-
The lac operon galactoside acetyltransferase
-
Roderick, S. L. (2005) The lac operon galactoside acetyltransferase. C. R. Biol. 328, 568-575.
-
(2005)
C. R. Biol
, vol.328
, pp. 568-575
-
-
Roderick, S.L.1
-
22
-
-
0035846526
-
A structural view of the action of Escherichia coli (lacZ) beta-galactosidase
-
Juers, D. H., Heightman, T. D., Vasella, A., McCarter, J. D., Mackenzie, L., Withers, S. G. and Matthews, B. W. (2001) A structural view of the action of Escherichia coli (lacZ) beta-galactosidase. Biochemistry 40, 14781-14794.
-
(2001)
Biochemistry
, vol.40
, pp. 14781-14794
-
-
Juers, D.H.1
Heightman, T.D.2
Vasella, A.3
McCarter, J.D.4
Mackenzie, L.5
Withers, S.G.6
Matthews, B.W.7
-
23
-
-
0016745534
-
Interaction of effecting ligands with lac repressor and repressor-operator complex
-
Barkley, M. D., Riggs, A. D., Jobe, A. and Bourgeois, S. (1975) Interaction of effecting ligands with lac repressor and repressor-operator complex. Biochemistry 14, 1700-1712.
-
(1975)
Biochemistry
, vol.14
, pp. 1700-1712
-
-
Barkley, M.D.1
Riggs, A.D.2
Jobe, A.3
Bourgeois, S.4
-
24
-
-
0027236999
-
Transcriptional regulation by cAMP and its receptor protein
-
Kolb, A., Busby, S., Buc, H., Garges, S. and Adhya, S. (1993) Transcriptional regulation by cAMP and its receptor protein. Annu. Rev. Biochem. 62, 749-795.
-
(1993)
Annu. Rev. Biochem
, vol.62
, pp. 749-795
-
-
Kolb, A.1
Busby, S.2
Buc, H.3
Garges, S.4
Adhya, S.5
-
25
-
-
0014799069
-
Cyclic AMP receptor protein of E. coli: Its role in the synthesis of inducible enzymes
-
Emmer, M., deCrombrugghe, B., Pastan, I. and Perlman, R. (1970) Cyclic AMP receptor protein of E. coli: its role in the synthesis of inducible enzymes. Proc. Natl. Acad. Sci. USA 66, 480-487.
-
(1970)
Proc. Natl. Acad. Sci. USA
, vol.66
, pp. 480-487
-
-
Emmer, M.1
deCrombrugghe, B.2
Pastan, I.3
Perlman, R.4
-
26
-
-
0016150348
-
The location of the repressor binding sites in the lac operon
-
Reznikoff, W. S., Winter, R. B. and Hurley, C. K. (1974) The location of the repressor binding sites in the lac operon. Proc. Natl. Acad. Sci. USA 71, 2314-2318.
-
(1974)
Proc. Natl. Acad. Sci. USA
, vol.71
, pp. 2314-2318
-
-
Reznikoff, W.S.1
Winter, R.B.2
Hurley, C.K.3
-
27
-
-
0018800287
-
Second' and 'third operator' of the lac operon: An investigation of their role in the regulatory mechanism
-
Pfahl, M., Gulde, V. and Bourgeois, S. (1979) 'Second' and 'third operator' of the lac operon: an investigation of their role in the regulatory mechanism. J. Mol. Biol. 127, 339-344.
-
(1979)
J. Mol. Biol
, vol.127
, pp. 339-344
-
-
Pfahl, M.1
Gulde, V.2
Bourgeois, S.3
-
28
-
-
0022529619
-
Upstream operators enhance repression of the lac promoter
-
Mossing, M. C. and Record, M. T. Jr (1986) Upstream operators enhance repression of the lac promoter. Science 233, 889-892.
-
(1986)
Science
, vol.233
, pp. 889-892
-
-
Mossing, M.C.1
Record Jr, M.T.2
-
29
-
-
0022729012
-
Synthetic lac operator mediates repression through lac repressor when introduced upstream and downstream from lac promoter
-
Besse, M., von Wilcken-Bergmann, B. and Müller-Hill, B. (1986) Synthetic lac operator mediates repression through lac repressor when introduced upstream and downstream from lac promoter. EMBO J. 5, 1377-1381.
-
(1986)
EMBO J
, vol.5
, pp. 1377-1381
-
-
Besse, M.1
von Wilcken-Bergmann, B.2
Müller-Hill, B.3
-
30
-
-
0025874018
-
Stability of a Lac repressor mediated 'looped complex'
-
Brenowitz, M., Pickar, A. and Jamison, E. (1991) Stability of a Lac repressor mediated 'looped complex'. Biochemistry 30, 5986-5998.
-
(1991)
Biochemistry
, vol.30
, pp. 5986-5998
-
-
Brenowitz, M.1
Pickar, A.2
Jamison, E.3
-
31
-
-
0023645101
-
DNA supercoiling promotes formation of a bent repression loop in lac DNA
-
Borowiec, J. A., Zhang, L., Sasse-Dwight, S. and Gralla, J. D. (1987) DNA supercoiling promotes formation of a bent repression loop in lac DNA. J. Mol. Biol. 196, 101-111.
-
(1987)
J. Mol. Biol
, vol.196
, pp. 101-111
-
-
Borowiec, J.A.1
Zhang, L.2
Sasse-Dwight, S.3
Gralla, J.D.4
-
32
-
-
19444387811
-
Bacterial repression loops require enhanced DNA flexibility
-
Becker, N. A., Kahn, J. D. and Maher III, L. J., (2005) Bacterial repression loops require enhanced DNA flexibility. J. Mol. Biol. 349, 716-730.
-
(2005)
J. Mol. Biol
, vol.349
, pp. 716-730
-
-
Becker, N.A.1
Kahn, J.D.2
Maher III, L.J.3
-
33
-
-
0023665196
-
Influence of supercoiling and sequence context on operator DNA binding with lac repressor
-
Whitson, P. A., Hsieh, W.-T., Wells, R. D. and Matthews, K. S. (1987) Influence of supercoiling and sequence context on operator DNA binding with lac repressor. J. Biol. Chem. 262, 14592-14599.
-
(1987)
J. Biol. Chem
, vol.262
, pp. 14592-14599
-
-
Whitson, P.A.1
Hsieh, W.-T.2
Wells, R.D.3
Matthews, K.S.4
-
34
-
-
0023665179
-
Influence of sequence and distance between two operators on interaction with the lac repressor
-
Hsieh, W.-T., Whitson, P. A., Matthews, K. S. and Wells, R. D. (1987) Influence of sequence and distance between two operators on interaction with the lac repressor. J. Biol. Chem. 262, 14583-14591.
-
(1987)
J. Biol. Chem
, vol.262
, pp. 14583-14591
-
-
Hsieh, W.-T.1
Whitson, P.A.2
Matthews, K.S.3
Wells, R.D.4
-
35
-
-
2142855754
-
DNA supercoiling changes the spacing requirement of two lac operators for DNA loop formation with lac repressor
-
Krämer, H., Amouyal, M., Nordheim, A. and Müller-Hill, B. (1988) DNA supercoiling changes the spacing requirement of two lac operators for DNA loop formation with lac repressor. EMBO J. 7, 547-556.
-
(1988)
EMBO J
, vol.7
, pp. 547-556
-
-
Krämer, H.1
Amouyal, M.2
Nordheim, A.3
Müller-Hill, B.4
-
36
-
-
0023333893
-
lac repressor forms loops with linear DNA carrying two suitably spaced lac operators
-
Krämer, H., Niemöller, M., Amouyal, M., Revet, B., von Wilcken-Bergmann, B. and Müller-Hill, B. (1987) lac repressor forms loops with linear DNA carrying two suitably spaced lac operators. EMBO J. 6, 1481-1491.
-
(1987)
EMBO J
, vol.6
, pp. 1481-1491
-
-
Krämer, H.1
Niemöller, M.2
Amouyal, M.3
Revet, B.4
von Wilcken-Bergmann, B.5
Müller-Hill, B.6
-
38
-
-
0025372285
-
lac repressor forms stable loops in vitro with supercoiled wild-type lac DNA containing all three natural lac operators
-
Eismann, E. R. and Müller-Hill, B. (1990) lac repressor forms stable loops in vitro with supercoiled wild-type lac DNA containing all three natural lac operators. J. Mol. Biol. 213, 763-765.
-
(1990)
J. Mol. Biol
, vol.213
, pp. 763-765
-
-
Eismann, E.R.1
Müller-Hill, B.2
-
39
-
-
0022884567
-
Base substitution mutants of the lac operator: In vivo and in vitro affinities for lac repressor
-
Betz, J. L., Sasmor, H. M., Buck, F., Insley, M. Y. and Caruthers, M. H. (1986) Base substitution mutants of the lac operator: in vivo and in vitro affinities for lac repressor. Gene 50, 123-132.
-
(1986)
Gene
, vol.50
, pp. 123-132
-
-
Betz, J.L.1
Sasmor, H.M.2
Buck, F.3
Insley, M.Y.4
Caruthers, M.H.5
-
40
-
-
0342687610
-
A perfectly symmetric lac operator binds the lac repressor very tightly
-
Sadler, J. R., Sasmor, H. and Betz, J. L. (1983) A perfectly symmetric lac operator binds the lac repressor very tightly. Proc. Natl. Acad. Sci. USA 80, 6785-6789.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 6785-6789
-
-
Sadler, J.R.1
Sasmor, H.2
Betz, J.L.3
-
41
-
-
0346569510
-
Possible ideal lac operator: Escherichia coli lac operator-like sequences from eukaryotic genomes lack the central G-C pair
-
Simons, A., Tils, D., von Wilcken-Bergmann, B. and Müller-Hill, B. (1984) Possible ideal lac operator: Escherichia coli lac operator-like sequences from eukaryotic genomes lack the central G-C pair. Proc. Natl. Acad. Sci. USA 81, 1624-1628.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 1624-1628
-
-
Simons, A.1
Tils, D.2
von Wilcken-Bergmann, B.3
Müller-Hill, B.4
-
42
-
-
0015918916
-
2-terminal region and loss of the deoxyribonucleic acid binding activity
-
2-terminal region and loss of the deoxyribonucleic acid binding activity. J. Biol. Chem. 248, 110-121.
-
(1973)
J. Biol. Chem
, vol.248
, pp. 110-121
-
-
Platt, T.1
Files, J.G.2
Weber, K.3
-
43
-
-
0018258345
-
An amino-terminal fragment of lac repressor binds specifically to lac operator
-
Ogata, R. T. and Gilbert, W. (1978) An amino-terminal fragment of lac repressor binds specifically to lac operator. Proc. Natl. Acad. Sci. USA 75, 5851-5854.
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, pp. 5851-5854
-
-
Ogata, R.T.1
Gilbert, W.2
-
44
-
-
0026723976
-
Deletion of lactose repressor carboxyl-terminal domain affects tetramer formation
-
Chen, J. and Matthews, K. S. (1992) Deletion of lactose repressor carboxyl-terminal domain affects tetramer formation. J. Biol. Chem. 267, 13843-13850.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 13843-13850
-
-
Chen, J.1
Matthews, K.S.2
-
45
-
-
0027297241
-
Genetic analysis of the leucine heptad repeats of Lac repressor: Evidence for a 4-helical bundle
-
Alberti, S., Oehler, S., von Wilcken-Bergmann, B. and Müller-Hill, B. (1993) Genetic analysis of the leucine heptad repeats of Lac repressor: evidence for a 4-helical bundle. EMBO J. 12, 3227-3236.
-
(1993)
EMBO J
, vol.12
, pp. 3227-3236
-
-
Alberti, S.1
Oehler, S.2
von Wilcken-Bergmann, B.3
Müller-Hill, B.4
-
46
-
-
78651189765
-
On the nature of allosteric transitions: A plausible model
-
Monod, J., Wyman, J. and Changeux, J. P. (1965) On the nature of allosteric transitions: a plausible model. J. Mol. Biol. 12, 88-118.
-
(1965)
J. Mol. Biol
, vol.12
, pp. 88-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.P.3
-
47
-
-
0013863816
-
Comparison of experimental binding data and theoretical models in proteins containing subunits
-
Koshland, D. E. Jr, Nemethy, G. and Filmer, D. (1966) Comparison of experimental binding data and theoretical models in proteins containing subunits. Biochemistry 5, 365-385.
-
(1966)
Biochemistry
, vol.5
, pp. 365-385
-
-
Koshland Jr, D.E.1
Nemethy, G.2
Filmer, D.3
-
48
-
-
32344434479
-
The changing landscape of protein allostery
-
Swain, J. F. and Gierasch, L. M. (2006) The changing landscape of protein allostery. Curr. Opin. Struct. Biol. 16, 102-108.
-
(2006)
Curr. Opin. Struct. Biol
, vol.16
, pp. 102-108
-
-
Swain, J.F.1
Gierasch, L.M.2
-
49
-
-
0346220393
-
The role of dynamics in allosteric regulation
-
Kern, D. and Zuiderweg, E. R. P. (2003) The role of dynamics in allosteric regulation. Curr. Opin. Struct. Biol. 13, 748-757.
-
(2003)
Curr. Opin. Struct. Biol
, vol.13
, pp. 748-757
-
-
Kern, D.1
Zuiderweg, E.R.P.2
-
50
-
-
6344219895
-
Is allostery an intrinsic property of all dynamic proteins?
-
Gunasekaran, K., Ma, B. and Nussinov, R. (2004) Is allostery an intrinsic property of all dynamic proteins? Proteins 57, 433-443.
-
(2004)
Proteins
, vol.57
, pp. 433-443
-
-
Gunasekaran, K.1
Ma, B.2
Nussinov, R.3
-
51
-
-
0023055763
-
Allosteric regulation of inducer and operator binding to the lactose repressor
-
Daly, T. J. and Matthews, K. S. (1986) Allosteric regulation of inducer and operator binding to the lactose repressor. Biochemistry 25, 5479-5484.
-
(1986)
Biochemistry
, vol.25
, pp. 5479-5484
-
-
Daly, T.J.1
Matthews, K.S.2
-
52
-
-
0019321794
-
Kinetic studies of inducer binding to lac repressor • operator complex
-
Dunaway, M., Olson, J. S., Rosenberg, J. M., Kallai, O. B., Dickerson, R. E. and Matthews, K. S. (1980) Kinetic studies of inducer binding to lac repressor • operator complex. J. Biol. Chem. 255, 10115-10119.
-
(1980)
J. Biol. Chem
, vol.255
, pp. 10115-10119
-
-
Dunaway, M.1
Olson, J.S.2
Rosenberg, J.M.3
Kallai, O.B.4
Dickerson, R.E.5
Matthews, K.S.6
-
53
-
-
0017330460
-
Interaction of lac repressor with inducer: Kinetic and equilibrium measurements
-
Friedman, B. E., Olson, J. S. and Matthews, K. S. (1977) Interaction of lac repressor with inducer: kinetic and equilibrium measurements. J. Mol. Biol. 111, 27-39.
-
(1977)
J. Mol. Biol
, vol.111
, pp. 27-39
-
-
Friedman, B.E.1
Olson, J.S.2
Matthews, K.S.3
-
54
-
-
0015526977
-
Equilibrium and kinetic studies of Escherichia coli lac repressor-inducer interactions
-
Laiken, S. L., Gross, C. A. and von Hippel, P. H. (1972) Equilibrium and kinetic studies of Escherichia coli lac repressor-inducer interactions. J. Mol. Biol. 66, 143-155.
-
(1972)
J. Mol. Biol
, vol.66
, pp. 143-155
-
-
Laiken, S.L.1
Gross, C.A.2
von Hippel, P.H.3
-
55
-
-
0015527087
-
Conformational change of the lac repressor induced with the inducer
-
Ohshima, Y., Matsuura, M. and Horiuchi, T. (1972) Conformational change of the lac repressor induced with the inducer. Biochem. Biophys. Res. Commun. 47, 1444-1450.
-
(1972)
Biochem. Biophys. Res. Commun
, vol.47
, pp. 1444-1450
-
-
Ohshima, Y.1
Matsuura, M.2
Horiuchi, T.3
-
56
-
-
0016251004
-
Ultraviolet difference spectra of the lactose repressor protein. II. Trypsin core protein
-
Matthews, K. S. (1974) Ultraviolet difference spectra of the lactose repressor protein. II. Trypsin core protein. Biochim. Biophys. Acta 359, 334-340.
-
(1974)
Biochim. Biophys. Acta
, vol.359
, pp. 334-340
-
-
Matthews, K.S.1
-
57
-
-
0017376038
-
Fluorescence and ultraviolet spectral studies of lac repressor modified with N-bromosuccinimide
-
O'Gorman, R. B. and Matthews, K. S. (1977) Fluorescence and ultraviolet spectral studies of lac repressor modified with N-bromosuccinimide. J. Biol. Chem. 252, 3572-3577.
-
(1977)
J. Biol. Chem
, vol.252
, pp. 3572-3577
-
-
O'Gorman, R.B.1
Matthews, K.S.2
-
58
-
-
0025237781
-
lac repressor: Crystallization of intact tetramer and its complexes with inducer and operator DNA
-
Pace, H. C., Lu, P. and Lewis, M. (1990) lac repressor: crystallization of intact tetramer and its complexes with inducer and operator DNA. Proc. Natl. Acad. Sci. USA 87, 1870-1873.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 1870-1873
-
-
Pace, H.C.1
Lu, P.2
Lewis, M.3
-
59
-
-
0022419169
-
A protein structure from nuclear magnetic resonance data: Lac repressor headpiece
-
Kaptein, R., Zuiderweg, E. R. P., Scheck, R. M., Boelens, R. and van Gunsteren, W. F. (1985) A protein structure from nuclear magnetic resonance data: lac repressor headpiece. J. Mol. Biol. 182, 179-182.
-
(1985)
J. Mol. Biol
, vol.182
, pp. 179-182
-
-
Kaptein, R.1
Zuiderweg, E.R.P.2
Scheck, R.M.3
Boelens, R.4
van Gunsteren, W.F.5
-
60
-
-
0029004903
-
Crystal structure of lac repressor core tetramer and its implications for DNA looping
-
Friedman, A. M., Fischmann, T. O. and Steitz, T. A. (1995) Crystal structure of lac repressor core tetramer and its implications for DNA looping. Science 268, 1721-1727.
-
(1995)
Science
, vol.268
, pp. 1721-1727
-
-
Friedman, A.M.1
Fischmann, T.O.2
Steitz, T.A.3
-
61
-
-
0029938053
-
Crystal structure of the lactose operon repressor and its complexes with DNA and inducer
-
Lewis, M., Chang, G., Horton, N. C., Kercher, M. A., Pace, H. C., Schumacher, M. A., Brennan, R. G. and Lu, P. (1996) Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Science 271, 1247-1254.
-
(1996)
Science
, vol.271
, pp. 1247-1254
-
-
Lewis, M.1
Chang, G.2
Horton, N.C.3
Kercher, M.A.4
Pace, H.C.5
Schumacher, M.A.6
Brennan, R.G.7
Lu, P.8
-
62
-
-
0034089394
-
A closer view of the conformation of the Lac repressor bound to operator
-
Bell, C. E. and Lewis, M. (2000) A closer view of the conformation of the Lac repressor bound to operator. Nat. Struct. Biol. 7, 209-214.
-
(2000)
Nat. Struct. Biol
, vol.7
, pp. 209-214
-
-
Bell, C.E.1
Lewis, M.2
-
63
-
-
0035812627
-
Crystallographic analysis of Lac repressor bound to natural operator O1
-
Bell, C. E. and Lewis, M. (2001) Crystallographic analysis of Lac repressor bound to natural operator O1. J. Mol. Biol. 312, 921-926.
-
(2001)
J. Mol. Biol
, vol.312
, pp. 921-926
-
-
Bell, C.E.1
Lewis, M.2
-
64
-
-
0035850794
-
Structure of a variant of lac repressor with increased thermostability and decreased affinity for operator
-
Bell, C. E., Barry, J., Matthews, K. S. and Lewis, M. (2001) Structure of a variant of lac repressor with increased thermostability and decreased affinity for operator. J. Mol. Biol. 313, 99-109.
-
(2001)
J. Mol. Biol
, vol.313
, pp. 99-109
-
-
Bell, C.E.1
Barry, J.2
Matthews, K.S.3
Lewis, M.4
-
65
-
-
0030596509
-
Refined structure of lac repressor headpiece (1-56) determined by relaxation matrix calculations from 2D and 3D NOE data: Change of tertiary structure upon binding to the lac operator
-
Slijper, M., Bonvin, A. M. J. J., Boelens, R. and Kaptein, R. (1996) Refined structure of lac repressor headpiece (1-56) determined by relaxation matrix calculations from 2D and 3D NOE data: change of tertiary structure upon binding to the lac operator. J. Mol. Biol. 259, 761-773.
-
(1996)
J. Mol. Biol
, vol.259
, pp. 761-773
-
-
Slijper, M.1
Bonvin, A.M.J.J.2
Boelens, R.3
Kaptein, R.4
-
66
-
-
0018800357
-
Differential mobility of the N-terminal headpiece in the lac-repressor protein
-
Wade-Jardetzky, N., Bray, R. P., Conover, W. W., Jardetzky, O., Geisler, N. and Weber, K. (1979) Differential mobility of the N-terminal headpiece in the lac-repressor protein. J. Mol. Biol. 128, 259-264.
-
(1979)
J. Mol. Biol
, vol.128
, pp. 259-264
-
-
Wade-Jardetzky, N.1
Bray, R.P.2
Conover, W.W.3
Jardetzky, O.4
Geisler, N.5
Weber, K.6
-
67
-
-
0029976830
-
Formation of the hinge helix in the lac repressor is induced upon binding to the lac operator
-
Spronk, C. A. E. M., Slijper, M., van Boom, J. H., Kaptein, R. and Boelens, R. (1996) Formation of the hinge helix in the lac repressor is induced upon binding to the lac operator. Nat. Struct. Biol. 3, 916-919.
-
(1996)
Nat. Struct. Biol
, vol.3
, pp. 916-919
-
-
Spronk, C.A.E.M.1
Slijper, M.2
van Boom, J.H.3
Kaptein, R.4
Boelens, R.5
-
68
-
-
0036182617
-
A residue-specific view of the association and dissociation pathway in protein-DNA recognition
-
Kalodimos, C. G., Boelens, R. and Kaptein, R. (2002) A residue-specific view of the association and dissociation pathway in protein-DNA recognition. Nat. Struct. Biol. 9, 193-197.
-
(2002)
Nat. Struct. Biol
, vol.9
, pp. 193-197
-
-
Kalodimos, C.G.1
Boelens, R.2
Kaptein, R.3
-
69
-
-
3142657230
-
Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes
-
Kalodimos, C. G., Biris, N., Bonvin, A. M. J. J., Levandoski, M. M., Guennuegues, M., Boelens, R. and Kaptein, R. (2004) Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes. Science 305, 386-389.
-
(2004)
Science
, vol.305
, pp. 386-389
-
-
Kalodimos, C.G.1
Biris, N.2
Bonvin, A.M.J.J.3
Levandoski, M.M.4
Guennuegues, M.5
Boelens, R.6
Kaptein, R.7
-
70
-
-
0036127292
-
Fine-tuning function: Correlation of hinge domain interactions with functional distinctions between LacI and PurR
-
Swint-Kruse, L., Larson, C., Pettitt, B. M. and Matthews, K. S. (2002) Fine-tuning function: correlation of hinge domain interactions with functional distinctions between LacI and PurR. Protein Sci. 11, 778-794.
-
(2002)
Protein Sci
, vol.11
, pp. 778-794
-
-
Swint-Kruse, L.1
Larson, C.2
Pettitt, B.M.3
Matthews, K.S.4
-
71
-
-
0027256676
-
Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria
-
Tam, R. and Saier, M. H. Jr (1993) Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria. Microbiol. Rev. 57, 320-346.
-
(1993)
Microbiol. Rev
, vol.57
, pp. 320-346
-
-
Tam, R.1
Saier Jr, M.H.2
-
72
-
-
33544461370
-
The Venus flytrap of periplasmic binding proteins: An ancient protein module present in multiple drug receptors
-
Felder, C. B., Graul, R. C., Lee, A. Y., Merkle, H. P. and Sadee, W. (1999) The Venus flytrap of periplasmic binding proteins: an ancient protein module present in multiple drug receptors. AAPS PharmSci. 1: E2.
-
(1999)
AAPS PharmSci
, vol.1
-
-
Felder, C.B.1
Graul, R.C.2
Lee, A.Y.3
Merkle, H.P.4
Sadee, W.5
-
73
-
-
0028059578
-
Subunit dissociation affects DNA binding in a dimeric lac repressor produced by C-terminal deletion
-
Chen, J. and Matthews, K. S. (1994) Subunit dissociation affects DNA binding in a dimeric lac repressor produced by C-terminal deletion. Biochemistry 33, 8728-8735.
-
(1994)
Biochemistry
, vol.33
, pp. 8728-8735
-
-
Chen, J.1
Matthews, K.S.2
-
74
-
-
0028334191
-
Wild-type operator binding and altered cooperativity for inducer binding of lac repressor dimer mutant R3
-
Chen, J., Alberti, S. and Matthews, K. S. (1994) Wild-type operator binding and altered cooperativity for inducer binding of lac repressor dimer mutant R3. J. Biol. Chem. 269, 12482-12487.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 12482-12487
-
-
Chen, J.1
Alberti, S.2
Matthews, K.S.3
-
75
-
-
0142179045
-
Allosteric transition pathways in the lactose repressor protein core domains: Asymmetric motions in a homodimer
-
Flynn, T. C., Swint-Kruse, L., Kong, Y., Booth, C., Matthews, K. S. and Ma, J. (2003) Allosteric transition pathways in the lactose repressor protein core domains: asymmetric motions in a homodimer. Protein Sci. 12, 2523-2541.
-
(2003)
Protein Sci
, vol.12
, pp. 2523-2541
-
-
Flynn, T.C.1
Swint-Kruse, L.2
Kong, Y.3
Booth, C.4
Matthews, K.S.5
Ma, J.6
-
76
-
-
0035108019
-
Plasticity of quaternary structure: Twenty-two ways to form a LacI dimer
-
Swint-Kruse, L., Elam, C. R., Lin, J. W., Wycuff, D. R. and Matthews, K. S. (2001) Plasticity of quaternary structure: twenty-two ways to form a LacI dimer. Protein Sci. 10, 262-276.
-
(2001)
Protein Sci
, vol.10
, pp. 262-276
-
-
Swint-Kruse, L.1
Elam, C.R.2
Lin, J.W.3
Wycuff, D.R.4
Matthews, K.S.5
-
77
-
-
4644290827
-
Using networks to identify fine structural differences between functionally distinct protein states
-
Swint-Kruse, L. (2004) Using networks to identify fine structural differences between functionally distinct protein states. Biochemistry 43, 10886-10895.
-
(2004)
Biochemistry
, vol.43
, pp. 10886-10895
-
-
Swint-Kruse, L.1
-
78
-
-
18744391399
-
Structural dynamics of the lac repressor-DNA complex revealed by a multiscale simulation
-
Villa, E., Balaeff, A. and Schulten, K. (2005) Structural dynamics of the lac repressor-DNA complex revealed by a multiscale simulation. Proc. Natl. Acad. Sci. USA 102, 6783-6788.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 6783-6788
-
-
Villa, E.1
Balaeff, A.2
Schulten, K.3
-
79
-
-
33745595880
-
Modeling the Lac repressor-operator assembly: The influence of DNA looping on Lac repressor conformation
-
Swigon, D., Coleman, B. D. and Olson, W. K. (2006) Modeling the Lac repressor-operator assembly: the influence of DNA looping on Lac repressor conformation. Proc. Natl. Acad. Sci. USA 103, 9879-9884.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 9879-9884
-
-
Swigon, D.1
Coleman, B.D.2
Olson, W.K.3
-
80
-
-
0021771027
-
Genetic studies of lac repressor. XII. Amino acid replacements in the DNA binding domain of the Escherichia coli lac repressor
-
Miller, J. H. (1984) Genetic studies of lac repressor. XII. Amino acid replacements in the DNA binding domain of the Escherichia coli lac repressor. J. Mol. Biol. 180, 205-212.
-
(1984)
J. Mol. Biol
, vol.180
, pp. 205-212
-
-
Miller, J.H.1
-
81
-
-
0028076771
-
Genetic studies of the lac repressor. XIV. Analysis of 4000 altered Escherichia coli lac repressors reveals essential and non-essential residues, as well as 'spacers' which do not require a specific sequence
-
Markiewicz, P., Kleina, L. G., Cruz, C., Ehret, S. and Miller, J. H. (1994) Genetic studies of the lac repressor. XIV. Analysis of 4000 altered Escherichia coli lac repressors reveals essential and non-essential residues, as well as 'spacers' which do not require a specific sequence. J. Mol. Biol. 240, 421-433.
-
(1994)
J. Mol. Biol
, vol.240
, pp. 421-433
-
-
Markiewicz, P.1
Kleina, L.G.2
Cruz, C.3
Ehret, S.4
Miller, J.H.5
-
82
-
-
2342519701
-
Genetic studies of the Lac repressor. XV: 4000 single amino acid substitutions and analysis of the resulting phenotypes on the basis of the protein structure
-
Suckow, J., Markiewicz, P., Kleina, L. G., Miller, J., Kisters-Woike, B. and Müller-Hill, B. (1996) Genetic studies of the Lac repressor. XV: 4000 single amino acid substitutions and analysis of the resulting phenotypes on the basis of the protein structure. J. Mol. Biol. 261, 509-523.
-
(1996)
J. Mol. Biol
, vol.261
, pp. 509-523
-
-
Suckow, J.1
Markiewicz, P.2
Kleina, L.G.3
Miller, J.4
Kisters-Woike, B.5
Müller-Hill, B.6
-
83
-
-
0024292398
-
Missense mutation in the lacI gene of Escherichia coli: Inferences on the structure of the repressor protein
-
Gordon, A. J. E., Burns, P. A., Fix, D. F., Yatagai, F., Allen, F. L., Horsfall, M. J., Halliday, J. A., Gray, J., Bernelot-Moens, C. and Glickman, B. W. (1988) Missense mutation in the lacI gene of Escherichia coli: inferences on the structure of the repressor protein. J. Mol. Biol. 200, 239-251.
-
(1988)
J. Mol. Biol
, vol.200
, pp. 239-251
-
-
Gordon, A.J.E.1
Burns, P.A.2
Fix, D.F.3
Yatagai, F.4
Allen, F.L.5
Horsfall, M.J.6
Halliday, J.A.7
Gray, J.8
Bernelot-Moens, C.9
Glickman, B.W.10
-
84
-
-
0024988263
-
Resolution of the fluorescence decay of the two tryptophan residues of lac repressor using single tryptophan mutants
-
Royer, C. A., Gardner, J. A., Beechem, J. M., Brochon J.-C. and Matthews, K. S. (1990) Resolution of the fluorescence decay of the two tryptophan residues of lac repressor using single tryptophan mutants. Biophys. J. 58, 363-378.
-
(1990)
Biophys. J
, vol.58
, pp. 363-378
-
-
Royer, C.A.1
Gardner, J.A.2
Beechem, J.M.3
Brochon, J.-C.4
Matthews, K.S.5
-
85
-
-
0022144357
-
Photochemical modifications of lac repressor: Effect of effectors binding on tryptophan photooxidation
-
Spodheim-Maurizot, M., Charlier, M. and Helene, C. (1985) Photochemical modifications of lac repressor: effect of effectors binding on tryptophan photooxidation. Photochem. Photobiol. 42, 353-359.
-
(1985)
Photochem. Photobiol
, vol.42
, pp. 353-359
-
-
Spodheim-Maurizot, M.1
Charlier, M.2
Helene, C.3
-
86
-
-
23944464891
-
Integrated insights from simulation, experiment, and mutational analysis yield new details of LacI function
-
Swint-Kruse, L., Zhan, H. and Matthews, K. S. (2005) Integrated insights from simulation, experiment, and mutational analysis yield new details of LacI function. Biochemistry 44, 11201-11213.
-
(2005)
Biochemistry
, vol.44
, pp. 11201-11213
-
-
Swint-Kruse, L.1
Zhan, H.2
Matthews, K.S.3
-
87
-
-
0027236781
-
Lysine 84 is at the subunit interface of lac repressor protein
-
Chang W.-I., Olson, J. S. and Matthews, K. S. (1993) Lysine 84 is at the subunit interface of lac repressor protein. J. Biol. Chem. 268, 17613-17622.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 17613-17622
-
-
Chang, W.-I.1
Olson, J.S.2
Matthews, K.S.3
-
88
-
-
0017781040
-
High resolution 1H NMR of a selectively deuterated analog of the lac repressor
-
Matthews, K. S., Wade-Jardetzky, N. G., Graber, M., Conover, W. W. and Jardetzky, O. (1977) High resolution 1H NMR of a selectively deuterated analog of the lac repressor. Biochim. Biophys. Acta 490, 534-538.
-
(1977)
Biochim. Biophys. Acta
, vol.490
, pp. 534-538
-
-
Matthews, K.S.1
Wade-Jardetzky, N.G.2
Graber, M.3
Conover, W.W.4
Jardetzky, O.5
-
89
-
-
0019569785
-
Genetic assignment of resonances in the NMR spectrum of a protein: Lac repressor
-
Jarema, M. A. C., Lu, P. and Miller, J. H. (1981) Genetic assignment of resonances in the NMR spectrum of a protein: lac repressor. Proc. Natl. Acad. Sci. USA 78, 2707-2711.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 2707-2711
-
-
Jarema, M.A.C.1
Lu, P.2
Miller, J.H.3
-
90
-
-
1542269057
-
Thermodynamics, protein modification, and molecular dynamics in characterizing lactose repressor protein: Strategies for complex analyses of protein structure-function
-
Swint-Kruse, L. and Matthews, K. S. (2004) Thermodynamics, protein modification, and molecular dynamics in characterizing lactose repressor protein: strategies for complex analyses of protein structure-function. Methods Enzymol. 379, 188-209.
-
(2004)
Methods Enzymol
, vol.379
, pp. 188-209
-
-
Swint-Kruse, L.1
Matthews, K.S.2
-
91
-
-
0344412958
-
Perturbation from a distance: Mutations that alter LacI function through long-range effects
-
Swint-Kruse, L., Zhan, H., Fairbanks, B. M., Maheshwari, A. and Matthews, K. S. (2003) Perturbation from a distance: mutations that alter LacI function through long-range effects. Biochemistry 42, 14004-14016.
-
(2003)
Biochemistry
, vol.42
, pp. 14004-14016
-
-
Swint-Kruse, L.1
Zhan, H.2
Fairbanks, B.M.3
Maheshwari, A.4
Matthews, K.S.5
-
92
-
-
0033596862
-
Substitutions at histidine 74 and aspartate 278 alter ligand binding and allostery in lactose repressor protein
-
Barry, J. K. and Matthews, K. S. (1999) Substitutions at histidine 74 and aspartate 278 alter ligand binding and allostery in lactose repressor protein. Biochemistry 38, 3579-3590.
-
(1999)
Biochemistry
, vol.38
, pp. 3579-3590
-
-
Barry, J.K.1
Matthews, K.S.2
-
93
-
-
0031982791
-
Comparison of simulated and experimentally determined dynamics for a variant of the LacI DNA binding domain, Nlac-P
-
Swint-Kruse, L., Matthews, K. S., Smith, P. E. and Pettitt, B. M. (1998) Comparison of simulated and experimentally determined dynamics for a variant of the LacI DNA binding domain, Nlac-P. Biophys. J. 74, 413-421.
-
(1998)
Biophys. J
, vol.74
, pp. 413-421
-
-
Swint-Kruse, L.1
Matthews, K.S.2
Smith, P.E.3
Pettitt, B.M.4
-
94
-
-
4344581629
-
Toward an integrated model of protein-DNA recognition as inferred from NMR studies on the lac repressor system
-
Kalodimos, C. G., Boelens, R. and Kaptein, R. (2004) Toward an integrated model of protein-DNA recognition as inferred from NMR studies on the lac repressor system. Chem. Rev. 104, 3567-3586.
-
(2004)
Chem. Rev
, vol.104
, pp. 3567-3586
-
-
Kalodimos, C.G.1
Boelens, R.2
Kaptein, R.3
-
95
-
-
0037124326
-
Plasticity in protein-DNA recognition: Lac repressor interacts with its natural operator O1 through alternative conformations of its DNA binding domain
-
Kalodimos, C. G., Bonvin, A. M. J. J., Salinas, R. K., Wechselberger, R., Boelens, R. and Kaptein, R. (2002) Plasticity in protein-DNA recognition: lac repressor interacts with its natural operator O1 through alternative conformations of its DNA binding domain. EMBO 121, 2866-2876.
-
(2002)
EMBO
, vol.121
, pp. 2866-2876
-
-
Kalodimos, C.G.1
Bonvin, A.M.J.J.2
Salinas, R.K.3
Wechselberger, R.4
Boelens, R.5
Kaptein, R.6
-
96
-
-
0035933104
-
Strong DNA binding by covalently linked dimeric Lac headpiece: Evidence for the crucial role of the hinge helices
-
Kalodimos, C. G., Folkers, G. E., Boelens, R. and Kaptein, R. (2001) Strong DNA binding by covalently linked dimeric Lac headpiece: evidence for the crucial role of the hinge helices. Proc. Natl. Acad. Sci. USA 98, 6039-6044.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6039-6044
-
-
Kalodimos, C.G.1
Folkers, G.E.2
Boelens, R.3
Kaptein, R.4
-
97
-
-
0030774567
-
Designed disulfide between N-terminal domains of lactose repressor disrupts allosteric linkage
-
Falcon, C. M., Swint-Kruse, L. and Matthews, K. S. (1997) Designed disulfide between N-terminal domains of lactose repressor disrupts allosteric linkage. J. Biol. Chem. 272, 26818-26821.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 26818-26821
-
-
Falcon, C.M.1
Swint-Kruse, L.2
Matthews, K.S.3
-
98
-
-
0035951105
-
Engineered disulfide linking the hinge regions within lactose repressor dimer increases operator affinity, decreases sequence selectivity, and alters allostery
-
Falcon, C. M. and Matthews, K. S. (2001) Engineered disulfide linking the hinge regions within lactose repressor dimer increases operator affinity, decreases sequence selectivity, and alters allostery. Biochemistry 40, 15650-15659.
-
(2001)
Biochemistry
, vol.40
, pp. 15650-15659
-
-
Falcon, C.M.1
Matthews, K.S.2
-
99
-
-
0032718889
-
Glycine insertion in the hinge region of lactose repressor protein alters DNA binding
-
Falcon, C. M. and Matthews, K. S. (1999) Glycine insertion in the hinge region of lactose repressor protein alters DNA binding. J. Biol. Chem. 274, 30849-30857.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 30849-30857
-
-
Falcon, C.M.1
Matthews, K.S.2
-
100
-
-
0034641681
-
Operator DNA sequence variation enhances high affinity binding by hinge helix mutants of lactose repressor protein
-
Falcon, C. M. and Matthews, K. S. (2000) Operator DNA sequence variation enhances high affinity binding by hinge helix mutants of lactose repressor protein. Biochemistry 39, 11074-11083.
-
(2000)
Biochemistry
, vol.39
, pp. 11074-11083
-
-
Falcon, C.M.1
Matthews, K.S.2
-
101
-
-
33646472260
-
Extrinsic interactions dominate helical propensity in coupled binding and folding of the lactose repressor protein hinge helix
-
Zhan, H., Swint-Kruse, L. and Matthews, K. S. (2006) Extrinsic interactions dominate helical propensity in coupled binding and folding of the lactose repressor protein hinge helix. Biochemistry 45, 5896-5906.
-
(2006)
Biochemistry
, vol.45
, pp. 5896-5906
-
-
Zhan, H.1
Swint-Kruse, L.2
Matthews, K.S.3
-
102
-
-
3943113660
-
Using protein folding rates to test protein folding theories
-
Gillespie, B. and Plaxco, B. W. (2004) Using protein folding rates to test protein folding theories. Annu. Rev. Biochem. 73, 837-859.
-
(2004)
Annu. Rev. Biochem
, vol.73
, pp. 837-859
-
-
Gillespie, B.1
Plaxco, B.W.2
-
103
-
-
0027313673
-
Pathways of protein folding
-
Matthews, C. R. (1993) Pathways of protein folding. Annu. Rev. Biochem. 62, 653-683.
-
(1993)
Annu. Rev. Biochem
, vol.62
, pp. 653-683
-
-
Matthews, C.R.1
-
104
-
-
0031932170
-
Favorable domain size in proteins
-
Xu, D. and Nussinov, R. (1997) Favorable domain size in proteins. Fold. Design 3, 11-17.
-
(1997)
Fold. Design
, vol.3
, pp. 11-17
-
-
Xu, D.1
Nussinov, R.2
-
105
-
-
26844543506
-
Characterization of the folding landscape of monomeric lactose repressor: Quantitative comparison of theory and experiment
-
Das, P., Wilson, C. J., Fossati, G., Wittung-Stafshede, P., Matthews, K. S. and Clementi, C. (2005) Characterization of the folding landscape of monomeric lactose repressor: Quantitative comparison of theory and experiment. Proc. Natl. Acad. Sci. USA 102, 14569-14574.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 14569-14574
-
-
Das, P.1
Wilson, C.J.2
Fossati, G.3
Wittung-Stafshede, P.4
Matthews, K.S.5
Clementi, C.6
-
106
-
-
26844536032
-
The experimental folding landscape of monomeric lactose repressor, a large two-domain protein, involves two kinetic intermediates
-
Wilson, C. J., Das, P., Clementi, C., Matthews, K. S. and Wittung-Stafshede, P. (2005) The experimental folding landscape of monomeric lactose repressor, a large two-domain protein, involves two kinetic intermediates. Proc. Natl. Acad. Sci. USA 102, 14563-14568.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 14563-14568
-
-
Wilson, C.J.1
Das, P.2
Clementi, C.3
Matthews, K.S.4
Wittung-Stafshede, P.5
-
107
-
-
0033580635
-
Thermodynamic analysis of unfolding and dissociation in lactose repressor protein
-
Barry, J. K. and Matthews, K. S. (1999) Thermodynamic analysis of unfolding and dissociation in lactose repressor protein. Biochemistry 38, 6520-6528.
-
(1999)
Biochemistry
, vol.38
, pp. 6520-6528
-
-
Barry, J.K.1
Matthews, K.S.2
-
108
-
-
0030806865
-
Combinatorial mutations of lac repressor. Stability of monomer-monomer interface is increased by apolar substitution at position 84
-
Nichols, J. C. and Matthews, K. S. (1997) Combinatorial mutations of lac repressor. Stability of monomer-monomer interface is increased by apolar substitution at position 84. J. Biol. Chem. 272, 18550-18557.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 18550-18557
-
-
Nichols, J.C.1
Matthews, K.S.2
-
109
-
-
0032780907
-
Dimerisation mutants of Lac repressor. I. A monomeric mutant, L251A, that binds lac operator DNA as a dimer
-
Dong, F., Spott, S., Zimmermann, O., Kisters-Woike, B., Müller-Hill, B. and Barker, A. (1999) Dimerisation mutants of Lac repressor. I. A monomeric mutant, L251A, that binds lac operator DNA as a dimer. J. Mol. Biol. 290, 653-666.
-
(1999)
J. Mol. Biol
, vol.290
, pp. 653-666
-
-
Dong, F.1
Spott, S.2
Zimmermann, O.3
Kisters-Woike, B.4
Müller-Hill, B.5
Barker, A.6
-
110
-
-
0020972782
-
Theoretical studies of protein folding
-
Go, N. (1983) Theoretical studies of protein folding. Annu. Rev. Biophys. Bioeng. 12, 183-210.
-
(1983)
Annu. Rev. Biophys. Bioeng
, vol.12
, pp. 183-210
-
-
Go, N.1
-
111
-
-
0026724966
-
A family of bacterial regulators homologous to Gal and Lac repressors
-
Weickert, M. J. and Adhya, S. (1992) A family of bacterial regulators homologous to Gal and Lac repressors. J. Biol. Chem. 267, 15869-15874.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 15869-15874
-
-
Weickert, M.J.1
Adhya, S.2
-
112
-
-
0345102549
-
Conformational changes of ribose-binding protein and two related repressors are tailored to fit the functional need
-
Mowbray, S. L. and Björkman, A. J. (1999) Conformational changes of ribose-binding protein and two related repressors are tailored to fit the functional need. J. Mol. Biol. 294, 487-499.
-
(1999)
J. Mol. Biol
, vol.294
, pp. 487-499
-
-
Mowbray, S.L.1
Björkman, A.J.2
-
113
-
-
0032054156
-
Protein engineering and the development of genetic biosensors
-
Hellinga, H. W. and Marvin, J. S. (1998) Protein engineering and the development of genetic biosensors. Trends Biotechnol. 16, 183-189.
-
(1998)
Trends Biotechnol
, vol.16
, pp. 183-189
-
-
Hellinga, H.W.1
Marvin, J.S.2
-
114
-
-
0035942160
-
Conversion of a maltose receptor into a zinc biosensor by computational design
-
Marvin, J. S. and Hellinga, H. W. (2001) Conversion of a maltose receptor into a zinc biosensor by computational design. Proc. Natl. Acad. Sci. USA 98, 4955-4960.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4955-4960
-
-
Marvin, J.S.1
Hellinga, H.W.2
-
115
-
-
0036525714
-
De novo design of biocatalysts
-
Bolon, D. N., Voigt, C. A. and Mayo, S. L. (2002) De novo design of biocatalysts. Curr. Opin. Chem. Biol. 6, 125-129.
-
(2002)
Curr. Opin. Chem. Biol
, vol.6
, pp. 125-129
-
-
Bolon, D.N.1
Voigt, C.A.2
Mayo, S.L.3
-
116
-
-
4143115810
-
Periplasmic binding proteins: A versatile superfamily for protein engineering
-
Dwyer, M. A. and Hellinga, H. W. (2004) Periplasmic binding proteins: a versatile superfamily for protein engineering. Curr. Opin. Struct. Biol. 14, 495-504.
-
(2004)
Curr. Opin. Struct. Biol
, vol.14
, pp. 495-504
-
-
Dwyer, M.A.1
Hellinga, H.W.2
-
117
-
-
0028115617
-
Transmembrane signalling by a hybrid protein: Communication from the domain of chemoreceptor Trg that recognizes sugar-binding proteins to the kinase/phosphatase domain of osmosensor EnvZ
-
Baumgartner, J. W., Kim, C., Brissette, R. E., Inouye, M., Park, C. and Hazelbauer, G. L. (1994) Transmembrane signalling by a hybrid protein: communication from the domain of chemoreceptor Trg that recognizes sugar-binding proteins to the kinase/phosphatase domain of osmosensor EnvZ. J. Bacteriol. 176, 1157-1163.
-
(1994)
J. Bacteriol
, vol.176
, pp. 1157-1163
-
-
Baumgartner, J.W.1
Kim, C.2
Brissette, R.E.3
Inouye, M.4
Park, C.5
Hazelbauer, G.L.6
-
118
-
-
0017123034
-
Mutations affecting the quaternary structure of the lac repressor
-
Schmitz, A., Schmeissner, U., Miller, J. H. and Lu, P. (1976) Mutations affecting the quaternary structure of the lac repressor. J. Biol. Chem. 251, 3359-3366.
-
(1976)
J. Biol. Chem
, vol.251
, pp. 3359-3366
-
-
Schmitz, A.1
Schmeissner, U.2
Miller, J.H.3
Lu, P.4
-
119
-
-
0026560373
-
-
Chen, J. and Matthews, K. S. (1992) T41 mutation in lac repressor is Tyr282 to Asp. Gene 111, 145-146.
-
Chen, J. and Matthews, K. S. (1992) T41 mutation in lac repressor is Tyr282 to Asp. Gene 111, 145-146.
-
-
-
-
120
-
-
0023055776
-
Characterization and modification of a monomeric mutant of the lactose repressor protein
-
Daly, T. J. and Matthews, K. S. (1986) Characterization and modification of a monomeric mutant of the lactose repressor protein. Biochemistry 25, 5474-5478.
-
(1986)
Biochemistry
, vol.25
, pp. 5474-5478
-
-
Daly, T.J.1
Matthews, K.S.2
-
121
-
-
0023449962
-
Spin glasses and the statistical mechanics of protein folding
-
Bryngelson, J. D. and Wolynes, P. G. (1987) Spin glasses and the statistical mechanics of protein folding. Proc. Natl. Acad. Sci. USA 84, 7524-7528.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 7524-7528
-
-
Bryngelson, J.D.1
Wolynes, P.G.2
-
122
-
-
33846469633
-
Functional consequences of domain swapping between the LacI/GalR transcription regulatory proteins
-
Swint-Kruse, L., Zhan, H., Meinhardt, S. and Tungtur, S. (2006) Functional consequences of domain swapping between the LacI/GalR transcription regulatory proteins. Biophys. J. 90, 346A.
-
(2006)
Biophys. J
, vol.90
-
-
Swint-Kruse, L.1
Zhan, H.2
Meinhardt, S.3
Tungtur, S.4
-
123
-
-
4444256116
-
Regulatory circuit design and evolution using phage lambda
-
Atsumi, S. and Little, J. W. (2004) Regulatory circuit design and evolution using phage lambda. Genes Dev. 18, 2086-2094.
-
(2004)
Genes Dev
, vol.18
, pp. 2086-2094
-
-
Atsumi, S.1
Little, J.W.2
-
124
-
-
0023666091
-
The inducible lac operator-repressor system is functional in mammalian cells
-
Hu, M. C.-T. and Davidson, N. (1987) The inducible lac operator-repressor system is functional in mammalian cells. Cell 48, 555-566.
-
(1987)
Cell
, vol.48
, pp. 555-566
-
-
Hu, M.C.-T.1
Davidson, N.2
-
125
-
-
0026535293
-
Modifications of the E. coli Lac repressor for expression in eukaryotic cells: Effects of nuclear signal sequences on protein activity and nuclear accumulation
-
Fieck, A., Wyborski, D. L. and Short, J. M. (1992) Modifications of the E. coli Lac repressor for expression in eukaryotic cells: effects of nuclear signal sequences on protein activity and nuclear accumulation. Nucleic Acids Res. 20, 1785-1791.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 1785-1791
-
-
Fieck, A.1
Wyborski, D.L.2
Short, J.M.3
-
126
-
-
0035876445
-
The lac operator-repressor system is functional in the mouse
-
Cronin, C. A., Gluba, W. and Scrable, H. (2001) The lac operator-repressor system is functional in the mouse. Genes Dev. 15, 1506-1517.
-
(2001)
Genes Dev
, vol.15
, pp. 1506-1517
-
-
Cronin, C.A.1
Gluba, W.2
Scrable, H.3
-
127
-
-
20444415980
-
Immobilisation of a repressor protein for binding of plasmid DNA
-
Hasche, A. and Voss, C. (2005) Immobilisation of a repressor protein for binding of plasmid DNA. J. Chromtogr. A 1080, 76-82.
-
(2005)
J. Chromtogr. A
, vol.1080
, pp. 76-82
-
-
Hasche, A.1
Voss, C.2
-
128
-
-
0027104361
-
Interlocking of plasmid DNAs due to lac repressor-operator interaction
-
Wu H.-Y., Lau, K. and Liu, L. F. (1992) Interlocking of plasmid DNAs due to lac repressor-operator interaction. J. Mol. Biol. 228, 1104-1114.
-
(1992)
J. Mol. Biol
, vol.228
, pp. 1104-1114
-
-
Wu, H.-Y.1
Lau, K.2
Liu, L.F.3
-
129
-
-
13444257509
-
Chromosome looping in yeast: Telomere pairing and coordinated movement reflect anchoring efficiency and territorial organization
-
Bystricky, K., Laroche, T., van Houwe, G., Blaszczyk, M. and Gasser, S. M. (2005) Chromosome looping in yeast: telomere pairing and coordinated movement reflect anchoring efficiency and territorial organization. J. Cell Biol. 168, 375-387.
-
(2005)
J. Cell Biol
, vol.168
, pp. 375-387
-
-
Bystricky, K.1
Laroche, T.2
van Houwe, G.3
Blaszczyk, M.4
Gasser, S.M.5
-
130
-
-
3042545272
-
Conditional gene silencing utilizing the lac repressor reveals a role of SHP-2 in cagA-positive Helicobacter pylori pathogenicity
-
Higuchi, M., Tsutsumi, R., Higashi, H. and Hatakeyama, M. (2004) Conditional gene silencing utilizing the lac repressor reveals a role of SHP-2 in cagA-positive Helicobacter pylori pathogenicity. Cancer Sci. 95, 442-447.
-
(2004)
Cancer Sci
, vol.95
, pp. 442-447
-
-
Higuchi, M.1
Tsutsumi, R.2
Higashi, H.3
Hatakeyama, M.4
|