Substitutions at histidine 74 and aspartate 278 alter ligand binding and allostery in lactose repressor protein

Biochemistry

Volumn 38, Issue 12, 1999, Pages 3579-3590

  Barry, Jennifer K ^a   Matthews, Kathleen S ^a  

^a RICE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; DNA; HISTIDINE; LACTOSE; PHENYLALANINE; REPRESSOR PROTEIN; TRYPTOPHAN;

ALLOSTERISM; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN QUATERNARY STRUCTURE; PROTEIN STRUCTURE;

ALLOSTERIC REGULATION; ASPARTIC ACID; BACTERIAL PROTEINS; BINDING, COMPETITIVE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HISTIDINE; HYDROGEN-ION CONCENTRATION; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN CONFORMATION; REPRESSOR PROTEINS;

EID: 0033596862     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982577n     Document Type: Article

References (55)

1. Miller, J. H., and Reznikoff, W. S. (1980) The Operon, 2nd ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
2. Müller-Hill, B., Rickenberg, H. V., and Wallenfels, K. (1964) J. Mol. Biol. 10, 303-318.
3. Gilbert, W., and Müller-Hill, B. (1966) Proc. Natl. Acad. Sci. U.S.A. 56, 1891-1898.
4. Gilbert, W., and Müller-Hill, B. (1967) Proc. Natl. Acad. Sci. U.S.A. 58, 2415-2421.
5. Barkley, M. D., Riggs, A. D., Jobe, A., and Bourgeois, S. (1975) Biochemistry 14, 1700-1712.
6. Dunaway, M., Olson, J. O., Rosenberg. J. M., Kallai, O. B., Dickerson, R. E., and Matthews, K. S. (1980) J. Biol. Chem. 255, 10115-10119.
7. O'Gorman, R. B., Rosenberg, J. M., Kallai, O. B., Dickerson, R. E., Itakura, K., Riggs, A. D., and Matthews, K. S. (1980) J. Biol. Chem. 255, 10107-10114.
8. Pfahl, M., Stockier, C., and Gronenborn, B. (1974) Genetics 76, 669-679.
9. Files, J. G., and Weber, K. (1976) J. Biol. Chem. 251, 3386-3391.
10. Miller, J. H. (1979) J. Mol. Biol. 131, 249-258.
11. Kleina, L. G., and Miller, J. H. (1990) J. Mol. Biol. 212, 295-318.
12. Markiewicz, P., Kleina, L. G., Cruz, C., Ehret, S., and Miller, J. H. (1994) J. Mol. Biol. 240, 421-433.
13. Friedman, A. M., Fischmann, T. O., and Steitz, T. A. (1995) Science 268, 1721-1727.
14. Lewis, M., Chang, G., Horton, N. C., Kercher, M. A., Pace, H. C., Schumacher, M. A., Brennan, R. G., and Lu, P. (1996) Science 271, 1247-1254.
15. Müller-Hill, B. (1971) Angrew. Chem., Int. Ed. Engl. 10, 160-172.
16. Adler, K., Beyreuther, K., Fanning, E., Geisler, N., Gronenborn, B., Klemm, A., Müller-Hill, B., Pfahl, M., and Schmitz, A. (1972) Nature 237, 322-327.
17. Jovin, T. M., Geisler, N., and Weber, K. (1977) Nature 269, 668-672.
18. Chuprina, V. P., Rullmann, J. A. C., Lamerichs, R. M. J. N., van Boom, J. H., Boelens, R., and Kaptein, R. (1993) J. Mol. Biol. 234, 446-462.
19. Schmitz, A., Schmeissner, U., Miller, J. H., and Lu, P. (1976) J. Biol. Chem. 251, 3359-3366.
20. Müller-Hill, B. (1983) Nature 302, 163-164.
21. Sams, C. F., Vyas, N. K., Quiocho, F. A., and Matthews, K. S. (1984) Nature 310, 429-430.
22. Nichols, J. C., Vyas, N. K., Quiocho, F. A., and Matthews, K. S. (1993) J. Biol. Chem. 268, 17602-17612.
23. Chakerian, A. E., Tesmer, V. M., Manly, S. P., Brackett, J. K., Lynch, M. J., Hoh, J. T., and Matthews, K. S. (1991) J. Biol. Chem. 266, 1371-1374.
24. Alberti, S., Oehler S., von Wilcken-Bergmann, B., Krämer, H., and Müller-Hill, B. (1991) New Biol. 3, 57-62.
25. Chen, J., and Matthews, K. S. (1992) J. Biol. Chem. 267, 13843-13850.
26. Chakerian, A. E., and Matthews, K. S. (1991) J. Biol. Chem. 266, 22206-22214.
27. Chang, W.-I., Olson, J. S., and Matthews, K. S. (1993) J. Biol. Chem. 268, 17613-17622.
28. Chang, W.-I., Barrera, P., and Matthews, K. S. (1994) Biochemistry 33, 3607-3616.
29. Pace, H. C., Kercher, M. A., Lu, P., Markiewicz, P., Miller, J. H., Chang, G., and Lewis, M. (1997) Trends Biochem. Sci. 22, 334-339.
30. Spronk, C. A. E. M., Slijper, M., van Boom, J. H., Kaptein, R., and Boelens, R. (1996) Nat. Struct. Biol. 3, 916-919.
31. Schumacher, M. A., Choi, K. Y., Zalkin, H., and Brennan, R. G. (1994) Science 266, 763-770.
32. Schumacher, M. A., Choi, K. Y., Lu, F., Zalkin, H., and Brennan, R. G. (1995) Cell 83, 147-155.
33. Kunkel, T. A. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 488-492.
34. Li, L., and Matthews, K. S. (1995) J. Biol. Chem. 270, 10640-10649.
35. O'Gorman. R. B., Dunaway, M., and Matthews, K. S. (1980) J. Biol. Chem. 255, 10100-10106.
36. Barry, J. K., and Matthews, K. S. (1997) Biochemistry 36, 15632-15642.
37. Riggs, A. D., Bourgeois. S., Newby, R. F., and Conn, M. (1968) J. Mol. Biol. 34, 365-368.
38. Wong, I., and Lohman, T. M. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 5428-5432.
39. Laiken, S. L., Gross, C. A., and von Hippel, P. H. (1972) J. Mol. Biol. 66, 143-155.
40. Daly, T. J., Olson, J. S., and Matthews, K. S. (1986) Biochemistry 25, 5468-5474.
41. Sommer, H., Lu, P., and Miller, J. H. (1976) J. Biol. Chem. 251, 3774-3779.
42. Bandyopadhyay, P. K., and Wu, C.-W. (1979) Arch. Biochem. Biophys. 195, 558-564.
43. Gardner, J. A., and Matthews, K. S. (1990) J. Biol. Chem. 265, 21061-21067.
44. Bourgeois, S. (1971) Methods Enzymol. 21, 491-500.
45. Chen, J., and Matthews, K. S. (1994) Biochemistry 33, 8728-8735.
46. Daly, T. J., and Matthews, K. S. (1986) Biochemistry 25, 5479-5484.
47. Johnson, M. L., and Frasier, S. G. (1985) Methods Enzymol. 117, 301-342.
48. Ohshima, Y., Mizokoshi, T., and Horiuchi, T. (1974) J. Mol. Biol. 89, 127-136.
49. Friedman, B. E., Olson, J. S., and Matthews, K. S. (1977) J. Mol. Biol. 111, 27-39.
50. Monod, J., Wyman, J., and Changeux, J.-P. (1965) J. Mol. Biol. 12, 88-118.
51. Müller-Hartmann, H., and Müller-Hill, B. (1996) J. Mol. Biol. 257, 473-478.
52. Daly, T. J., and Matthews, K. S. (1986) Biochemistry 25, 5474-5478.
53. Suckow, J., Markiewicz, P., Kleina, L. G., Miller, J., Kisters-Woike, B., and Müller-Hill, B. (1996) J. Mol. Biol. 261, 509-523.
54. Waldburger, C. D., Schildbach, J. F., and Sauer, R. T. (1995) Nat. Struct. Biol. 2, 122-128.
55. Carson, M. (1987) J. Mol. Graphics 5, 103-106.