Perturbation from a Distance: Mutations that Alter LacI Function through Long-Range Effects

Biochemistry

Volumn 42, Issue 47, 2003, Pages 14004-14016

  Swint Kruse, Liskin ^a   Zhan, Hongli ^a   Fairbanks, Bonnie M ^a,b   Maheshwari, Atul ^a,c   Matthews, Kathleen S ^a  

^a RICE UNIVERSITY   (United States)

^b AUBURN UNIVERSITY   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CONFORMATIONS; MOLECULAR DYNAMICS; MOLECULAR STRUCTURE; MUTAGENESIS;

BINDING AFFINITY; INDUCER-BINDING SITES;

PROTEINS;

ISOPROPYL BETA DEXTRO THIOGALACTOSIDE; LACTOSE REPRESSOR PROTEIN; MUTANT PROTEIN; REPRESSOR PROTEIN; THIOGLYCOSIDE; UNCLASSIFIED DRUG; UREA;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; DENATURATION; DNA FLANKING REGION; GENE MUTATION; GENE REPRESSION; LINKAGE ANALYSIS; OPERATOR GENE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN STRUCTURE; PROTEIN VARIANT; ULTRAVIOLET SPECTROSCOPY; WILD TYPE;

AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; DNA-BINDING PROTEINS; ESCHERICHIA COLI PROTEINS; ISOPROPYL THIOGALACTOSIDE; LACTOSE; MELIBIOSE; MUTAGENESIS, SITE-DIRECTED; OPERATOR REGIONS (GENETICS); PHENOTYPE; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; UREA;

EID: 0344412958     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035116x     Document Type: Article

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