Genetic studies of the Lac repressor XV: 4000 single amino acid substitutions and analysis of the resulting phenotypes on the basis of the protein structure

Journal of Molecular Biology

Volumn 261, Issue 4, 1996, Pages 509-523

  Suckow, Jörg ^a   Markiewicz, Peter ^b   Kleina, Lynn G ^c   Miller, Jeffrey ^b   Kisters Woike, Brigitte ^a   Müller Hill, Benno ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c PLUM ISLAND ANIMAL DISEASE CENTER   (United States)

Author keywords

Functional analysis; Lac repressor; Molecular modeling; Phenotype analysis; Pur repressor

Indexed keywords

DNA BINDING PROTEIN; HELIX LOOP HELIX PROTEIN; ISOPROPYL THIOGALACTOSIDE; MUTANT PROTEIN; REPRESSOR PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; LACTOSE OPERON; MOLECULAR MODEL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; X RAY ANALYSIS;

EID: 2342519701     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0479     Document Type: Article

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